美国药典规定色谱柱类型
USP色谱柱的翻译
L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称C18或ODS L2：30～50um表面多孔薄壳型键合C18(ODS)固定相L3：多孔硅胶微粒即一般的硅胶柱L4：30～50um表面多孔薄壳型硅胶L5：30～50um表面多孔薄壳型氧化铝L6：30～50um实心微球表面包覆磺化碳氟聚合物－强阳离子交换固定相L7：全多孔硅胶微粒键合C8官能团固定相简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相L10：多孔硅胶微球键合氰基固定相（CN）简称CN柱L11：键合苯基多孔硅胶微球固定相简称苯基柱L12：无孔微球键合季胺功能团的强阴离子填料L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1）简称C1柱L14:10um硅胶化学键合强碱性季铵盐阴离子交换固定相简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换树脂L18: 3～10um全多孔硅胶化学键合胺基（NH2）和氰基（CN）L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换树脂L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol）简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球L22：带有磺酸基团的多孔苯乙烯阳离子交换树脂L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换树脂L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相L27：30～50um的全多孔硅胶微粒L28：多功能载体，100?的高纯硅胶加以氨基键合以及C8反相键合的官能团L29: 氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5um，孔径80? L30: 全多孔硅胶键合乙基硅烷固定相L31: 季胺基改性孔径2000?的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33: 能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相,pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9um球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150?L36: 5um胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40,000Mw的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43: 硅胶微球键合五氟代苯基固定相L44: 多功能固定相,60 ?高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46: 季胺基改性苯乙烯-二乙烯基苯聚合物微球。
符合美国药典的各种分析色谱柱Dr.maisch
Reprosil PAC
USP-L19
由磺化的苯乙烯-二乙烯基苯交连共聚物组成的钙型阳离子交换树脂，粒径7-11u
Reprogel Ca++
USP-L20
二甲氧基丙烷基化学键合于多孔硅胶微粒，粒径5-10u。
Reprosil 100 Diol
Reprosil-Pur Diol
Reprosil100 C8
Reprosil-Pur C8
Reprosil Gold C8
Reprosil -Pur Basic C8 (HD)
Reprosil80 C8
Reprospher C8 (DE)
Equisil BDS C8
USP-L8
全多孔硅胶微粒键合非交联NH2固定相
Reprosil 100 NH2
Reprosil-Pur C18-AQ
Reprosil-Pur ODS-3
Reprosil Gold C18
Reprosil Saphir C18
Reprosil 80 ODS-2
Reprosil-Pur Basic C18 (HD)
Reprospher C18 (DE)
Equisil ODS
Equisil BDS C18
USP-L34
铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9mm球形
Reprogel PΒιβλιοθήκη , 9 μmUSP-L36
5mm胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰
Reprosil Chiral-PhenylGlycin
USP-L37
适合分离分子量2000～40000MW的聚甲基丙烯酸酯凝胶
美国药典色谱柱分类.
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter. L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter. L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter. L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter. L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter. L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter. L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter. L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating. L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter. L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter. L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating. L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter. L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter. L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter. L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter. L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonicacid groups,about 10µm in size. L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size. L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5 L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable. L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter. L27—Porous silica particles,30to 50µm in diameter. L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality. L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å. L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter. L31—Astrong anion-exchange resin-quaternary amine bonded on latexparticles attached to a core of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter. L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6 L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter. L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å. L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica. L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel. L38—Amethacrylate-based size-exclusion packing for water-soluble samples. L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20µm in diameter. L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm indiameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter. L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter. L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality. L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter. L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7 L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter. L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8 L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coatedwith quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9 L51—Amylosetris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10 L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11 L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12 L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13 L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14 L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15 L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µm in diameter,with a pore size of 120Å. L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28 L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28L1是C18柱L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
美国药典USP气相色谱柱对照表
美国药典USP气相色谱柱对照表美国药典USP气相色谱柱对照表L62 C30硅胶键合于完全多孔球状硅胶，粒径3~15μm。
G48 Highly polar, partially cross-linked cyanopolysiloxane.Rt-2560G46 14% 氰丙基苯基- 86% 甲基聚硅氧烷CB-1701MXT?-1701Rtx?-1701VF-1701ms OV-1701CBX-1701DB-1701DB-1701P G43 6% 氰丙基苯基- 94% 二甲基聚硅氧烷MXT?-624DB-624MXT?-Volatiles CBX-1301 MXT?-1301OV-1301CB-624Rtx?-1301 VF-624ms/VF-1301ms Rtx?-624CB-1301CBX-624 G42 35% 苯基- 65% 二甲基乙烯聚硅氧烷DB-35Rtx?-35MXT?-35CBX-35HP-35DB-35MSG38 固定相G1 加减尾剂MXT-1Rtx?-1MS Rtx?-1G36 1% 乙烯基- 5% 苯基甲基聚硅氧烷Rtx?-5MS Rtx?-5CBX-5MXT?-5G35 聚乙二醇和硝基对苯二甲酸二乙二醇酯DB-FFAP HP-FFAP CB-FFAPG32 20% Phenylmethyl-80% dimethylpolysiloxane.MXT?-20G27 5% 苯基- 95% 甲基聚硅氧烷CB-5XTI?-5Rtx?-5SIL MS VF-5msRtx?-5PONA HP-5MS HP-5DB-5MSSE-52DB-5SE-54G25 聚乙二醇TPA（Carbowax 20M 对苯二酸）FFAP CBX-FFAPG19 25% 苯基- 25% 氰丙基甲基聚硅氧烷OV-225Rtx?-225VF-23ms CBX-225G17 75% 苯基- 25% 甲基聚硅氧烷MXT?-65G16 聚乙二醇（平均分子量15,000）DB-WAX CBX-Wax CB-WAX Stabilwax?PEG-20M Stabilwax?-DB Stabilwax?-DA MXT?-WAXG15 聚乙二醇（平均分子量3000－3700）Rtx?-WaxG14 聚乙二醇（平均分子量950－1050）VF-WAXmsG8 90％3氰基丙基－10％苯基甲基聚硅氧烷HP-88Rtx?-2330G7 50%-3-氰丙基聚硅氧烷-50%苯甲基硅氧烷DB-225CB-225G6 三氟丙基甲基聚硅氧烷MXT?-200Rtx?-200G5 3-氰丙基聚氧硅烷DB-23G3 50%苯基-50%甲基聚硅氧烷(50% Phenyl-50% methylpolysiloxane)DB-17HT Rtx?-50Rtx?-17VF-17msMXT?-50DB-17MS CBX-17HP-50+DB-17CB-17VF-Xms OV-17G2 二甲基聚硅烷胶（Dimethylpolysiloxane Gum)CB-1MXT?-1HT Sim Dist HP-1DB-1MSCB-101VF-1ms DB-1MXT?-1 Sim DistHP-PONAG1 二甲基聚硅氧烷油（Dimethylpolysiloxane oil)SE-30CBX-1CB-101CB-PONARtx?-1PONA OV-101OV-1CB-TVOC0 其他分类(气相填充柱色谱柱)L1 十八烷基硅烷化学键合到多孔硅胶或陶瓷微粒，粒径为1.5 到10 μmL10 腈基化学键合到多孔硅胶颗粒，粒径为3 到10 μmL11 苯基化学键合到多孔硅胶颗粒，粒径为1.5 到10 μmL14 具有化学键合的、强碱性季铵阴离子交换涂层的硅胶，粒径为10 μmL18 氨基和氰基化学键合到多孔硅胶颗粒，粒径为5 到10 μmL2 十八烷基硅烷化学键合到表面孔隙度可控制的多孔硅胶（已键合到固体球形核），粒径为3到50 μm L20 二羟基丙烷基化学键合到多孔硅胶颗粒，粒径为3 到10 μmL3 多孔硅胶颗粒，粒径为5 到10 μmL56 丙基硅烷化学键合到全多孔硅胶颗粒，粒径为3 到10 μmL7 辛基硅烷化学键合到全多孔微硅胶颗粒，粒径为1.5 到10 μm L8 氨丙基硅烷以单分子层形式化学键合到多孔硅胶载体上，粒径为10 μmS10 丙烯晴和二乙烯基苯高交联共聚物S1A 硅藻土S2 苯乙烯－二乙烯基苯共聚物：比表面小于50m2/g，平均孔径0.3-0.4umS3 苯乙烯－二乙烯基苯共聚物：比表面为50－6000m2/g，平均孔径0.0075umS4 苯乙烯－二乙烯基苯共聚物（含-O和-N）：比表面为400－600m2/g，平均孔径0.0076umS6 苯乙烯－二乙烯基苯共聚物：比表面为250－350m2/g，平均孔径0.0091umS7 石墨化碳比表面12 m2/gS8 4-乙烯吡啶和苯乙烯二乙烯基苯共聚物G0 其他分类CB-AL2O3/S LZP-950CBX-Phenol PLOT GDX-102农残C农残A农残B CB-PLOT QLZP-920LZP-930LZP-940CB-Metal APLOT GDX-202PLOT GDX-501CB-PLOT U MXT?-500 Sim Dist VF-35ms Rtx?-VMS Rtx?-2887Rtx?-20Rtx?-VGC CB-PLOT Silica FAMEWAX CB-202PLOT GDX-502CBX PLOT-5A MXT?-BAC1CB-AL2O3/MRt-βDEXsa Rtx?-502.2PLOT TDX-01B PLOT TDX-03 PLOT GDX-403PLOT GDX-401MXT?-BAC2HP-PLOT QCB-204Rt-βDEXsp PLOT GDX-203CBX-Dexsil 300 HP-PLOT 氧化铝/S Rtx?-VRX PLOT GDX-103Rt-SPLOTPLOT GDX-201C-2000MXT?-2887PLOT TDX-02B PONA MXT?-502.2PLOT GDX-105苯甲酚专用柱CB-PLOT 5A Rtx?-CLPesticides2Rtx?-440PLOT GDX-303苯系物专用柱DB-608Rtx?-CLPesticides CB-Dexsil 300Rt-βDEXcst Rtx?-PCB MXT?-65TG Rt-βDEXseCB-201Rtx?-XLB Rt-βDEXsm Rt-QPLOTPLOT GDX-104CB-BasicWax PLOT GDX-101CB-PLOT SPLOT GDX-301VF-200ms。
USP药典L1～L60对应色谱柱
下面分别是USPL1～L60的对映。
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter.L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter.L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating.L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter.L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating.L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter.L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10µm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size.L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter.L27—Porous silica particles,30to 50µm in diameter.L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality.L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å.L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached toa core of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter.L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å.L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel.L38—Amethacrylate-based size-exclusion packing for water-soluble samples.L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20µm in diameter.L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter.L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality.L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter.L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter.L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9L51—Amylose tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µm in diameter,with a pore size of 120Å.L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28。
【VIP专享】USP药典L1～L60对应色谱柱
下面分别是USPL1～L60的对映。
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter.L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter.L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating.L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter.L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating.L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter.L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10µm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size.L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter.L27—Porous silica particles,30to 50µm in diameter.L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality.L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å.L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached toa core of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter.L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å.L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel.L38—Amethacrylate-based size-exclusion packing for water-soluble samples.L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20µm in diameter.L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter.L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality.L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter.L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter.L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9L51—Amylose tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µm in diameter,with a pore size of 120Å.L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28。
美国药典中的色谱柱编号
L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，3-10u。
L2 Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 μm in diameter.L2 十八烷基键合硅烷化学键合于表面空隙率一定的键合在紧密球核上的硅胶，粒径30-50u。
L3 Porous silica particles, 5 to 10 μm in diameter.L3 多孔硅胶颗粒，粒径5-10u。
L4 Silica gel of controlled surface porosity bonded to a solid spherical core,30 to 50 μm in diameter.L4 表面空隙率一定的硅胶键合于紧密球核上，粒径30-50u。
L5 Alumina of controlled surface porosity bonded to a solid spherical core,30 to 50 μm in diameter.L5 表面空隙率一定的氧化铝键合于紧密球核上，粒径30-50u。
L6 Strong cation-exchange packing: sulfonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 μm in diameter.L6 强阳离子交换填料：磺化氟代烃聚合物涂渍于紧密球核上，粒径30-50u。
L7 Octyl silane chemically bonded to totally porous silica particles, 1.5 to 10 μm in diameter.L7 辛基硅烷化学键合于完全多孔硅胶担体，粒径10u。
【免费下载】美国药典色谱柱型号对照
美国药典色谱柱型号对照下面是USP规定的编号所对应的色谱柱类型。
L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW 范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：30～50mm的全多孔硅胶微粒L28：多功能载体，100Å的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5mm，孔径80ÅL30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000Å的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相, pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150ÅL36:5mm胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40000MW的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60 Å高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，3-10u。
美国药典色谱柱型号比较
美国药典色谱柱型号对照下面是USP规定的编号所对应的色谱柱类型。
L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW 范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：30～50mm的全多孔硅胶微粒L28：多功能载体，100Å的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5mm，孔径80ÅL30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000Å的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相, pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150ÅL36:5mm胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40000MW的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60 Å高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，3-10u。
usp美国药典液相方法色谱柱汇总
usp美国药典液相方法色谱柱汇总USP美国药典液相方法色谱柱类型汇总USP即美国药典，为高效液相色谱柱填料规定了一些指标，并根据类型进行了序列编排，即USP L1---USP L60系列。
USP 填料描述L1 C18烷基化学键合于多孔硅胶或陶瓷微粒，3-10u L2 C18烷基化学键合于多孔硅胶，30-50u L3 多孔硅胶微粒，5-10uL4 硅胶微粒，30-50uL5 氧化铝微粒，30-50uL6 强阳离子交换填料:磺化氟碳聚合物涂于固体球形核粒上，30-50u L7 C8烷基化学键合于3-10u完全多孔硅胶微粒 L8 单分子层丙氨基化学键合于10u硅胶载体， L9 强酸性阳离子交换基团键合于10u无定形多孔硅胶， L10 氰基化学键合于5-10u多孔硅胶颗粒， L11 苯基化学键合于5-10u多孔硅胶颗粒， L12 季铵基化学键合于30-50u固体硅胶小球上，强阴离子交换填料 L13 三甲基硅烷化学键合于5-10u多孔硅胶颗粒， L14 带强碱性季铵基的阴离子交换涂料化学键合于10u硅胶微粒， L15 六烷基化学键合于全多孔硅胶颗粒，3-10u L16 二甲基化学键合于全多孔硅胶颗粒，5-10u L17 强阳离子交换树脂:氢型、磺化交联的苯乙烯二乙烯基苯共聚物，7-11u L18 氨基和氰基官能团键合于5-10u的多孔硅胶颗粒上 L19 强阳离子交换树脂:钙型、磺化交联的苯乙烯二乙烯基苯共聚物，9u L20 二羟基丙烷基团化学键合于多孔硅胶颗粒，5-10u L21 刚性的苯乙烯二乙烯基苯共聚物小球，5-10u L22 阳离子交换树脂:带磺酸基团的多孔苯乙烯聚合物小球，外径约10u阴离子交换树脂:带季铵基团的聚甲基丙烯酸甲酯或聚丙烯酸甲酯多孔胶体，约10u外L23 径L24 基体表面带大量羟基团的聚乙烯构成的半刚性亲水凝胶，32-63u外径该填料应能分离分子量从100-5000道尔顿的化合物，用于分离中性，阳离子型及阴离子L25 型的水溶性聚合物。
美国药典(USP)中规定的色谱柱类型
美国药典（USP）中规定的色谱柱类型Chromatographic ReagentsThe following list of packings (L), phases (G), and supports (S) is intended to be a convenient reference for the chromatographer. [note—Particle sizes given in this listing are those generally provided. Where other, usually finer, sizes are required, the individual monograph specifies the desired particle size. Within any category of packings or phases listed below, there may be a wide range of columns available. Where it is necessary to define more specifically the chromatographic conditions, the individual monograph so indicates.]Change to read:PackingsL1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic silica rod.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 µm in diameter.L3—Porous silica particles, 3 USP31 to 10 µm in diameter, or a monolithic silica rod. USP31L4—Silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50µm in diameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core, 30 to 50 µm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 µm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod. USP31L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 3 to 10 µm in diameter.L9—Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 µm in diameter.L10—Nitrile groups chemically bonded to porous silica particles, 3 to 10 µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter.L12—A strong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core, 30 to 50 µm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diameter.L14—Silica gel having a chemically bonded, strongly basic quaternary ammoniumanion-exchange coating, 5 to 10 µm in diameter.L15—Hexylsilane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles, 5 to 10 µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the hydrogen form, 7 to 11 µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles, 3 to 10 µm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the calcium form, about 9 µm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 µm in diameter.L21—A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 µm in diameter.L22—A cation-exchange resin made of porous polystyrene gel with sulfonic acid groups, about 10 µm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups, about 10 µm in size.L24—A semi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface, 32 to 63 µm in diameter.[note—Available as YMC-Pack PVA-SIL manufactured by YMC Co., Ltd. and distributed by Waters Corp. ().]L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000 (as determined by polyethylene oxide), applied to neutral, anionic, and cationicwater-soluble polymers. A polymethacrylate resin base, cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups) was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter.L27—Porous silica particles, 30 to 50 µm in diameter.L28—A multifunctional support, which consists of a high purity, 100 , spherical silica substrate that has been bonded with anionic exchanger, amine functionality in addition to a conventional reversed phase C8 functionality.L29—Gamma alumina, reverse-phase, low carbon percentage by weight, alumina-based polybutadiene spherical particles, 5 µm in diameter with a pore volume of 80 .L30—Ethyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter.L31—A hydroxide-selective, strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5-µm macroporous particles having a pore size of 2000 and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene.L32—A chiral ligand-exchange packing–l-proline copper complex covalently bonded to irregularly shaped silica particles, 5 to 10 µm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of4,000 to 500,000 Da. It is spherical, silica-based, and processed to provide pH stability.[note—Available as TSKgel G4000 SWXL from Tosoh Biosep ().]L34—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the lead form, about 9 µm in diameter.L35—A zirconium-stabilized spherical silica packing with a hydrophilic (diol-type) molecular monolayer bonded phase having a pore size of 150 .L36—A 3,5-dinitrobenzoyl derivative of l-phenylglycine covalently bonded to 5-µm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of2,000 to 40,000 Da. It is a polymethacrylate gel.L38—A methacrylate-based size-exclusion packing for water-soluble samples.L39—A hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles, 5 to 20µm in diameter.L41—Immobilized 1-acid glycoprotein on spherical silica particles, 5 µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles, 5 µm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 5 to 10 µm in diameter.L44—A multifunctional support, which consists of a high purity, 60 , spherical silica substrate that has been bonded with a cationic exchanger, sulfonic acid functionality in addition to a conventional reversed phase C8 functionality.L45—Beta cyclodextrin bonded to porous silica particles, 5 to 10 µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads, about 10 µm in diameter.L47—High-capacity anion-exchange microporous substrate, fully functionalized with trimethlyamine groups, 8 µm in diameter.[note—Available as CarboPac MA1 and distributed by Dionex Corp. ().]L48—Sulfonated, cross-linked polystyrene with an outer layer of submicron, porous,anion-exchange microbeads, 15 µm in diameter.L49—A reversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles, 3 to 10 µm in diameter.[note—Available as Zirchrom PBD, manufactured by ZirChrom Separations, Inc., distributed by Alltech, .]L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities. The resin consists of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 µm in diameter, and a surface area not less than 350 m2 per g. Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.[note—Available as OmniPac PAX-500 and distributed by Dionex Corp. ().]L51—Amylose tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 5 to 10 µm in diameter.[note—Available as Chiralpak AD from Chiral Technologies, Inc., ().]L52—A strong cation-exchange resin made of porous silica with sulfopropyl groups, 5 to 10µm in diameter.[note—Available as TSK IC SW Cation from Tosoh Biosep ().]L53—Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 µm diameter. Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers. Capacity not less than 500 µEq/column.[note—Available as IonPac CS14 distributed by Dionex Corp. ().]L54—A size exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads, about 13 µm in diameter.[note—Available as Superdex Peptide HR 10/30 from Amersham Pharmacia Biotech ().]L55—A strong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer, about 5 µm in diameter.[note—Available as IC-Pak C M/D from Waters Corp. ().]L56—Propyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter.[note—Available as Zorbax SB-C3 from Agilent Technologies (/chem).]L57—A chiral-recognition protein, ovomucoid, chemically bonded to silica particles, about 5µm in diameter, with a pore size of 120 .[note—Available as Ultron ES-OVM from Agilent Technologies (/chem).]L58—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the sodium form, about 6 to 30 µm 1S (USP31) in diameter.[note—Available as Aminex HPX-87N from Bio-Rad Laboratories, (2000/01 catalog,#125-0143) .]L59—Packing having the capacity to separate proteins by molecular weight over the range of 10 to 500 kDa. It is spherical (10 µm), silica-based, and processed to provide hydrophilic characteristics and pH stability.[note—Available as TSKgel G3000SW Column (analytical column) and TSKgel Guard (guard column) from Tosoh Biosep (part numbers 05789 and 05371, respectively)().]L60—Spherical, porous silica gel, 10 µm or less in diameter, the surface of which has been covalently modified with alkyl amide groups and endcapped.[note—Available as Supelcosil ABZ from Supelco (/supelco).]L61—A hydroxide selective strong anion-exchange resin consisting of a highly cross-linked core of 13 µm microporous particles having a pore size less than 10 units and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene with a latex coating composed of 85 nm diameter microbeads bonded with alkanol quaternary ammonium ions (6%).[note—Available as Ion Pac AS-11 and AG-11 from Dionex ().]L62—C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter.L63— Glycopeptide teicoplanin linked through multiple covalent bonds to a 100- units spherical silica.[Note—Available as Chirobiotic T from Astec ().] 1S (USP31)美国药典(USP)规定的色谱柱编号见下面，是对应的色谱柱类型。
美国USP色谱柱编号对照表
美国USP色谱柱编号对照表L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称C18或ODSL2：30～50um表面多孔薄壳型键合C18(ODS)固定相L3：多孔硅胶微粒即一般的硅胶柱L4：30～50um表面多孔薄壳型硅胶L5：30～50um表面多孔薄壳型氧化铝L6：30～50um实心微球表面包覆磺化碳氟聚合物－强阳离子交换固定相L7：全多孔硅胶微粒键合C8官能团固定相简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相L10：多孔硅胶微球键合氰基固定相（CN）简称CN柱L11：键合苯基多孔硅胶微球固定相简称苯基柱L12：无孔微球键合季胺功能团的强阴离子填料L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1）简称C1柱L14:10um硅胶化学键合强碱性季铵盐阴离子交换固定相简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换树脂L18: 3～10um全多孔硅胶化学键合胺基（NH2）和氰基（CN）L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换树脂L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol）简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球L22：带有磺酸基团的多孔苯乙烯阳离子交换树脂L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换树脂L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相L27：30～50um的全多孔硅胶微粒L28：多功能载体，100?的高纯硅胶加以氨基键合以及C8反相键合的官能团L29: 氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5um，孔径80?L30: 全多孔硅胶键合乙基硅烷固定相L31: 季胺基改性孔径2000?的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33: 能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相,pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9um球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150?L36: 5um胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40,000Mw的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43: 硅胶微球键合五氟代苯基固定相L44: 多功能固定相,60 ?高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46: 季胺基改性苯乙烯-二乙烯基苯聚合物微球。
USP 42中色谱柱编号对应表
全多孔硅胶微粒键合C8官能团固定相
C8柱
L8
全多孔硅胶微粒键合非交联NH2固定相3 to 10 μm
NH2柱
L9
强酸性阳离子交换基团键合全多孔不规则形硅胶固定相
SCX柱
L10
多孔硅胶微球键合氰基固定相（CN）
CN柱
L11
键合苯基多孔硅胶微球固定相
苯基柱
L12
无孔微球键合季胺功能团的强阴离子交换柱
L25
聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。能分离分子量100～5000范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相
L26
丁基硅烷化学键合全多孔硅胶微球固定相
2.1×100mm,5μm
L27
30～50μm的全多孔硅胶微粒
L28
多功能载体，100Å的高纯硅胶加以氨基键合以及C8反相键合的官能团
美国药典(USP42)规定的色谱柱编号对应表
USP编号
填料/说明
简称
L1
十八烷基键合多孔硅胶或无机氧化物微粒固定相
ODS柱
L2
30～50μm表面多孔薄壳型键合十八烷基固定相
C18柱
L3
多孔硅胶微粒，即一般的硅胶柱
L4
30～50μm表面多孔薄壳型硅胶柱
L5
30～50μm表面多孔薄壳型氧化铝柱
L6
30～50μm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱
L29
氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5μm，孔径80Å
L30
全多孔硅胶键合乙基硅烷固定相
L31
季胺基改性孔径2000Å的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂
YMC色谱柱产品与美国药典USP色谱柱编号对应表
USP No. L1 十八烷基硅烷 官能团种类 YMC 色谱柱 YMC-Triart C18 YMC-Pack Pro C18 Hydrosphere C18 YMC-Pack Pro C18 RS YMC-Pack ODS-A YMC-Pack ODS-AM YMC-Pack ODS-AQ YMC-Pack ODS-AL J’sphere ODS-H80 J’sphere ODS-M80 J’sphere ODS-L80 L3 L7 多孔硅胶 辛烷基硅烷 YMC-Pack SIL YMC-Pack SIL-60 YMC-Triart C8 YMC-Pack Pro C8 YMC-Pack C8 L8 L10 L11 L13 L20 单分子层氨丙基硅烷 氰基/腈基 苯基 三甲基硅烷 二羟基丙基 YMC-Pack NH2 YMC-Pack CN YMC-Triart Phenyl YMC-Pack Ph YMC-Pack TMS YMC-Pack Diol-NP YMC-Pack Diol-60 YMC-Pack Diol-120 YMC-Pack Diol-200 YMC-Pack Diol-300 L24 L26 L40 L43 L45 L51 L62 乙烯基聚合物 丁烷基硅烷 纤维素-三（3,5-二甲基苯基氨基甲酸酯） 五氟苯基 β-环糊精 直链淀粉-三（3,5-二甲基苯基氨基甲酸酯） C30 硅烷 YMC-Pack PVA-Sil YMC-Pack Pro C4 YMC-Pack C4 新品已上市 YMC-Triart PFP YMC CHIRAL β-CD BR 新品已上市 YMC Carotenoid
戴安公司提供与美国药典(USP)规定的特殊色谱柱型号对应表
戴安公司色谱柱与美国药典（USP ）所规定的特殊色谱柱型号对应表
大家都知道美国药典（USP ）对色谱柱有专用的描述（编号从L1-LXX ），这与平时我们所熟悉的型号规格并不一致，例如大家所熟知的：“L1”是C18柱、“L7”是C8柱等等。
但用户在使用某些特殊的USP 柱时很难找到所对应的型号。
Dionex 公司在聚合物基质色谱柱研究及生产上具有丰富的经验，可提供多种USP 所描述的特殊规格色谱填料。
为了方便大家查询我们特作了一份对应表把一些特殊的色谱柱列出来供大家参考，以方便大家根据美国药典的要求选用。
USP 色谱填料名称Dionex 色谱柱型号
USP 所提到的某些用途 L12 IonPac ® S4A-SC Calcium Gluconate
L46 CarboPac ™ PA1 Fludeoxyglucose F 18 Injection Irbesartan (testing limit of azide)
Streptomycin Sulfate
L47 CarboPac MA1 Amikacin Kanamycin Sulfate
L48 IonPac AS5 Ferumoxides Injection (assay for citrate,
see Dionex Application Note 164)
Streptomycin Sulfate(CarboPac PA1) L50 OmniPac ® AX-500
L53 IonPac CS14 Bethanechol Chloride Injection (see Dionex Application Note 148)。
USP药典L1～L60对应色谱柱
下面分别是USPL1～L60的对映。
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter.L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter.L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating.L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter.L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating.L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter.L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10µm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size.L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter.L27—Porous silica particles,30to 50µm in diameter.L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality.L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å.L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached to acore of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter.L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å.L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel.L38—Amethacrylate-based size-exclusion packing for water-soluble samples.L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20µm in diameter.L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter.L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality.L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter.L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter.L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9L51—Amylose tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12 L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µmin diameter,with a pore size of 120Å.L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28。
美国药典色谱柱分类
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter. L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter. L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter. L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter. L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter. L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter. L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter. L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating. L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter. L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter. L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating. L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter. L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter. L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter. L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter. L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10µm in size. L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size. L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5 L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable. L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter. L27—Porous silica particles,30to 50µm in diameter. L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality. L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å. L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter. L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter. L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6 L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter. L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å. L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica. L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel. L38—Amethacrylate-based size-exclusion packing for water-soluble samples. L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silicaparticles,5to 20µm in diameter. L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter. L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter. L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality. L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter. L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7 L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter. L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8 L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists ofethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9 L51—Amylosetris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10 L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11 L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12 L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13 L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14 L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15 L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µm in diameter,with a pore size of 120Å. L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16 L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28 L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28L1是C18柱L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
USP药典L1～L60对应色谱柱
USP药典L1～L60对应色谱柱下面分别是USPL1～L60的对映。
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10μm in diameter.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50μm in diameter.L3—Porous silica particles,5to 10μm in diameter.L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50μm in di ameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50μm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50μm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles,3to 10μm in diameter.L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10μm in diameter.L9—10-μm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating.L10—Nitrile groups chemically bonded to porous silica particles,3to 10μm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10μm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to50μm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles,3to 10μm in diameter.L14—Silica gel 10μm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating.L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10μm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles,5to 10μm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the hydrogen form,7to 11μm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10μm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9μm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10μm in diameter.L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10μm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10μm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,abou t 10μm in size.L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrixsurface,32to 63μm in diameter.5L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles,5to 10μm in diameter.L27—Porous silica particles,30to 50μm in diameter.L28—Amultifunctional support,which consists of a high purity,100?,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality.L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5μm in diameter with a pore volume of 80?.L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10μm in diameter.L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached to acore of 8.5-μm macroporous particles having a pore size of 2000?and consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10μm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9μm in diameter.L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150?.L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-μm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel.L38—Amethacrylate-based size-exclusion packing for water-soluble samples.L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20μm in diameter.L41—Immobilized a1-acid glycoprotein on spherical silica particles,5μm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5μm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10μm in diameter.L44—Amultifunctional support,which consists of a high purity,60?,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality.L45—Beta cyclodextrin bonded to porous silica particles,5to 10μm in diameter.L46—Polystyrene/divinylbenzene substrate agglomeratedwith quaternary amine functionalized latex beads,10μm in diameter.L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8μm in diameter.7L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15μm in diameter.L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10μm in diameter.8L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15μm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9L51—Amylose tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10μm in diameter.10 L52—Astrong cation exchange resin made of porous silica with sulf opropyl groups,5to 10μm in diameter.11L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15μm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized mo nomers.Capacity not less than 500μEq/column.12L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13μm in diameter.13L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5μm in diameter.14L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10μm in diameter.15L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5μmin diameter,with a pore size of 120?.L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11μm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10μm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28L60—Spherical,porous silica gel,3or 5μm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6μmoles per m2.18USP28。
美国药典usp L1～L60对应色谱柱类型及型号
下面分别是USPL1～L60的对应。
L1—Octadecyl silane chemically bonded to porous silica or ceramic micro-particles,3to 10µm in diameter.L2—Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core,30to 50µm in diameter.L3—Porous silica particles,5to 10µm in diameter.L4—Silica gel of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L5—Alumina of controlled surface porosity bonded to a solid spherical core,30to 50µm in diameter.L6—Strong cation-exchange packing–sulfonated fluorocarbon polymer coated on a solid spherical core,30to 50µm in diameter.L7—Octylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L8—An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support,10µm in diameter.L9—10-µm irregular or spherical,totally porous silica gel having a chemically bonded,strongly acidic cation-exchange coating.L10—Nitrile groups chemically bonded to porous silica particles,3to 10µm in diameter.L11—Phenyl groups chemically bonded to porous silica particles,5to 10µm in diameter.L12—Astrong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core,30to 50µm in diameter.L13—Trimethylsilane chemically bonded to porous silica particles,3to 10µm in diameter.L14—Silica gel 10µm in diameter having a chemically bonded,strongly basic quaternary ammonium anion-exchange coating.L15—Hexylsilane chemically bonded to totally porous silica particles,3to 10µm in diameter.L16—Dimethylsilane chemically bonded to porous silica particles,5to 10µm in diameter.L17—Strong cation-exchange resin consisting of sulfonated cross-linkedstyrene-divinylbenzene copolymer in the hydrogen form,7to 11µm in diameter.L18—Amino and cyano groups chemically bonded to porous silica particles,3to 10µm in diameter.L19—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form,about 9µm in diameter.L20—Dihydroxypropane groups chemically bonded to porous silica particles,5to 10µm in diameter.L21—Arigid,spherical styrene-divinylbenzene copolymer,5to 10µm in diameter.L22—Acation-exchange resin made of porous polystyrene gel with sulfonic acid groups,about 10µm in size.L23—An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups,about 10µm in size.L24—Asemi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface,32to 63µm in diameter.5L25—Packing having the capacity to separate compounds with a molecular weight range from 100–5000(as determined by polyethylene oxide),applied to neutral,anionic,and cationic water-soluble polymers.Apolymethacrylate resin base,cross-linked with polyhydroxylated ether (surface contained some residual carboxyl functional groups)was found suitable.L26—Butyl silane chemically bonded to totally porous silica particles,5to 10µm in diameter.L27—Porous silica particles,30to 50µm in diameter.L28—Amultifunctional support,which consists of a high purity,100Å,spherical silica substrate that has been bonded with anionic exchanger,amine functionality in addition to a conventional reversed phase C8functionality.L29—Gamma alumina,reverse-phase,low carbon percentage by weight,alumina-based polybutadiene spherical particles,5µm in diameter with a pore volume of 80Å.L30—Ethyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.L31—Astrong anion-exchange resin-quaternary amine bonded on latex particles attached to acore of 8.5-µm macroporous particles having a pore size of 2000Åand consisting of ethylvinylbenzene cross-linked with 55%divinylbenzene.L32—Achiral ligand-exchange packing–L-proline copper complex covalently bonded to irregularly shaped silica particles,5to 10µm in diameter.L33—Packing having the capacity to separate dextrans by molecular size over a range of 4,000to 500,000Da.It is spherical,silica-based,and processed to provide pHstability.6L34—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form,about 9µm in diameter.L35—Azirconium-stabilized spherical silica packing with a hydrophilic (diol-type)molecular monolayer bonded phase having a pore size of 150Å.L36—A3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5-µm aminopropyl silica.L37—Packing having the capacity to separate proteins by molecular size over a range of 2,000to 40,000Da.It is a polymethacrylate gel.L38—Amethacrylate-based size-exclusion packing for water-soluble samples.L39—Ahydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40—Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5to 20µm in diameter.L41—Immobilized a1-acid glycoprotein on spherical silica particles,5µm in diameter.L42—Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5µm in diameter.L43—Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,5to 10µm in diameter.L44—Amultifunctional support,which consists of a high purity,60Å,spherical silica substrate that has been bonded with a cationic exchanger,sulfonic acid functionality in addition to a conventional reversed phase C8functionality.L45—Beta cyclodextrin bonded to porous silica particles,5to 10µm in diameter.L46—Polystyrene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads,10µm in diameter.L47—High-capacity anion-exchange microporous substrate,fully functionalized with trimethlyamine groups,8µm in diameter.7L48—Sulfonated,cross-linked polystyrene with an outer layer of submicron,porous,anion-exchange microbeads,15µm in diameter.L49—Areversed-phase packing made by coating a thin layer of polybutadiene onto spherical porous zirconia particles,3to 10µm in diameter.8L50—Multifunction resin with reversed-phase retention and strong anion-exchange functionalities.The resin consists of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm in diameter,and a surface area not less than 350m2per g.Substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.9L51—Amylose tris-3,5-dimethylphenylcarbamate-coated,porous,spherical,silica particles,5to 10µm in diameter.10L52—Astrong cation exchange resin made of porous silica with sulfopropyl groups,5to 10µm in diameter.11L53—Weak cation-exchange resin consisting of ethylvinylbenzene,55%cross-linked with divinylbenzene copolymer,3to 15µm diameter.Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers.Capacity not less than 500µEq/column.12 L54—Asize exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads,about 13µm in diameter.13L55—Astrong cation-exchange resin made of porous silica coated with polybutadiene–maleic acid copolymer,about 5µm in diameter.14L56—Isopropyl silane chemically bonded to totally porous silica particles,3to 10µm in diameter.15L57—Achiral-recognition protein,ovomucoid,chemically bonded to silica particles,about 5µmin diameter,with a pore size of 120Å.L58—Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the sodium form,about 7to 11µm in diameter.16L59—Packing having the capacity to separate proteins by molecular weight over the range of 10to 500kDa.It is spherical (10µm),silica-based,and processed to provide hydrophilic characteristics and pHstability.17USP28L60—Spherical,porous silica gel,3or 5µm in diameter,the surface of which has been covalently modified with palmitamidopropyl groups and endcapped with acetamidopropyl groups to a ligand density of about 6µmoles per m2.18USP28。
美国药典规定色谱柱类型
L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW 范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：30～50mm的全多孔硅胶微粒L28：多功能载体，100Å的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5mm，孔径80ÅL30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000Å的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相, pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150ÅL36:5mm胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40000MW的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60 Å高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，3-10u。
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L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：30～50mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：30～50mm表面多孔薄壳型硅胶柱L5：30～50mm表面多孔薄壳型氧化铝柱L6：30～50mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：3～10mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯－二乙烯基苯共聚物，强阳离子交换柱L20：二羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯－二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。
能分离分子量100～5000MW 范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：30～50mm的全多孔硅胶微粒L28：多功能载体，100Å的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5mm，孔径80ÅL30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000Å的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量4000～40000MW范围蛋白质分子的球形硅胶固定相, pH稳定性好L34：铅型磺化交联苯乙烯－二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150ÅL36:5mm胺丙基硅胶键合L-苯基氨基乙酸－3,5二硝基苯甲酰L37：适合分离分子量2000～40000MW的聚甲基丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5－二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定α1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60 Å高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: β-环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷化学键合于多孔硅胶或陶瓷微粒，3-10u。
L2 Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 μm in diameter.L2 十八烷基键合硅烷化学键合于表面空隙率一定的键合在紧密球核上的硅胶，粒径30-50u。
L3 Porous silica particles, 5 to 10 μm in diameter.L3 多孔硅胶颗粒，粒径5-10u。
L4 Silica gel of controlled surface porosity bonded to a solid spherical core,30 to 50 μm in diameter.L4 表面空隙率一定的硅胶键合于紧密球核上，粒径30-50u。
L5 Alumina of controlled surface porosity bonded to a solid spherical core,30 to 50 μm in diameter.L5 表面空隙率一定的氧化铝键合于紧密球核上，粒径30-50u。
L6 Strong cation-exchange packing: sulfonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 μm in diameter.L6 强阳离子交换填料：磺化氟代烃聚合物涂渍于紧密球核上，粒径30-50u。
L7 Octyl silane chemically bonded to totally porous silica particles, 1.5 t o 10 μm in diameter.L7 辛基硅烷化学键合于完全多孔硅胶担体，粒径10u。
L8 An essentially monomolecular layer of aminopropyl-silane chemically bonded to totally porous silica gel support, 3 to 10 μm in diameter.L8 氨丙基硅烷单分子层化学键合于完全多孔硅胶担体，粒径10u。
L9 Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic ation-exchange coating, 3 to 10 μm in diameter.L9 10u不规则的完全多孔硅胶具有化学键合的强酸性阳离子交换涂层。
L10 Nitrile groups chemically bonded to porous silica particles, 3 to 10 μm in diameter.L10 氰基团化学键合于多孔微粒硅，粒径3-10u。
L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 μm in diameter.L11 苯基化学键合于多孔微粒硅，粒径3-10u。
L12 Strong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core, 30 to 50 μm in diame terL12 由四元胺化学键合于精密硅球核形成的强阴离子交换填料，粒径30-50u。
L13 Trimethylsilane chemically bonded to porous silica particles,3 to 10 μm in diameter.L13 三甲基硅烷化学键合于完全多孔硅胶，粒径3-10u。
L14 Silica gel having a chemically bonded, strongly basic quaternary ammonium anion-exchange coating, 5 to 10 μm in diameter.L14 具有强碱性四元胺阴离子交换涂层的10u硅胶化学键合相。
L15 Hexyl silane chemically bonded to totally porous silica particles,3 to 10 μm in diameter.L15 己基硅烷化学键合于完全多孔性微粒硅，粒径3-10u。
L16 Dimethyl silane chemically bonded to totally porous silica par ticles, 5 to 10 μm in diameter.L16 二甲基硅烷化学键合于完全多孔性微粒硅，粒径3-10u。
L17 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 7 to 11 μm in diameter.L17 由磺化的苯乙烯-二乙烯基苯交连共聚物组成的氢型阳离子交换树脂，粒径7-11u。
L18 Amino and cyano groups chemically bonded to porous silica particles,3 to 10 μm in diameter.L18 氨基和氰基化学键合于多孔微粒硅，粒径3-10u。
L19 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 9 μm in diameter.L19 由磺化的苯乙烯-二乙烯基苯交连共聚物组成的钙型阳离子交换树脂，粒径7-11u。
L20 Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 μm in diameter.L20 二甲氧基丙烷基化学键合于多孔硅胶微粒，粒径5-10u。
L21 A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 μm in diameter.L21 刚性球形苯乙烯-二乙烯基苯共聚物，粒径5-10u。
L22 A cation exchange resin made of porous polystyrene gel with sulfonic acid groups, about 10 μm in size.L22 由多孔聚苯乙烯凝胶和磺酸基组成的阳离子交换树脂，粒径约为10u。