动脉粥样硬化性脑桥梗死与腔隙性脑梗死的临床和影像学特征比较分析

动脉粥样硬化性脑桥梗死与腔隙性脑梗死的临床和影像学特征
比较分析
张远锦;董荃;方可;樊东升;李小刚
【期刊名称】《中华老年心脑血管病杂志》
【年(卷),期】2017(19)10
【摘要】目的探讨动脉粥样硬化性脑桥梗死与腔隙性脑梗死的临床表现及影像学特征.方法回顾性分析北京大学第三医院神经内科住院的急性孤立性脑桥梗死患者67例,其中脑桥梗死组36例,腔隙性脑梗死组31例.根据神经功能恶化时间又分为
早期神经功能恶化(END)组17例,非END组50例.比较危险因素、临床症状体征、影像学特征和实验室结果.结果脑桥梗死组男性、入院收缩压、脂蛋白(a)水平明显高于腔隙性脑梗死组,脑微出血比例明显低于腔隙性脑梗死组,差异有统计学意义(P
＜0.05).END组TC明显高于非END组,空腹血糖明显低于非END组(P＜0.05,P＜0.01).logistic回归分析显示,低血糖和高TC血症是END的预测因素
(OR=0.719,95％CI:0.553～0.933,P=0.013;OR=0.611,95％CI:0.391～
0.954,P=0.030).结论动脉粥样硬化性脑桥梗死患者男性居多,腔隙性脑梗死脑微出血比例较高,END与低血糖、高TC有关.%Objective To study the clinical and imaging characteristics of atherosclerotic pontine infarction and lacunar ischemic stroke.Methods Sixty-seven acute isolated pontine infarction patients admitted to our hospital were divided into pontine infarction group (n=36) and lacunar ischemic stroke group (n=31) and further divided into early neurological detrioration (END) group (n=17 and non-END group (n=50) according to their END time.The risk factors,clinical
symptoms and signs,imaging characteristics and laboratory testing data of atherosclerotic pontine infarction and lacunar ischemic stroke were compared.Results The ratio of male patients was greater in pontine infarction group than that of lacunar ischemic stroke group.The SBP and serum lipoprotein (a) level were significantly higher in pontine infarction group than in lacunar ischemic stroke group on admission (P＜0.05).The incidence of cerebral microbleeds was significantly lower in pontine infarction group than in lacunar ischemic stroke group (P＜0.05).The serum TC level was significantly higher and the serum fasting blood glucose level was significantly lower in END group than in non-END group (P＜0.05,P＜0.01).Logistic regression analysis showed that hypoglycemia and hypercholesterolemia were the risk factors for END (OR=0.719,95 ％
CI:0.553-0.933,P=0.013;OR=0.611,95％CI:0.391-0.954,P=0.030).Conclusion The ratio of male atherosclerotic pontine infarction patients is greater than that of female.END is related with hypoglycemia and hypercholesterolemia in atherosclerotic pontine infarction and lacunar ischemic stroke patients.【总页数】5页(P1062-1066)
【作者】张远锦;董荃;方可;樊东升;李小刚
【作者单位】100191 北京大学第三医院神经内科;民航总医院神经内科;100191 北京大学第三医院神经内科;100191 北京大学第三医院神经内科;100191 北京大学第三医院神经内科
【正文语种】中文
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