Chinese CONSORT Flow Diagram

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RCT临床研究遵循CONSORT规范

RCT临床研究遵循CONSORT规范
?
Blinding 盲法
11a
If done, who was blinded after assignment to interventions (for example, participants, care providers, those assessing outcomes) and how
需要明确临床试验分析,按ITT人群,还是PP人群,还是全分析集,都需要明确
?
Outcomes and estimation 结局
17a
For each primary and secondary outcome, results for each group, and the estimated effect size and its precision (such as 95% confidence interval)
若使用了盲法,需指明谁是干预的被盲者(例如受试者、干预给予者、结果评价者)以及如何设盲
?
11b
If relevant, description of the similarity of interventions
如若涉及,描述每组干预的相似性
?
Statistical methods 统计方法
12a
Statistical methods used to compare groups for primary and secondary outcomes
RCT临床研究遵循CONSORT规范(中文版)
位置
编号
项目说明
页码
附例
Title and abstract
?
1a
题目中说明研究的性质,如随机对照双盲研究
?
1b

如何向SCI生物医学期刊投稿

如何向SCI生物医学期刊投稿
and Discussion(讨论): What does it mean?
1.文题 (title)
Most important part of the paper To attract readers
Content of Titles
• Independent variable (s) Dependent variable (s) Who or what was studied Circumstances of data collection Research design
Methods
• Chronological order • Avoid trade name or proprietary name • Human subjects: IRB
informed consent • Statistical analyses
CONSORT 2010 Flow Diagram
3.摘要(abstract)
Most important part of a biomedical article, after the title For readers For the reviewers
Types of Abstracts
Publication abstracts - Unstructured abstract descriptive
Analysed (n= ) Excluded from analysis (give reasons) (n= )
Analysis
Analysed (n= ) Excluded from analysis (give reasons) (n= )
6.结果(results)
FUNCTIONS To tell what happened during the study To present the findings (data) of the study To explain any changes from the study as planned

雅思写作流程图Flow chart课件

雅思写作流程图Flow chart课件

Flow chart = process diagram一、流程图的特点1. 描绘某一事物的发展或运作过程2. 遵循某种顺序3. 图中会标出原材料的名称和步骤的细节4. 一般会出现一些专业生词5. 流程最终要达成某种目的或结果二、流程图的写作步骤1. 读题目,确定描述什么?目的或结果?2. 找信息,定步骤所有的信息点,包括图中所有有文字的地方,或所有表示动作或变化的图示(所有的时间、大小、距离等数字信息)1.定框架,写文章第一段:介绍流程图是做什么的。

第二段:详细介绍原料与准备、每一步的变化、过程及结果。

第三段:简单总结2.读文章,做检查单词拼写、语法、替换重复的词汇等。

三.流程图常用的表达1. The flow chart illustrates the recycling process of _____.2. The process of ____ involves the following steps.3. The whole procedure of ___ can be categorised into ____ stages.4. The row materials for ____ include ___, ___ and ____.5. The first step is to ______.6. ____ with ____ is prepared to _____.7. ____ is used as ____ of ____.8. _____ is mixed with ____ to produce _____.9. _____ can change into ____, when ____.10. The process of ____ is really a simple(complicated) process.The pictures below show the recycling process of wasted glass bottles.As is displayed in the flow chart, the recycling process of glass is really a complex one.The overall process can be categorised=classified=divided into three stages.First, glass products in various forms are gathered=assembled in the Collection point, so that they are easily transported by special trucks or vans to the Cleaning plant, where they get sterilisation byhigh-pressured water. There are three different channels in the Recycling plant, namely Brown, Green and Clear, which represent the colors of glass. After recycled in the furnace, glass products are melted=forged into recycled liquid glass. Mixed with new liquid glass, the compound is finally moulded into solid glass, which, afterwards, will be sent to various customer supermarkets for selling. Thus, the glass will go to the customers for different purposes.Through a brief introduction of the circle of glass recycling, we come to realize that recycling plays a vital role in environmental protection and ecological preservation.The diagram below describes how to recycle organic waste to produce compost(fertilizer).1. The flow chart illustrates the recycling process of organic waste to produce fertilizer.As is clearly shown in the picture, thefirst step is to find a plastic container of two cubic metres and stab several holes on its body so that air could fill in. Secondly, a 15cm thick layer of food is placed at the bottom of the container and grass is put just above the layer for the same height with some news paper covered on the very top. After that, some nitrogen and water are added into the container, and the water should only be hot. Finally, the container is sealed up and the external heat would help the formation of the compost. After six months, when the fertilizer is ready, all we have to do is to pour it into garden soil to nourish plants and flowers.Generally speaking, making garden fertilizer in this way is easy to operate but it costs much time.2. The flow chart shows the wholeprocess of producing fertilizer by recycling organic waste.Firstly, a two cubic metres plastic container is prepared, with some air holes on its body. Secondly, some organic waste is put into the plastic container. The organic waste includes news paper, grass and food. The right order of adding them is putting food in the bottom 15cm of the container and grass in the middle 15cm upon food. News paper is on the very top. Then nitrogen and water are added into the container. What should be noticed is that water can only be hot water. The next step is to seal up and heat the container. After six months, compost is produced. So we can use them to fertilize the garden.As can be seen from the picture, it isusually simple to change organic waste into fertilizer used to water flowers and trees in the garden.3. The information provided in the diagram is about how to use organic waste to produce compost in the following several simple stages.The first stage is to prepare a plastic container, two cubic metres in volume, with some ventilation holes on the side. Then organic waste such as leaves, pieces of paper and residues can be placed into the container so that three layers (each 15 cm) can be formed in the bottom---news paper, grass and food respectively from up to down. The next important step is to add nitrogen into it and then pour hot water only in to mix together. What is remembered to do next is that the container needs to besealed and heated. As a result, the vapor can be emitted through the holes located on its body. After that it takes roughly six months to convert into composts and then they are ready for fertilizing plants and flowers in the garden.。

最新雅思写作流程图Flow-chart讲义

最新雅思写作流程图Flow-chart讲义

Flow chart = process diagram一、流程图的特点1. 描绘某一事物的发展或运作过程2. 遵循某种顺序3. 图中会标出原材料的名称和步骤的细节4. 一般会出现一些专业生词5. 流程最终要达成某种目的或结果二、流程图的写作步骤1. 读题目,确定描述什么?目的或结果?2. 找信息,定步骤所有的信息点,包括图中所有有文字的地方,或所有表示动作或变化的图示(所有的时间、大小、距离等数字信息)1.定框架,写文章第一段:介绍流程图是做什么的。

第二段:详细介绍原料与准备、每一步的变化、过程及结果。

第三段:简单总结2.读文章,做检查单词拼写、语法、替换重复的词汇等。

三.流程图常用的表达1. The flow chart illustrates the recycling process of _____.2. The process of ____ involves the following steps.3. The whole procedure of ___ can be categorised into ____ stages.4. The row materials for ____ include ___, ___ and ____.5. The first step is to ______.6. ____ with ____ is prepared to _____.7. ____ is used as ____ of ____.8. _____ is mixed with ____ to produce _____.9. _____ can change into ____, when ____.10. The process of ____ is really a simple(complicated) process.The pictures below show the recycling process of wasted glass bottles.As is displayed in the flow chart, the recycling process of glass is really a complex one.The overall process can be categorised=classified=divided into three stages.First, glass products in various forms are gathered=assembled in the Collection point, so that they are easily transported by special trucks or vans to the Cleaning plant, where they get sterilisation byhigh-pressured water. There are three different channels in the Recycling plant, namely Brown, Green and Clear, which represent the colors of glass. After recycled in the furnace, glass products are melted=forged into recycled liquid glass. Mixed with new liquid glass, the compound is finally moulded into solid glass, which, afterwards, will be sent to various customer supermarkets for selling. Thus, the glass will go to the customers for different purposes.Through a brief introduction of the circle of glass recycling, we come to realize that recycling plays a vital role inenvironmental protection and ecological preservation.The diagram below describes how to recycle organic waste to produce compost(fertilizer).1. The flow chart illustrates the recycling process of organic waste toproduce fertilizer.As is clearly shown in the picture, the first step is to find a plastic container of two cubic metres and stab several holes on its body so that air could fill in. Secondly, a 15cm thick layer of food is placed at the bottom of the container and grass is put just above the layer for the same height with some news paper covered on the very top. After that, some nitrogen and water are added into the container, and the water should only be hot. Finally, the container is sealed up and the external heat would help the formation of the compost. After six months, when the fertilizer is ready, all we have to do is to pour it into garden soil to nourish plants and flowers.Generally speaking, making garden fertilizer in this way is easy to operate but it costs much time.2. The flow chart shows the whole process of producing fertilizer by recycling organic waste.Firstly, a two cubic metres plastic container is prepared, with some air holes on its body. Secondly, some organic waste is put into the plastic container. The organic waste includes news paper, grass and food. The right order of adding them is putting food in the bottom 15cm of the container and grass in the middle 15cm upon food. News paper is on the very top. Then nitrogen and water are added into the container. What should be noticed isthat water can only be hot water. The next step is to seal up and heat the container. After six months, compost is produced. So we can use them to fertilize the garden.As can be seen from the picture, it is usually simple to change organic waste into fertilizer used to water flowers and trees in the garden.3. The information provided in the diagram is about how to use organic waste to produce compost in the following several simple stages.The first stage is to prepare a plastic container, two cubic metres in volume, with some ventilation holes on the side.Then organic waste such as leaves, pieces of paper and residues can be placed into the container so that three layers (each 15 cm) can be formed in the bottom---news paper, grass and food respectively from up to down. The next important step is to add nitrogen into it and then pour hot water only in to mix together. What is remembered to do next is that the container needs to be sealed and heated. As a result, the vapor can be emitted through the holes located on its body. After that it takes roughly six months to convert into composts and then they are ready for fertilizing plants and flowers in the garden.。

雅思写作小作文范文 雅思写作流程图flow chart 消费品制造过程.doc

雅思写作小作文范文 雅思写作流程图flow chart 消费品制造过程.doc

雅思写作小作文范文雅思写作流程图flow chart 消费品制造过程今天我们雅思写作小作文范文的文章来研究下流程图flow chart。

该图表十分复杂,不仅包含产品的制造阶段,而且还说明了各个阶段的反馈。

因此很容易梳理不清楚,导致无从下笔。

其实我们完全可以将这两部分分开。

一个自然段只说制作过程,一个自然段只说反馈。

小编搜集了一篇相应的高分范文,以供大家参考。

雅思写作小作文题目The diagram below shows the typical stages of consumer goods manufacturing, including the process by which information is fed back to earlier stages to enable adjustment.Summarise the information by selecting and reporting the main features, and make comparisons where relevant.雅思写作小作文范文The provided flowchart illustrates the process of consumer goods production in an orderly manner and includes various stages of production and sales together with the feedback supplied towards the earlier stages which allows improvements and modifications throughout the process.上面所给出的流程图按顺序描述了消费物品生产的过程,并且包括生产和消费的各个阶段,以及回馈给最初阶段的反馈。

这使得整体过程的提升和修改成为可能。

傅阳小作文——流程图

傅阳小作文——流程图
第十八页,共40页。
• This diagram shows the constituent parts of a cell and how the genetic information within a cell, which is stored in chromosomes, can be transferred to another cell to complete the process of genetic modification.
• The chart describes how the process of genetic modification is completed.
• the constituent parts (内部(nèibù)构造) of a cell

第十九页,共40页。
• To begin the genetic engineering process, first of
第十五页,共40页。
试验(shìyàn)intro 和 conclusion
• The chart describes how water is obtained outdoors.
• Thus, water is collected successfully through evaporation from green plants.
Done= hung(挂),dug(挖),cut(剪), laid , turned on(打开(dǎ kāi)),open,filled, removed, put, pasted,covered, uncovered…….. are applied=复杂的做(用)法
第九页,共40页。
• 为了什么目的(mùdì)(in order to+ 主动语态) • and stones are applied on both sides of the sheet

(完整版)Diagram,FlowChart,Map雅思写作流程图讲义

(完整版)Diagram,FlowChart,Map雅思写作流程图讲义
After cooling, the glass products of different shapes are done.
Flow chart Writing
Finally, in stage three, the goods with glass containers appear in the customer supermarkets and this is the end of the cycle and the beginning of the next.
Flow chart Writing
Then the second stage starts when the recycled glass is showered by high pressured water. After that, the glass objects are categorized by color into brown, green and clear ones, before they are conveyed into recycling plant.
Diagram
Diagram Writing
The diagram below shows the method of obtaining water outdoors. You should spend about 20 minutes on this task. You should write at least 150 words.
Flow chart Writing
Structure
Introduction Stage 1 Stage 2 … Conclusion (if needed)
Opening Sentence Struture

精选工艺流程分析

精选工艺流程分析

工艺流程绩效指标
操作时间Operation time = 安装时间(调整或准备时间)Setup time + 运行时间Run time 总生产时间Throughput time = Average time for a unit to move through the system工艺周转率Velocity(Throughput ratio) = 总生产时间Throughput time附加值时间 Value-added time
How Important is It?
Case
McDonald VS Chinese FoodLas Vegas Slot Machine: Mechanical VS Electronic
Байду номын сангаас工艺流程的定义及描述
工艺流程(Process) 是指能够把一定投入变换成一定产出的一系列任务(即工序),这些任务由物流和信息流有机地连接在一起流程图(Flowchart)是分析流程的一个理想的工具
工艺流程中的一些基本概念(1)
工艺( Process )是指能够把一定投入变换成一定产出的一系列任务(即工序),这些任务由物流和信息流有机地连接在一起。周期( Cycle Time )是指连续完成相同的两个产品之间的间隔时间,即完成一个产品所需的平均时间,通常只是用于定义一个流程中某一具体工序或环节的单位产出时间。生产能力(Capacity)是指一个设施的最大产出率,设施可以是一个工序、一台设备,可以是由若干工序或若干设备组成的一个流程,也可以是整个企业组织。一个流程或工序的能力正好是其周期的倒数。生产能力利用率(Utilization)是指相对于生产能力所实际获得的产出。瓶颈(Bottleneck)是指一个流程中周期最长的工序或环节,它限制了流程的能力或最大产出。空闲时间(Idle Time)是指工作时间内没有执行有效工作任务的那段时间,可以指设备或人的时间。流程的平衡(Flow Balance)是指使流程中各个工序都与瓶颈同步,缓解瓶颈,减少空闲时间。

5.章海涛-临床RCT的质量评估临床RCT的质量评估-8-25终稿

5.章海涛-临床RCT的质量评估临床RCT的质量评估-8-25终稿

论文章节/主题 样本量 随机方法:
序列的产生
分配隐藏机制
实施 盲法
条目号 对照检查的条目
6b
试验开始后对结局指标是否有任何更改,并说明原因
7a
如何确定样本量
7b
必要时,解释中期分析和试验中止原则
8a
产生随机分配序列的方法
8b
随机方法的类型,区组和各区组样本多少)
任何限定的细节(如怎样分)
9
用于执行随机分配序列的机制(例如按序编码的封藏
来自高偏倚风险研 究的信息比例足以 影响结果的解释
如何评估临床RCT质量
研究设计 研究人员 项目监查执行情况 统计处理 RCT报告
临床试验数据质量的评估
数据错误的来源与原因
常见来源----源数据采集不正确:因缺乏验证工具或表格设计不合理 原因----如误解、管理不善,疏忽与弄虚作假等
研究质量低可能与研究报告不恰当有关
在已发表文章中,对RCT研究的报告很多不恰当; 99篇RCT,对随机方法正确的93 篇RCT 进行评价,其中
62 篇(66.7%)描述了各组的基线情况和临床特征; 16 篇(17.2%)提及了产生随机分配序列的方法,其中5
篇(5.4%)提及用计算机产生随机分配序列; 9 篇(9.7%)采用盲法的文献中2 篇仅提及“盲法”二字,
法),描述干预措施分配之前为隐藏序列号所采取的
步骤
10
谁产生随机分配序列,谁招募受试者,谁给受试者分
配干预措施
11a 如果实施了盲法,分配干预措施之后对谁设盲(例如 受试者、医护提供者、结局评估者),以及盲法是如
何实施的
11b 如有必要,描述干预措施的相似之处
报告页码

医疗研究报告规范CONSORT声明

医疗研究报告规范CONSORT声明

示例关键点: 主要终点指标、 预期差异、 I类错误α值、 单侧/双侧假设、 power值、 脱落率
18/32
方法(Methods)
➢ 7b: 如有,需解释中间分析和停顿标准 ➢ Many trials recruit participants over a long period. If an intervention
医疗研究报告规范CONSORT声明
3/32
Why
医学研究汇报规范
医疗研究报告规范CONSORT声明
4/ /32
What
CONSORT (Consolidated Standards of Reporting Trials): 针对随机对照临床试验汇报规范。 已被多家期刊广泛采取,包含New Engl J Med (59.558) 、 Lancet (44.002 )、J Am Med Assoc (37.684 )、Lancet Oncol (26.509 )、J Clin Oncol (20.982)、Brit Med J (19.697 )、Plos Med (13.585 )、Medicine (2.133)等。 CONSORT 修订版。 包含: 含有25个条目标列表和1个流程图。
CONSORT Flow Diagram
医疗研究报告规范CONSORT声明
25/32
结果(Results)
➢ 14a 决定病人入选标准和随访时间 ➢ 14b 为何试验结束或停顿
➢ 15 各组人口统计学和临床特征基线资料表格 ➢ 16 每组参加人数(分母)包含每次分析时及是否按最初分配进行
分析均被包含进去, 是否按最初分组分析
Allocated to intervention (n= )

七年级英语数据统计单选题80题

七年级英语数据统计单选题80题

七年级英语数据统计单选题80题1. There are 20 boys and 15 girls in the class. What's the total number of students?A. 20B. 15C. 35D. 5答案:C。

这道题考查简单的加法运算。

班级里有20 个男孩和15 个女孩,总人数就是20 + 15 = 35 人。

选项A 只是男孩的数量;选项B 只是女孩的数量;选项D 与实际计算结果不符。

2. In a survey, 18 people like apples and 12 people like bananas. How many more people like apples than bananas?A. 6B. 30C. 8D. 2答案:A。

这道题考查减法运算。

喜欢苹果的有18 人,喜欢香蕉的有12 人,喜欢苹果比喜欢香蕉多的人数是18 - 12 = 6 人。

选项B 是两者之和;选项C 和D 计算错误。

3. The temperature in the morning was 15°C and it rose by 5°C in the afternoon. What was the temperature in the afternoon?A. 10°CB. 20°CC. 5°CD. 25°C答案:B。

这道题考查加法运算。

早上温度是15°C,下午升高了5°C,下午的温度就是15 + 5 = 20°C。

选项A 是温度降低后的结果;选项C 是升高的度数;选项D 计算错误。

4. A store sold 30 shirts on Monday and 25 shirts on Tuesday. How many shirts did the store sell in total in these two days?A. 55B. 5C. 65D. 15答案:A。

RCT临床研究遵循CONSORT规范(汉语版)

RCT临床研究遵循CONSORT规范(汉语版)
Participants 受试者
4a
Eligibility criteria for participants 受试者的纳入、排除和退出标准
4b
Settings and locations where the data were collected 数据收集的环境及地点
4c
伦理学至上原则
Interventions 干预方法
序列产生;分配遮蔽;实施
8b
Type of randomisation; details of any restriction (such as blocking and block size)
随机化形式,以及描述随机细节(如是否有区组化,有的话,区组是多少?)
Allocation concealment mechanism 遮蔽实施的细节
7b
When applicable, explanation of any interim analyses and stopping guidelines
必要时,解释期中分析及试验终止原则
Randomisation: 随机化
Sequence generation 随机序列产生的方法
8a
Method used to generate the random allocation sequence
Outcomes 结局指标
6a
Completely defined pre-specified primary and secondary outcome measures, including how and when they were assessed
明确定义预先指定的首要和次要结局变量,包括了解如何和何时进行评价

211245384_基于直观汉字构形原理的C3-GAN字体生成优化方法

211245384_基于直观汉字构形原理的C3-GAN字体生成优化方法

第44卷 第10期 包 装 工 程2023年5月 PACKAGING ENGINEERING 193收稿日期:2022–12–02基金项目:2023年河北省教育厅人文社会科学研究重大课题攻关项目(ZD202327)阶段性成果。

作者简介:秦嘉霖(1994—),女,硕士,主要研究方向为字体设计。

基于直观汉字构形原理的C 3-GAN 字体生成优化方法秦嘉霖1,2,刘维尚1(1.燕山大学,河北 秦皇岛 066004;2.河北省设计创新及产业发展研究中心,河北 秦皇岛 066004) 摘要:目的 为了提升生成对抗网络汉字风格迁移的图像生成质量,实现汉字智能生成在字库产业中的实际应用,提出了一种基于直观汉字构形学的条件生成对抗网络字体生成优化方法(Optimization of Conditional Fonts Generation with Chinese Character Configuration GANs ,C 3-GAN )。

方法 建构了直观汉字构形模组(C 3Module ),该模组包含了利于条件生成对抗网络进行汉字构形语义特征学习的全特征汉字字符集。

C 3-GAN 在条件生成对抗网络模型下进行字体生成训练,降低了必要训练样本数量,实现对字体生成效果的优化。

结果 使用C 3-GAN 生成汉字图像的清晰度更高、字形更准确。

在图像相似性定量评估中,使用C 3-GAN 的实验组相比于其他模型,获得了更高的相似值和更小的误差值。

结论 使用C 3-GAN 可以降低必要训练样本数量、提升汉字图像质量。

在实际项目中具有一定的应用性和可操作性。

关键词:生成对抗网络;汉字构形;人工智能;深度学习;汉字字体;C 3-GAN 中图分类号:TB472 文献标识码:A 文章编号:1001-3563(2023)10-0193-09 DOI :10.19554/ki.1001-3563.2023.10.019C 3-GAN Fonts Generation Optimization Based on IntuitiveChinese Character ConfigurationQIN Jia-lin 1,2, LIU Wei-shang 1(1.Yanshan University, Hebei Qinhuangdao 066004, China;2.Hebei Design Innovation and Industrial Development Research Center, Hebei Qinhuangdao 066004, China) ABSTRACT: The work aims to propose a method for Optimization of Conditional Fonts Generation with Chinese Character Configuration GANs (C 3-GAN) of the intuitive Chinese character configuration to improve the image generation quality of Chinese character style transferring with generative adversarial networks, and achieve the practical application of Chinese character intelligent generation in the font industry. An intuitive Chinese character configuration module (C 3 Module) was constructed, which contained Chinese character sets with all features. It was beneficial to generating an adversarial network for the learning process of semantic features of Chinese character configuration. Performing font generation training with C 3-GAN under the model of the conditional generative adversarial network reduced the number of compulsory training samples, and optimized the font generation effect. C 3-GAN could generate Chinese characters with higher images definition and more accurate glyphs. In the quantitative evaluation of image similarity, the experimental group using C 3-GAN obtained higher similarity values and smaller error values than other models. C 3-GAN can reduce the number of compulsory samples, and improve the image quality of Chinese characters. It has certain applicability and operability in practical projects.KEY WORDS: generative adversarial networks; Chinese character configuration; artificial intelligence; deep learning; Chinese character font; C 3-GAN194 包装工程 2023年5月近年来人工智能技术以其强大的数据分析能力和运算能力被广泛应用。

Diagram--Flow-Chart--Map-雅思写作流程图讲义

Diagram--Flow-Chart--Map-雅思写作流程图讲义

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The flow chart illustrates how used glass is recycled and the whole cycled process can be divided into three major stages.
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The glass, then, is poured into a furnace where it melts into liquid. Later, the recycled liquid glass, together with new liquid glass from other sources, is channeled into various moulds.

质量改进过程的10个通用步骤及其应用工具矩阵

质量改进过程的10个通用步骤及其应用工具矩阵

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Diagram, Flow Chart, Map 雅思写作流程图讲义

Diagram, Flow Chart, Map 雅思写作流程图讲义

bthe furnace
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Flow chart Writing
The flow chart illustrates how used glass is recycled and the whole cycled process can be divided into three major stages.
deliver, send 分类: sort, classify, categorize…+into) d, sequence 顺序清晰: first, next, finally… e, 1st sentence = last sentence (表循环)
E.g. The water falls as rain. It…from clouds. The clouds wool and they drop water as rain.
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used glass / glass waste / glass bottle / glass can
reclaim / gather / collect
transport / convey / deliver
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sort / group / categorize / channel into
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Then the second stage starts when the recycled glass is showered by high pressured water. After that, the glass objects are categorized by color into brown, green and clear ones, before they are conveyed into recycling plant.

(完整word版)RCT临床研究遵循CONSORT规范(中文版)

(完整word版)RCT临床研究遵循CONSORT规范(中文版)
RCT临床研究遵循CONSORT规范(中文版)
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题目中说明研究的性质,如随机对照双盲研究
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结构式摘要,按期刊要求
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Sequence generation随机序列产生的方法
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