透明质酸钠凝胶对宫腔镜宫腔粘连患者术后再粘连的预防效果

透明质酸钠凝胶对宫腔镜宫腔粘连患者术后再粘连的预防效果苏峻;陈志琴;姜健慧
【期刊名称】《中国生化药物杂志》
【年(卷),期】2017(037)001
【摘要】Objective To investigate the Preventive effect of sodium hyaluronate gel on postoperative adhesion of hysteroscopic intrauterine adhesions. Methods 84 cases of IUA patients undergoing hysteroscopy were retrospectively selected,and divided into two groups according to the different ways of prevention and control of IUA,42 cases in each group.The control group was treated with Foley balloon catheter after operation,the study group was treated with sodium hyaluronate gel prevention on the based of control group.The clinical signs of the patients before and after treatment one,two and three months were observed,the therapeutic effects and complication were compared between two groups. Results After treatment one,two and three months,the adhesion type score and the score scale of study group, were significantly decreased,and lower than the control group,the difference was statistically significant (P<0.05).The total effective rate of the study group was 90.48%,which was significantly higher than that of the control group (83.33%),the difference was statistically significant (P<0.05).In the course of treatment,the complication rate of the two groups was 11.90% (5/42),there was no significant difference between the two groups in the incidence of complications.
Conclusion Hyaluronic acid sodium gel on hysteroscopic intrauterine adhesions in patients with postoperative adhesions have a significant preventive effect,can improve the treatment efficiency and clinical signs,and with high security.%目的探讨透明质酸钠凝胶对宫腔镜宫腔粘连(intrauterine adhesion,IUA)患者术后再粘连的防控效果观察.方法回顾性选择台州市第一医院接诊的宫腔粘连患者84例,根据预防控制IUA方式的不同分为2组,各42例.对照组采用术后放置Foley球囊导尿管的预防措施,研究组在对照组基础上加用透明质酸钠凝胶预防,观察2组治疗前及治疗1、2、3个月后患者临床体征,比较2组治疗效果和并发症情况.结果治疗1、2、3个月后,研究组粘连类型评分和累及范围评分均显著降低,且低于对照组,差异具有统计学意义(P<0.05).对照组治疗总有效率为83.33%,研究组总有效率为90.48%,研究组显著高于对照组,差异具有统计学意义(P<0.05).治疗过程中,2组并发症发生率均为11.90%(5/42),2组并发症发生率比较差异无统计学意义.结论透明质酸钠凝胶对宫腔镜宫腔粘连患者术后再粘连的预防效果显著,能提高治疗有效率,改善临床体征,且安全性高.
【总页数】3页(P142-144)
【作者】苏峻;陈志琴;姜健慧
【作者单位】台州市第一医院妇产科,浙江台州 318020;台州市第一医院妇产科,浙江台州 318020;台州市第一医院妇产科,浙江台州 318020
【正文语种】中文
【中图分类】R473.71
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