即刻种植修复联合牙周基础治疗对慢性牙周炎患者血清及龈沟液中TNF-α、IL-1β及IL-6水平的影响

即刻种植修复联合牙周基础治疗对慢性牙周炎患者血清及龈沟液中TNF-α、IL-1β及IL-6水平的影响
黄海霞;付小明;伍宝琴;郭玲;刘敏;兰玉燕
【期刊名称】《中国美容医学》
【年(卷),期】2018(27)2
【摘要】Objective To investigate the effects of immediate implant-repair combined with periodontal treatment on chronic periodontitis and the levels of TNF-α, IL-1β and IL-6 in serum and gingival crevicular fluid. Methods 89 cases of patients with chronic periodontitis admitted to our hospital from September 2015 to September 2017 were enrolled in this study. All patients were divided into the control group (n=43) and the study group (n=46) according to random number table. The patients in the control group were received the basic periodontal treatment, and the patients in the study group were received immediate implant repair combined with periodontal treatment. The Periodontal clinical parameters (PD, PLI, AL, BI) before and after treatment and inflammatory cytokines levels in both groups were observed and compared. Results After the treatment, the levels of PD, PLI, AL and BI in both groups were lower than those before treatment, and the study group was lower than the control group (P<0.05). The levels of serum TNF-α, IL-1β and IL-6 after treatment in both groups were lower than those before treatment, and the difference was statistically significant (P<0.05). After the treatment, the levels of TNF-
α, IL-1β and IL-6 in gingival crevicular fluid in both groups were lower than those before treatment, and the levels in the study group were lower than those in the control group (P<0.05). Conclusion Immediate implants combined with periodontal treatment of chronic periodontitis significant effect, can effectively improve the periodontal situation, reduce serum, gingival crevicular fluid inflammatory cytokine levels worthy of clinical promotion.%目的:研究即刻种植修复联合牙周基础治疗对慢性牙周炎患者血清及龈沟液中TNF-α、IL-1β及IL-6水平的影响.方法:选取2015年9月-2017年9月在本院接受诊治的89例慢性牙周炎患者作为研究对象,根据随机数表法分为对照组和研究组.对照组43例患者接受牙周基础治疗,研究组46例患者采用即刻种植修复联合牙周基础治疗.比较两组患者治疗前后牙周临床指标(PD、PLI、AL、BI)、炎性因子水平变化.结果:治疗后两组患者的PD、PLI、AL、BI水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);治疗后两组患者的血清TNF-α、IL-1β、IL-6水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05);治疗后两组患者龈沟液内TNF-α、IL-1β、IL-6水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05).结论:即刻种植修复联合牙周基础治疗慢性牙周炎效果显著,能有效改善牙周情况,减轻血清、龈沟液炎性因子水平,值得临床推广.【总页数】5页(P87-91)
【作者】黄海霞;付小明;伍宝琴;郭玲;刘敏;兰玉燕
【作者单位】西南医科大学附属口腔医院修复科(口颌面修复重建与再生实验室) 四川泸州 646000;重庆医科大学附属口腔医院修复科(口腔疾病与生物医学重庆市重点实验室,重庆市高校市级口腔生物医学工程重点实验室) 重庆 401147;西南医科大学附属口腔医院牙周黏膜科(口颌面修复重建与再生实验室) 四川泸州 646000];西
南医科大学附属口腔医院修复科(口颌面修复重建与再生实验室) 四川泸州646000;西南医科大学附属口腔医院修复科(口颌面修复重建与再生实验室) 四川泸州 646000;西南医科大学附属口腔医院修复科(口颌面修复重建与再生实验室) 四川泸州 646000
【正文语种】中文
【中图分类】R781.4
【相关文献】
1.复方大黄五倍子含漱液联合牙周基础治疗对慢性牙周炎患者龈沟液IL-6、TNF-α及hs-CRP水平的影响 [J], 吴迪;梁晋;徐新玉
2.牙周基础治疗配合即刻种植修复对慢性牙周炎患者炎性因子水平及牙周指标的影响 [J], 李点典;崔云峰;李硕
3.激光联合牙周基础治疗对种植体周围炎患者龈沟液中TNF-α、b-FGF及IL-1β水平的影响 [J], 董方;李艳莉;童远武
4.慢性牙周炎患者牙周基础治疗前后龈沟液中IL-6、TNF-α及hs-CRP水平的变化 [J], 付汉斌
5.头孢克肟联合甲硝唑对慢性牙周炎患者牙周指标及龈沟液IL-1β和TNF-α水平的影响 [J], 曾宇
因版权原因，仅展示原文概要，查看原文内容请购买。