A Successful Online Pharmacy in Australia

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制药工程专业英语课后练习题含答案 (2)

制药工程专业英语课后练习题含答案 (2)

制药工程专业英语课后练习题含答案题目一:Drug Substance Manufacturing1.What is Drug Substance Manufacturing?–A. It is the process of producing a finished drug product.–B. It is the process of producing the activeingredient or drug substance used in a drug product.–C. It is the process of packaging and labeling a finished drug product.–D. It is the process of performing clinical trials ona drug product.Answer: B. It is the process of producing the active ingredient or drug substance used in a drug product.2.What are the steps involved in Drug Substance Manufacturing?–A. Synthesis, isolation, and purification.–B. Packaging, labeling, and testing.–C. Clinical trials, manufacturing, and distribution.–D. None of the above.Answer: A. Synthesis, isolation, and purification.3.What is the mn purpose of Drug Substance Manufacturing?–A. To produce a finished drug product for human use.–B. To provide the active ingredient or drug substance used in a drug product.–C. To test and validate the safety and efficacy of a drug product.–D. To distribute a drug product to consumers.Answer: B. To provide the active ingredient or drug substance used in a drug product.题目二:Pharmaceutical Formulation1.What is Pharmaceutical Formulation?–A. It is the process of producing a finished drug product.–B. It is the process of selecting and combining ingredients to produce a drug product.–C. It is the process of packaging and labeling a finished drug product.–D. It is the process of performing clinical trials ona drug product.Answer: B. It is the process of selecting and combining ingredients to produce a drug product.2.What are the key considerations in PharmaceuticalFormulation?–A. Safety, efficacy, and stability.–B. Cost, avlability, and taste.–C. Appearance, texture, and smell.–D. None of the above.Answer: A. Safety, efficacy, and stability.3.What is the role of excipients in Pharmaceutical Formulation?–A. They are the active ingredients in a drug product.–B. They are the inactive ingredients in a drug product that help to improve its properties.–C. They are the ingredients in a drug product that are responsible for the color and flavor.–D. None of the above.Answer: B. They are the inactive ingredients in a drug product that help to improve its properties.题目三:Good Manufacturing Practice (GMP)1.What is Good Manufacturing Practice (GMP)?–A. It is a set of regulations and guidelines that ensure the quality and safety of pharmaceutical products.–B. It is a set of regulations and guidelines that ensure the efficacy of pharmaceutical products.–C. It is a set of regulations and guidelines that ensure the affordability of pharmaceutical products.–D. None of the above.Answer: A. It is a set of regulations and guidelines that ensure the quality and safety of pharmaceutical products.2.What are the key components of Good Manufacturing Practice(GMP)?–A. Quality control, documentation, and facility design.–B. Clinical trials, manufacturing, and distribution.–C. Cost control, inventory management, and customer service.–D. None of the above.Answer: A. Quality control, documentation, and facility design.3.Why is Good Manufacturing Practice (GMP) important?–A. It helps to ensure the quality and safety ofpharmaceutical products.–B. It helps to reduce the cost of producingpharmaceutical products.–C. It helps to increase the avlability ofpharmaceutical products.–D. None of the above.Answer: A. It helps to ensure the quality and safety of pharmaceutical products.总结本文介绍了制药工程专业英语中的几个重要概念和术语,包括Drug Substance Manufacturing(药品物质制造)、Pharmaceutical Formulation(制剂开发)以及Good Manufacturing Practice(良好生产规范)。

宜昌2024年03版小学5年级下册第5次英语第二单元自测题

宜昌2024年03版小学5年级下册第5次英语第二单元自测题

宜昌2024年03版小学5年级下册英语第二单元自测题考试时间:90分钟(总分:120)A卷考试人:_________题号一二三四五总分得分一、综合题(共计100题)1、听力填空题:I think it’s important to stay healthy. Eating nutritious foods and exercising regularly helps me feel my best. I enjoy __________ as my favorite way to stay active.2、听力题:The first successful vaccine was developed for _______.3、听力题:The discovery of fire was an important step in _______ history.4、填空题:The koala eats _________ (桉树) leaves.5、听力题:The computer is very ___ (slow/fast).6、听力题:The chemical formula for potassium permanganate is _______.7、选择题:What do we call a large body of saltwater?A. RiverB. LakeC. OceanD. Pond8、填空题:I love to go ______ with my parents.9、What is the name of the famous dinosaur that is often depicted as being very large?A. Tyrannosaurus RexB. VelociraptorC. TriceratopsD. Brachiosaurus答案:A10、What is 6 + 3?A. 8B. 9C. 10D. 11答案:B11、What is the name of the famous American architect known for his innovative designs?A. Frank Lloyd WrightB. I.M. PeiC. Louis SullivanD. All of the above答案:D12、听力题:I have a _____ (新) friend.13、填空题:The capital of Egypt is _____.14、What do we call the act of writing a letter?A. CorrespondenceB. CommunicationC. MessagingD. Notifying答案:A15、填空题:The ________ (城市绿化) improves air quality.16、What do bees make?A. MilkB. HoneyC. BreadD. Cheese答案: B17、填空题:The ________ (雨水) helps plants grow strong.My friend saw a ______ (蜗牛) on the sidewalk.19、填空题:I like taking pictures of ________ (风景).20、填空题:The ________ loves to jump and explore.21、选择题:Which of these is a marine animal?A. EagleB. SharkC. LionD. Elephant22、听力题:My friend is a ______. He enjoys hiking.23、填空题:I want to make a __________ (名词) with my __________ (玩具名).24、填空题:My cat loves to chase _______ (小虫) around the house.25、填空题:My mom has a beautiful _____.26、听力题:The bird is ___ high. (flying)27、What is a common pet?A. TigerB. GoldfishC. ElephantD. Lion答案:B28、填空题:A ______ (生态区域) supports specific plants and animals.29、How do you say "water" in Spanish?A. AguaB. EauC. WasserD. VodaMy sister is a ______. She enjoys helping animals.31、What do we call the language spoken in Spain?A. FrenchB. ItalianC. SpanishD. Portuguese答案:C32、听力题:There are _____ (four/five) seasons in a year.33、听力题:A saturated solution has reached its _______ point.34、听力题:Fossils are found in ______ rocks, which form from layers of sediment.35、填空题:We have a ______ (快乐的) reunion every year.36、填空题:The starling can mimic other ______ (鸟) sounds.37、填空题:The __________ (历史的叙述者) play crucial roles in shaping narratives.38、听力题:The train is ______ (fast) and exciting.39、What do you call a person who creates visual art?A. ArtistB. DesignerC. PainterD. Sculptor答案:A40、听力题:A saturated solution is a solution that contains the maximum amount of ______.41、填空题:The country famous for its ancient civilization is ________ (埃及).42、听力题:The chemical formula for zinc oxide is __________.A catalyst speeds up a _______ without being consumed.44、 (96) is known for its history and architecture. 填空题:The ____45、What is the name of the fairy tale character who lost her glass slipper?A. RapunzelB. CinderellaC. Snow WhiteD. Belle答案:B46、What do you call a baby pig?A. CalfB. KidC. PigletD. Foal47、听力题:The _____ (围栏) is tall.48、What is the name of the famous giant red rock in Australia?A. UluruB. Ayers RockC. Great Barrier ReefD. Daintree答案:A49、填空题:My sister has a cute ________ (玩具名称).50、选择题:What is 20 - 8?A. 10B. 12C. 14D. 1651、填空题:When it rains, I love to watch the __________ flow. (水)52、填空题:He is a _____ (发明家) creating tech innovations.We are going to _____ a movie tonight. (watch)54、听力题:A __________ is a reaction that occurs slowly over time.55、听力题:The ________ (strategy) guides our efforts.56、听力题:The girl is very ________.57、What do we call a person who helps sick people?A. TeacherB. EngineerC. DoctorD. Artist答案:C58、What is the name of the famous American singer known for "Crazy"?A. Patsy ClineB. Taylor SwiftC. Carrie UnderwoodD. LeAnn Rimes答案: A59、填空题:My _______ (猫咪) loves to chase string.60、听力题:In a chemical equation, the products are shown on the _______.61、填空题:The owl is a nocturnal ______ (动物).62、填空题:I saw a _______ (小熊) playing in the forest.63、填空题:The __________ (历史的展望) shapes our vision for the future.64、How many letters are in the word "alphabet"?A. 6B. 7C. 8答案:C65、听力题:My ______ is a great cook.66、填空题:The ancient Greeks made significant advancements in ________ (科学).67、填空题:My aunt works in ____.68、填空题:_____ (土壤质量) affects plant growth.69、What do we call a young female goat?A. KidB. LambC. CalfD. Foal答案:A70、听力题:An atom is stable when its outer shell is ______.71、填空题:I enjoy going to the ______.72、填空题:I love to see the ______ (玫瑰) in the garden.73、填空题:The __________ (历史的启示) guide future actions.74、听力题:Earth's rotation causes day and ______.75、填空题:I love collecting interesting ______ (石头) when I go for walks.76、What is 8 3?a. 4b. 5c. 6答案:B77、填空题:I love to ______ (与他人分享) my creativity.78、What do we call a young female bear?A. CubB. KitC. PupD. Leveret答案:A79、What is the common name for H2O?A. OilB. JuiceC. WaterD. Soda答案:C80、填空题:We have a ______ in our backyard.81、听力题:The wind is ___ (strong/light).82、填空题:My teacher is __________ (鼓励的) during exams.83、听力题:His favorite movie is a ________.84、How many days are there in a week?A. 5B. 6C. 7D. 8答案:C. 785、填空题:The ________ was a famous trade route connecting Europe and Asia.86、What do we call the act of managing finances?A. BudgetingB. AccountingC. InvestingD. Planning答案:A87、填空题:A ____(pollutant) harms the environment.88、听力题:A chemical reaction can produce ______.89、选择题:What do we call the person who teaches us in school?A. DoctorB. TeacherC. EngineerD. Farmer90、Which animal has a pouch?A. DogB. CatC. KangarooD. Lion答案:C91、填空题:The __________ (历史的永恒) resonates with humanity.92、听力题:An earthquake can cause the ground to ______ violently.93、听力题:I have a _______ (goal) to achieve this year.94、听力题:I need to ______ my backpack before school. (pack)95、填空题:The __________ (历史的传说) captivates audiences.96、, I watch ________ (名词) about toys and learn new ways to play. This gives me many ________ (名词) ideas. 填空题:Sometime97、听力题:The ____ is known for its ability to leap high into the air.98、What is the name of the famous scientist who developed the theory of evolution?A. Charles DarwinB. Gregor MendelC. Louis PasteurD. Albert Einstein答案:A99、填空题:Creating a compost system can help recycle kitchen ______ into nutrient-rich soil. (创建堆肥系统可以将厨房废物回收利用成营养丰富的土壤。

高中英语阶段测试同步训练试题1304

高中英语阶段测试同步训练试题1304

高中英语阶段测试同步训练试题2019.101,Life is difficult. It is a great truth because once we truly understand and accept it, then life is no longer difficult.Most do not fully see this truth. Instead they complain about their problems and difficulties as if life should be easy. It seems to them that their difficulties represent a special kind of suffering especially forced upon them or else upon their families, their class, or even their nation.What makes life difficult is that the process of facing and solving problems is a painful one. Problems, depending on their nature, cause in us soreness or loneliness or regret or anger or fear. These are uncomfortable feelings, often as any kind of physical pain. And since life causes an endless series of problems, life is always difficult and is full of pain as well as joy.Yet, it is in this whole process of solving problems that life has its meaning.Problems are the serious test that tells success from failure. When we desire to encourage the growth of the human spirit, we encourage the human ability to solve problems, just as in school we set problems for our children to solve, it is through the pain of meeting and working out problems that we learn. As Benjamin Franklin said, “Those things that hurt instruct. ”It is for thisreason that wise people learn not to fear but to welcome the pain of problems.1. From the passage, it can be inferred that_______.A. nobody has problemsB. we become stronger by facing and solving the problems of lifeC. life is difficult because our problems bring us painD. people like to complain about their problems2. The writer probably used just one short sentence in the first paragraph to _______.A. save spaceB. persuade readersC. make readers laughD. get readers’ attention3. According to the passage, we give school children difficult problems to solve in order to ______.A. encourage them to learnB. teach them to fear the pain of solving problemsC. help them learn to deal with painD. teach them how to respect for problems4. The saying from Benjamin Franklin “Those things that hurt instruct” suggests that _______.A. we do not learn from experienceB. we do not learn when we are in painC. pain teaches us important lessonsD. pain cannot be avoided5.The underlined word in Paragraph 3 means _________.A. happinessB. pleasureC. sadnessD. despair2,_____ 1. You run a billboard advertising business you inherited(继承) from your father, and you are looking to expand in new directions. What do you do?_____ 2. You are a successful talk-show host, and have just achieved national recognition(认可). You want more control over your show, and a greater share of its profits. What do you do? _____3. You are still in college, but together with a friend you have established a software company that deals with major corporations. What do you do?_____ 4. You are a successful business analyst(分析师), and come to think that the mail-order business model could be adapted to online book sales. What do you do?_____ 5. You own several highly profitable waste-collection routes. The government has recently issued the Solid Waste Disposal Act, increasing standards of hygiene(卫生)in waste disposal. What do you do?A In 1968, H. Wayne Huizenga teamed with a partner to create a nationwide company for waste collection, a business traditionally made up of small, local companies. The new company, Waste Management, Inc., became the foundation of his fortune.B While attending Harvard University in 1975, Bill Gates teamedwith Paul Allen to develop a version of the BASIC programming language for the Altair 8800, the first personal computer. They licensed the software to the manufacturer of the Altair and formed Microsoft (originally Micro-soft) to develop versions of BASIC for other computer companies. Gates decided to drop out(退学) of Harvard in his junior year to devote his time to Microsoft.C In 1963, Ted Turner took over his family billboard-advertising business. In 1970 he bought a failing UHF(ultrahigh frequency) television station in Atlanta, Georgia, and by 1975 Turner had transformed it into the first “superstation”-WTBS, by transmitting(传送) low-cost sports and entertainment programs via satellite to cable systems throughout the country.D In 1986, Oprah Winfrey formed Harpo Productions to produce her own show and other projects. With distribution rights(销售权)to her shows, Winfrey used profits to expand her business activities. By 1998 Winfrey was worth $675 million.E Microsoft founder Bill Gates planned to give away almost all of his vast fortune, largely to the cause of global health. Having already the Bill & Melinda Gates Foundation with $ 24 billion to address global health issues, Gates said that eventually his entire fortune would be put towards the cause except “a few percent left for the kids.”F Amazon. com founder Jeff Bezos grew interested in onlineretailing(零售业) in 1994 while working as a business analyst in New York City. After researching the success of differentmail-order companies Bezos decided that books were the perfect product to see via the Internet. That year he left New York to establish his new company in Seattle, chosen for its being near to major book wholesalers and the advanced high-tech industry. In July 1995 Amazon. com developed its Web site, and has since expanded to offer many other retail products in addition to books.3,_____ 1. You run a billboard advertising business you inherited(继承) from your father, and you are looking to expand in new directions. What do you do?_____ 2. You are a successful talk-show host, and have just achieved national recognition(认可). You want more control over your show, and a greater share of its profits. What do you do? _____3. You are still in college, but together with a friend you have established a software company that deals with major corporations. What do you do?_____ 4. You are a successful business analyst(分析师), and come to think that the mail-order business model could be adapted to online book sales. What do you do?_____ 5. You own several highly profitable waste-collection routes. The government has recently issued the Solid Waste Disposal Act, increasing standards of hygiene(卫生)in waste disposal. What do you do?A In 1968, H. Wayne Huizenga teamed with a partner to create anationwide company for waste collection, a business traditionally made up of small, local companies. The new company, Waste Management, Inc., became the foundation of his fortune.B While attending Harvard University in 1975, Bill Gates teamed with Paul Allen to develop a version of the BASIC programming language for the Altair 8800, the first personal computer. They licensed the software to the manufacturer of the Altair and formed Microsoft (originally Micro-soft) to develop versions of BASIC for other computer companies. Gates decided to drop out(退学) of Harvard in his junior year to devote his time to Microsoft.C In 1963, Ted Turner took over his family billboard-advertising business. In 1970 he bought a failing UHF(ultrahigh frequency) television station in Atlanta, Georgia, and by 1975 Turner had transformed it into the first “superstation”-WTBS, by transmitting(传送) low-cost sports and entertainment programs via satellite to cable systems throughout the country.D In 1986, Oprah Winfrey formed Harpo Productions to produce her own show and other projects. With distribution rights(销售权)to her shows, Winfrey used profits to expand her business activities. By 1998 Winfrey was worth $675 million.E Microsoft founder Bill Gates planned to give away almost all of his vast fortune, largely to the cause of global health. Having already the Bill & Melinda Gates Foundation with $ 24 billion toaddress global health issues, Gates said that eventually hisentire fortune would be put towards the cause except “a few percentleft for the kids.”F Amazon. com founder Jeff Bezos grew interested in online retailing(零售业) in 1994 while working as a business analyst in New York City. After researching the success of differentmail-order companies Bezos decided that books were the perfect product to see via the Internet. That year he left New York to establish his new company in Seattle, chosen for its being near to major book wholesalers and the advanced high-tech industry. In July 1995 Amazon. com developed its Web site, and has since expanded to offer many other retail products in addition to books. 4,Reading: Read and then and five questions on thepassage, using orParents should stop blaming themselves because there’s not a lotthey can do about it. I mean the teenager (十几岁的孩子) problem.Whatever you do or however you choose to deal with it, at certaintimes a wonderful, reasonable and helpful child will turn intoa terrible animal.I’ve seen friends deal with it in all kinds of different ways. Onestrict mother insisted that her son, right from a child, shouldstand up whenever anyone entered the room, open doors and shakehands like a gentleman. I saw him last week when I calledround.Sprawling himself (懒散地躺) on the sofa in full length,he made no attempt to turn off the loud TV he was watching as Iwalked in, and his greeting was no more than a quick glance atme. His mother was ashamed.“I don't know what to do with him these days,” she said.“He’s forgotten all the manners we taught him.”He hasn’t forgotten them. He’s just decided that he’ s not going to use them. She confessed (坦白) that she would like to come up behind him and throw him down from the sofa onto the floor. Another good friend of mine let her two daughters climb all over the furniture, reach across the table, stare at me and say, “I don’t like your dress; it’s ugly.”One of the daughters has recently been driven out of school. The other has left home.“Where did we go wrong?” her parents are now very sad.Probably nowhere much. At least, no more than the rest of that unfortunate race, parents.1.Question_____________________________________________________ _____Answer_______________________________________________________ ______2.Question_____________________________________________________ _____Answer_______________________________________________________ ______3.Question__________________________________________________________Answer_______________________________________________________ ______4.Question_____________________________________________________ _____Answer_______________________________________________________ ______5.Question_____________________________________________________ _____Answer_______________________________________________________ ______试题答案1, 1-5 BDCCC2, CDBFA3, CDBFA4, Reading: Read and then and five questions on the passage, using or。

小学上册第12次英语第五单元期末试卷

小学上册第12次英语第五单元期末试卷

小学上册英语第五单元期末试卷英语试题一、综合题(本题有100小题,每小题1分,共100分.每小题不选、错误,均不给分)1.What is the main ingredient in cereal?A. OatsB. RiceC. WheatD. CornA2.The Great Lakes are located in __________.3.The _______ (小长颈鹿) stretches its neck to eat leaves.4.How many legs does an octopus have?A. SixB. EightC. TenD. Twelve5.I want to learn how to ________ (做衣服).6.What is 3 + 5?A. 6B. 7C. 8D. 97.The chicken lays _______ (蛋) in the coop.8.The chemical symbol for gold is ______.9.My _____ (妹妹) likes to draw.10.Elements are arranged in the periodic table by their ________ number.11.I enjoy spending time with my ______ during holidays.12.Which gas is most abundant in the Earth's atmosphere?A. OxygenB. NitrogenC. Carbon DioxideD. HydrogenB13.We are going to a ______ (circus) next month.14.We visit the ______ (历史博物馆) to learn about ancient cultures.15.The chemical symbol for copper is _______.16.My sister enjoys __________ (打篮球) with friends.17.What do we call a shape with four equal sides and angles?A. RectangleB. SquareC. CircleD. Triangle18.My best friend and I have matching _________ (玩具).19.What is the name of the famous rock formation located in Australia?A. Ayers RockB. StonehengeC. UluruD. Mount RushmoreC20.The ________ (puzzle) is challenging but fun.21.The __________ (城市发展) impacts local communities.22.古代的________ (architecture) 在意大利和希腊相当有名。

国家开放大学《管理英语3》形考任务1-8参考答案(2022春更新)

国家开放大学《管理英语3》形考任务1-8参考答案(2022春更新)

国家开放大学《管理英语3》形考任务1-8参考答案形考任务1一、选择填空,从每题选项中选出一个能填入空白处的最佳选项(每题10分)。

1、—______________—We have three major divisions: Operations, Sales and Marketing, Finance and Administration.A. How many departments do we have?B. Which division are you in?C. Which department shows the best?2、—I suppose there'll be a lot of arguments.—____________A. I should imagine so.B. No problem.C. That's a good idea.3、A number of boys _______absent some time during the term.A. have beenB. has beenC. will4、He will write to me as soon as he ______ home.A. will have returnedB. returnsC. will return5、This is the man ___ last night.A. whom I saw himB. whom I sawC. who I saw him6、—_______________—No, sorry, I didn't know the rule about punching in.A. Are you late this morning, Wendy?B. Didn't you punch out this morning, Wendy?C. Didn't you punch in this morning, Wendy?7、—I wish you success in your career.—_________________A. Go ahead.B. It doesn't matter.C. The same to you.8、I am _______your early coming.A. looking forward toB. looking forwardC. look forward to9、The programme gives students the _______to learn more about global warming.A. successB. ambitionC. opportunity10、The key________successful implementation is clearly communicating the strategy to the whole company.A. toB. inC. of11、—I'm leaving for Shanghai tomorrow.—__________________A. See you later.B. Have a pleasant trip!C. Let's go out for a drink.12、—Who should be responsible for the accident?—The boss, not the workers. They just carried out the order_______.A. as are toldB. as toldC. as they told13、Leave the reference books behind, _______you won't be able to think independently.A. orB. andC. so14、A bus driver ________the safety of his passengers.A. is responsible inB. is responsible forC. is responsible to15、My friend invited me ________the art club, and I accepted it with pleasure.A. joinB. to joinC. joining二、听力理解听对话录音,根据对话内容判断正误(每题10分)。

浙江省温州市十校联合体2012-2013学年高二英语上学期期末联考试题新人教版

浙江省温州市十校联合体2012-2013学年高二英语上学期期末联考试题新人教版

2012学年第一学期十校联合体高二期末联考英语试卷〔总分为120分,考试时间:100分钟〕第I卷〔共95分〕第一局部:听力〔共两节,总分为20分〕第一节〔共5小题,每一小题1分,总分为5分〕听下面5段对话。

每段对话后有一个小题,从题中所给的A、B、C三个选项中选出最优选项,并标在试卷的相应位置。

听完每段对话后,你都有l0秒钟的时间来回答有关小题和阅读下一小题。

每段对话仅读一遍。

1.What seems to be wrong with the woman’s car?A.One of the doors is broken.B.The door handles don’t work.C.The engine needs to be changed.2.Where are the speakers most probably?A.In a coffee bar.B. In a shop.C. In a street.3.What is the man doing?A.Making a request.B. Making a suggestion.C. Making a complaint.4.When should they leave?A.7:40.B.7:15.C. 7:30.5.What does the man think of the film?A. Disappointing.B. Confusing.C. Enjoyable.第二节〔共15小题,每一小题1分,总分为15分〕听下面5段对话或独白。

每段对话或独白后有几个小题,从题中所给的A、B、C三个选项中选出最优选项,并标在试卷的相应位置。

听每段对话或独白前,你将有时间阅读各小题,每一小题5秒钟;听完后,各小题将给出5秒钟的作答时间。

每段对话或独白读两遍。

听下面一段对话,完成第6和第7题。

6. What are the speakers mainly talking about?A. A psychology class.B. Their homework.C. A scientific report.7. What does the woman think is easy?A. Preparing a survey questionnaire.B. Finding enough people.C. Analyzing the data.听下面一段对话,完成第8至第10题。

小学下册第2次英语第一单元期中试卷

小学下册第2次英语第一单元期中试卷

小学下册英语第一单元期中试卷考试时间:80分钟(总分:140)B卷考试人:_________题号一二三四五总分得分一、综合题(共计100题共100分)1. 听力题:A _______ is a type of reaction that absorbs energy.2. 填空题:Gold is a _______ metal that does not tarnish easily. (贵重)3. ts are adapted to survive in extremely ______ environments.(某些植物适应在极端环境中生存。

) 填空题:Some pla4. 选择题:What do we wear on our feet?A. SocksB. GlovesC. ShoesD. Hat5. 填空题:The first successful vaccine for rabies was developed by ______ (巴斯德).6. 选择题:Which instrument is used to measure temperature?A. BarometerB. ThermometerC. RulerD. Clock答案: B7. 听力题:The __________ is a large area of sand.8. 听力题:In a ______ change, the substance's identity does not change.The ______ (阳光充足的)地方是最适合植物生长的。

10. 听力题:The clock shows ______ o'clock. (three)11. 填空题:The _____ (植物分类学) helps identify and classify species.12. 选择题:What do we call the part of the brain that controls thinking?A. CerebellumB. CerebrumC. BrainstemD. Cortex答案:B13. 填空题:My favorite sport is ______ (乒乓球).14. 选择题:What is the name of the phenomenon where light is bent by gravity?A. Gravitational LensingB. Light BendingC. Cosmic CurvatureD. Space-Time Distortion15. 填空题:The __________ (滑雪) resort is popular in winter.16. 填空题:Antarctica is known for its ________ (南极以其________) and extreme cold.17. 填空题:The _______ (The Opium Wars) were conflicts between China and Britain.18. ta Stone helped scholars understand ______ (古埃及) writing. 填空题:The Rose19. 听力题:A ______ has a symbiotic relationship with flowers.20. 填空题:I enjoy baking cakes with my mom for special ________ (庆祝活动).The ancient Greeks were known for their ________ sculptures.22. 填空题:A _____ (城市绿化) initiative can improve living conditions.23. 听力题:A _______ is a chemical process involving enzymes.24. 听力题:The _____ (tree/house) is tall.25. 选择题:What is the term for the area around a star where planets can potentially support life?A. Goldilocks ZoneB. Habitable ZoneC. Safe ZoneD. Life Zone26. 填空题:My sister is skilled at ____.27. 听力题:The chemical symbol for selenium is ______.28. 选择题:What is the name of the famous mouse created by Walt Disney?A. Donald DuckB. GoofyC. Mickey MouseD. Pluto29. 选择题:What is the name of the fairy tale character who lost her glass slipper?A. Snow WhiteB. CinderellaC. RapunzelD. Sleeping Beauty答案:B30. 听力题:She wants to be a ________.31. 听力题:The ______ is often seen in parks.My brother often plays _______ (名词) with his friends. 他觉得这个很 _______ (形容词).33. 选择题:How many continents are there?A. 5B. 6C. 7D. 834. 填空题:The _______ (猪) snorts loudly.35. 听力题:The _____ (游泳) is refreshing.36. 填空题:The __________ (种植计划) is essential for successful gardening.37. 听力题:A ______ is a type of fish that can change color.38. 填空题:The _______ (虎) is a powerful hunter.39. 填空题:My favorite subject is __________. (数学)40. 听力题:The _____ (kite) is flying high.41. 填空题:The flamingo has long _______ (腿).42. 听力题:We have ______ (math) class at o'clock.43. 听力题:She is wearing a ________ dress.44. 听力题:The book is on the ___ (shelf/table).The chemical symbol for iodine is ______.46. 听力题:I love to drink ___. (chocolate milk)47. 填空题:I enjoy visiting the ________ (科技馆) to learn new things.48. 填空题:A _____ (stream) nourishes the surrounding plants.49. 填空题:The flowers in the garden are very _______ and bright.50. 填空题:My favorite time of year is ______.51. 填空题:A kitten purrs when it is ______ (开心).52. 听力题:A _______ measures the amount of energy consumed.53. 填空题:A _____ (蛇) often hides in tall grass.54. 选择题:What do you call a person who plays a string instrument?A. ViolinistB. CellistC. BassistD. All of the above答案:D55. 听力题:The ice cream is ______ on a hot day. (refreshing)56. 选择题:What is the main purpose of a compass?A. To tell timeB. To find directionC. To measure distanceD. To calculate weight答案:BShe is _____ (reading/writing) a story.58. 填空题:The _____ (植物多样性) is crucial for ecosystem resilience.59. 填空题:The ______ (青蛙) can leap great distances with its strong legs.60. 填空题:The ________ (电力供应) is important for development.61. 填空题:The ______ (生长速度) can be affected by temperature.62. 选择题:What is the opposite of light?A. HeavyB. DarkC. BrightD. Soft63. 填空题:I like _______ (玩游戏) on my computer.64. 填空题:The _____ (温室) allows for year-round gardening.65. 选择题:What do we call the study of the Earth's physical structure?A. GeographyB. GeologyC. BiologyD. Meteorology答案:B66. 填空题:I enjoy playing _________ (视频游戏) with my friends online.67. 选择题:What do we call the act of practicing a skill?A. TrainingB. RehearsingC. CoachingD. Drilling答案:A68. 听力题:The ____ is known for its ability to leap great distances.69. 选择题:What is the name of the famous wizarding school in Harry Potter?A. HogwartsB. DurmstrangC. BeauxbatonsD. Ilvermorny70. 选择题:What is the opposite of "big"?A. LargeB. SmallC. HugeD. Giant答案: B71. 填空题:I planted a _____ (树) in my yard.72. 填空题:My favorite subject is _______ (英语).73. 填空题:A ____(community coalition) unites diverse stakeholders.74. 填空题:My favorite food is _______.75. 听力题:The reaction of acids with metals is often used to produce ______.76. 填空题:My dad loves __________ (参加比赛).77. 填空题:I can combine different ________ (玩具类型) to create something new.78. 填空题:The frog's powerful legs allow it to leap great ______ (距离).The man is very ________.80. 听力题:The _______ of light can create various effects in technology.81. 选择题:How many sides does a triangle have?A. TwoB. ThreeC. FourD. Five82. 听力题:The symbol for osmium is _______.83. 听力题:A _______ is a physical change that involves a change in state.84. 填空题:I like to color with my _____ (彩色铅笔).85. 填空题:My friend is a great __________ (听众).86. 选择题:What do we call the part of the plant that grows above the ground?A. RootB. StemC. LeafD. Flower答案: B87. 填空题:A gecko can climb ______ (墙).88. 填空题:My family loves to __________ on weekends. (爬山)89. 选择题:What color is the sky on a clear day?A. GreenB. BlueC. YellowD. Red答案:BWhich instrument is played with a bow?A. TrumpetB. FluteC. ViolinD. Drums91. 听力题:The chemical formula for copper sulfate is _______.92. 听力题:The ______ helps us understand the world.93. 选择题:What is the main ingredient in pudding?A. WaterB. MilkC. SugarD. Gelatin答案:B94. 听力题:A __________ is a reaction that produces solid precipitates.95. 听力题:The wind is very ___ (strong/light).96. 填空题:The ancient Romans established ________ to govern their territories.97. 选择题:What is the capital of Panama?A. Panama CityB. ColonC. DavidD. Santiago答案:A98. 听力题:A __________ is a mixture that does not settle.99. 填空题:People often plant flowers for __________ (美观).100. 选择题:What do we call the smallest particle of an element?A. AtomB. MoleculeC. CompoundD. Ion。

Quality of medicines questions and answers (中英文)

Quality of medicines questions and answers (中英文)

Quality of medicines questions and answers These questions and answers address a number of questions that have been brought to the attention of the Joint Committee for Medicinal Products for Human Use / Committee for Medicinal Products for Veterinary Use Quality Working Party (QWP) by marketing-authorisation holders (MAHs) or European Economic Area (EEA) competent authorities, on matters related to the quality of medicines. They have been developed and are maintained by the QWP.They provide the EEA's harmonised position on issues that can be subject to different interpretation or require clarification, typically arising from discussions or correspondence during assessment procedures.If a question is not addressed, marketing-authorisation holders are encouraged to contact the European Medicines Agency for further information atqwp@ema.europa.eu.These questions have been produced to provide clarification or additional information, and should be read in conjunction with the European Pharmacopoeia, quality guidelines and other guidance documents.Key:∙H: applicable to medicinal products for human use∙V: applicable to veterinary medicinal productsQuality of medicines questions and answers: Part 1:Active Substance - Active-substance-master-file procedure1.Can a mixture of an active substance with an excipient be submitted through anactive-substance-master-file (ASMF) procedure? H+V August 2007.No. A mixture of an active substance with an excipient cannot be submitted through an ASMF procedure.The blending of an active substance and an excipient is considered as the first step in the manufacture of the medicinal product, and therefore does not fall under the definition of an active substance.The only exceptions can be made where the active substance cannot exist on its own,for example, due to insufficient stability without a stabilising agent, or in the case of herbal dry extracts if it is not possible to produce a solid extract without excipients. Active substance - Declaration by the qualified person on the good-manufacturing-practice status of the active substance manufacturer1.The notice to applicants requires the submission of a declaration signed by thequalified person that the active substance used is manufactured in accordance with good manufacturing practice. The active substance in my product is widely used, but not normally as a pharmaceutical active substance, and I am having some difficulty in confirming compliance. What should I do to furnish the required declaration? H+V September 2008Full compliance with good manufacturing practice (GMP) for finished products and active substances is a legal obligation for manufacturing-authorisation holders. It is recognised that for a small number of medicinal products the primary use of the active substance is not in a medicinal product and the producer may therefore not be aiming to meet the specific requirements of pharmaceutical customers that represent an insignificant volume of business. Alternative sources should normally be sought but in exceptional circumstances the manufacturing-authorisation holder should assess and document to which extent GMP is complied with and provide a risk-based justification for the acceptance of any derogation. The declaration provided by the qualified person should set out in detail the basis for declaring that the standards applied provide the same level of assurance as GMP. The European Medicines Agency will collect experience with this approach which can be used as a basis for discussion on related amendments to guidelines in the future.Active Substance - Good-manufacturing-practice compliance for sterilisation of an active substance1.What kind of good-manufacturing-practice documentation is needed for an activesubstance manufacturer who performs sterilisation of an active substance? H+V July 2010The good-manufacturing-practice (GMP) basic requirements for active substances used as starting materials (European Union (EU) GMP guide part II) only applies to the manufacture of sterile active substances up to the point immediately prior to the active substance being rendered sterile. The sterilisation and aseptic processing of sterile active substances are not covered by this guideline and shall be performed in accordance with GMP for medicinal products (Commission Directive 2003/94/EC; as interpreted in the basic requirements for medicinal products including annex 1 of theEU GMP Guide part I). This implies that for any active-substance manufacturer who performs sterilisation and subsequent aseptic handling of the active substance, a valid manufacturing authorisation or GMP certificate from an EEA authority or from an authority of countries where mutual recognition or other Community arrangements apply has to be submitted.Also, the active-substance manufacturer has to submit data on the sterilisation process of the active substance (including validation data) to the marketing-authorisation applicant or holder for inclusion in the dossier submitted for the finished product and approval by the licensing authority or authorities.Active Substance - Starting materials of herbal origin1.How should the quality of a starting material of herbal origin be controlled when itis used to manufacture a semi-synthetic active substance? H+V February 2012 There are several types of starting materials of herbal origin used to manufacture semi-synthetic active substances:herbal drugs;herbal preparations (typically extracts);isolated plant constituents (no additional synthetic steps).Starting materials of herbal origin should be characterised to ascertain their suitability and a contaminant profile should be established and submitted, taking into consideration the number of chemical steps between the starting material and the semi-synthetic active substance.In all cases, the scientific name (genus, species, variety and author) of the plant and plant part used should be specified. If the starting material is an extract or an isolated constituent, the extraction solvent and strength (e.g. ethanol 50% v/v) used for the first extraction from the herbal drug should be specified as well.The quality of the starting material of herbal origin should follow the principles set out in the European Pharmacopoeia monographs on herbal drugs, herbal drug preparations, extracts and essential oils, as applicable: the potential presence of foreign matter, pesticides, microbiological contamination, total ash, heavy metals, aflatoxins, ochratoxin A, radioactive contamination, residual solvents, and other relevant impurities should be discussed.Potential contaminants that may be carried through the extraction and purification processes should be fully addressed taking into account the production of the herbal drug, and the subsequent extraction and purification processes.The specification for the starting material of herbal origin should be fully justified by the applicant and should include suitable tests for identity, assay, impurities and potential contaminants.Compliance with the guideline on good agricultural and collection practice (GACP) is not mandatory in the steps prior to the starting material of a semi-synthetic active substance, since it applies to herbal medicinal products and traditional herbal medicinal products. However, information on the geographical origin, collection or cultivation, harvesting, and post-harvest treatments (possible pesticides and fumigants used and possible radioactive contamination) could justify limited testing for (possible) contaminants.Data submission1.Is the submission of data regarding manufacturing process validation, analyticalvalidation, and stability studies, produced only by the developer of the product sufficient? Does it make any difference if the developer of the product is presented as one of the product manufacturers or not? H+V July 2008These questions and answers only concern products that are oral solid dosage forms manufactured by standard manufacturing methods. The new product has the same formula and manufacturing method of the developed product.Provided that the formula, manufacturing process, analytical methods and packaging materials are the same, data originating from the developer of the product is normally sufficient. As regards manufacturing process validation, the marketing authorisation holder, according to the guideline on process validation, must submit with the new application the process validation scheme and the commitment to carry out process validation and initiate stability studies along with the batch analysis for production scale batches for the new manufacturing site. This is irrespective of whether the product developer is one of the manufacturing sites of the new product or not.2.Who is responsible to verify the production scale validation data when this isavailable? H+V July 2008These questions and answers only concern products that are oral solid dosage forms manufactured by standard manufacturing methods. The new product has the same formula and manufacturing method of the developed product.According to the guideline on process validation, "the results can be subsequently verified by supervising authority according to national procedure.” Depending on the product and the concerns that may arise, in some countries this may be dealt with as a post-authorisation commitment or it may be brought to the attention of good-manufacturing-practice inspectors to be checked during their next inspection. The marketing-authorisation holder is usually not expected to present these data with the new application, unless it is requested by the licensing authorities.3. Can the test product of a bioequivalence study be produced by the developer, irrespective of whether that developer is one of the manufacturing sites of the new product? H+V July 2008These questions and answers only concern products that are oral solid dosage forms manufactured by standard manufacturing methods. The newproduct has the same formula and manufacturing method of the developed product. The product used in the bioequivalence study must be representative of the industrial scale product to be marketed.A bioequivalence study conducted using a test product produced by the developer is acceptable if the developer is also one of the manufacturers of the new product.If the developer is not one of the manufacturers of the new product, it has to be demonstrated that the bioequivalence batch is representative of the industrial scale product to be marketed.For this the following applies:The developer product and the new product must have identical formula, specifications, manufacturing process and equipment;The active substance supplier is the same or it is ensured that characteristics of the active substance that may have an impact on the bioavailability are identical;The excipients characteristics which may have an impact on the bioavailability of the active substance are identical;The dissolution profiles of batches produced by the developer (including the biobatch) and the product from the new manufacturer (at least pilot batches) must be similar;Comparative pilot batch analysis between the developer product (including the biobatch) and the new manufacturer product must be presented.4. Is there any requirement for the marketing-authorisation holder to submit any kind of proof (e.g. statement or contract) that it has obtained the dossier from the developer legally? H+V July 2008These questions and answers only concern products that are oral solid dosage forms manufactured by standard manufacturing methods. The new product has the same formula and manufacturing method of the developed product. No such proof is necessary to be presented in the application dossier.European Pharmacopeia (Ph. Eur.) - Harmonised Ph. Eur. Chapters 2.6.12, 2.6.13 and 5.1.41.How should any update to the microbial quality control of a finished product,specifically linked to the update to the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) harmonised Ph. Eur. methods (2.6.12 and 2.6.13) and limits (5.1.4) be achieved? H+V February 2012Any changes to implement the harmonised methods (2.6.12 and 2.6.13) should be submitted under change code B.II.d.2.a (type IA).Any changes to implement the harmonised limits (5.1.4) should be submitted asfollows:Changes to the limits – B.II.d.1.a (type IA), but only in the following situations:The currently registered microbial control limits (present situation) are totally in line with the pre-January 2008 (non-harmonised) situation and did not include any additional specified controls over and above the Pharmacopoeia requirements for that particular dosage form. In addition, the proposed controls are totally in line with the harmonised monograph.If for any reason these criteria are not met, a type IB variation (B.II.d.1.z) should be submitted.In accordance with current requirements, any changes should be clearly identified (present / proposed) in the variation submission and the affected parts of the marketing-authorisation dossier should be appropriately updated, including a description of how the method is applied to the specific product.Please note that this advice supersedes the questions and answers dated August 2007, which are now out of date.European Pharmacopeia - Monograph on tablets1.How should industry apply the revised test subdivision of tablets in the EuropeanPharmacopeia monograph on tablets? H+V October 2006The requirements of the European Pharmacopoeia (Ph. Eur.) general monograph on tablets for tablets with one or more breaklines have been revised as of 1 July 2006. The previous version of the monograph, which has been in force since April 2002, requested compliance with either test A (uniformity of content of single-dose preparations) or the test for uniformity of mass of single-dose preparations. It did not, however, give any information on how to select the parts to be tested. Supplement 5.5 now provides background information on the use of breakmarks and describes the sampling procedure and the number of tablet parts to be tested in detail. As a test procedure, it prescribes determining uniformity of mass, while setting the somewhat wider acceptance criteria of the test of content uniformity, namely 85 - 115% (in this case of the average mass).According to Directives 2001/83/EC and 2001/82/EC, the monographs of the Ph. Eur. are the official standards of appropriate quality in the marketing authorisation procedures. In the pharmacopoeia it is also stated that a preparation must comply with the monograph throughout its period of validity.As the revised text defines lesser requirements with wider acceptance criteria than the previous version (see above), a decision has been taken by the regulatory authorities of the European Union (EU) that the revised test on subdivision of tablets is to be applied to all new applications for marketing authorisations as well as all existingproducts. It is acknowledged, however, that the new test will not have been applied to products which are in the final stages of their development. In order not to delay any immediate applications and in line with the period of time defined in the variations regulation, a transitional period of 6 months following the coming into force of Ph. Eur. 5.5 has been defined, in which the EU regulatory authorities will accept submission of results which have been generated using the previous version of the monograph.As the requirements on subdivision of tablets are listed in the production section of the general monograph on tablets, it will normally be sufficient to perform the test only in the framework of pharmaceutical development. There is no need to include the test in the release specification. However, in situations where there is a significant change in tablet hardness during storage, it may be necessary to repeat the test at the end of shelf-life in order to ensure that the scorability has not changed as a function of hardness.European Pharmacopeia (Ph. Eur.) - Harmonised chapter uniformity of dosage unitsBackground. H+V June 2012Between 2004 and 2008, various questions and answers have been published on this website to clarify how the harmonised European Pharmacopoeia (Ph. Eur.) chapter on uniformity of dosage units (2.9.40) and the general chapters on uniformity of mass of single-dose preparations (2.9.5) and uniformity of content of single-dose preparations (2.9.6) should be applied in the European Union (EU), also in view of the compliance objection made by the United States Food and Drug Administration to the USP on the 2% relative-standard-deviation clause in general chapter 2.9.40. This matter has been recently reviewed by EU regulators and the resulting agreed position is presented in the following questions and answers, which replace the previous questions and answers 1 and 4 published on the same subject in 2004 and 2006, which have now been deleted from the website.1.How should industry demonstrate compliance with the European Pharmacopoeiawith regard to uniformity of dosage units? H+V June 2012Medicinal products marketed in the European Union need to be in compliance with the relevant requirements in the European Pharmacopoeia (Ph. Eur.).From a pharmaceutical quality point of view, the approach taken in the harmonised general chapter on uniformity of dosage units (2.9.40) is considered equivalent to what was previously required in the Ph. Eur. through the general chapters on uniformity of mass of single-dose preparations (2.9.5) and uniformity of content of single-dose preparations (2.9.6). These general chapters, 2.9.5 and 2.9.6, are still included in the current version of the Ph. Eur.Taking this into account, the decision on what approach to take is left to the applicant. Application of either the Ph. Eur. harmonised general chapter on uniformity of dosage units (2.9.40) or the Ph. Eur. general chapters on uniformity of mass of single-dose preparations (2.9.5) and uniformity of content of single-dose preparations (2.9.6) are both considered acceptable options to demonstrate compliance with the Ph. Eur. with regard to uniformity of dosage units.Please note that this advice supersedes the previous questions and answers 1 and 4 published on the same subject in 2004 and 2006. The remaining previously published questions and answers on the use of the general chapter 2.9.40 (former questions and answers 2, 3, 5 and 6) are still valid and remain published as questions and answers 2 to 5.2. How should the new text be interpreted, in particular in relation to testing frequency (routine test / skip test / test on validation batches only)? H+V March 2006 Where a dosage form monograph in the European Pharmacopoeia refers to this general chapter, the product should comply. This is normally verified by routine testing unless otherwise justified and authorised.3. How can the text be interpreted in light of the compliance objection made by the Food and Drug Administration to the United States Pharmacopeia on the 2% relative standard deviation clause? H+V March 2006The harmonised text is included in the European Pharmacopoeia and the 2% clause will thus be valid in the European Union. This will not be dependent on the final outcome of the discussion between the Food and Drug Administration and the United States Pharmacopeia.4. When can the requirements in the harmonised European Pharmacopoiea general chapter on uniformity of dosage units (2.9.40) for mass variation, rather than content uniformity, be applied with reference to a relative standard deviation (RSD) of not more than 2%? Is it sufficient to determine the RSD on for example 3 validation batches? H+V July 2008It is the opinion of the Quality Working Party that the requirement in the harmonised chapter 2.9.40 regarding the 2% relative-standard-deviation clause represents minimum requirements. The use of this clause should be based on sufficient experience. Normally, results from 3 validation batches are not sufficient. It is rather to be used post-approval when more extensive production experience is gained.5. What is meant by single component and multiple component in the harmonised chapter 2.9.40? H+V July 2008'Single component' means one active substance with no excipient. 'Multiple component' could mean 'at least 2 active substances' or 'at least 1 active substance and at least one excipient'; both cases are valid.Impurities - Calculation of thresholds for impurities1.What is the basis for the calculation of thresholds to set limits for impurities in thefinished product specification? H July 2009The calculated thresholds should be based on the highest maximum daily dose of the respective active substance in authorised medicinal products. The threshold for impurities should be the same for all strengths.The same rule applies for combination drugs; the highest possible combined strength should be used for setting the thresholds.The maximum daily dose used for threshold calculation should be the same for a given active substance irrespective of the medicinal product.Impurities - Harmonisation of policies on setting specifications for potentially genotoxic impurities, heavy-metal-catalyst residues and class-1 solvent residues1.What is a reasonable policy for setting specifications for potentially genotoxicimpurities which are theoretical or actual impurities in a drug substance manufacturing process? H June 2012Different possible scenarios can be identified and the applicable policies to be applied for each of them are described below:Example 1 – A potential genotoxic impurityThe definition for a potential genotoxic impurity is derived from the definition for 'potential impurity': an impurity that theoretically can arise during manufacture or storage. It may or may not actually appear in the (new) drug substance (ICH Q3A, glossary).If a potential genotoxic impurity is just a theoretical impurity i.e. based on theoretical considerations but not found in practice at any key stage in the manufacturing process as demonstrated by studies during development of the manufacture, the impurity does not need to be included in the drug substance specification or a specification of an intermediate.Example 2 – A (potentially) genotoxic impurity actually formed or introduced prior to the final step of the synthesisIf a (potentially) genotoxic impurity is formed or introduced in a step before the final synthesis step, it is considered possible to not include this impurity in the drug substance specification if it is controlled by a suitable limit in a synthesis intermediate and if it is unambiguously demonstrated by analysis results (use of spiking experiments are encouraged) that presence of this impurity does not exceed 30 % of the limit, derived either from threshold of toxicological concern (TTC) or otherwisedefined acceptable limit etc., in the drug substance.It is considered possible to apply skip testing if the level of the impurity in a synthesis intermediate does not exceed 30% of the limit, derived from either TTC or otherwise defined acceptable limit etc, in the intermediate. Data should be presented for at least 6 consecutive pilot scale or 3 consecutive production scale batches. If this condition is not fulfilled, a routine test in the intermediate is needed. If the impurity exceeds 30% of the limit, derived either from TTC or otherwise defined acceptable limit etc., in the drug substance the impurity has to be included in the drug substance specification and the test has to be carried out on a routine basis.Should a genotoxic impurity not be controlled at the intermediate stage, then the scenario of example 3 applies.Example 3 - A (potentially) genotoxic impurity is formed or introduced in the last synthesis stepIf a (potentially) genotoxic impurity is formed or introduced in the final synthesis step, it should be included in the specifications. However, it is considered possible to apply skip testing if the level of the impurity does not exceed 30% of the limit, derived from either TTC or otherwise defined acceptable limit etc., in the drug substance. Data should be presented for at least 6 consecutive pilot scale or 3 consecutive production scale batches. If this condition is not fulfilled, a routine test in the drug substance specification is needed.Definitions:For the purpose of these questions and answers, the following definitions apply: Genotoxic impurity: an impurity that has been demonstrated to be genotoxic in an appropriate genotoxicity test model, e.g. bacterial gene mutation (Ames) test.Potentially genotoxic impurity: an impurity that shows (a) structural alert(s) for genotoxicity but that has not been tested in an experimental test model. Here potentially relates to genotoxicity, not to the presence or absence of this impurity.2.In order to harmonise the policies to be applied for setting specifications forgenotoxic impurities and heavy-metal-catalyst residues, what are reasonable policies to be applied when setting specifications for heavy-metal-catalyst residues? H June 2012In order to harmonise the policy for setting specifications for metal residues with that for setting specifications for genotoxic impurities, some clarifications of the interpretation of sections 4.5 and 4.6 of the heavy-metal-catalyst guideline (EMEA/CHMP/SWP/4446/2000) are given below.Since it is the class-1 metals that are the most toxic metals with permitted dailyexposures (PDEs) that approach the level of the threshold of toxicological concern (TTC) applied for genotoxic impurities, it seems reasonable that class-1 metals are the prime focus for harmonisation with the policy for genotoxic impurities while class-2 and 3 metals could be treated similarly but somewhat less strictly.Example 1 –A class-1 metal is not used or suspected to be present in a synthesis processMetals are not expected to be formed in synthesis processes. Only if deliberately introduced or suspected to be present for other reasons, residues of metals can be expected. If not used or suspected to be present, the metal does not need to be included in the drug substance specification or a specification of an intermediate.Example 2 –A class-1 metal is formed or introduced prior to the final step of the synthesisIf a class-1 metal is introduced in a step before the final synthesis step, it is considered possible to not include this metal in the drug substance specification if it is controlled by a suitable limit in a synthesis intermediate and if it is unambiguously demonstrated by analysis results that the presence of this metal does not exceed 30% of the guideline limit in the drug substance.It is considered possible to apply skip testing if the level of the class-1 metal in a synthesis intermediate does not exceed 30% of the guideline limit in the intermediate. Data should be presented for at least 6 consecutive pilot scale or 3 consecutive production scale batches. If this condition is not fulfilled, a routine test in the intermediate is needed. If the class-1 metal exceeds 30% of the guideline limit in the drug substance the impurity has to be included in the drug substance specification and the test has to be carried out on a routine basis.Should a class-1 metal not be controlled at the intermediate stage, then the scenario of example 3 applies.Example 3 – A class-1 metal is introduced in the last synthesis stepIf a class-1 metal is introduced in the final synthesis step, it should be included in the specifications. However, it is considered possible to apply skip testing if the level of the metal does not exceed 30% of the guideline limit in the drug substance. Data should be presented for at least 6 consecutive pilot scale or 3 consecutive production scale batches. If this condition is not fulfilled, a routine test in the drug substance specification is needed.3.In order to harmonise the policies to be applied for setting specifications forgenotoxic impurities and class-1 solvent residues, what are reasonable policies to be applied when setting specifications for class-1 solvent residues? H June 2012。

制药工程专业英语考试题目及答案

制药工程专业英语考试题目及答案

专业英语考试内容:单词10分句子翻译24分根据课文回答问题24分英译汉药品说明书21分翻译汉译英摘要21分Unit 11 Tablet (The Pharmaceutical Tablets Dosage Form)药片(医药片剂剂型)Role in TherapyA: The oral route of drug admininistration is the most important method of administering drugs ofr systemic effects.Except in cases of Insulin therapy.the parenteral route is not routinely used for self-administration of medication.The topical route of administration has only recently been employed to deliver drugs to the body for systemic effects,with two classes of marketed products:Nitroglycerin for the treatmint of angina and scopolamine for the treatment of motion sickness.Other drugs are certain to follow,but the topical route of administration is limited in its ability to allow effective drug absorption for systemic drug action.A:口服给药是全身效应用药方法中最为重要的。

除了胰岛素治疗,非肠道药途径不常用在自我服药方面。

2023执业药师鸭题库

2023执业药师鸭题库

2023执业药师鸭题库英文回答:1. Introduction.The pharmacy profession is rapidly evolving, with new technologies and advancements emerging all the time. In order to keep up with these changes, it is important for pharmacists to stay up-to-date on the latest research and best practices. One way to do this is by taking part in continuing education (CE) programs.2. Benefits of CE for Pharmacists.CE programs can offer a number of benefits for pharmacists, including:Enhanced knowledge and skills: CE programs can help pharmacists expand their knowledge base and develop new skills. This can lead to improved patient care and betterjob performance.Increased confidence: By staying up-to-date on the latest research and best practices, pharmacists can feel more confident in their abilities to provide safe and effective medication therapy.Improved patient care: Pharmacists who participate in CE programs are more likely to provide high-quality patient care. This can lead to improved patient outcomes and reduced healthcare costs.Career advancement: CE can help pharmacists advance their careers by making them more competitive for promotions and leadership positions.3. Types of CE Programs.There are a variety of CE programs available to pharmacists, including:Live programs: Live programs are held in person andtypically involve lectures, workshops, and demonstrations.Online programs: Online programs are offered through the internet and allow pharmacists to learn at their own pace.Home study programs: Home study programs involve reading materials and completing assignments on your own time.Preceptorship programs: Preceptorship programs involve working with a more experienced pharmacist to gain hands-on experience.4. Choosing the Right CE Program.When choosing a CE program, it is important to consider your individual needs and learning preferences. Somefactors to consider include:The topic of the program.The format of the program.The cost of the program.The location of the program.The reputation of the program.5. Conclusion.CE is an essential part of the pharmacy profession. By participating in CE programs, pharmacists can stay up-to-date on the latest research and best practices, improve their knowledge and skills, and provide high-quality patient care.中文回答:1. 导言。

跨境电子商务英语--03--答案3.1

跨境电子商务英语--03--答案3.1

Part 3.1 Build Y our Online StoreWarming-up ActivitiesListening参考答案及译文:1.campaign译文:一次有效的营销活动能够提高页面访问量,并为店铺带来更多的顾客。

2.relations译文:我方乐意在互利的基础上与你方建立直接的业务关系。

3.quoted译文:你方所报价格偏髙,我方感到很遗憾。

4.counter译文:很抱歉,我方无法接受你方的还盘。

5.delivery译文:由于供货推迟,我方不得不取消订单,对此我们感到很遗憾。

New Core VocabulariesTask1 Translate the following sentences into English, using the expressions in Brackets.参考答案1. He was a man with considerable insight.2.Welcome to our online storefront.Task2 Match the English words in the left column with the English explanation in the right column.参考答案1.2.Task3 Translate the following sentences into English, using the expressions in Brackets.参考答案1. Complete the following sentences by translating the Chinese given in the brackets into English.参考答案1.the date of the negotiation译文:请再次确认谈判日期。

2.the time schedule of the next five days译文:我来这儿想征求一下您对以后五天日程安排的意见。

药学英语模拟试卷1

药学英语模拟试卷1

福建医科大学药学院2007级临药、药剂、药物分析《药学英语》试卷考试日期:2009年12月7日组别学号姓名0.5分,共10分)1. anesthetic2. route of administration3. parenteral4. decomposition5. capacity factor6. partition coefficient7. gradient elution8. pharmacodynamics9. cation exchange resins10. size-exclusion chromatography11. spectrophotometric detector12. diode array multi-wavelength detectors13. differential refractometer detectors14. fluorometric detectors15. linear dynamic range16. external standard method17. disintegration test18. simulated gastric juice19. labelled amount20. quality control二、将下列词译成英文(每题0.5分,共10分)1. 新陈代谢2. 受体3. 给药途径4. 溶解5. 校准6. 亲和力7. 平衡8. 基线9. 衍生物10. 等度11. 鉴定, 鉴别12. 专属性,特异性13. 精密度14. 准确性15. 稳定性16. 提出物17. 分析,试验18. 添加剂19. 利用20. 效力,效价三、判断题(True or False)(每题1分,共10分)1. Ordinary fire can also be thought of as a chemical reaction inwhich the fuel and the oxygen in the air react to form the products of combustion. 【】2. Nitrous oxide was soon put into general use in surgical operationsafter its discovery by Humphry Davy. 【】3. Chemistry plays such an important part in the life of modern manthat no one can well understand the world in which he liveswithout the proper knowledge of chemistry. 【】4. The introductory chemistry course should begin at a veryelementary level as most students have had almost no preparation at all in chemistry. 【】5. The appropriate experiments devised and performed before theconstruction of the model are essential to the success of the whole process of model building. 【】6. As a first step, college students in introductory chemistry coursesshould be ready to accept a concept, then they must understand it in physical terms. 【】7. People have been duplicating some of the natural chemicals orsometimes producing completely new ones since the dawn of human history. 【】8. We should not equate a naturally derived chemical with itssynthetic counterpart since the impurities present in a natural product are bound to be different from those in its synthetic counterpart. 【】9. Active ingredients used in foods, drugs, and cosmetics may causephysiological changes in or on the body when taken internally or applied externally, while inactive ingredients only function to facilitate the ultimate intake or utilization of the active ingredients.【】10.Food additives, most of which are natural products, are added tofoods either directly or indirectly for the purposes of improving nutritional value, enhancing quality, reducing wastage, etc.【】Translation)(每题2分,共10分) 1.毫无疑问,植物王国仍然拥有许多种具有医药价值的植物,这仍有待于人们的发现。

最新湖南成人教育学位英语模拟试题和答案解析(二)

最新湖南成人教育学位英语模拟试题和答案解析(二)

2015年湖南成人高等教育学士学位英语模拟试题和答案解析(二)【答案在最后】Part I Dialogue Communication ( 15 % )Directions:ln this section,you will read 15 short incompletedialoguesbetween two speakers, each followed by 4 choices marked A, B, C and D. Choose the answer that best suits the situation to complete the dialogue by marking the corresponding letter on the Answer Sheet with a single line through the center.1. Waiter: Welcome, sir. May I help you?Customer:—A. Thank you. I have eate n a lot of food.B. Yes, please. 1' d like a hamburger and a cup of coffee.C. Sorry. I don' t n eed your help, tha nk you.D. If you want to help me, I' 11 be glad to accept it.2. W : How did your in terview go?M:—A. A man ager in terviewed me.B. I couldn't feel better about it ! The questions were very fair, and I seemed to find an swers for all of them.C. I was fully con fide nt that I an swered all the questio ns to the n eeds of the in terviewer.D. I an swered all the questi ons of the in terviewer to his satisfacti on. But he may discrim in ate aga inst me.3. Speaker A: It' s won derful to hear that your book has bee n published.Speaker B 一A. Oh, it' s nothing special.B. It' s OK.C. I' m glad to hear you flatter.D. No. Not a big deal for that.4. W:How annoying! I can't figure out a solution to this problem. Can you help me?M:—A. Why don' t you do it yourself?B. OK. Though it' s bey ond me, let me try.C. You shouldn' t feel annoyed. After all, it' s your own problem.D. Well, I' m afraid I can' t at the mome nt.5.Speaker A: I was hop ing to get some bread from the bakery before it closes. SpeakerA. You' d better be quick. It will close at 7: 00.B. My watch says 6: 50, I' m afraid you' 11 be late. But don' t be frustrated.C. I don' t know whe n it closes.D. I' ve n ever bee n to that bakery.6. Tom: I see in the paper they' re sending more equipme nt to space. And we might have to live there someday.John._ ! I' m staying right here !A. Never IB. Not meC. No meD. None me7. Goodbye !_A. I am look ing forward to see ing you aga in.B. Take care.C. It' s such a short time meeting, please do not go.D. Pay me ano ther visit soon.8. Speaker A: Would you like ano ther piece of apple pie 苹果派)?Speaker B j_A. Don' t push me. I' ve hardly eate n on.B. Come on. I can' t man age it.C. No kidd in g. I can' t eat any more.D. No, tha nks. I' m on a diet.9. Mike: Can I get you a cup of coffee?Tom:_A. I don' t take sugar, tha nk you.B. That' s very nice of you.C. You can, please.D. Thank you for the coffee.10. Speaker A: Do you happe n to know what's on after the n ews?Speaker B_A. There is no importa nt n ews after that.B. I' m not in terested in the programs.C. It' s a docume ntary about ani mals.D. I hope to watch a movie after that.11. Speaker A: There seems to be something wrong with the air-conditioner in our apartme nt.Speaker B :A. I' m awfully sorry for that .I'll see to it fight away.B. I do beg your pard on for the inconvenien ce.C. I just don' t know how to apologize for it.D. It' s not my fault. I feel sorry for it.12. W: I do hope Peter do well in his studies this semester.M:_A. Yes. I hope so.B. Yes. Dear. But I am afraid the school is not nice eno ugh.C. Neither do I. I don' t think his words would be as good as gold.D. Yes. Although we believe our son is hon est, he may not work hard eno ugh as he says.13. M: That' s a beautiful dress you have on!W:_A. Actually, I don' t like it very much.B. Oh, tha nk you. I just got it yesterday.C. Yes, I thi nk so.D. No, it' s not that beautiful. Yours is better.14. Speaker A: If you like, I could help you paint刷油漆)the room tomorrow. SpeakerA. You don' t have to give me a hand.B. That would be too much bother, but tha nks any way.C. I' m OK. You should n't worry about that.D. Unfortun ately I feel un able to accept your offer.15. W: The experime nt has bee n completed, has n't it?M:_A. Yes. We n eed ano ther week to complete it.B. Yes. It has bee n completed beautifully.C. No. It was completed last week.D. No. I have no idea about it.Part I Reading Comprehension (30%)Directions: There are 3 passageSn this part. Eachpassageis followed by some questions or unfinished statements. For each of them there are four choices marked A, B, C and D. You should decide on the best choice and mark the corresponding letter on the Answer Sheet with a single line through the center.Passage 1Questions 1 to 5 are based on the following passage :Washi ngton Irvi ng was America' s first man of letters to be known intern ati on ally. His works were received enthusiastically both in England and in the United States. He was, in fact, one of the most successful writers of his time in the country, and at the same time winning the admiration of fellow writers like Scott in Britain and Poe and Hawthorne in the United States.(76) The respect in which he was held partly owi ng to the man himself, with his warm frien dli ness, his good sen se, his urba nity, his gay spirits, his artistic in tegrity, his love of both the Old World and the New.Thackeray described Irving as "a gentleman, who, though himself born in no very high sphere,was most fini shed, polished, witty ; socially the equal of the most refined Europea ns. " ( 77 ) InEngland he was gran ted an honorary degree from Oxford--a n unu sual honor for a citize n of ayoung, un cultured n ati on--and he received the medal of the Royal Society of Literature. Americamade him ambassador to Spain.Irving's background provides little to explain his literary achievements. A gifted but delicate child, he had little schooli ng. He studied law, but without zeal, and n ever did practice seriously.He was immune to his strict Presbyterian home environment, frequenting both social gatheri ngs and the theater.1. The main point of the first paragraph is that Washington Irving wasA. America' s first man of lettersB. a writer who had great success both in and outside his own countryC. a man who was able to move from literature to politicsD. a man whose personal charm enabled him to get by with basically inferior work2. What is implied by the mention of Scott, Poe and Hawthorne?A. Irvi ng enjoyed great popular admirati on.B. Scott. Poe and Hawthorne were primarily responsible for Irving's success.C. lrving's work was not only popular, but also of high literary quality.D. More America ns tha n Brit ons admired Irvi ng.3. Which of the following best describes the effect of Irving' s Presbyterian backgro und on his life?A. It fostered his love for the theater.B. It developed his skill in bus in ess.C. It prompted his in terest in law.D. It had almost no effect on his life.4. Which of the following best describes the effect of Irving's personal qualities on his literary success?A. His personal qualities were entirely responsible for his literary success.B. His personal qualities were primarily responsible for his literary success.C. His pers onal qualities had some effects on his literary success.D. His pers onal qualities had no effects on his literary success.5. Why might Irving's literary ability have been surprising to the English?A. They feared competiti on from America n writers.B. They did not expect the United States to produce good writers.C. They disapproved of the Ian guage America n writers used.D. They thought of the United States as a purely commercial power.Passage 2Questions 6 to 10 are based on the following passage:Traditio nally, uni versities have carried out two main activities: research and teachi ng.Many experts would argue that both these activities play a critical role in serving the commun ity. The fun dame ntal questi on, however, is how does the com mun ity want or n eed to be served?In rece nt years uni versities have bee n coming un der in creas ing pressure from both the gover nments and the public to en sure that they do not rema in "ivory towers ( 象牙塔)"of study separated from the realities of everyday life. Un iversity teachers have bee n en couraged, and in some cases con stra ined (强迫),to provide more courses which produce graduates with the tech ni cal skills required for the commercial use. (78) If Aristotle wan ted to work in a uni versity in the UK today, he would have a good cha nee of teach ing computer scie nee but would not be so readily employable as a philosopher.A post-industrial society requires large numbers of computer programmers, engin eers, man agers and tech ni cia ns to mai nta in and develop its econo mic growth but "man", as the Bible says, "does not live by bread alone. " (79) Apart from requiri ng medical and social services, which do not directly con tribute to econo mic growth, the society should also value and enjoy literature, music and the arts. Because they can also promote economic growth. A successful musical play, for in sta nee, can con tribute as much to the Gross Natio nal Product through tourist dollars as any other thi ngs.6. The main idea of the first paragraph is thaLA. traditional universities do a good job serving the societyB. universities must meet the needs of the societyC. research and teachi ng are of great importa nee in uni versitiesD. universities play an important role in our society7. We can infer from the second paragraph that_A. the society is not satisfied with the present college educationB. the governments interfere too much with college educationC. teacher are forced to do what they don' t like to doD. teachers dislike teaching commercially useful courses8. The Aristotle example is used to make the point that_A. universities in the UK have produced too much good for graduatesB. such abstract subjects as philosophy is no Ion ger usefulC. education should serve the social needsD. it is advisable for today' s philosophers to know computer scienee9. According to the passage literature , music and the arts_A. do not con tribute to econo mic growth at allB. are less useful to the society because they do not make direct contribution to econo mic growthC. are similar to medical and social services in their way of promoting economic growthD. should develop only when they are good for economic growth10. The author believes that_A. art is useful only when it is made into a money earnerB. the promotion of economic growth is the only goal of today' s societyC. universities should not provide literature or art coursesD. the society needs both technical skills and artsPassage 3Questions 11to 1 5 are based on the following pass a geAll the useful en ergy at the surface of the earth comes from the activity of the sun'.The sun heats and feeds creatures and mankind Each year it provides men with two hundred million tons of grain and nearly ten million tons of wood , coal, oil, natural gas, and all other fuels are stored energy from the sun.(80)Some was collected by this seas on's pla nts as carb on compo un dsSome was stored by plants and trees ages agoEve n waterpower derives from the sun. Water turned in to vapor by the sun fails as rain. It courses down the mountains arid is converted to electric power:Light transmits only the energy that comes from the sun' s outer layer, and much of this en ergy that is directed towards the earth n ever arrives. About nine ten ths of it is absorbedby the atmosphere of the earth. In fact, the earth itself gets only one half millionth of the sun ' s entire output of radiant energy.11. The sun is the source of all of the following EXCEPTA. gasolineB. natural gasC. atomic powerD. animal fat12. Radia nt en ergy is stored as carb on compo unds byA. plantsB. waterC. rockD. creatures13. The sun' s energy provides US with all EXCEPTA. rainB. tealC. waterD. light14. The largest part of the light energy directed towards the earth isA. stored up by the plantsB. absorbed by the earth' s atmosphereC. stored up by the animals in the form of body fatD. used for electric power15 . Of me sun' s total output of radiant energy, the earth receives A . one ten thB . one millio nthC . all that comes from the surface of the sunD . a very small porti onPart II Vocabulary and Structure(3%)Directions In this part there are 30 incomplete sentenceSor each sentence there are your choices marked >B, C and D Choose the ONE answer that best completes the sentence Then mark the correspondingetter on the Answer Sheet with a single line through the center •16. You can t hear what I' m say in gyou stop talk ingA. only ifB. uni essC. lestD. except that17. He working fill he was seventy years oldA. kept up.B. kept onC. kept toD. kept out18. The novel ended happily, and the young couple was marriedA. in the finalB. in the endC. to the lastD. in conclusion19. One warning wasto stop her doing itA. sufferedB. sufficedC. suggestedD. provided20. It is estimated that the diseaseby polluted water will kill l out of every 100 childre nA. causingB. causedC. to causeD. will cause21. He didn' t know l was in his office. He was too busy tomeA. pay attention toB. noticeC. knowD. realize22. Will you show me the girl name is Jane7A. herB. who' sC. whoseD. which23. The old gentleman never fails to helpis in need of his help.A. whoB. whoeverC. oneD. whomever24. Mr. Holmes called at many schoolshe lived to ask them to accept his sqnbut he was refused everywhere for being a blackA. thatB. around whereC. near whichD. which25. My wallet is no where to be found. Iwhe n I was on the busA. must drop itB. should have dropped itC. must have dropped itD. had dropped it26. I could have done it better if Imore time.A . have hadB . hadC . had hadD . will have had27. _, we should be gladA. They arrive tomorrowB. Were they arriving tomorrowC. They were to arrive tomorrowD. Were they to arrive tomorrow28. I knew I could not finish my homework—A. by he had comeB. until he cameC. when he comesD. before he comes29. It is notthat this situation will last very Ion9 .A. alikeB. the likeC. likeD . likely 30 . Lon see ing the man age. The service in this hotel is terrible A . in sistB. persistC. affirmD. protest31. Experieneed teachers make mistakes than beginne【sA. lesserB. fewerC. not manyD. very few32. I prefer this book that one.A. more thanB. toC. thanD. rather than33. Do you know whQ fire to that Department Store?A. madeB. setC. startedD. caught34. All life on the earth on the sun.A. dependsB. carriesC. keepsD. goes35. I can' t keep_the teacher who speaks so fast.A. upB. up withC. withD. on with36. What the teacher said had a great_ on his later career.A. effortB. in flue neeC. resultD. expressi on37. Tom was such a football fan that he n eve^a sin gle game in the seas on.A. lostB. missedC. failedD. dropped38. Are you in terested_te nnis?A. i n playi ngB. for playi ngC. on play ingD. to play39. There were 30 stude nts and of them passed the exam.A. everyB. every oneC. every oneD. everybody40. the places I've bee n to, I enjo yed the restaura nt here the most.A. From allB. All ofC. of allD. All41. The quality of this kind of computer is to that of imported computers,A. worseB. i nferiorC. in differe ntD. much better42. I wish I could speak Fren ch_as Joh n.A. as goodB. as betterC. as wellD. as best43. _ speak in g, I think writ ing is rather bori ng.A. Hon estB. Hon estlyC. VeryD. Really44. If you don' t go, I shall not_A. eitherB. tooC. alsoD. yet45. My brother is now working_he did last year.A. much harder tha nB. more harder tha nC. more tha nD. much tha nPart ID Identification ( 10 % )Directions: Each of the following sentences has four underlined parts marked A, B, C and D. Identify the one that is not correct. Then mark the corresponding letter oa the Answer Sheet with a single line through the center.46.It is difficult to make yourself understand in a foreign country when you have no knowledge of—A_ _ _0 ― C Dits language.47.Noticing that my daughter shy. our hcstess wentj&ut of her way making her feel at_home.A― B ~C~ D48.What he does, he always docs k well, though he has some difficulties.B C - D49.Paula doesn' t want to attend die meeting and Sheila doesn+1 too,—r ~C D50.Since rhe beginning of this century T more and more scientists becom匕interested in the how the human brain works. D51.How can you do such tlnng without permission?A P ~^C — D52.]remember clearly 10 return the book to him last Wednesday, but now he says that L AB~C~―亍53.Passengers are warned not to get off a bus while moving.A — C _D54.A knowledge of several languages is essential to the study of comparative literature becauseAwithout them one can read only in translation.—C D55.。

高中英语高考模拟测试备考试题400

高中英语高考模拟测试备考试题400

高中英语高考模拟测试备考试题2019.101,In history, a real cowboy was a simple farm worker on horseback. He spent a long time a day outdoors working with __1_. The work was dirty, tiring and not very well paid.Most cowboys were young, unmarried men. A good horse made their job of moving cattle much easier. A good cowboy __2__ cows and knew how to control them. At night, he __3__ or played music to the cows to keep them calm.In the late 1800s, America was changing from a nation of farm to one of ___4__ and cities. The cowboy seemed ___5_ and out of control, compared with other Americans doing ordinary jobs.Today, the ___6__ of cowboys has ___7_ greatly. One change is the use of trucks. The job is not so hard __8__ it used to be. And cowboys are better ___9___ now. To their luck, they are __10___ to be married. Some of them are farmers or teachers or truck drivers, or work for big companies. But at night and on weekends, they become cowboys. These part-time cowboys increase the total production of meat, keeping on the beef price low.1.A.workers B. cows C. cowboys D. horses2.A. recognized B understood C owned D kept3.A. whisperer B. shouted C. cried D.sang4.A. towns B. factories C. companies D. villages5.A. free B. brave C. easy D. pleased6.A. manner B. job C. life D. mind7.A. changed B. developed C. broken D. realized8.A. that B. as C. which D. what9.A. known B. paid C. treated D. dresses10.A. afraid B. eager C. worried D. likely2,In history, a real cowboy was a simple farm worker on horseback. He spent a long time a day outdoors working with __1_. The work was dirty, tiring and not very well paid.Most cowboys were young, unmarried men. A good horse made their job of moving cattle much easier. A good cowboy __2__ cows and knew how to control them. At night, he __3__ or played music to the cows to keep them calm.In the late 1800s, America was changing from a nation of farm to one of ___4__ and cities. The cowboy seemed ___5_ and out of control, compared with other Americans doing ordinary jobs.Today, the ___6__ of cowboys has ___7_ greatly. One change is the use of trucks. The job is not so hard __8__ it used to be. And cowboys are better ___9___ now. To their luck, they are __10___ to be married. Some of them are farmers or teachers or truck drivers, or work for big companies. But at night and on weekends, they become cowboys. These part-time cowboys increase the total production of meat, keeping on the beef price low.1.A.workers B. cows C. cowboys D. horses2.A. recognized B understood C owned D kept3.A. whisperer B. shouted C. cried D. sang4.A. towns B. factories C. companies D. villages5.A. free B. brave C. easy D. pleased6.A. manner B. job C. life D. mind7.A. changed B. developed C. broken D. realized8.A. that B. as C. which D. what9.A. known B. paid C. treated D. dresses10.A. afraid B. eager C. worried D.likely3,_____ 1. You run a billboard advertising business you inherited(继承) from your father, and you are looking to expand in new directions. What do you do?_____ 2. You are a successful talk-show host, and have just achieved national recognition(认可). You want more control over your show, and a greater share of its profits. What do you do? _____3. You are still in college, but together with a friend you have established a software company that deals with major corporations. What do you do?_____ 4. You are a successful business analyst(分析师), and come to think that the mail-order business model could be adapted to online book sales. What do you do?_____ 5. You own several highly profitable waste-collection routes. The government has recently issued the Solid Waste Disposal Act, increasing standards of hygiene(卫生)in waste disposal. What do you do?A In 1968, H. Wayne Huizenga teamed with a partner to create a nationwide company for waste collection, a business traditionally made up of small, local companies. The new company, Waste Management, Inc., became the foundation of his fortune.B While attending Harvard University in 1975, Bill Gates teamed with Paul Allen to develop a version of the BASIC programminglanguage for the Altair 8800, the first personal computer. They licensed the software to the manufacturer of the Altair and formed Microsoft (originally Micro-soft) to develop versions of BASIC for other computer companies. Gates decided to drop out(退学) of Harvard in his junior year to devote his time to Microsoft.C In 1963, Ted Turner took over his family billboard-advertising business. In 1970 he bought a failing UHF(ultrahigh frequency) television station in Atlanta, Georgia, and by 1975 Turner had transformed it into the first “superstation”-WTBS, by transmitting(传送) low-cost sports and entertainment programs via satellite to cable systems throughout the country.D In 1986, Oprah Winfrey formed Harpo Productions to produce her own show and other projects. With distribution rights(销售权)to her shows, Winfrey used profits to expand her business activities. By 1998 Winfrey was worth $675 million.E Microsoft founder Bill Gates planned to give away almost all of his vast fortune, largely to the cause of global health. Having already the Bill & Melinda Gates Foundation with $ 24 billion to address global health issues, Gates said that eventually his entire fortune would be put towards the cause except “a few percent left for the kids.”F Amazon. com founder Jeff Bezos grew interested in online retailing(零售业) in 1994 while working as a business analyst in New York City. After researching the success of differentmail-order companies Bezos decided that books were the perfect product to see via the Internet. That year he left New York to establish his new company in Seattle, chosen for its being near to major book wholesalers and the advanced high-tech industry. In July 1995 Amazon. com developed its Web site, and has since expanded to offer many other retail products in addition to books.4,_____ 1. You run a billboard advertising business you inherited(继承) from your father, and you are looking to expand in new directions. What do you do?_____ 2. You are a successful talk-show host, and have just achieved national recognition(认可). You want more control over your show, and a greater share of its profits. What do you do? _____3. You are still in college, but together with a friend you have established a software company that deals with major corporations. What do you do?_____ 4. You are a successful business analyst(分析师), and come to think that the mail-order business model could be adapted to online book sales. What do you do?_____ 5. You own several highly profitable waste-collection routes. The government has recently issued the Solid Waste Disposal Act, increasing standards of hygiene(卫生)in waste disposal. What do you do?A In 1968, H. Wayne Huizenga teamed with a partner to create a nationwide company for waste collection, a business traditionally made up of small, local companies. The new company, WasteManagement, Inc., became the foundation of his fortune.B While attending Harvard University in 1975, Bill Gates teamed with Paul Allen to develop a version of the BASIC programming language for the Altair 8800, the first personal computer. They licensed the software to the manufacturer of the Altair and formed Microsoft (originally Micro-soft) to develop versions of BASIC for other computer companies. Gates decided to drop out(退学) of Harvard in his junior year to devote his time to Microsoft.C In 1963, Ted Turner took over his family billboard-advertising business. In 1970 he bought a failing UHF(ultrahigh frequency) television station in Atlanta, Georgia, and by 1975 Turner had transformed it into the first “superstation”-WTBS, by transmitting(传送) low-cost sports and entertainment programs via satellite to cable systems throughout the country.D In 1986, Oprah Winfrey formed Harpo Productions to produce her own show and other projects. With distribution rights(销售权)to her shows, Winfrey used profits to expand her business activities. By 1998 Winfrey was worth $675 million.E Microsoft founder Bill Gates planned to give away almost all of his vast fortune, largely to the cause of global health. Having already the Bill & Melinda Gates Foundation with $ 24 billion to address global health issues, Gates said that eventually his entire fortune would be put towards the cause except “a few percentleft for the kids.”F Amazon. com founder Jeff Bezos grew interested in online retailing(零售业) in 1994 while working as a business analyst in New York City. After researching the success of differentmail-order companies Bezos decided that books were the perfect product to see via the Internet. That year he left New York to establish his new company in Seattle, chosen for its being near to major book wholesalers and the advanced high-tech industry. In July 1995 Amazon. com developed its Web site, and has since expanded to offer many other retail products in addition to books. 5,Actually, we are making slow but s____________________ progress.6,Actually, we are making slow but s____________________ progress.7, Does life exist on other planets? Scientists are making every effort to find such e ________ _.8, Does life exist on other planets? Scientists are making every effort to find such e ________ _.9,Things can easily go wrong when people are under s____________________.10,Things can easily go wrong when people are under s____________________.11,Some a_______________ have got into the habit of taking drugs, so their parents are worried.12,Some a_______________ have got into the habit of taking drugs, so their parents are worried.13,Now that I am p______________ I eat a good diet because I want my baby to be born healthy.14,Now that I am p______________ I eat a good diet because I want my baby to be born healthy.15,Charles Keeling collected d__________ on the carbon dioxide content in the atmosphere.16,Charles Keeling collected d__________ on the carbon dioxide content in the atmosphere.17,The warming of the earth is a p____________ that causes great concern.18,The warming of the earth is a p____________ that causes great concern.19,Whenever I pass the KFC, I a______________ feel hungry. 20,Whenever I pass the KFC, I a______________ feel hungry.试题答案1, 1-5 BBDBA 6-10 CABCD2, 1-5 BBDBA 6-10 CABCD3, CDBFA4, CDBFA5, steady6, steady7, existence8, existence9, stress10, stress11, adolescents12, adolescents13, pregnant14, pregnant15, data16, data17, phenomenon18, phenomenon19, automatically20, automatically。

2024澳门药学 四级英语要求

2024澳门药学 四级英语要求

2024澳门药学四级英语要求全文共10篇示例,供读者参考篇1Hey guys, do you know that in 2024, there will be a new requirement for the Pharmacy Major in Macau? Yeah, that's right! You have to pass the Pharmacy English Level 4 exam!So, what's this exam all about? Well, let me tell you! The Pharmacy English Level 4 exam is designed to test your English skills in reading, writing, listening, and speaking. You have to show that you can communicate effectively in English, especially when it comes to pharmacy-related topics.To pass this exam, you need to be able to understand and respond to questions about pharmaceuticals, drug interactions, dosage calculations, and patient counseling. You also have to be able to write reports, prescriptions, and patient instructions in English. And don't forget about the speaking part - you'll have to participate in role-plays and discussions with your classmates in English.But hey, don't worry! You can prepare for this exam by practicing your English skills every day. Read English books,listen to English podcasts, and watch English movies. Try to speak English as much as you can, and don't be afraid to make mistakes - that's how you learn!So, if you want to excel in the Pharmacy Major in Macau in 2024, start preparing for the Pharmacy English Level 4 exam now. Good luck, and remember - practice makes perfect!篇2Hi everyone, I want to share with you about the English requirements for the 2024 Macau Pharmacy Level Four Exam. It's super important to prepare for this exam so we can pass with flying colors!First of all, we need to practice reading and writing in English every day. This will help us improve our vocabulary and grammar skills. We can read books, magazines, and even online articles to help us get better at English.Next, we need to practice speaking English with our friends and family. We can have conversations in English, watch English movies or TV shows, and even listen to English songs. This will help us get used to hearing and speaking English more fluently.In addition, we need to practice our listening skills by listening to English podcasts, radio shows, or even watching English videos. This will help us understand English better when we hear it spoken by others.Lastly, we need to make sure we are well-prepared for the exam by studying the exam materials and practicing past exam questions. This will help us feel more confident and ready to ace the exam!Let's work hard and practice English every day so we can pass the 2024 Macau Pharmacy Level Four Exam with flying colors! Good luck, everyone!篇3Hey guys, have you heard about the 2024 Macau Pharmacy Level Four English requirements? It's super important for us to know about this because it will help us do better in our English exams. Let me tell you all about it!First up, we need to practice our reading skills. That means reading lots of different kinds of texts like stories, articles, and even science journals. We need to understand what we read and be able to answer questions about it. Reading is so importantbecause it helps us improve our vocabulary and comprehension skills.Next, we need to work on our writing skills. We should practice writing essays, letters, and reports. We need to make sure our writing is clear, organized, and has good grammar. Writing is important because it helps us express our ideas and communicate effectively.Speaking of communication, we also need to practice our speaking skills. This means we should participate in class discussions, presentations, and debates. We need to be able to express ourselves confidently and clearly. Speaking is important because it helps us communicate with others and share our thoughts and opinions.Lastly, we need to focus on our listening skills. We should listen to English podcasts, watch English movies, and have conversations with native English speakers. We need to be able to understand different accents and dialects. Listening is important because it helps us improve our comprehension and communication skills.So, let's all work hard and practice our English skills so we can pass the 2024 Macau Pharmacy Level Four Englishrequirements with flying colors! Let's do our best and show everyone how awesome we are at English!篇4Oh wow, guys! Can you believe it? We have to write a super long article about the English requirements for the 2024 Macau Pharmacy Exam! It's gonna be so much fun!Okay, so let's get started. First off, we need to know that the English requirements for the exam are super important. We have to be able to read, write, listen, and speak English really well. That means we have to practice a lot and study really hard.For reading, we need to be able to understand all kinds of English texts. Like, we have to be able to read scientific articles about medicine and drugs. It's gonna be tough, but we can do it!Next up is writing. We have to be able to write essays and reports in English. We need to use proper grammar and spelling, and our ideas have to be clear and organized. So let's make sure we practice writing every day!Now, listening is super important too. We have to be able to understand English when people speak to us. That means wehave to practice listening to English podcasts, songs, and even watching English movies or TV shows. It's gonna be so much fun!And finally, speaking. We have to be able to speak English fluently and confidently. We need to practice speaking with our friends, teachers, or even in front of a mirror. Let's not be shy and just go for it!Okay, guys, I think we covered everything we need to know about the English requirements for the 2024 Macau Pharmacy Exam. Let's study hard, practice a lot, and we'll do great! Good luck, everyone!篇5Hey guys, today I want to talk about the English requirements for the 2024 Macau Pharmacy Level 4 exam. It's super important to be prepared for this test, so let's dive in and see what we need to know!First of all, make sure you practice your English every day. Read books, watch English movies, and talk to your friends in English. The more you practice, the better you'll get.Next, let's talk about the types of questions you might see on the exam. You could be asked to write a short essay, answermultiple-choice questions, or even have a conversation with the examiner. So make sure you're comfortable speaking and writing in English.It's also important to know your grammar and vocabulary. Learn new words every day and make sure you understand how to use them in sentences. And don't forget about grammar rules like verb tenses, subject-verb agreement, and word order.During the exam, try to stay calm and focused. Take deep breaths, read the questions carefully, and take your time answering them. And if you don't know the answer to a question, don't worry! Just do your best and move on to the next one.Finally, remember that practice makes perfect. The more you practice your English, the more confident you'll feel on exam day. So keep studying, keep practicing, and you'll ace the 2024 Macau Pharmacy Level 4 English exam!Good luck, guys! I know you can do it!篇6Yo guys, listen up! So, like, in 2024, they had this super cool event in Macau about pharmaceutics, you know, like medicine and stuff. And they were all like, "You gotta be good at English tobe in the game!" So, they set up this super tough English test called the Macau Pharmacy English Level 4, or something like that.Now, I know what you're thinking - English can be kinda boring, right? But, trust me, this test was actually really important! 'Cause in the world of pharmaceutics, you gotta know your stuff and communicate with people from all over the globe. And English is like the universal language for that, you know?So, this English test was all about testing your reading, writing, listening, and speaking skills. They wanted to see if you could understand medical jargon, write reports, listen to instructions, and chat with patients. It was like a real-life English challenge for aspiring pharmacists!But hey, don't worry too much! If you put in the effort and practice your English skills, you'll totally ace this test! Plus, it's not just about passing the test - it's about gaining the knowledge and skills to excel in the field of pharmaceutics.So, if you're thinking about joining the Macau Pharmacy English Level 4 party in 2024, get ready to brush up on your English skills and show 'em what you're made of! Who knows, you could be the next big thing in the world of pharmacy, all thanks to your awesome English skills! Remember, kids - Englishis not just a subject in school, it's a superpower that can take you places! Go get 'em!篇7Hey guys, today I want to talk about the English requirements for the 2024 Pharmacy exam in Macau. It's super important to have good English skills, because in the Pharmacy field, we need to communicate with patients and other healthcare professionals from all over the world.So, for the exam, we need to have a good understanding of English grammar, vocabulary, and reading comprehension. We also need to be able to write essays and reports in English. It's a lot of work, but it's worth it because it will help us become better pharmacists in the future.To improve our English skills, we can read English books and articles, watch English movies and TV shows, and practice speaking and writing in English every day. We can also join English study groups or take English classes to get more practice and feedback.Remember, the key to success in the Pharmacy exam is hard work and dedication. So let's study hard and to achieve ourdream of becoming great pharmacists in the future! Good luck to all of us!篇8Hey guys, guess what? I wanna tell you all about the English requirements for the 2024 Macau Pharmacy exam. So, let's dive right in!First things first, you gotta make sure you brush up on your English skills. This means practicing your reading, writing, speaking, and listening. You can do this by reading English books, watching English movies, chatting with your friends in English, and listening to English songs. The more you practice, the better you'll get!Next, remember to pay attention in English class at school. Your teacher will probably go over all the important stuff you need to know for the exam. Take notes, ask questions, and participate in class discussions. This will help you understand the material better and improve your English skills.Don't forget to study your vocabulary and grammar. Make flashcards, use language learning apps, or create your own study guide. Practice using new words and grammar rules in sentences to help you remember them better.When it comes to the exam, stay calm and focused. Read the instructions carefully, manage your time wisely, anddouble-check your answers before submitting your paper. Remember, it's okay to take a deep breath and relax if you feel nervous.Lastly, don't forget to review your mistakes after the exam. This will help you learn from them and improve for next time. Ask your teacher for feedback and advice on how to do better in the future.So there you have it, guys! Just follow these tips and you'll be sure to ace the 2024 Macau Pharmacy English exam. Good luck!篇9Hey guys! Today I want to talk about the English requirements for the 2024 Macau Pharmaceutical Four-level English test. It's super important to pass this test if you want to become a pharmacist in Macau, so let's get into it!First off, the test will cover four main areas: reading, writing, listening, and speaking. So make sure you practice all of these skills before the test day. For the reading section, you'll need tobe able to understand and analyze different texts, so read as much as you can in English to prepare.Next, the writing section will test your ability to express your ideas clearly and coherently. Practice writing essays and short paragraphs to improve your writing skills. The listening section will require you to understand spoken English, so listen to English podcasts, music, and videos to train your ears.Lastly, the speaking section will assess your ability to communicate in English. Practice speaking with friends or classmates in English, or even record yourself speaking and listen back to see how you can improve.Remember, practice makes perfect, so make sure you dedicate time to studying for the test. Good luck to everyone taking the 2024 Macau Pharmaceutical Four-level English test! You can do it!篇10Hello everyone, I'm a fourth grader in 2024 studying pharmacy in Macau. I want to share with you the English requirements for our pharmacy course.First of all, we have to be really good at reading and understanding English textbooks. There are so many big words in pharmacy that we need to know, like "pharmacokinetics" and "pharmacodynamics". It's like learning a secret code to understand how medicines work in our bodies.Secondly, we have to be able to write reports and essays in English. We have to explain our experiments and findings in a clear and organized way. Sometimes I feel like a little scientist writing my own research papers.Next, we have to speak English fluently in class presentations and group discussions. It's important to communicate our ideas effectively to our classmates and teachers. I always try to practice speaking English with my friends so I can improve my speaking skills.Lastly, we have to pass English exams to show our proficiency in the language. The exams test our reading, writing, listening, and speaking skills. It's like a big challenge for us, but we know that we have to do our best to succeed in our pharmacy studies.In conclusion, English is a very important subject for us pharmacy students. We need to work hard and practice regularly to meet the English requirements for our course. I'm excited tocontinue improving my English skills and becoming a successful pharmacist in the future. Thank you for listening to my article!。

制药工程专业英语考试题目及答案

制药工程专业英语考试题目及答案

专业英语考试内容:单词10分句子翻译24分根据课文回答问题24分英译汉药品说明书21分翻译汉译英摘要21分Unit 11 Tablet (The Pharmaceutical Tablets Dosage Form)药片(医药片剂剂型)Role in TherapyA: The oral route of drug admininistration is the most important method of administering drugs ofr systemic effects.Except in cases of Insulin therapy.the parenteral route is not routinely used for self-administration of medication.The topical route of administration has only recently been employed to deliver drugs to the body for systemic effects,with two classes of marketed products:Nitroglycerin for the treatmint of angina and scopolamine for the treatment of motion sickness.Other drugs are certain to follow,but the topical route of administration is limited in its ability to allow effective drug absorption for systemic drug action.A:口服给药是全身效应用药方法中最为重要的。

除了胰岛素治疗,非肠道药途径不常用在自我服药方面。

-广东省高考英语新题型第三次新题测试卷(无附听力材料)新课标 人教版

-广东省高考英语新题型第三次新题测试卷(无附听力材料)新课标 人教版

2006-2007学年广东省高考英语新题型第三次新题测试卷(无附听力材料)本套试题依照2007年广东高考新题型命制,共分四大部分,满分150分,考试时间为120分钟第一部分:听力(共两节,满分32.5分)作题时,先将答案划在试卷上。

录音内容结束后,你将有两分钟的时间将试卷上的答案转涂到答题卡上,并将“获取信息”答案填写在答题纸上。

第一节:听力(共15小题;每小题1.5分;满分22.5分)听下面五段对话或独白。

每段对话或独白后有几个小题,从题中所给的ABC三个选项中选出最佳的选项,并标在试卷的相应位置。

听每段对话或独白前你将有时间阅读各个小题,每小题5秒钟。

听完后,每个小题将给出5秒钟的作答时间。

每段对话或独白读两遍。

听第一段对话,回答第1--3小题。

1. What is the possible relationship between the speakers?A. Classmates.B. Mother and son.C. Teacher and student.2. Why does the woman try to persuade the man to ppare for the exam?A. Because Professor Johnson will get angry otherwise.B. Because everyone should pass the exam.C. Because the test will be difficult.3. What does the man finally decided to do?A. To study for the test.B. To watch the football game.C. To eat something before watching the game.听第二段对话,回答第4--6小题。

4. Where does the conversation most probably take place?A. At a railway station.B. At an airport.C. In a hotel.5. Why can’t the man himself help carry the luggage?A. Because he has to report to the manager first.B. Because he’s on the phone at the moment.C. Because he cannot leave the desk.6. What will the man probably do?A. He will do nothing for the woman.B. He will find a way to help her.C. He himself will send her to the station.听第三段对话,回答第7--9小题。

高考英语模拟考试卷三试题_1

高考英语模拟考试卷三试题_1

2021年高考英语模拟考试卷三本套试卷分第一卷〔选择题〕和第二卷〔非选择题〕两局部。

一共150分。

考试时间是是120分钟。

第I卷 (两局部,一共100分)第一局部:英语知识运用(一共两节,满分是50分)第一节:单项填空(一共20小题;每一小题1分,满分是20分)从A、B、C、D四个选项里面,选出可以填入空白处的最正确选项,并在答题纸上将该选项标号涂黑。

1. — Our team will play against the Rockets this weekend. I’m sure we will win.— _____!A. Good luckB. CheersC. Best wishesD. Congratulations2. The number of deaths from heart disease will be reduced greatly if people _____ to eat more fruit and vegetables.A. persuadeB. will persuadeC. be persuadedD. are persuaded3. — _____ you please write a 3000-word report about this subject for me?— Perhaps I _____ only write a 1000-word one, but I even doubt it.A. Could; mightB. Would; mightC. Might; couldD. Would; could4. Alice used to smoke _____ but she has given it up.A. seriouslyB. heavilyC. badlyD. hardly5. Not only _____ give us relaxation and pleasure, but also ___ increase our knowledge.A. can travel; it canB. travel can; can itC. can travel; can itD. travel can; it can6. You’d better take something to read when you go to see the doctor _____ you have to wait.A. even ifB. in caseC. as ifD. in order that7. It was foolish of him to ________ his notes during that important test, and asa result, he got punished.A. stick toB. refer toC. keep toD. point to8. _____ recent report stated that the number of Spanish speakers in the U.S. would be higher than the number of English speakers by _____ year 2090.A. A; theB. A; 不填C. The; 不填D. The; a9. He speaks English well indeed, but of course not _____ a native speaker.A. as fluent asB. more fluent thanC. so fluently asD. much fluently than10. The most common thing to do on the earth can be a big threat if _____ properly,according to Chen Shanguang, designer of the spaceship.A. doesn’t handleB. not handledC. not handlingD. having not handled11. —It’ll take at least 2 hours to do this!— Oh, _____! I could do it in 30 minutes.A. come onB. pardon meC. you are rightD. is that true12. It is not so difficult to learn programme well. _____ you need is patience andpersistence.A. SomethingB. AllC. BothD. Everything13. “Premier Wen’s report,〞a smile on his face, he continued, “_____ to severalhot topics, discusses how to increase peasants’ income, in a comparative part.〞A. referringB. refersC. having referredD. referred14. —Could you type these papers for me, please?— _____ papers? I have been busy for a whole day.A. WhatB. SomeC. MoreD. Different15. It was unbelievable that the fans waited outside the gym for three hours just_____ a look at the sports stars.A. hadB. havingC. to haveD. have16. Bill is good at playing football, but when comes to basketball, he knowsnothing.A. heB. thatC. thisD. it17. You must try some of her home-made wine—it’s quite a(n) _____.A. experienceB. experimentC. effortD. skill18. After a lengthy discussion, they finally_____ up with a suggestion for solvingthe problem.A. wentB. cameC. keptD. looked19. ―Why was Professor Wang unhappy recently?―Because the theory he insisted on _____ wrong.A. being provedB. provingC. provedD. was proved20. Sally was _____ to see her friend off at the airport.A. a little sad more thanB. more than a little sadC. sad more than a littleD. a little more than sad第二节:完型填空〔一共20小题;每一小题1.5分,满分是30分〕阅读下面短文,掌握其大意,然后从21—40各题所给的四个选项〔A、B、C和D〕中,选出最正确选项,并在答题纸上将该选项标号涂黑。

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e-Everything: e-Commerce, e-Government, e-Household, e-Democracy14th Bled Electronic Commerce ConferenceBled, Slovenia, June 25 - 26, 2001e-Pharmacy (.au):A Successful Online Pharmacy in AustraliaMichael S. Lane, Andy KoroniosDepartment of Information Systems, Faculty of Business and CommerceUniversity of Southern Queensland, West st ToowoommbaQueensland, Australia, 4350LaneM@.au, Koronios@.au1. IntroductionBrett Clark had been pondering the potential of an online pharmacy for some time now. A practising pharmacist with a business interest in three retail pharmacies in the Brisbane metropolitan area, he already thoroughly understood the retail pharmacy business, but knew little about the Internet and electronic commerce. He hired David Vandenberg from a Web development company: ‘The Lab’ to assist him in assessing the viability of an online pharmacy in the Australian market place and to develop a business plan for his proposed Internet Startup: ePharmacy.The ePharmacy site (.au) was launched in March 2000 with the main objective of selling pharmacy goods at very competitive prices. Brett Clark hired Sasha, a dedicated employee for order processing, fulfilment, customer relationship management and routine maintenance of the site and utilised his existing pharmacy staff in advisory capacity. Initially, ePharmacy’s market reach was expected to be limited to Australia largely due to the restrictions on the sale of certain pharmaceutial goods that require a written prescription from a medical practitioner. Brett Clark felt that there were significant business opportunities for an online pharmacy given that retail pharmacy industry in Australia was worth in excess of 10 Billion annually. Little attempt have been made to develop a serious online pharmacy presence due to the highly regulated nature of retail pharmacy in Australia. There was a reluctance on the part of pharmacists to adopt new business models when they could make a comfortable living from a traditional retail pharmacy where there were significant barriers to entry in the market place.710e-Pharmacy (.au): A Successful Online Pharmacy in Australia2. Background – Retail Pharmacy in Australia2.1 Pharmacy regulation in AustraliaThe retail pharmacy industry in Australia is worth about 10 Billion Dollars annually and the industry is highly regulated. There are a number of barriers to entry. Retail Pharmacy is regulated in terms of ownership, location of pharmacies to dispense benefits of Pharmaceutical Benefits Scheme (PBS) and registration of pharmacists (National Competition Review of Pharmacy 2000).Pharmacy Ownership. Allowing for some variations in each State Act, and the specified exceptions of friendly societies and some grandparented proprietors (that is, for profit non-pharmacist proprietors whose holdings predate existing restrictions), by and large only registered pharmacists may own pharmacies (National Competition Review of Pharamcy 2000). There are also a number of issues relating to the commercial operation of pharmacies which may be affected by professional regulation in State and Territory Acts. These include: how many pharmacies may a proprietor own, ownership structures for pharmacy businesses, third party pecuniary interests in pharmacy businesses and regulatory authorities registering both pharmacy premises and businesses.Pharmacy Location. Under the National Health Act 1953, the Commonwealth Government of Australia imposes strict controls on approving new pharmacies and on relocating existing pharmacies for Pharmarceutical Benefits Scheme (PBS) dispensary purposes. These location-based controls help to give effect to the Australian Community Pharmacy Agreement between the Commonwealth and the Pharmacy Guild of Australia.Pharmacy Registration. To obtain registration, the all jurisdictions require a pharmacist to have a recognised qualification from a tertiary institution in Australia or overseas, and to complete a period of pre-registration training. The State and Territory Pharmacy Acts reserve the privilege of practising pharmacy to registered pharmacists. The supply of drugs and poisons is only permitted by non-pharmacists in very limited circumstances. In addition, most jurisdictions protect the lawful use of the term ‘pharmacist’, pharmaceutical chemist’ and similar titles and descriptions by restricting these to registered pharmacists. Acts and regulations also impose restrictions on the professional conduct of pharmacists including: prescribed ethical and professional standards and related disciplinary sanctions; and limitations on advertising such as the Queensland prohibition of advertising leading to invidious comparison with other pharmacists (Queensland Pharmacy Regulations 1997). Furthermore, pharmacy has become a more difficult profession to enter. The period of university training has risen from three to four years, and the effective minimum pre-registration period (including academic study) has increased to five years.711Michael S. Lane, Andy Koronios712 2.2 National Health System and Pharmacy in Australia National health system. In Australia, certain pharmaceutical goods such as prescription medicines can only be obtained from a pharmacist with a written prescription from a practising medical practitioner for several reasons. This restricts the misuse of certain drugs and also many drugs are heavily subsided by the national health system. The pharmaceutical benefits scheme (PBS) allows the pharmacists to provide certain prescribed medicines etc.. at highly subsided rates. To own and operate a retail pharmacy in Australia, you need to be a qualified pharmacist. Furthermore, a prescription from a medical practitioner is needed to purchase certain types of pharmaceutical goods from a pharmacy. Typically in Australia, a pharmacist can earn a good living from a traditional retail pharmacy business. The industry is highly regulated which has created a number of barriers to entry. Hence there has been a reluctance for pharmacists to adopt new business models.3.Overview of Case - ePharmacyePharmacy is a new startup Internet company and was initiated as a business idea by one of principal directors, Brett Clark in June 1999. It was kept separate from bricks and mortar pharmacy for legal and dispensary reasons. A Web developer David Vandenberg (The Lab) was employed to assist in investigating the potentiale-Pharmacy (.au): A Successful Online Pharmacy in Australiaof an online pharmacy and to develop a business plan. “We spend six months developing the site before we went live in March 2000” (Brett Clark). ePharmacy runs a very small operation with only three people involved in running and maintaining the site. Brett Clark has a hands on involvement role, an employee is responsible for order processing, fulfilment, customer relationship management and routine maintenance (updating stock information etc). A web development company ‘The Lab’ (David Vandenberg) built the initial web site and is responsible for hosting, maintaining and enhancing the site.ePharmacy was developed as a functional site designed specifically for selling pharmaceutical and associated products. Sales have increased at a rate in excess of 20 percent per month. In the twelve months to date, the site has sold in excess of $500,000 worth of product mainly prescriptions, the usual over the counter analgesics and the like (Liddle 2001). Seventy percent of customers are those with regular prescriptions who leave their repeat orders with Epharmacy. A significant segment of product sales consist of sex related products such as virility drugs, condoms and flavoured gels. Customers are offered significant discounts to shop online such as: 15-20 percent on feminine hygiene products, up to 30 percent on medication, up to 30 percent stop smoking products and 25-30 percent on baby products.A supplier delivers any requested stock twice a day, six days a week at no charge from ePharmacy’s 15,000 item online catalogue. One supplier provides over 80 percent of ePharmacy’s stock and is located in close proximity. ePharmacy’s physical store at Calamvale, Brisbane holds $300,000 worth of stock. Plans are afoot in the near future to open a megastore in Brisbane that will sell direct to the public and serve as a warehouse. The megastore will include Internet Kiosks to encourage self service.When a customer places a order online that requires a prescription, the order form is printed out and signed by the customer, and mailed to a reply-paid address along with the prescription. Nearly 70 percent of customers leave repeat prescriptions with ePharmacy for convenience. The orders are printed out and entered in a portable data entry device linked to a phone line and placed with the supplier. Australia Post picks up the order from the Calamvale store and delivers to anywhere in Australia. The business uses one PC in the Calamvale store, a laptop to enable Brett Clark to work from home and owns a server hosted by a Brisbane company.At present, there is very little serious competition to ePharmacy in the form of online pharmacies operating in Australia. Other sites in Australia are using a network relay where a customer places an order which is relayed to the nearest local pharmacist. The pricing structure of this approach is too difficult for the participating pharmacists and the consumers. Since, pharmacists can earn a good living from a traditional pharmacy practice, there is been little pressure on pharmacists to adopt new business models such as an online pharmacy. Furthermore, ePharmacy has the advantage of operating in a highly regulated industry where there are barriers to entry such as restrictions on ownership and location of pharmacies, and the required registration of practising pharmacists.713Michael S. Lane, Andy KoroniosHence, there is a largely untapped market of online consumers for pharmaceutical goods in Australia.4. Case Findings4.1 Value PropositionsThe value propositions that ePharmacy can provide for the customer are primarily price and convenience. “Price is driving our business” (Brett Clark), and “ePharmacy’s prices are rock bottom” (web development company). 70 percent of customer sales are repeat prescriptions. “Because 80 percent of our stock comes from one supplier in close proximity and we receive two stock deliveries per day, we can normally deliver within 48 hours of an order being placed over the Internet. Our customers are often surprised how quickly we can fulfil an order. We use Australia Post to deliver our orders” (Marketing employee). As the business grows opportunities will emerge for other value propositions such collaborative advertising with pharmacuetical suppliers to provide exposure and promotion for new and existing products.4.2 Marketing of SiteePharmacy had operating for less than 12 months, hence it was necessary to launch the business with advertising campaign. The advertising campaign was initiated with an article on ePharmacy in the Financial Review, Brett Clark appeared in an interview on a national television show “Good Medicine”. Banner advertising was negotiated with Australia’s premier web portal Ninemsn which registers something in the order of 16 million page impressions per day. The purpose of the advertising campaign was to generate traffic to the site and to establish credibility by building a brand name in the minds of the consumers. “After the viewing of ePharmacy’s launch on the Health and Lifestyle Television show ‘Good Medicine’ site traffic trebled” (Marketing employee). Brett Clark noted that “The more hits you get, the more business you are going to get”. After the initial branding campaign on Ninemsn, ePharmacy switched to the newer shopping portals Clickandeasy amd CyberRewards in February 2001. The pricing policy of these portals is based on clickthroughs and a percentage of transactions.A large amount of ePharmacy’s success has been due to engaging a public relations firm (Kath Rose and Associates) to conduct regular press releases in different media outlets Australia wide. “The results has been astounding, I have had over 10 newspaper stories, three TV stories, three talkback radio shows and numerous articles in different publications. I always believed that traditional pharmacy which is considered old tie coupled with would make for an interesting story” (Brett Clark).714e-Pharmacy (.au): A Successful Online Pharmacy in Australia715The marketing of products, services and information needed to be integrated as the main objective of the site to sell pharmacy products at low prices. The site needed to be very functional and provide the appropriate level of information to facilitate a sale whether payment was made online or offline. There are a number of legal and ethical issues to consider when selling pharmacy products and these issues must be addressed in the online environment as well (Daniels 2000). Customers are required to register with site before they are able to order online and certain pharmacy products require a written prescription from a medical practitioner. Delivery of customer orders is by certified mail which requires a signature and is a deterrent to credit card fraud. Customer relationship management was considered a priority and all customer inquiries were answered individually within a 48 hour turnaround time. The site was focused towards providing the necessary information and functionality to meet the needs of the consumer during the pre purchase, purchase and post purchase phases of a customer transaction.Pre purchase PhaseInformation andFunctionality Purchase Phase Information and Functionality Post Purchase Phase Information and FunctionalityGenerate traffic to the site through advertising campaign both online and offline Search Facility Promotional information Product and related health and beauty informationPrivacy statementSecurity statementLegal liability statementRegister with siteProduct catalogue Shopping basket Different payment methods Settlement of Payment Delivery methods FAQ Customer order notificationOrder tracking facilityDelivery of Order byAustralia PostCustomer support and serviceTable 1: Information and functionality supporting customer transaction phases4.3 ResourcesInternally, ePharmacy has a dedicated employee whose main activities are the processing of orders, fulfilment and to provide customer support. ePharmacy also provides customers with the ability to consult a pharmacist during business hours. External partners provided some of essential services associated with the online pharmacy. Australia Post provided distribution network for the delivery of orders in the fulfilment cycle. The fulfilment of orders was enhanced by the fact that 80 percent of the orders came from one supplier located in close proximity and that ePharmacy received two deliveries from this supplier. This arrangement enhanced their ability to fulfil orders in a timely manner. A secure payment gateway ensures that the settlement of online orders over the Internet is secure. The authentication ofMichael S. Lane, Andy Koroniosthe site was enhanced by a third party certificate authority. The Lab (.au) provided the necessary technical expertise to develop, maintain and enhance the site.After the site initially went live, the web developer has an ongoing contract to perform 40 hours work on the site each month. Brett Clark and web developer meet on a monthly basis and discuss and prioritise enhancements and future directions for the site. It is envisaged that a major redevelopment of the site will be needed within the next six months due to the rapid growth of the site. The web developer’s approach to building web sites is to keep the technology simple on client side and to utilise the power of new web technologies such as Java and ActiveX on the backend server side. ePharmacy has been designed to be a functional site that gets the customer through the phases of a customer transaction as quickly and seamlessly as possible. But at the same the site provides enough information for the various levels of users through links to more detailed information. Brett Clark is actively involved in the development, maintenance and enhancement of ePharmacy. “At first, I didn’t know anything about the Web but I learnt by talking to everyone involved in electronic commerce that I dealt with ” (Brett Clark).4.4 Financial ModelsRevenueePharmacy’s revenue is generated from product sales and to an lesser extent from advertising. ePharmacy is primarily concerned with selling pharmacy products online and in order to generate a volume of sales required a sufficient level of site traffic. Interestingly, 20 percent of sales are classified as mail order, in that the customer prints out the order form from the site and places the order through the mail. This has presented ePharmacy with the opportunity to diversify into the lucrative pharmacy direct mail order business. Once sufficient levels of site traffic are generated, other business opportunities such as advertising and cross selling will arise. ePharmacy is particularly interested in advertising as another means of generating revenue from the site.Revenue GrowthThe present growth rate of ePharmacy has been so rapid that it has placed a strain on the current assets and resources of the company. Floating the company will allow the business to keep growing by providing the necessary capital to diversify and expand the business activities of ePharmacy and ultimately expand its revenue streams. Plans are already underway to open a megastore in Brisbane in the near future which will serve as a warehouse and will sell direct to the public.716e-Pharmacy (.au): A Successful Online Pharmacy in AustraliaShareholder ValueePharmacy is a private company, therefore shareholder value is not presently an issue. In order to keep the company growing, the directors of the company are considering plans to float the company to raise the necessary capital. Hence, in the future shareholder value will become an issue if the company proceeds with plans to float the company on the Australian Stock market as an Initial Public Offer (IPO).5. DiscussionePharmacy has been successful through a combination of pharmacy experience, good business planning and marketing and web development experience. The retail pharmacy industry in Australia is highly regulated which creates significant barriers to entry. An intimate knowledge of the industry and the associated legal, ethical and political issues was necessary for an online pharmacy to succeed. Brett Clark was mindful fact that ePharmacy’s business activities and behaviour would be closely watched by the Pharmacy Guild of Australia (.au) and the Pharmaceutical Society of Australia (.au). These pharmacy professional organisations have significant political power regulate the conduct of practising pharmacists. Therefore, it was important to be open and accountable to these professional organisations in the pharmacy industry. An online pharmacy in Australia is subject to the same controls as other suppliers of prescription medicines.Brett Clark elected to initially build the business plan around existing bricks and mortar stores utilising existing staff and existing alliances with wholesalers and suppliers. “I also could not understand the amount of capital that s were outlaying for branding and advertising. There seems to be a lot of ignorance about business. They have spend millions on advertising but do not seem to understand the basic principles of retailing. I initially knew nothing about the technology but I understand retail pharmacy” (Brett Clark).ePharmacy was designed to be a functional web site that supports the purchase of pharmacy and associated goods while at the same time providing sufficient product and associated information to attract and retain customers. Furthermore, the customer is able to talk to a qualified pharmacist or the customer relationship management employee if further information is required. ePharmacy has also achieved significant competitive advantage through its close proximity to its largest supplier which provides two deliveries per day. This coupled with the extensive distribution network of Australia Post has facilitated the prompt and efficient fulfilment of customer orders.The potential for an online pharmacy will be greatly enhanced in the future by forthcoming legislation (July 2001) that will allow the electronic transmission of pharmaceutical prescriptions. ePharmacy also is planning to expand into the lucrative direct mail business. The market reach of ePharmacy is extensive within Australia and the overseas market is growing rapidly. In the near future, a717Michael S. Lane, Andy Koroniosmegastore will sell direct to the public and serve as a warehouse to support this rapid growth. Still, given the recent demise of many s with burn-rates that were not sustainable, ePharmacy cannot afford to be complacent and will face increased competition in the future.ReferencesClickandeasy, [Online], [Available: .au/],[Accessed 20th January 2001]CyberRewards, [Online], [Available: .au/],[Accessed 20th January 2000]Daniels, A. Surfers of the Net unite! IT’s the revolution you need, Australian Pharmacist, [Online], [Available: .au/], [Accessed 15thJanuary 2001].Enos, L. Net Pharmacies Missing Mark, [OnLine], [Available: http:/news/articles2000/001020-6.shmtl], [Accessed:25 January 2001]ePharmacy, [Online], [Available: .au],[Acessed: 25th January 2001]Liddle, T. Epharmacy’s profit secrets, Enterprise Watch, [Online], [Available: .au/r/article/jsp/sid/335882], [Accessed: 5th February 2001]National Competition Policy, Review of Phamacy, [Online], [Available: .au/haf/pharmrev/final.htm], [Accessed: 2nd February2001]The Lab, [Online], [Available: .au], [Accessed: 25 January 2001]Note: The teaching note for this case is available on request from the Authors718。

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