微创穿刺引流联合开颅减压治疗高血压脑出血突发脑疝的疗效分析及其对脑部血流和预后的影响

微创穿刺引流联合开颅减压治疗高血压脑出血突发脑疝的疗效分析及其对脑部血流和预后的影响
李奎智;雷国亮;张成贵
【期刊名称】《中国医药导报》
【年(卷),期】2018(015)014
【摘要】目的探讨微创穿刺引流联合开颅减压术治疗高血压脑出血突发脑疝患者的效果及其对脑部血流和预后的影响.方法收集2015年10月～2017年10月于石家庄市第一医院神经外科接受手术治疗的96例高血压脑出血突发脑疝患者的临床资料,按照手术方式不同分为在开颅血肿清除及去骨瓣减压术前采用微创穿刺引流治疗的观察组(48例),常规开颅血肿清除及去骨瓣减压治疗的对照组(48例).观察记录并比较两组患者经颅多普勒超声(TCD)检查大脑中动脉平均流速(Vm)、大脑中动脉搏动指数(PI)、疗效、神经功能缺损量表(NHISS)评分、格拉斯哥预后评分(GOS)、日常生活能力评定指数(BI)值.结果观察组总有效率为91.67％,高于对照组的75.00％,差异有统计学意义(P＜0.05).两组患者术后7d、术后1个月及术后3个月的Vm和PI与术前比较,差异均有统计学意义(P＜0.05).两组患者术后7d、术后1个月及术后3个月的Vm、PI比较,差异有统计学意义(P＜0.05);观察组GOS 评分情况显著优于对照组,术后3个月观察组BI评分显著高于对照组,差异均有统计学意义(P＜0.05).结论微创穿刺引流联合开颅减压术治疗高血压脑出血突发脑疝的效果、脑血流情况和预后优于常规开颅减压术,是高血压脑出血突发脑疝患者抢救的有效方法.%Objective To explore the effect of minimally invasive puncture drainage combined with craniotomy in the treatment of hypertensive cerebral hemorrhage with sudden cerebral hemia and its effect on cerebral
blood flow and prognosis.Methods Clinical data of 96 hypertensive intracerebral hemorrhage patients with sudden brain hernia from October 2015 to October 2017 were collected.According to the different operation method,forty-eight cases of minimally invasive puncture and drainage befor the craniotomy evacuation of hematoma and decompressive craniectomy were selected as observation group,and 48 cases of conventional treatment before the craniotomy evacuation of hematoma and decompressive craniectomy as control group.The TCD parameters,curative effect,NHISS score,GOS score and BI value of two groups were observed and compared.Results The total effective rate of the observation group was 91.67％,was higher than that of the control group (75.00％),the difference was statistically significant (P ＜ 0.05).Compared with before operation,there were significant differences in Vm and PI 7 days,1 month and 3 months after operation of the two groups (P ＜
0.05),there were significant differences in Vm and PI 7 days,1 month and 3 months after operation between the two groups (P ＜ 0.05).GOS score of the observation group was better than that of the control group,and BI score 3 months after operation was significantly better than that of the control group,the differences were statistically significant (P ＜
0.05).Conclusion The curative effect and cerebral blood flow and prognosis of minimally invasive drainage combined with craniotomy for the patients of hypertensive cerebral hemorrhage with sudden cerebral hernia are better than conventional craniotomy.It is an effective method for the patients of hypertensive cerebral hemorrhage with sudden cerebral hernia.
【总页数】4页(P50-53)
【作者】李奎智;雷国亮;张成贵
【作者单位】河北省石家庄市第一医院神经外科二病区,河北石家庄050000;河北省石家庄市第一医院神经外科二病区,河北石家庄050000;河北省石家庄市第一医院神经外科二病区,河北石家庄050000
【正文语种】中文
【中图分类】R74.34
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