连续性血液净化治疗危重病合并高钾血症的临床探讨

连续性血液净化治疗危重病合并高钾血症的临床探讨
邱昌建
【期刊名称】《海南医学》
【年(卷),期】2011(22)20
【摘要】目的探讨连续性血液净化(CRRT)治疗危重病合并高钾血症的方法及效果，为临床治疗提供参考。

方法本院2010年4月至2011年4月收治入院的110例
危重病合并高钾血症患者随机分成两组，对照组55例，行内科综合治疗；实验组55例，在内科综合治疗的基础上行连续性血液净化治疗。

随访10～40 d，比较两组患者的血钾下降情况，同时对两组患者治疗后各项生化指标变化进行比较分析。

结果随访期间两组相比，实验组患者的平均血钾浓度为(4.77±0.83)mmol/L，低
于对照组的（5.86±0.91）nmmol/IL，差异有统计学意义(P＜0.05)。

治疗后两组内相比，两组各项生化指标均优于治疗前，差异有统计学意义(P＜0.05)；治疗后
两组间相比，实验组的患者各项生化指标均优于对照组，差异有统计学意义(P＜0.05)。

结论应用连续性血液净化早期治疗危重病合并高钾血症，可以有效地降低患者血钾至5.5 mmol/IL以下的正常水平，治疗后显著改善其各项生化指标，是
一种行之有效的治疗方法，应当在临床中推广使用。

%Objective To investigate the effect of continuous blood purification (CRRT) in critically ill patients complicated with hyperkalemia, and to provide a reference for clinical treatment. Methods A retrospective analysis was conducted on 110 critically ill patients complicated with hyperkalemia admitted in our hospital fromApril 2010 to April 2011. The patients were randomly divided into the study group and the control group, each with 55 cases..Patients in
the control group received comprehensive medical treatment, while those in the study group were treated by continuous blood purification on the basis of comprehensive medical treatment. All the patients were followed up for 10～40 days. The decline in serum potassium and the changes in biochemical indicators in the two groups were compared. Results During the follow-up, the average concentration of serum potassium in the study group was (4.77 ± 0.83) mmol/L, which is significantly lower than
(5.86±0.91) mmol/L in the control group (P<0.05). After tr eatment, the biochemical indicators in both groups are significantly better than those before treatment (P＜0.05), but the improvement in the study group was significantly superior (P＜0.05). Conclusion For critically ill patients complicated with hyperkalemia, continuous blood purification therapy can effectively reduce serum potassium to the level below normal (5.5 mmol/L), and can significantly improve the biochemical indicators. It is a quite effective method that should be extended in clinical practice.
【总页数】3页(P24-26)
【作者】邱昌建
【作者单位】武汉大学人民医院肾内科，湖北武汉 430060
【正文语种】中文
【中图分类】R589.4
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