氟康唑对预防早产儿静脉高营养并发感染的疗效分析

氟康唑对预防早产儿静脉高营养并发感染的疗效分析
王楠楠
【期刊名称】《辽宁医学院学报》
【年(卷),期】2014(000)002
【摘要】目的：探讨氟康唑对预防早产儿静脉高营养并发症的疗效。

方法选取48例在我院接受静脉高营养的早产儿，将他们平均分成实验组和对照组，每组各24例，对照组在静脉高营养时未采用药物进行预防并发感染，实验组采用静脉滴注氟康唑的方法来预防早产儿静脉高营养并发感染，观察并比较两组早产儿并发感染的情况。

结果实验组的真菌感染率为12.50％（3/24），显著低于对照组的真菌感
染率37.50％（9/24），差异有统计学意义（ P＜0.05）；实验组治疗后早产儿患者家属的总满意度为74.16％（19/24），显著高于对照组的41.67％（10/24），差异有统计学意义（ P＜0.05）。

实验组治疗后的不良反应发生率为4.16％
（1/24），显著低于对照组治疗后的不良反应发生率25.00％（6/24），差异有
统计学意义（ P＜0.05）。

结论采用静脉滴注氟康唑的方法来预防早产儿静脉高营养并发感染效果明显，大大降低了真菌的感染率，早产儿患者的家属满意度较高，此种方法对早产儿不会造成不良影响，安全性高，值得在临床上推广应
用。

%Objective To explore the efficacy of fluconazole on the prevention of intravenous hyperalimentation complicated by infection among premature infants.Methods 48 premature infants with intravenous hyperalimentation
in the hospital were divided into two groups-the experimental group and the control group, 24 cases in each group.The control group were not treated with medicines to prevent complicated infection while the
experimental group were treated with intravenous drip.Infants of both groups were observed in terms of infection.Results The fungal infection rate of experimental group was 12.50% (3/24), remarkably lower than that of the control group, which is 37.50%(9/24).The difference of fungal infection rate between the two groups was of statistical significance
(χ2=4.000, P<0.05).The family satisfaction of prema ture infants from the experimental group was 74.16% (19/24), remarkably higher than that of the control group, which is 41.67% (10/24).The difference was of statistical significance (P<0.05).The inci-dence of adverse reactions of experimental group was 4.16% ( 1/24 ) , which is greatly lower than that of the control group 25.00%(6/24).The difference was statistically significant (χ2=2.6760, P>0.05).Conclusion When preventing intravenous hyperali-mentation complicated by infection among premature infants, it is very effective to use fluconazole through intravenous drips, which can bring down the fungal infection rate and enhance family satisfaction of the
infants.Therefore, this method should be clinically applied due to its high-security and less side effect.
【总页数】3页(P49-51)
【作者】王楠楠
【作者单位】安徽医科大学第二附属医院儿科，安徽合肥 230601
【正文语种】中文
【中图分类】R722.1
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