Mycoplasma hyopneumoniae bacterin vaccine
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专利名称：Mycoplasma hyopneumoniae bacterin vaccine
发明人：WUMIN LI,HSIEN-JUE (STEVE)
CHU,ZHICHANG XU
申请号：AU2002228993
申请日：20011211
公开号：AU2002228993B2
公开日：
20060629
专利内容由知识产权出版社提供
摘要：The invention provides an improved Mycoplasma hyopneumoniae bacterin vaccine composition, which advantageously provides immunity from infection after a single administration. The composition comprises an inactivated Mycoplasma hyopneumoniae bacterin and an adjuvant mixture, which, in combination, provide immunity from Mycoplasma hyopneumoniae infection after a single administration, and elicit an immune response specific to Mycoplasma hyopneumoniae bacterin and including cell-mediated immunity and local (secretory IgA) immunity. In a preferred embodiment, the adjuvant mixture comprises an acrylic acid polymer, most preferably Carbopol, and a mixture of a metabolizable oil such as one or more unsaturated terpene hydrocarbons, preferably squalene or squalane, and a polyoxyethylene-polypropylene block copolymer such as Pluronic(R). The vaccine composition may optionally include a preservative, preferably thimerosol and/or EDTA.
申请人：WYETH
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