欧龙马滴剂用于小儿鼻-鼻窦炎的近远期疗效及安全性观察

9.0%袁差异有统计学意义渊P 约 0.05冤遥 结论 与沐舒坦糖浆比较袁欧龙马滴剂能进一步改善鼻-鼻窦炎患儿症状袁
近远期疗效显著袁其中小剂量给药不仅能取得理想治疗效果袁而且不良反应发生率低袁值得临床推广遥
[关键词] 鼻-鼻窦炎曰欧龙马滴剂曰治疗效果曰安全性
[中图分类号] R765.4
[文献标识码] A
mL/time, 1-6 years old children of group B were given the dose of 2 mL/time, >6-12 years old mL/time, group C was
given Mu Shu Tan syrup treatment, 1-6 children 2.5 mL/time, >6-12 years old 5 mL/time. The clinical efficacy of the
[文章编号] 1673-72m efficacy and safety of Oulongma Drops in children with nasal-
sinusitis
MENG Xiangtao1 Y A NG Xiao2
1.Department of ENT, Zhuozhou City Hospital, Hebei Province, Baoding 072750, China; 2.Department of Paediatrics,
test-20 (SNOT-20) scale and the adverse events were recorded. Results The total effective rates of group A and group
B were 90.0% and 89.0% respectively, which were higher than that of group C (72.0%), the difference was statistically
1 月~2017 年 1 月涿州市医院收治的鼻-鼻窦炎患儿 300 例袁 采用随机数字表法将其分为 A尧B尧C 三组袁 每组各
100 例遥 A 组和 B 组均采用欧龙马滴剂治疗袁其中 A 组 1~6 岁起始剂量为 4 mL/次袁于 5 d 后调整为 2 mL/次曰>6~
12 岁儿童为 6 mL/次袁于 5 d 后改为 3 mL/次曰B 组 1~6 岁患儿给药剂量为 2 mL/次袁>6~12 岁为 3 mL/次曰C 组予
Zhuozhou City Hospital, Hebei Province, Baoding 072750, China
[Abstract] Objective To explore the long-term efficacy of Oulongma Drops in children with nasal sinusitis and to ana鄄
number table, patients of the group A and group B were treated with Oulongma Drops, 1-6-year-old children of group
A with starting dose of 4 mL/time, after 5 d adjusted to 2 mL/time, >6-12 years old children 6 mL/time, after 5 d to 3
渊P 约 0.05冤遥A尧B尧C 三组治疗 3 个月后的总有效率分别为 88.0%尧86.0%及 61.0%袁复发率分别为 2.0%尧3.0%及 11.0%袁C
组总有效率低于 A 组和 B 组袁复发率高于 A 组和 B 组袁差异有统计学意义渊P 约 0.05冤遥 A尧B 组治疗后的鼻塞尧黏
膜充血评分均低于 C 组袁差异有统计学意义渊P 约 0.05冤遥 B 组不良反应发生率为 2.0%袁低于 A 组和 C 组的 9.0%和
two groups in 1 and 3 months after treatment were observed, and the recurrence rate was analyzed after 8 months fol鄄
low-up. The nasal, mucosal hyperemia, sleep disorders, runny nose scores were assessed by the nasal sinus outcome
lyze the safety of treatment. Methods A total of 300 cases of nasal-sinusitis were enrolled in Zhuozhou City Hospital
from January 2016 to January 2017. They were divided into 100 cases of group A, B and C according to the random
以沐舒坦糖浆治疗袁1~6 岁儿童 2.5 mL/次袁>6~12 岁为 5 mL/次遥 观察两组治疗 1尧3 个月的临床疗效袁并随访 8 个
月袁分析复发率遥 利用鼻腔鼻窦结局测试-20渊SNOT-20冤量表评估鼻塞尧黏膜充血尧睡眠障碍尧流涕评分袁并记录用
药后不良反应发生情况遥 结果 A尧B 组总有效率分别为 90.0%和 89.0%袁高于 C 组的 72.0%袁差异有统计学意义
窑 妇幼医学 窑
中国医药导报 2018 年 6 月第 15 卷第 18 期
欧龙马滴剂用于小儿鼻 - 鼻窦炎的近远期疗效 及安全性观察
孟祥涛 1 杨 霄 2 1.河北省涿州市医院耳鼻喉科袁河北保定 072750曰2.河北省涿州市医院儿科袁河北保定 072750
[摘要] 目的 探讨欧龙马滴剂在小儿鼻-鼻窦炎治疗中的近远期疗效袁分析该药治疗安全性遥 方法 纳入 2016 年