大豆异黄酮治疗绝经后骨质疏松症的临床研究

大豆异黄酮治疗绝经后骨质疏松症的临床研究
王玮;曾亚奇;毕珣
【期刊名称】《武警医学》
【年(卷),期】2011(22)9
【摘要】Objective To study the effect of soy bean isoflavones (SI) on treating menopausal female patients with osteoporosis. Methods Sixty inpatients with osteoporosis were divided into study group and control group at random, each consisting of 30 patients. The study group was treated with SI while the control group was treated with calcium gluconate plus vitamin D. All the patients underwent blood serum biochemistry test and were assessed with a subjective clinical effectiveness questionnaire. Results Both the biochemical variables, including calcium, AIJP, and assessment of clinical effectiveness were statistically better in the study group than that in the control group (P <0.05). Conclusions SI is an ideal and reliable agent for clinical intervention of menopausal female patients with osteoporosis, which deserves wide clinical application.%目的了解大豆异黄酮对于绝经后骨质疏松症的治疗作用.方法选取绝经后骨质疏松症患者60例,随机分为研究组和对照组,每组30名.研究组予以大豆异黄酮治疗,对照组应用葡萄糖酸钙加维生素D治疗；效果评定选用血清生化指标和临床疗效评定两方面.结果治疗6个月后,研究组血清钙(Ca)、碱性磷酸酶(AIJP)治疗前后差值与对照组比较显著提高,差异有统计学意义(P＜0.01)；临床疗效评价研究组的显效率高于对照组(P
＜0.05).研究组骨密度值较治疗前提高(P＜0.01),对照组较治疗前无明显改变(P＞0.05).结论大豆异黄酮治疗绝经后骨质疏松症临床疗效确切,值得推广应用.
【总页数】3页(P747-749)
【作者】王玮;曾亚奇;毕珣
【作者单位】300162天津,武警医学院附属医院营养科;300162天津,武警医学院附属医院营养科;300162天津,武警医学院附属医院营养科
【正文语种】中文
【中图分类】R151.3
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