Self-reported participation restrictions in normal

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Journal of Otology

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Self-reported participation restrictions in normal hearing individuals in

thyroid ontogeny:Evidence of subclinical changes

Caio Leônidas Oliveira de Andrade a,b,∗,Gabriela Carvalho Machado a,

Luan Paulo Franco Magalhães b,Elen Pereira de Jesus c,Elaine Alves Matias b,

Taíse Lima de Oliveira Cerqueira d,Hélida Braga de Oliveira a,Luciene da Cruz Fernandes e,

Helton Estrela Ramos f,Crésio de Aragão Dantas Alves g

a Postgraduate Program in Interactive Processes of Organs and Systems,Institute of Health Science–Federal University of Bahia,Avenue Rector Miguel Calmon,Valley of

Canela,40110100,Salvador,Bahia,Brazil

b Department of Life Sciences,University of the State of Bahia,Street Silveira Martins,Cabula,41150000,Salvador,Bahia,Brazil

c Social Services Sister Dulce,Avenue Bonfim,40420415,Salvador,Bahia,Brazil

d Institut

e o

f Health Science–Federal University of Bahia,Avenue Rector Miguel Calmon,Valley of Canela,40110100,Salvador,Bahia,Brazil

e Department o

f Speech Therapy,Institute of Health Science–Federal University of Bahia,Avenue Rector Miguel Calmon,Valley of Canela,40110100,Salvador,Bahia,

Brazil

f Department of Bioregulation,Health&Sciences Institute,Federal University Bahia(UFBA),Brazil

g Medical School,Institute of Health Science–Federal University of Bahia,Avenue Rector Miguel Calmon,Valley of Canela,40110100,Salvador,Bahia,Brazil

A R T I C L E I N F O

Keywords:

Hearing

Hearing loss

Auditory perception

Congenital hypothyroidism

Surveys and questionnaires

A B S T R A C T

Purpose:To verify evidence of subclinical alterations through self-reported participation restrictions in normal

hearing individuals and congenital hypothyroidism patients.

Methods:An analytical,quantitative,cross-sectional exploratory study with a1:1ratio,consisting of a con-

venience sample of86normal hearing individuals with(n=42)and without(n=44)congenital hypothyr-

oidism diagnosis.All participants underwent tonal and speech audiometry,immitance and distortion product

otoacoustic emissions.The researchers excluded people with hearing loss,genetic syndromes and metabolic

diseases.The instrument used for evaluate of self-reported participation restrictions was the HHIE-adapted

questionnaire,composed of25questions,12of which were social domain and13emotional domain.Student's t-

test and chi-square test were used for statistical analysis at a significance level of5%.

Results:There was a significant(p<0.001)self-reported participation restrictions in CH(61.9%),with a

greater relevance for the social domain(p=0.002).There was a greater frequency of mild/moderate(40.5%)

and higher prevalence of association with clinical factors and adherence to treatment.

Conclusion:Thefindings indicate that self-reported participation restrictions in normal hearing individuals with

congenital hypothyroidism was more significant than in the non-exposed group,suggesting evidence of sub-

clinical auditory abnormalities in this population.

1.Introduction

The close dependence of adequate levels of thyroid hormones for

the normal development of the auditory system is already well dis-

cussed(Sohmer and Freeman,1996;Sininger et al.,1997;Hashemipour

et al.,2012),both in the pre-and postnatal moments,especially in the

period known as critical for auditory maturation that begins at the end

of thefirst trimester of gestation and lasts until thefirst year of life

(Sininger et al.,1997),which explains the association of hearing

changes in congenital hypothyroidism(CH),even in cases with diag-

nosis and early treatment³.

Currently,with the early diagnosis and treatment of CH,hearing

abnormalities do not coexist as frequently and severely as before the

advent of Neonatal Screening Programs(NSP)(Rovet et al.,1996;

https:///10.1016/j.joto.2018.11.007

Received29August2018;Received in revised form10November2018;Accepted19November2018

Peer review under responsibility of PLA General Hospital Department of Otolaryngology Head and Neck Surgery.

∗Corresponding author.Avenue Rector Miguel Calmon,Valley of Canela,40110100,Salvador,Bahia,Brazil.

E-mail addresses:caioleonidas@(C.L.O.de Andrade),gmachado.fono@(G.C.Machado),m.agalhaes@(L.P.F.Magalhães), elenpj1@(E.Pereira de Jesus),lanealves@(E.Alves Matias),taisellima@(T.L.de Oliveira Cerqueira),

helidaboliveira@(H.B.de Oliveira),luenefrenandes@(L.da Cruz Fernandes),cresio.alves@.br(C.de Aragão Dantas Alves).

Journal of Otology 14 (2019) 6–11

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