胃转流术对胃癌合并2型糖尿病患者血糖影响的临床研究

胃转流术对胃癌合并2型糖尿病患者血糖影响的临床研究侯建忠;何家赓;木拉提;牛建华
【期刊名称】《中外医疗》
【年(卷),期】2015(000)012
【摘要】Objective To explore the influence of blood glucose in gastric cancer patients with type 2 diabetes by Roux-en-Y gastric bypass. Methods Retrospective analysis 52 gastric cancer patients with type 2 diabetes mellitus who underwent Roux-en-Y gastric bypass, observed data as fasting blood-glucose(FBG) ,2-Hour postprandial blood sugar(2hPG), Glycosylated hemoglobin (HbA1c) and body mass index (BMI), and details before and in 1,3,6 months after operation. Close attention to the use of hypo-glycemic drugs after operation. Results After with Roux-en-Y reconstruction of gastrointestinal surgery, there were significant dif-ferences of FBG and 2hPG (P<0.05) in all patients, along with the improvement in blood glucose, there was significant difference of HbA1c (P<0.05); there was no significant difference of BMI in each period after surgery compare with preoperative. In 52 pa-tients,8 cases (15.3%) reached the normal level of blood glucose after operation, discontinued antidiabetic drugs;17 cases (32.7%) withdrawal within 3 months after operation;9 cases (17.3%) after 3-6 months withdrawal;18 cases (34.6%) in the postoperative 6 month still in use of hypoglycemic drugs but the drug dosage was impassability degree reduced, at present still in follow-up.
Con-clusion The study shows that the Roux-en-Y gastric bypass is aneffective method for the type 2 diabetes mellitus.%目的：探讨Roux-en-Y 消化道重建术对胃癌合并2型糖尿病患者血糖的影响。

方法回顾性分析该院于2010年-2014年6月收治的52例以Roux-en-Y消化道重建行手术治疗的胃癌合并2型糖尿病患者，比较术前、术后1、3、6个月的空腹血糖、餐后2 h血糖、
糖化血红蛋白(HbA1c)、体重指数(BMI)的变化情况，密切关注术后的降糖药物使
用情况。

结果Roux-en-Y消化道重建术术后所有患者的空腹及餐后血糖均较术前逐渐降低(P<0.05),伴随着术后血糖的改善，HbA1c较术前逐渐下降(P<0.05)；患者术后各时间段BMI较术前均无明显变化(P>O.05)。

52例患者中，8例(15.3%)
术后出院时血糖达正常水平，停用降糖药物；17例(32.7%)于术后3个月内停药；9例(17.3%)于术后3~6个月停药；18例(34.6%)于术后6个月仍在使用降糖药物，但用药剂量均有不通程度的减少，目前仍在随访。

结论Roux-en-Y消化道重建术是治疗2型糖尿病的有较方法。

【总页数】3页(P80-82)
【作者】侯建忠;何家赓;木拉提;牛建华
【作者单位】石河子大学医学院第一附属医院胃肠甲状腺外科，新疆石河子832008;石河子大学医学院第一附属医院胃肠甲状腺外科，新疆石河子 832008;石河子大学医学院第一附属医院胃肠甲状腺外科，新疆石河子 832008;石河子大学
医学院第一附属医院胃肠甲状腺外科，新疆石河子 832008
【正文语种】中文
【中图分类】R73
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