TETRAZOLIUM SALT COMPOUND AND METHOD FOR MEASURING
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专利名称：TETRAZOLIUM SALT COMPOUND AND METHOD FOR MEASURING
ABSORPTIOMETRY OF DEHYDROGENASE
USING SAID COMPOUND
发明人：SHIGA TADANOBU
申请号：JP21224483
申请日：19831110
公开号：JPS59112973A
公开日：
19840629
专利内容由知识产权出版社提供
摘要：NEW MATERIAL:A compound of the formula (Y is 2-4C straight chain alkylene which may have a side chain or further one OH group R<1> is 1-4C alkyl or hydroxyethyl; R<2> is 1-4C alkyl which may have 1-2 OH groups or one phenyl group; X is Cl or Br; W is NO2; Z is 4-iodophenyl). USE:A compound for measuring the absorptiometry of dehydrogenases useful for diagnosis of cardiac infarction, malignant tumors and progressive atrophy. PROCESS:3-hydroxybenzaldehyde is reacted with epichlorohydrin under basic conditions to synthesize a 3-alkoxybenzaldehyde, which is then reacted with a phenylhydrazine to give a hydrazone compound. The resultant hydrazone compound is then coupled with a 4-iodobenzene diazonium salt under basic conditions to afford a formazan, which is converted into a quaternary ammonium salt. The resultant quaternary ammonium salt is then reacted with an oxidizing agent to give the aimed substance.
申请人：DOUJIN KAGAKU KENKYUSHO:KK
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