SELF-ASSEMBLING NANOPARTICLES FOR THE TREATMENT O
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申请人：HELMUS, Michael, N. 地址：US,US 国籍：US,US 代理机构：PARK, Keum, J. 更多信息请下载全文后查看
wk.baidu.com
摘要：The present invention is directed to the formation of structures in situ through the principles of ligand binding. These structures are efficacious, for example, for tissue repair as well as for short- and long-term disease and condition management. According to one aspect of the invention, an injectable composition comprising self-assembling nanoparticles is provided. The self-assembling nanoparticles include: (a) a nanoparticle portion, (b) tissue binding ligands attached to the nanoparticle portion, which cause preferential binding and accumulation of the nanoparticles at one or more targeted tissue locations upon injection of the composition into the body, and (c) first and second interparticle binding ligands attached to the nanoparticle portion, which cause interparticle binding upon injection of the composition into the body.
专利内容由知识产权出版社提供
专利名称：SELF-ASSEMBLING NANOPARTICLES FOR THE TREATMENT OF VASCULAR DISEASES
发明人：HELMUS, Michael, N. 申请号：US2006033633 申请日：20060825 公开号：WO07/025274 P 1 公开日：20070301
wk.baidu.com
摘要：The present invention is directed to the formation of structures in situ through the principles of ligand binding. These structures are efficacious, for example, for tissue repair as well as for short- and long-term disease and condition management. According to one aspect of the invention, an injectable composition comprising self-assembling nanoparticles is provided. The self-assembling nanoparticles include: (a) a nanoparticle portion, (b) tissue binding ligands attached to the nanoparticle portion, which cause preferential binding and accumulation of the nanoparticles at one or more targeted tissue locations upon injection of the composition into the body, and (c) first and second interparticle binding ligands attached to the nanoparticle portion, which cause interparticle binding upon injection of the composition into the body.
专利内容由知识产权出版社提供
专利名称：SELF-ASSEMBLING NANOPARTICLES FOR THE TREATMENT OF VASCULAR DISEASES
发明人：HELMUS, Michael, N. 申请号：US2006033633 申请日：20060825 公开号：WO07/025274 P 1 公开日：20070301