Meropenem_96036-03-2_DataSheet_MedChemExpress
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Product Name:
Meropenem CAS No.:
96036-03-2Cat. No.:
HY-13678Product Data Sheet
MWt:
383.46Formula:
C17H25N3O5S Purity :>98%
DMSO 77 mg/mL; Water 8 mg/mL;Solubility:Mechanisms:
Biological Activity:
M i b tibi ti hi h di l i b d t f tib t i l ti it
Pathways:Anti-infection; Target:Antibacterial SO g/;ate 8g/;Ethanol <1 mg/mL
Meropenem is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity.
Target: Antibacterial Meropenem, a new parenteral carbapenem demonstrated increased activity as compared to
imipenem against 336 strains of Neisseria gonorrhoeae, 119 strains of Haemophilus influenzae, and 110 strains of H. Ceftriaxone and ciprofloxacin demonstrated activity superior to that of both
carbapenems while the activity of ceftazidime was similar to that of meropenem [1]. Meropenem, like imipenem and various experimental penems, may overcome the resistance problems presented by Class I beta-lactamases [2]. MEROPENEM was rapidly penetrated to the pleural effusion and was retained for a more prolonged time in the pleural effusion than in the blood of patients with References:
[1]. Slaney, L., et al., In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother, 1989. 24 Suppl A: p.
183-6.retained for a more prolonged time in the pleural effusion than in the blood of patients with
accumulated pleural effusion, and it suggested the usefulness of MEROPENEM in antibacterial therapy f...
[2]. Yang, Y.J. and D.M. Livermore, Interactions of meropenem with class I chromosomal beta-
lactamases. J Antimicrob Chemother, 1989. 24 Suppl A: p. 207-17.[3]. Makino, J., et al., [Pharmacokinetic study of penetration of meropenem into pleural effusion in
patients with pleurisy]. Jpn J Antibiot, 2002. 55(1): p. 77-88.Caution: Not fully tested. For research purposes only
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