琥珀酸美托洛尔和吲达帕胺联用治疗高血压的临床效果研究
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琥珀酸美托洛尔和吲达帕胺联用治疗高血压的临床效果研究刘哲;崔健丽
【摘要】目的:深入研究倍他乐克(琥珀酸美托洛尔)与吲达帕胺对高血压病患的治疗效果。方法选取2013年3月~2014年3月在我院接受住院治疗的高血压病患90人,将这些病患随机分成两组,实验组与对照组,每组共有病患45人,为对照组中的病患提供吲达帕胺药物进行治疗,为实验组中的病患联合提供吲达帕胺与倍他乐克药物进行治疗,连续治疗2个月后,观察药物对两组病患的代谢、血压、电解质、心电图的影响,并使用统计学方法对比分析两组病患的治疗总有效率。结果实验组中病患的治疗总有效率为95.6%,对照组中病患的治疗总有效率为80%,实验组高于对照组,P <0.05,具有统计学差异意义。结论在临床治疗高血压病患时,联合使用吲达帕胺与倍他乐克药物,不仅治疗效果好,而且副作用小。%Objective In order to further study of betaloc with indapamide treatment effects of hypertensive patients. Methods From March 2013 to March 2014 in our hospital to accept hypertension patients hospitalized with 90 people, these patients were randomly divided into two groups, experimental group and control group, each group a total of 45 patients, the patients in control group with indapamide drug treatment, the patients in experimental group combined with indapamide and betaloc drug treatment,after treatment for 2 months in a row, observe the metabolism of the drugs on two groups of patients, blood pressure, electrolyte, the influence of the electrocardiogram , and the use of statistical methods comparative analysis of two groups of patients with total effective treatment. Results The treatment of patients in experimental group total
effective rate was 95.6%, the treatment of patients in the control group total effective rate was 80%, and the experimental group was higher than the control group, P<0.05, statistically significance. Conclusion Patients with clinical treatment of high blood pressure, combined with indapamide and betaloc drugs, not only the treatment effect is good, and small side effects, should promote the use scope in the clinical treatment.
【期刊名称】《中国继续医学教育》
【年(卷),期】2015(000)025
【总页数】2页(P156-157)
【关键词】倍他乐克;吲达帕胺;高血压;治疗效果
【作者】刘哲;崔健丽
【作者单位】130000 吉林省长春市吉林大学第四医院;130000 吉林省长春市吉林大学第四医院
【正文语种】中文
【中图分类】R544.1
作者单位: 130000 吉林省长春市吉林大学第四医院
after treatment for 2 months in a row, observe the metabolism of the drugs on two groups of patients, blood pressure, electrolyte, the influence of the electrocardiogram , and the use of statistical methods comparative analysis of two groups of patients with total effective treatment. Results The treatment of patients in experimental group total effective rate was
95.6%, the treatment of patients in the control group total effective rate was 80%, and the experimental group was higher than the control group, P<0.05, statistically significance. Conclusion Patients with clinical treatment of high blood pressure, combined with indapamide and betaloc drugs, not only the treatment effect is good, and small side effects, should promote the use scope in the clinical treatment.
怎样控制高血压,使其能够在短时间内快速降到正常水平,并尽量减少药物服用剂量[1],已经成为有关医学专家的共同研究课题。倍他乐克与吲达帕胺均为降压药物,文章对比分析在我院使用以上两种药物进行高血压治疗患者的治疗效果,现进行如下报道。
1.1 基本资料
选取2013年3月~2014年3月在我院接受住院治疗的高血压患者90人,将这些患者随机分成实验组与对照组,每组45人。实验组中,男性27人,女性18人;年龄最小38岁,最大76岁,平均年龄为(57.2±2.6)岁;病程最短1年,最长29年,平均病程为(12.5±2.4)年。对照组中,男性25人,女性20人;年龄最小40岁,最大79岁,平均年龄为(55.3±2.9)岁;病程最短2年,最长26年,平均病程为(11.7±3.2)年。本次研究的患者均通过1999年国际卫生组织颁布的《高血压诊断标准》确诊,收缩压(SBP)≥140 mm Hg,舒张压(DBP)≥90 mm Hg,并排除严重心脑血管疾病、肾功能衰竭、继发性高血压等病症。对比两组患者的年龄、性别、病程等临床基本资料,P>0.05,可以对比。
1.2 治疗方法
为对照组中的患者提供吲达帕胺进行治疗,每天一次,每次1.25 mg,早饭后口服。为实验组中的患者联合提供吲达帕胺与12.5 mg的倍他乐克联合治疗,连续治疗2个月。