富血小板纤维蛋白在牙周植骨手术中的临床观察

富血小板纤维蛋白在牙周植骨手术中的临床观察
雷朝锋;王英博;徐屹
【期刊名称】《牙体牙髓牙周病学杂志》
【年(卷),期】2017(027)009
【摘要】目的:观察第二代血小板浓缩物富血小板纤维蛋白(PRF)和植骨材料联合应用在牙周植骨手术中的疗效.方法:纳入20名慢性牙周炎牙槽骨垂直吸收的患者,随机分为试验组和对照组(n=10).试验组植入PRF碎片和Bio-Oss骨粉混合物,再覆盖PRF膜,对照组仅植入Bio-Oss骨粉.分别于术前和术后6个月进行探诊深度(PD)、附着水平(AL)、Mazza出血指数(BI)检查,并进行骨内袋(IBD)影像学测量.结果:试验组和对照组术后PD、AL、BI、IBD均优于术前(P＜0.05).术后6个月,试验组PD、AL优于对照组(P＜0.05),BI、IBD两组间无统计学意义(P＞0.05).结论:治疗慢性牙周炎弧形骨缺损时,PRF配合Bio-Oss骨移植物的使用可以促进软、硬组织的愈合,而对于成骨作用有限.%AIM:To observe the effects of second-generation platelet concentrated platelet-rich fibrin (PRF) on the periodontal tissue healing.METHODS:20 patients with intra-bony defects of chronic periodontitis were randomly divided into the test and the control groups (n =10).The patients in test group were treated with PRF and Bio-Oss combination,those in the control were treated with Bio-Oss
alone.Probing depth (PD),attachment level (AL),Mazza bleeding index (BI) and radiographic measurements of intra-bony defect(IBD) were recorded at pre-surgical baseline and 6 months post-operatively.RESULTS:All the clinical and radiographic parameters of the 2 groups were improved after
treatment(P ＜0.05).Mean PD reduction and AL gain in test group were more than in the control group(P ＜ 0.05).No statistically significant difference was found in BI and IBD between 2 groups.CONCLUSION:PRF combined with Bio-Oss bone graft may accelerate periodontal soft and hard tissue healing.
【总页数】4页(P525-528)
【作者】雷朝锋;王英博;徐屹
【作者单位】北京大学口腔医院第三门诊部,北京100191;北京大学口腔医院第三门诊部,北京100191;四川大学华西口腔医院牙周科,四川成都610041
【正文语种】中文
【中图分类】R781.4
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