急性一氧化碳中毒生化指标与迟发脑病的相关性研究

0 引言
在临床上，由毒性气体损伤导致的疾病则为急性一氧化碳中 毒，而 迟 发 脑 病 则 为 其 最 严 重 的 并 发 症，此 类 患 者 主 要 表 现 精 神 神经系统症状，其中最常见的即为痴呆 。 [1-3] 由于该病症检出率 低、致 残 率 高，且 发 病 机 制 复 杂，因 而 临 床 漏 诊、误 诊 情 况 经 常 发 生 。 [4-5] 因此本文对急性一氧化碳中毒生化指标与迟发脑病的相 关性进行了研究与分析，现具体报道如下。
FAN Ling-yun
(Shanxi Integrated Traditional Chinese and Western Medicine Hospital, Taiyuan Shanxi)
ABSTRACT: Objective To study the correlation and analysis of biochemical indexes of acute carbon monoxide poisoning and delayed encephalopathy. Methods 204 cases of patients with acute carbon monoxide as the research object in our hospital from October 2012 to February 2016 were poisoning, according to its non delayed encephalopathy were divided into two groups: control group (no) and observation group (with), each of 102 cases. Two groups were treated with latex turbidimetric method and enzyme immunoassay of serum C- reactive protein and plasma homocysteine level and other biochemical indicators were detected. The detection results were compared between the two groups. Results In the observation group, the serum C- reactive protein and plasma homocysteine The biochemical index level, significantly higher compared with the control group, P<0.05 comparison and the difference between groups, with statistical significance. Conclusion Acute carbon monoxide poisoning patients with delayed encephalopathy after the serum Creactive protein and plasma homocysteine level and other biochemical indicators increased significantly, so acute carbon monoxide poisoning and biochemical indexes and delayed encephalopathy have certain relevance, can provide the basis for clinical diagnosis and treatment of delayed encephalopathy. KEY WORDS: Acute carbon monoxide poisoning; Delayed encephalopathy; Biochemical index; Correlation
本文引用格式：樊凌云 . 急性一氧化碳中毒生化指标与迟发脑病的相关性研究 [J]. 世界最新医学信息文摘 ,2019,19(42):140-141.
Study on the Correlation between Biochemical Indexes of Acute Carbon Monoxide Poisoning and Delayed Encephalopathy
140
World Latest Medicine Information (Electronic Version) 2019 Vo1.19 No.42
·临床研究·
急性一氧化碳中毒生化指标与迟发脑病的相关性研究
ቤተ መጻሕፍቲ ባይዱ
樊凌云
（山西省中西医结合医院脑病科，山西 太原）
摘要：目的 研究与分析急性一氧化碳中毒生化指标与迟发脑病的相关性。方法 选取我院 2016 年 10 月至 2018 年 2 月收治的急性一氧化碳 中毒患者 204 例为研究对象，将其按有无迟发脑病分为两组，即对照组（无）与观察组（有），各 102 例。两组均采用胶乳比浊法和酶联免疫 分析法对血清 C- 反应蛋白以及血浆同型半胱氨酸等生化指标水平分别进行检测。比较两组检测结果。结果 观察组的血清 C- 反应蛋白以及血 浆同型半胱氨酸等生化指标水平，与对照组相比显著较高，且组间对比差异 P<0.05，具有统计学意义。结论 急性一氧化碳中毒患者出现迟发 脑病后，其血清 C- 反应蛋白以及血浆同型半胱氨酸等生化指标水平升高显著，因此急性一氧化碳中毒生化指标与迟发脑病具有一定相关性， 可为迟发脑病的临床诊治提供依据。 关键词：急性一氧化碳中毒；生化指标；迟发脑病；相关性 中图分类号：R747.9 文献标识码：A DOI: 10.19613/ki.1671-3141.2019.42.067