Identification of immunoglobulin (lg) disorders us
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专利名称：Identification of immunoglobulin (lg)
disorders using fourier transform infrared
spectroscopy
发明人：Christopher B. Riley,J. Trenton McClure,R.
Anthony Shaw
申请号：US12175022
申请日：20080717
公开号：US08421019B2
公开日：
20130416
专利内容由知识产权出版社提供
专利附图：
摘要：A method and a corresponding system for obtaining a serum mid-infrared
spectroscopic profile using Fourier-transform infrared spectroscopy (FTIR) are described. The method comprises acquiring FTIR spectra for dried sera and preprocessing the FTIR spectra of sera by differentiation and smoothing to enhance weak spectral features and to remove baseline variations. The preprocessed FTIR spectra are normalized to a common intensity range, the normalization being performed in a spectral sub-region defined by strongest infrared (IR) absorption for a protein to obtain the serum spectroscopic profile. The serum spectroscopic profiles provide a basis to diagnose immunoglobulin disorders or to quantify serum immunoglobulin levels.
申请人：Christopher B. Riley,J. Trenton McClure,R. Anthony Shaw
地址：Ten Mile House CA,Charlottetown CA,Winnipeg CA
国籍：CA,CA,CA
代理机构：Nixon & Peabody LLP
代理人：David S. Resnick
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