川崎病并发冠脉病变患儿血浆ET-1和血清 Hcy、cTnI检测的临床意义

川崎病并发冠脉病变患儿血浆ET-1和血清 Hcy、cTnI检测
的临床意义
李鹏飞
【期刊名称】《放射免疫学杂志》
【年(卷),期】2012(025)005
【摘要】Objective To explore the clinical significance of changes of plasma ET-1 and serum Hcy, cTnI levels in pediatric paients with Kawasaki diseases complicated with coronary artery disorder. Methods Plasma ET-1 (with RIA) and serum Hcy (with immune method) , serum cTnI (with Biochemistry) levels were measured in 31 patients with Kawasaki diseases complicated with coronary artery dissrder and 35 normal controls. Results Plasma ET-1 and serum Hcy,cTnI levels were significantly higher than those in controls (P<0.01) . Plasma ET-1 levels were positive correlative with serum Hey,cTnI levels(r =0.4782,0.5014,P <0.01). Conclusion Detection of plasma ET-1 and serum Hcy.cTnl levels were closely related to the diseases process and possess important clinical values.%目的:探讨了川崎病并发冠脉病变患儿血浆ET-1和血清Hcy、cTnI检测的变化及临床意义.方法:应用放免法、免疫结合和生化法对31例川崎病并发冠脉病变患儿进行了血浆ET-1和血清Hcy、cTnI测定,并与35例正常儿童作比较.结果:川崎病并发冠脉病变患儿血浆ET-1和血清Hcy、cTnI水平均显著地高于正常儿组(P<0.01),且血浆ET-1和血清Hcy、cTnI水平呈正相关(r=0.4782、0.5014,P<0.01).结论:检测川崎病并发冠脉病变患儿血浆ET-1和血清Hcy、cTnI水平的变化对疾病的发生和发展及预后均有重要的临床价值.
【总页数】2页(P499-500)
【作者】李鹏飞
【作者单位】江苏省连云港市第一人民医院儿科,222002
【正文语种】中文
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