老年肺部感染病原菌120例分析

老年肺部感染病原菌120例分析
邝敏齐;叶巧珍;叶贵梅
【期刊名称】《中国医药科学》
【年(卷),期】2013(3)15
【摘要】Objective To analyze the types and drug resistance of pathogens of the elderly patients with pulmonary infection. Methods 120 elderly patients with pulmonary infection treated in our hospital from October 2010 to August 2012 were selected,of which 75 patients complicated by chronic obstructive pulmonary disease were established as group A and 45 patients not complicated by chronic obstructive pulmonary disease were established as group B.All the patients received sputum bacteriological culture and drug susceptibility test.The pathogen types of patients were analyzed and the antibiotics drug resistance rate,cure rate and mortality of the two groups of patients were compared. Results Gram-negative bacteria were the main pathogens of elderly pulmonary infection,which accounted for 86.6%and 78.2%of the total infected persons of group A and group B respectively,of which Pseudomonas aeruginosa, Klebsiella pneumoniae and Pseudomonas ranked the top three of infection percentage.Group B was higher than group A in the Streptococcus pneumoniae infection rate,with statistical between-group
difference(P<0.05).The drug resistance rates of cefotaxime,cefazolin and cefoperazone of group A were 53.3%,58.7% and 54.7% and those of group
B were 35.6%,40.0%and 37.8%;Group A was significantly higher than group B in all the drug resistance rates of cefotaxime, cefazolin and cefoperazone,with statistically significant between-group differences(P < 0.05).The cure rate and mortality of group A were 57.3%and
9.3%respectively and those of group B were 75.6%and
2.2%respectively;Group A was significantly higher than group B in both cure rate and mortality,with statistically significant between-group differences (P<0.05). Conclusion The major pathogens of elderly pulmonary infection were gram-negative bacteria and the patients complicated by COPD had more severe bacteria drug resistance.Clinical treatment should pay attention to the rational usage of antibiotics in order to effectively reduce mortality and improve prognosis.%目的分析老年肺部感染患者病原菌类型及耐药性。

方法选取我院2010年10月~2012年8月收治老年肺部感染患者120例，其中合并慢性阻塞性肺疾病者75例，设为A组，未合并
慢性阻塞性肺疾病者45例，设为B组，均探讨行痰细菌学培养和药物敏感试验，分析患者病原菌感染类型，比较两组患者抗生素耐药率，治愈率及死亡率等。

结果老年肺部感染患者以革兰阴性菌感染为主，A组和B组分别占总感染人数86.6%，78.2%，其中铜绿假单胞菌，肺炎克雷伯菌及假单胞菌均居于感染百分比前3位；B组患者肺炎链球菌感染率明显高于A组，组间比较差异有统计学意义（P＜
0.05）；A组患者头孢噻肟、头孢唑林及头孢哌酮耐药率分别为53.3%，58.7%，54.7%；B组患者头孢噻肟、头孢唑林及头孢哌酮耐药率分别为35.6%，40.0%，37.8%；A组患者头孢噻肟、头孢唑林及头孢哌酮耐药率均明显高于B组，组间比较差异有统计学意义（P＜0.05）；A组患者治愈率及死亡率分别为57.3%，
9.3%；B组患者的治愈率及死亡率分别为75.6%，2.2%；A组患者治愈率及死亡
率均明显高于B组，组间比较差异有统计学意义（P＜0.05）。

结论老年肺部感染患者病原菌以革兰阴性菌为主，合并COPD患者细菌耐药较严重；临床治疗应当注重合理应用抗生素，以有效降低死亡率，改善预后。

【总页数】3页(P179-180,188)
【作者】邝敏齐;叶巧珍;叶贵梅
【作者单位】广东省东莞市大朗医院,广东东莞,523770;广东省东莞市大朗医院,广东东莞,523770;广东省东莞市大朗医院,广东东莞,523770
【正文语种】中文
【中图分类】R541.5
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