手足口病合并心肌损害患儿的心肌酶CK-MB的检测及临床意义

手足口病合并心肌损害患儿的心肌酶CK-MB的检测及临床
意义
潘海贤;黄奕辉;林明祥
【期刊名称】《临床和实验医学杂志》
【年(卷),期】2012(011)006
【摘要】Objective To evaluate the changes and clinical significance of serum myocardial enzyme CK - MB in diagnosis of myocardial impairment in children with hand, foot and mouth disease ( HFMD ). Methods The clinical data of serum levels of CK - MB in 67 cases of HFMD with myocardial impairment during 2010 to 2011 were retrospectively analyzed, and 66 healthy children were allocated into control group. The results of serum levels of CK - MB were also compared before and after treatment. Results The abnormal rate of serum level of CK - MB in children with HFMD and myocardial impairment were significantly higher than those of control group ( P <0.01 ). The abnormal rate of post - treatment serum level of CK - MB was significantly lower than that of pre - treatment serum level of CK - MB. Conclusion Myocardial enzyme CK - MB can be used as a valuable indicator for diagnosis and observation of the degree of myocardial impairment, and predicting the prognosis of children with HFMD and myocardial impairment.%目的观察手足口病合并心肌损害患儿的心肌酶肌酸激酶混合同工酶(CK-MB)的变化及临床意义.方法选择2010~2011年67例手足口病合并心肌损害患儿,检测治疗前血清CK-MB的水平,同时检测66例健康
儿童作为对照.并且将治疗前后的CK-MB检测结果进行对比.结果手足口病合并心肌损害患儿治疗前CK-MB的活性为32.67±17.82 IU/L,异常率为62.69%,明显高于正常对照组(P<0.01).治疗后CK-MB的活性为16.38±4.44 IU/L,异常率为
2.99%,明显低于治疗前患儿的CK-MB 的活性和异常率(P<0.01).结论测定手足口病患儿血清心肌酶CK-MB水平有助于了解心肌损害程度,对临床诊治及预后判断具有重要意义.
【总页数】2页(P413-414)
【作者】潘海贤;黄奕辉;林明祥
【作者单位】汕头市中心医院儿科,广东,汕头,515041;汕头市中心医院儿科,广东,汕头,515041;汕头市中心医院儿科,广东,汕头,515041
【正文语种】中文
【相关文献】
1.小儿手足口病合并心肌损害36例心肌酶谱检测结果分析 [J], 朱洪学;童涛
2.小儿手足口病合并心肌损害患者心肌酶谱检测结果分析 [J], 陈雪华
3.CK-MB 及 cTnI 检测对手足口病患儿心肌损害的临床意义 [J], 汤淑斌;庞伟斌
4.小儿手足口病合并心肌损害心肌酶CKMB检测及影响因素分析 [J], 高侠;刘璐
5.重症手足口病患儿合并肺炎支原体感染的心肌酶、淋巴细胞亚群及免疫球蛋白检测的临床意义 [J], 覃小矿; 侯云生; 黄肖孝
因版权原因，仅展示原文概要，查看原文内容请购买。