GLP1类似蛋白Exendin4抗体说明书

GLP1类似蛋白Exendin4抗体说明书
中文名称 GLP1类似蛋白Exendin4抗体
英文名称 Exendin 4
别名 Exendin 4; Exendin4; Exendin4; EXE4_HELSU .
供应商远慕生物
研究领域免疫学神经生物学糖尿病
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Gila monster lizard
产品应用 WB=1:100500 ELISA=1:5001000 IP=1:20100
IHCP=1:100500 IHCF=1:100500 IF=1:100500 GLP1类似蛋白Exendin4抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 4.3kDa
性状 Lyophilized or Liquid
浓度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from Gila monster lizard Exendin 4
亚型 IgG
纯化方法 affinity purified by Protein A
储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件Store at 20 °C for one year. Avoid repeated
freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater
than a year when kept at 20°C. When reconstituted in
sterile pH 7.4 0.01M PBS or diluent of antibody the
antibody is stable for at least two weeks at 24 °C.
GLP1类似蛋白Exendin4抗体产品介绍 background:
Exendin 4 is a 39 amino acid peptide found in venom from
the Gila monster Helicoderma suspectum. It is a member of
the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. Function:
Venom protein that mimics the incretin hormone glucagonlike peptide 1 (GLP1). It stimulates insulin synthesis and secretion, protects against betacell apoptosis in response
to different insults, and promotes betacell proliferation.
It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP1 receptor (GLP1R). Induces
hypotension that is mediated by relaxation of cardiac smooth muscle.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed by the venom gland.
Similarity:
Belongs to the glucagon family.
Database links:
UniProtKB/SwissProt: P26349.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.。