Tobramycin_DataSheet_MedChemExpress
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Inhibitors, Agonists, Screening Libraries
Data Sheet
BIOLOGICAL ACTIVITY:
Tobramycin is an aminoglycoside, broad–spectrum antibiotic produced by Streptomyces tenebrarius.
Target: Antibacterial
Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram–negative infections. It is especially effective against species of Pseudomonas [1].
Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result,mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration. From Wikipedia [2].
References:
[1]. http://www.toku–/Upload/Products/PDS/20120515001224.pdf
[2]. /wiki/Tobramycin
Product Name:
Tobramycin Cat. No.:
HY-B0441CAS No.:
32986-56-4Molecular Formula:
C 18H 37N 5O 9Molecular Weight:
467.51Target:
Bacterial Pathway:
Anti–infection Solubility:H 2
O: ≥ 200 mg/mL
Caution: Product has not been fully validated for medical applications. For research use only.
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