匹多莫德治疗小儿反复下呼吸道感染的疗效分析

匹多莫德治疗小儿反复下呼吸道感染的疗效分析
顾慧东;李裕昌;邱晓菊;邓永锋
【期刊名称】《临床医学工程》
【年(卷),期】2016(023)007
【摘要】目的：观察匹多莫德对下呼吸道感染患儿的治疗效果。

方法选取我院60例因下呼吸道反复感染入院治疗的小儿患者，分为常规组和联合组，每组30例。

常规组给予抗感染及对症支持治疗，联合组在常规组基础上加用匹多莫德，观察两组患儿临床疗效、免疫水平变化情况及复发情况。

结果联合组治疗总有效率显著高于常规组（93.3%vs 73.3%），复发率显著低于常规组（3.3%vs 20.0%），
P<0.05。

两组治疗后IgA、 IgM、 IgG水平均显著升高，且联合组免疫水平改善程度显著优于对照组， P<0.05。

结论常规抗感染及对症支持治疗对小儿反复呼吸道感染有一定疗效，但复发率较高，若与匹多莫德联合治疗不仅可提高患者免疫能力，减少疾病复发情况，且可有效提高治疗效果。

%Objective To observe the treatment effect of pidotimod for children with repeated lower respiratory tract infection. Methods 60 children admitted to our hospital because of repeated lower respiratory tract infection were equally divided into conventional group and combined group. The conventional group was given anti-infection therapy and symptomatic supportive treatment, the combined group was given pidotimod on this basis. The clinical efficacy, changes of immune levels and relapse situations in two groups were observed. Results The total effective rate of combined group was significantly higher than that of control group (93.3%v s 73.3%), the
recurrence rate was significantly lower than that of control group (3.3%vs 20.0%), P<0.05. After treatment, the IgA, IgM and IgG levels in two groups increased significantly, and the improvement degree of immune level in combined group was better than that in control group, P <0.05. Conclusions Although conventional anti-infection therapy and symptomatic supportive treatment have certain curative effect on infantile repeated respiratory infection, the recurrence rate is high. The combination therapy of the treatment method and pidotimod can not only improve the patients' immune ability, reduce the disease relapse, but also effectively improve the treatment effect.
【总页数】2页(P893-894)
【作者】顾慧东;李裕昌;邱晓菊;邓永锋
【作者单位】广东省肇庆市高要区人民医院，广东肇庆526040;广东省肇庆市高要区人民医院，广东肇庆526040;广东省肇庆市高要区人民医院，广东肇庆526040;广东省肇庆市高要区人民医院，广东肇庆526040
【正文语种】中文
【中图分类】R725.6
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