Elementary counterexamples to Kodaira vanishing in prime characteristic
Counterexamples to a conjecture of Lemmermeyer
Lemma 2 Let G = G(m, n) := a, b|am, bn, [b, a] = a4 , where m and n are powers of 2, m ≥ 16, n ≥ 4, m ≤ 4n. Then G has order mn, G′ = a4 is cyclic of
It is interesting to note that 4 of the 18 known counterexamples of order 128 (namely numbers 45, 100, 841, 886) have quotients isomorphic to our counterexamples of order 64, but that in each case the kernel is not characteristic.
1991 Mathematics Subject Classification. 11R37, 20D15. The first author was partially supported by NSF grant DMS 96-22590.
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NIGEL BOSTON AND CHARLES LEEDHAM-GREEN
1. Introduction.
Let K be a quadratic number field, H be its Hilbert class field, and H2 its Hilbert 2-class field (in other words, the maximal everywhere unramified abelian and 2-abelian extensions of K respectively). There has been much work recently regarding the possible structure of Gal(H/K) and Gal(H2/K) (which are isomorphic to the ideal class group of K and its 2-Sylow subgroup respectively). For instance, the conjectures of Cohen and Lenstra [2] suggest that every abelian group (respectively abelian 2-group) should appear as Gal(H/K) (respectively Gal(H2/K)) for a suitable choice of K.
latex英文模板
\documentclass{article}\usepackage{graphicx}\usepackage[round]{natbib}\bibliographystyle{plainnat}\usepackage[pdfstartview=FitH,%bookmarksnumbered=true,bookmarksopen=true,%colorlinks=true,pdfborder=001,citecolor=blue,%linkcolor=blue,urlcolor=blue]{hyperref}\begin{document}\title{Research plan under the Post-doctorate program at xx University}%\subtitle{aa}\author{Robert He}\date{2008/04/23}\maketitle\section{Research Title}~~~~Crustal seismic anisotropy in the xx using Moho P-to-S converted phases.\section{Research Background \& Purposes}~~~~Shear-wave splitting analyses provide us a new way to study the seismic structure and mantle dynamics in the crust and mantle. The crustal anisotropy is developed due to various reasons including lattice-preferred orientation (LPO) of mineral crystals and oriented cracks.\newlineTraditionally, the earthquakes occurring in the curst and the subducting plates are selected to determine the seismic anisotropy of the crust. However, none of these methods can help us to assess the anisotropy in the whole crust. Because crustal earthquakes mostly are located in the upper crust, they do not provide information of lower crust. On the other hand, earthquakes in the subducting plates provide information of the whole crust but combined with upper mantle. However, it’s difficult to extract the sole contri bution of the crust from the measurement. Fortunately P-to-S converted waves (Ps) at the Moho are ideal for investigation of crustal seismic anisotropy since they are influenced only by the medium above the Moho.Moho. Figure \ref{crustalspliting}~schematically shows the effects of shear wave splitting on Moho Ps phases. Initially, a near-vertically incident P wave generates a radially polarized converted shear wave at the crust-mantle boundary. The phases, polarized into fast and slow directions, progressively split in time as they propagate through the anisotropic media. Here, the Ps waves can be obtained from teleseismic receiver function analysis.%%\begin{figure}[htbp]\begin{center}\includegraphics[width=0.47\textwidth]{crustalsplit.png}\caption{The effects of shear wave splitting in the Moho P to S converted phase. Top shows a schematic seismogram in the fast/slow coordinate system with split horizontal Ps components.(cited from: McNamara and Owens, 1993)}\label{crustalspliting}\end{center}\end{figure}%%The Korean Peninsula is composed of three major Precambrian massifs, the Nangrim, Gyeongii, and Yeongnam massifs(Fig.\ref{geomap}). The Pyeongbuk-Gaema Massif forms the southern part of Liao-Gaema Massif of southern Manchuria, and the Gyeonggi and Mt. Sobaeksan massifs of the peninsula are correlated with the Shandong and Fujian Massifs of China.%\begin{figure}[htbp]\begin{center}\includegraphics[width=0.755\textwidth]{geo.png}\caption{Simplified geologic map. NCB: North China block; SCB: South China block.(cited from: Choi et al., 2006)}\label{geomap}\end{center}\end{figure}%Our purpose of the study is to measure the shear wave splitting parameters in the crust of the Korean Peninsula. The shear wave splitting parameters include the splitting time of shear energybetween the fast and slow directions, as well as fast-axis azimuthal direction in the Korean Peninsula. These two parameters provide us constraints on the mechanism causing the crustal anisotropy. From the splitting time, the layer thickness of anisotropy will be estimated. Whether crustal anisotropy mainly contributed by upper or lower crustal or both will be determined. Based on the fast-axis azimuthal direction, the tectonic relation between northeastern China and the Korean peninsula will be discussed.\section{Research Methods}~~~~Several methods have been introduced for calculation of receiver functions. An iterative deconvolution technique may be useful for this study since it produces more stable receiver function results than others. The foundation of the iterative deconvolution approach is aleast-squares minimization of the difference between the observed horizontal seismogram and a predicted signal generated by the convolution of an iteratively updated spike train with the vertical-component seismogram. First, the vertical component is cross-correlated with the radial component to estimate the lag of the first and largest spike in the receiver function (the optimal time is that of the largest peak in the absolute sense in the cross-correlation signal). Then the convolution of the current estimate of the receiver function with the vertical-component seismogram is subtracted from the radial-component seismogram, and the procedure is repeated to estimate other spike lags and amplitudes. With each additional spike in the receiver function, the misfit between the vertical and receiver-function convolution and the radial component seismogram is reduced, and the iteration halts when the reduction in misfit with additional spikes becomes insignificant.\newlineFor all measurement methods of shear-wave splitting, time window of waveform should be selected. Conventionally the shear-wave analysis window is picked manually. However, manual window selection is laborious and also very subjective; in many cases different windows give very different results.\newlineIn our study, the automated S-wave splitting technique will be used, which improves the quality of shear-wave splitting measurement and removes the subjectivity in window selection. First, the splitting analysis is performed for a range of window lengths. Then a cluster analysis isapplied in order to find the window range in which the measurements are stable. Once clusters of stable results are found, the measurement with the lowest error in the cluster with the lowest variance is presented for the analysis result.\section{Expected results \& their contributions}~~~~First, the teleseismic receiver functions(RFs) of all stations including radial and transverse RFs can be gained. Based on the analysis of RFs, the crustal thickness can be estimated in the Korean Peninsula. Then most of the expected results are the shear-wave splitting parameters from RFs analysis in the crust beneath the Korean Peninsula. The thickness of anisotropic layer will be estimated in the region when the observed anisotropy is assumed from a layer of lower crustal material.All the results will help us to understand the crustal anisotropy source.\newlineCrustal anisotropy can be interpreted as an indicator of the crustal stress/strain regime. In addition, since SKS splitting can offer the anisotropy information contributed by the upper mantle but combined with the crust, the sole anisotropy of the upper mantle can be attracted from the measurement of SKS splitting based on the crustal splitting result.%\cite{frogge2007}%%%\citep{frogge2008}%%%\citep{s-frogge2007}% 5. References\begin{thebibliography}{99}\item Burdick, L. J. and C. A. Langston, 1977, Modeling crustal structure through the use of converted phases in teleseismic body waveforms, \textit{Bull. Seismol. Soc. Am.}, 67:677-691.\item Cho, H-M. et al., 2006, Crustal velocity structure across the southern Korean Peninsula from seismic refraction survey, \textit{Geophy. Res. Lett.} 33, doi:10.1029/2005GL025145.\item Cho, K. H. et al., 2007, Imaging the upper crust of the Korean peninsula by surface-wave tomography, \textit{Bull. Seismol. Soc. Am.}, 97:198-207.\item Choi, S. et al., 2006, Tectonic relation between northeastern China and the Korean peninsula revealed by interpretation of GRACE satellite gravity data, \textit{Gondwana Research}, 9:62-67.\item Chough, S. K. et al., 2000, Tectonic and sedimentary evolution of the Korean peninsula: a review and new view, \textit{Earth-Science Reviews}, 52:175-235.\item Crampin, S., 1981, A review of wave motion in anisotropic and cracked elastic-medium, \textit{Wave Motion}, 3:343-391.\item Fouch, M. J. and S. Rondenay, 2006, Seismic anisotropy beneath stable continental interiors, \textit{Phys. Earth Planet. Int.}, 158:292-320.\item Herquel, G. et al., 1995, Anisotropy and crustal thickness of Northern-Tibet. New constraints for tectonic modeling, \textit{Geophys. Res. Lett.}, 22(14):1 925-1 928.\item Iidaka, T. and F. Niu, 2001, Mantle and crust anisotropy in the eastern China region inferred from waveform splitting of SKS and PpSms, \textit{Earth Planets Space}, 53:159-168.\item Kaneshima, S., 1990, Original of crustal anisotropy: Shear wave splitting studies in Japan, \textit{J. Geophys. Res.}, 95:11 121-11 133.\item Kim, K. et al., 2007, Crustal structure of the Southern Korean Peninsula from seismic wave generated by large explosions in 2002 and 2004, \textit{Pure appl. Geophys.}, 164:97-113.\item Kosarev, G. L. et al., 1984, Anisotropy of the mantle inferred from observations of P to S converted waves, \textit{Geophys. J. Roy. Astron. Soc.}, 76:209-220.\item Levin, V. and J. Park, 1997, Crustal anisotropy in the Ural Mountains foredeep from teleseismic receiver functions, \textit{Geophys. Res. Lett.}, 24(11):1 283 1286.\item Ligorria, J. P. and C. J. Ammon, 1995, Iterative deconvolution and receiver-function estimation. \textit{Bull. Seismol. Soc. Am.}, 89:1 395-1 400.\item Mcnamara, D. E. and T. J. Owens, 1993, Azimuthal shear wave velocity anisotropy in the basin and range province using Moho Ps converted phases, \textit{J. Geophys. Res.}, 98:12003-12 017.\item Peng, X. and E. D. Humphreys, 1997, Moho dip and crustal anisotropy in northwestern Nevada from teleseismic receiver functions, \textit{Bull. Seismol. Soc. Am.}, 87(3):745-754.\item Sadidkhouy, A. et al., 2006, Crustal seismic anisotropy in the south-central Alborz region using Moho Ps converted phases, \textit{J. Earth \& Space Physics}, 32(3):23-32.\item Silver, P. G. and W. W. Chan, 1991, Shear wave splitting and subcontinental mantle deformation, \textit{J. Geophys. Res.},96:16 429-16454.\item Teanby, N. A. et al., 2004, Automation of shear wave splitting measurement using cluster analysis, \textit{Bull. Seismol. Soc. Am.}, 94:453-463.\item Vinnik, L. and J-P. Montagner, 1996, Shear wave splitting in the mantle Ps phases,\textit{Geophys. Res. Lett.}, 23(18):2 449- 2 452.\item Yoo, H. J. et al., 2007, Imaging the three-dimensional crust of the Korean peninsula by joint inversion of surface-wave dispersion of teleseismic receiver functions, \textit{Bull. Seismol. Soc. Am.}, 97(3):1 002-1 011.\item Zhu, L., and H. Kanamori, 2000, Moho depth variation in Southern California from teleseismic receiver functions, \textit{J. Geophys. Res.}, doi :10.1029/1999JB900322, 105:2 969-2 980.%%%%\end{document}。
KODAK EKTACHROME 反转色彩胶片处理方法 - 方法 E-6 Z-119 第六版说明书
1OVERVIEW OF PROCESSINGKODAK EKTACHROME FILMSKODAK EKTACHROME films are reversal, subtractive color materials. When properly exposed and processed, they yield positive color images, i.e., transparencies.The general structure of EKTACHROME Films is shown in Figure 1-1, enlarged to show detail. The transparent film support is at the bottom of the illustration. Reversal films contain three emulsion layers that are light-sensitive. The red-sensitive emulsion layer is located at the bottom of the film closest to the support material. The green-sensitive layer is located in the middle, and the blue-sensitive layer is at the top. Although the red-sensitive layer is primarily sensitive to red light and the green-sensitive layer is primarily sensitive to green light, both of these layers are somewhat sensitive to blue light. The yellow filter layer absorbs blue light and prevents blue light from exposing the red- and green-sensitive layers.When reversal film is exposed, latent images are formed in each of the three emulsion layers. The blue-sensitive layer contains a record of the images formed by the blue component of the exposing light; the green-sensitive layer contains the image formed by the green component; and the red-sensitive layer contains the image formed by the red component. The images are formed simultaneously and are superimposed.Figure 1-2 shows the formation of the color image during processing. For more information about each processing step in Process E-6, see the descriptions on page 1-2.Figure 1-1PROCESS E-6Understanding Solution FunctionsUse the following descriptions to become familiar with the function of each processing solution. This understanding, along with the information in section 14, “Diagnostic Charts,” and section 15, “Control-Chart Examples,” will help you analyze process problems.First DeveloperThe chemical reducing action of the first developer converts exposed silver halide grains (the latent image) into metallic silver (the silver image). This is a negative image. The first developer step is the most critical step of Process E-6. The amount of silver formed depends on developer activity. Time, temperature, agitation, developer concentration, and utilization affect first-developer activity. In Process E-6, increased first-developer activity causes too little dye to form; decreased activity causes more dye than normal to form.First WashThe first wash stops the action of the first developer and removes first developer solution from the film. Insufficient water flow, incorrect temperature, or too little wash time will affect density (speed) and color balance.Reversal BathThe reversal bath prepares the film for the color-developer step. A chemical reversal agent is absorbed into the emulsion and prepares the remaining silver halide for the chemical reversal that occurs in the color developer. Do not use a wash between the reversal bath and the color developer; the reversal agent must be in the emulsion when the film enters the color developer.Incorrect replenishment, excessive oxidation, incorrect mixing, and utilization can affect overall density and color balance.Color DeveloperWhen film enters the color developer, the reversal agent absorbed by the emulsion in the reversal bath chemically “exposes” the remaining silver halide. The color developing agent then reacts with the silver halide to form metallic silver. As this metallic silver image is formed, the oxidized color developer agent reacts with the color couplers in each of the three dye layers (yellow, magenta, and cyan) of the film to form colored dyes. The dye forms only at the sites where the image was converted to metallic silver. Changes in the color developer pH, agitation, time, temperature, developer concentration, utilization, and replenishment rate affect color balance, contrast, maximum density, minimum density, and uniformity.Pre-BleachThe pre-bleach prepares the metallic silver developed in the first and color developers for oxidation to silver halide in the bleach step. It helps preserve the acidity of the bleach solution by reducing carryover of color developer into the bleach. The pre-bleach also enhances dye stability. Pre-bleach that is too concentrated can cause leuco-cyan dye to form, resulting in low red D-max. If the pre-bleach is too dilute, the dye stability could be substandard. Do not use a wash between the pre-bleach and the bleach; pre-bleach carry-in is necessary for proper bleaching.BleachThe bleach converts the metallic silver image back to silver halide; the silver halide is later removed in the fixer. During bleaching, iron III is reduced to iron II. Iron II must be converted back to iron III by aeration so that satisfactory bleaching can continue. Aerate the bleach by bubbling air through it.Inadequate aeration, underreplenishment, too little time, low temperature, and over-dilution by pre-bleach can cause silver retention, low red D-max, high blue D-max (and to a lesser degree, high green D-max), and yellow D-min. FixerThe fixer converts all of the silver halide into soluble silver compounds. Most of the silver compounds are removed in the fixer and can be recovered.You must aerate any bleach carried into the fixer (by bubbling air into the fixer or with manual agitation) to prevent exhausted bleaching agent from causing leuco-cyan dye to form. However, too much air will oxidize the fixer; aerate the fixer only when film is in the fixer.Too little time, underreplenishment, or fixer dilution will cause silver-halide retention, increased blue density, or yellow D-min.Final WashThe final wash removes chemicals remaining in the film emulsion. Complete washing at this stage is important for image stability; any chemicals remaining in the film may deteriorate the image dyes. For best results, use a 2-stage countercurrent-flow wash.Final RinseThe final rinse contains a wetting agent to reduce water spotting and provide uniform drying. To help prevent water spots and streaks, maintain solution cleanliness by replacing the final rinse once a week or more frequently.。
计数电眼 英语
计数电眼英语The Digital Eye: A New Era of SurveillanceIn the ever-evolving landscape of technology, the digital eye has emerged as a powerful tool, transforming the way we perceive and interact with the world around us. Once a mere concept in the realm of science fiction, this innovative technology has infiltrated various aspects of our lives, redefining the boundaries of privacy and security.The digital eye, often referred to as surveillance technology, has become an integral part of our modern infrastructure. From public spaces to private domains, these sophisticated cameras and sensors are ubiquitous, capturing every movement and recording every interaction. The implications of this technological advancement are far-reaching, sparking debates and raising ethical concerns as we grapple with the delicate balance between public safety and individual liberty.One of the primary applications of the digital eye lies in the realm of security and crime prevention. Law enforcement agencies have embraced this technology, utilizing it to monitor high-traffic areas, identify potential threats, and respond to emergencies with greaterefficiency. The ability to track and analyze patterns of behavior has proven invaluable in disrupting criminal activities and ensuring the safety of communities. However, the use of surveillance cameras has also raised concerns about privacy infringement, as citizens may feel their movements are constantly under scrutiny.Beyond the realm of public safety, the digital eye has found its way into our private lives. Smart home devices equipped with cameras and sensors have become increasingly commonplace, allowing us to monitor our living spaces remotely and maintain a sense of control over our domestic environments. From security cameras that watch over our homes to intelligent personal assistants that respond to our every command, the digital eye has infiltrated the most intimate corners of our lives, blurring the line between convenience and invasion of privacy.The impact of the digital eye extends far beyond the realm of security and surveillance. In the business sector, this technology has revolutionized the way companies operate, enabling them to gather valuable data and optimize their strategies. Retailers, for instance, utilize facial recognition software to track customer behavior, analyze shopping patterns, and personalize their marketing efforts. While this data-driven approach can lead to more tailored experiences for consumers, it also raises concerns about the protection of personal information and the potential for abuse.The educational sector has also embraced the digital eye, incorporating it into the classroom to enhance the learning experience. Cameras and sensors are used to monitor student engagement, track attendance, and even detect potential cheating behaviors. Proponents of this technology argue that it can help identify areas for improvement and optimize teaching methods, but critics warn of the risks associated with the constant surveillance of students and the potential for misuse.The influence of the digital eye is not limited to the physical world; it has also permeated the digital realm. Social media platforms, often equipped with facial recognition and location-tracking capabilities, have become a goldmine of personal data, allowing companies and governments to gather unprecedented insights into our social interactions, interests, and movements. This data can be leveraged for targeted advertising, political influence, and even social control, raising serious concerns about the privacy and autonomy of individuals in the digital age.As the digital eye continues to evolve and expand its reach, the need to address the ethical and legal implications of this technology has become increasingly urgent. Policymakers and regulatory bodies must work diligently to strike a balance between the benefits of surveillance and the protection of individual rights, ensuring that thedigital eye is deployed in a manner that respects privacy, promotes transparency, and safeguards against abuse.The future of the digital eye is not without its challenges, but it is also rife with potential. As we navigate this new era of ubiquitous surveillance, it is incumbent upon us to engage in open and informed discussions, to question the boundaries of this technology, and to shape its development in a way that preserves the core values of a free and democratic society. Only by doing so can we harness the power of the digital eye while safeguarding the fundamental rights and freedoms that define our humanity.。
Peters (2010) Episodic Future Thinking Reduces Reward Delay Discounting
NeuronArticleEpisodic Future Thinking ReducesReward Delay Discounting through an Enhancement of Prefrontal-Mediotemporal InteractionsJan Peters1,*and Christian Bu¨chel11NeuroimageNord,Department of Systems Neuroscience,University Medical Center Hamburg-Eppendorf,Hamburg20246,Germany*Correspondence:j.peters@uke.uni-hamburg.deDOI10.1016/j.neuron.2010.03.026SUMMARYHumans discount the value of future rewards over time.Here we show using functional magnetic reso-nance imaging(fMRI)and neural coupling analyses that episodic future thinking reduces the rate of delay discounting through a modulation of neural decision-making and episodic future thinking networks.In addition to a standard control condition,real subject-specific episodic event cues were presented during a delay discounting task.Spontaneous episodic imagery during cue processing predicted how much subjects changed their preferences toward more future-minded choice behavior.Neural valuation signals in the anterior cingulate cortex and functional coupling of this region with hippo-campus and amygdala predicted the degree to which future thinking modulated individual preference functions.A second experiment replicated the behavioral effects and ruled out alternative explana-tions such as date-based processing and temporal focus.The present data reveal a mechanism through which neural decision-making and prospection networks can interact to generate future-minded choice behavior.INTRODUCTIONThe consequences of choices are often delayed in time,and in many cases it pays off to wait.While agents normally prefer larger over smaller rewards,this situation changes when rewards are associated with costs,such as delays,uncertainties,or effort requirements.Agents integrate such costs into a value function in an individual manner.In the hyperbolic model of delay dis-counting(also referred to as intertemporal choice),for example, a subject-specific discount parameter accurately describes how individuals discount delayed rewards in value(Green and Myer-son,2004;Mazur,1987).Although the degree of delay discount-ing varies considerably between individuals,humans in general have a particularly pronounced ability to delay gratification, and many of our choices only pay off after months or even years. It has been speculated that the capacity for episodic future thought(also referred to as mental time travel or prospective thinking)(Bar,2009;Schacter et al.,2007;Szpunar et al.,2007) may underlie the human ability to make choices with high long-term benefits(Boyer,2008),yielding higher evolutionaryfitness of our species.At the neural level,a number of models have been proposed for intertemporal decision-making in humans.In the so-called b-d model(McClure et al.,2004,2007),a limbic system(b)is thought to place special weight on immediate rewards,whereas a more cognitive,prefrontal-cortex-based system(d)is more involved in patient choices.In an alternative model,the values of both immediate and delayed rewards are thought to be repre-sented in a unitary system encompassing medial prefrontal cortex(mPFC),posterior cingulate cortex(PCC),and ventral striatum(VS)(Kable and Glimcher,2007;Kable and Glimcher, 2010;Peters and Bu¨chel,2009).Finally,in the self-control model, values are assumed to be represented in structures such as the ventromedial prefrontal cortex(vmPFC)but are subject to top-down modulation by prefrontal control regions such as the lateral PFC(Figner et al.,2010;Hare et al.,2009).Both the b-d model and the self-control model predict that reduced impulsivity in in-tertemporal choice,induced for example by episodic future thought,would involve prefrontal cortex regions implicated in cognitive control,such as the lateral PFC or the anterior cingulate cortex(ACC).Lesion studies,on the other hand,also implicated medial temporal lobe regions in decision-making and delay discounting. In rodents,damage to the basolateral amygdala(BLA)increases delay discounting(Winstanley et al.,2004),effort discounting (Floresco and Ghods-Sharifi,2007;Ghods-Sharifiet al.,2009), and probability discounting(Ghods-Sharifiet al.,2009).Interac-tions between the ACC and the BLA in particular have been proposed to regulate behavior in order to allow organisms to overcome a variety of different decision costs,including delays (Floresco and Ghods-Sharifi,2007).In line with thesefindings, impairments in decision-making are also observed in humans with damage to the ACC or amygdala(Bechara et al.,1994, 1999;Manes et al.,2002;Naccache et al.,2005).Along similar lines,hippocampal damage affects decision-making.Disadvantageous choice behavior has recently been documented in patients suffering from amnesia due to hippo-campal lesions(Gupta et al.,2009),and rats with hippocampal damage show increased delay discounting(Cheung and Cardinal,2005;Mariano et al.,2009;Rawlins et al.,1985).These observations are of particular interest given that hippocampal138Neuron66,138–148,April15,2010ª2010Elsevier Inc.damage impairs the ability to imagine novel experiences (Hassa-bis et al.,2007).Based on this and a range of other studies,it has recently been proposed that hippocampus and parahippocam-pal cortex play a crucial role in the formation of vivid event repre-sentations,regardless of whether they lie in the past,present,or future (Schacter and Addis,2009).The hippocampus may thus contribute to decision-making through its role in self-projection into the future (Bar,2009;Schacter et al.,2007),allowing an organism to evaluate future payoffs through mental simulation (Johnson and Redish,2007;Johnson et al.,2007).Future thinking may thus affect intertemporal choice through hippo-campal involvement.Here we used model-based fMRI,analyses of functional coupling,and extensive behavioral procedures to investigate how episodic future thinking affects delay discounting.In Exper-iment 1,subjects performed a classical delay discounting task(Kable and Glimcher,2007;Peters and Bu¨chel,2009)that involved a series of choices between smaller immediate and larger delayed rewards,while brain activity was measured using fMRI.Critically,we introduced a novel episodic condition that involved the presentation of episodic cue words (tags )obtained during an extensive prescan interview,referring to real,subject-specific future events planned for the respective day of reward delivery.This design allowed us to assess individual discount rates separately for the two experimental conditions,allowing us to investigate neural mechanisms mediating changes in delay discounting associated with episodic thinking.In a second behavioral study,we replicated the behavioral effects of Exper-iment 1and addressed a number of alternative explanations for the observed effects of episodic tags on discount rates.RESULTSExperiment 1:Prescan InterviewOn day 1,healthy young volunteers (n =30,mean age =25,15male)completed a computer-based delay discounting proce-dure to estimate their individual discount rate (Peters and Bu ¨-chel,2009).This discount rate was used solely for the purpose of constructing subject-specific trials for the fMRI session (see Experimental Procedures ).Furthermore,participants compiled a list of events that they had planned in the next 7months (e.g.,vacations,weddings,parties,courses,and so forth)andrated them on scales from 1to 6with respect to personal rele-vance,arousal,and valence.For each participant,seven subject-specific events were selected such that the spacing between events increased with increasing delay to the episode,and that events were roughly matched based on personal rele-vance,arousal,and valence.Multiple regression analysis of these ratings across the different delays showed no linear effects (relevance:p =0.867,arousal:p =0.120,valence:p =0.977,see Figure S1available online).For each subject,a separate set of seven delays was computed that was later used as delays in the control condition.Median and range for the delays used in each condition are listed in Table S1(available online).For each event,a label was selected that would serve as a verbal tag for the fMRI session.Experiment 1:fMRI Behavioral ResultsOn day 2,volunteers performed two sessions of a delay dis-counting procedure while fMRI was measured using a 3T Siemens Scanner with a 32-channel head-coil.In each session,subjects made a total of 118choices between 20V available immediately and larger but delayed amounts.Subjects were told that one of their choices would be randomly selected and paid out following scanning,with the respective delay.Critically,in half the trials,an additional subject-specific episodic tag (see above,e.g.,‘‘vacation paris’’or ‘‘birthday john’’)was displayed based on the prescan interview (see Figure 1)indicating which event they had planned on the particular day (episodic condi-tion),whereas in the remaining trials,no episodic tag was pre-sented (control condition).Amount and waiting time were thus displayed in both conditions,but only the episodic condition involved the presentation of an additional subject-specific event tag.Importantly,nonoverlapping sets of delays were used in the two conditions.Following scanning,subjects rated for each episodic tag how often it evoked episodic associations during scanning (frequency of associations:1,never;to 6,always)and how vivid these associations were (vividness of associa-tions:1,not vivid at all;to 6,highly vivid;see Figure S1).Addition-ally,written reports were obtained (see Supplemental Informa-tion ).Multiple regression revealed no significant linear effects of delay on postscan ratings (frequency:p =0.224,vividness:p =0.770).We averaged the postscan ratings acrosseventsFigure 1.Behavioral TaskDuring fMRI,subjects made repeated choices between a fixed immediate reward of 20V and larger but delayed amounts.In the control condi-tion,amounts were paired with a waiting time only,whereas in the episodic condition,amounts were paired with a waiting time and a subject-specific verbal episodic tag indicating to the subjects which event they had planned at the respective day of reward delivery.Events were real and collected in a separate testing session prior to the day of scanning.NeuronEpisodic Modulation of Delay DiscountingNeuron 66,138–148,April 15,2010ª2010Elsevier Inc.139and the frequency/vividness dimensions,yielding an‘‘imagery score’’for each subject.Individual participants’choice data from the fMRI session were then analyzed byfitting hyperbolic discount functions to subject-specific indifference points to obtain discount rates (k-parameters),separately for the episodic and control condi-tions(see Experimental Procedures).Subjective preferences were well-characterized by hyperbolic functions(median R2 episodic condition=0.81,control condition=0.85).Discount functions of four exemplary subjects are shown in Figure2A. For both conditions,considerable variability in the discount rate was observed(median[range]of discount rates:control condition=0.014[0.003–0.19],episodic condition=0.013 [0.002–0.18]).To account for the skewed distribution of discount rates,all further analyses were conducted on the log-trans-formed k-parameters.Across subjects,log-transformed discount rates were significantly lower in the episodic condition compared with the control condition(t(29)=2.27,p=0.016),indi-cating that participants’choice behavior was less impulsive in the episodic condition.The difference in log-discount rates between conditions is henceforth referred to as the episodic tag effect.Fitting hyperbolic functions to the median indifference points across subjects also showed reduced discounting in the episodic condition(discount rate control condition=0.0099, episodic condition=0.0077).The size of the tag effect was not related to the discount rate in the control condition(p=0.56). We next hypothesized that the tag effect would be positively correlated with postscan ratings of episodic thought(imagery scores,see above).Robust regression revealed an increase in the size of the tag effect with increasing imagery scores (t=2.08,p=0.023,see Figure2B),suggesting that the effect of the tags on preferences was stronger the more vividly subjects imagined the episodes.Examples of written postscan reports are provided in the Supplemental Results for participants from the entire range of imagination ratings.We also correlated the tag effect with standard neuropsychological measures,the Sensation Seeking Scale(SSS)V(Beauducel et al.,2003;Zuck-erman,1996)and the Behavioral Inhibition Scale/Behavioral Approach Scale(BIS/BAS)(Carver and White,1994).The tag effect was positively correlated with the experience-seeking subscale of the SSS(p=0.026)and inversely correlated with the reward-responsiveness subscale of the BIS/BAS scales (p<0.005).Repeated-measures ANOVA of reaction times(RTs)as a func-tion of option value(lower,similar,or higher relative to the refer-ence option;see Experimental Procedures and Figure2C)did not show a main effect of condition(p=0.712)or a condition 3value interaction(p=0.220),but revealed a main effect of value(F(1.8,53.9)=16.740,p<0.001).Post hoc comparisons revealed faster RTs for higher-valued options relative to similarly (p=0.002)or lower valued options(p<0.001)but no difference between lower and similarly valued options(p=0.081).FMRI DataFMRI data were modeled using the general linear model(GLM) as implemented in SPM5.Subjective value of each decision option was calculated by multiplying the objective amount of each delayed reward with the discount fraction estimated behaviorally based on the choices during scanning,and included as a parametric regressor in the GLM.Note that discount rates were estimated separately for the control and episodic conditions(see above and Figure2),and we thus used condition-specific k-parameters for calculation of the subjective value regressor.Additional parametric regressors for inverse delay-to-reward and absolute reward magnitude, orthogonalized with respect to subjective value,were included in theGLM.Figure2.Behavioral Data from Experiment1Shown are experimentally derived discount func-tions from the fMRI session for four exemplaryparticipants(A),correlation with imagery scores(B),and reaction times(RTs)(C).(A)Hyperbolicfunctions werefit to the indifference points sepa-rately for the control(dashed lines)and episodic(solid lines,filled circles)conditions,and thebest-fitting k-parameters(discount rates)and R2values are shown for each subject.The log-trans-formed difference between discount rates wastaken as a measure of the effect of the episodictags on choice preferences.(B)Robust regressionrevealed an association between log-differences indiscount rates and imagery scores obtained frompostscan ratings(see text).(C)RTs were signifi-cantly modulated by option value(main effectvalue p<0.001)with faster responses in trialswith a value of the delayed reward higher thanthe20V reference amount.Note that althoughseven delays were used for each condition,somedata points are missing,e.g.,onlyfive delay indif-ference points for the episodic condition areplotted for sub20.This indicates that,for the twolongest delays,this subject never chose the de-layed reward.***p<0.005.Error bars=SEM.Neuron Episodic Modulation of Delay Discounting140Neuron66,138–148,April15,2010ª2010Elsevier Inc.Episodic Tags Activate the Future Thinking NetworkWe first analyzed differences in the condition regressors without parametric pared to those of the control condi-tion,BOLD responses to the presentation of the delayed reward in the episodic condition yielded highly significant activations (corrected for whole-brain volume)in an extensive network of brain regions previously implicated in episodic future thinking (Addis et al.,2007;Schacter et al.,2007;Szpunar et al.,2007)(see Figure 3and Table S2),including retrosplenial cortex (RSC)/PCC (peak MNI coordinates:À6,À54,14,peak z value =6.26),left lateral parietal cortex (LPC,À44,À66,32,z value =5.35),and vmPFC (À8,34,À12,z value =5.50).Distributed Neural Coding of Subjective ValueWe then replicated previous findings (Kable and Glimcher,2007;Kable and Glimcher,2010;Peters and Bu¨chel,2009)using a conjunction analysis (Nichols et al.,2005)searching for regions showing a positive correlation between the height of the BOLD response and subjective value in the control and episodic condi-tions in a parametric analysis (Figure 4A and Table S3).Note that this is a conservative analysis that requires that a given voxel exceed the statistical threshold in both contrasts separately.This analysis revealed clusters in the lateral orbitofrontal cortex (OFC,À36,50,À10,z value =4.50)and central OFC (À18,12,À14,z value =4.05),bilateral VS (right:10,8,0,z value =4.22;left:À10,8,À6,z value =3.51),mPFC (6,26,16,z value =3.72),and PCC (À2,À28,24,z value =4.09),representing subjective (discounted)value in both conditions.We next analyzed the neural tag effect,i.e.,regions in which the subjective value correlation was greater for the episodic condi-tion as compared with the control condition (Figure 4B and Table S4).This analysis revealed clusters in the left LPC (À66,À42,32,z value =4.96,),ACC (À2,16,36,z value =4.76),left dorsolateral prefrontal cortex (DLPFC,À38,36,36,z value =4.81),and right amygdala (24,2,À24,z value =3.75).Finally,we performed a triple-conjunction analysis,testing for regions that were correlated with subjective value in both conditions,but in which the value correlation increased in the episodic condition.Only left LPC showed this pattern (À66,À42,30,z value =3.55,see Figure 4C and Table S5),the same region that we previously identified as delay-specific in valuation (Petersand Bu¨chel,2009).There were no regions in which the subjective value correlation was greater in the control condition when compared with the episodic condition at p <0.001uncorrected.ACC Valuation Signals and Functional Connectivity Predict Interindividual Differences in Discount Function ShiftsWe next correlated differences in the neural tag effect with inter-individual differences in the size of the behavioral tag effect.To this end,we performed a simple regression analysis in SPM5on the single-subject contrast images of the neural tag effect (i.e.,subjective value correlation episodic >control)using the behavioral tag effect [log(k control )–log(k episodic )]as an explana-tory variable.This analysis revealed clusters in the bilateral ACC (right:18,34,18,z value =3.95,p =0.021corrected,left:À20,34,20,z value =3.52,Figure 5,see Table S6for a complete list).Coronal sections (Figure 5C)clearly show that both ACC clusters are located in gray matter of the cingulate sulcus.Because ACC-limbic interactions have previously been impli-cated in the control of choice behavior (Floresco and Ghods-Sharifi,2007;Roiser et al.,2009),we next analyzed functional coupling with the right ACC from the above regression contrast (coordinates 18,34,18,see Figure 6A)using a psychophysiolog-ical interaction analysis (PPI)(Friston et al.,1997).Note that this analysis was conducted on a separate first-level GLM in which control and episodic trials were modeled as 10s miniblocks (see Experimental Procedures for details).We first identified regions in which coupling with the ACC changed in the episodic condition compared with the control condition (see Table S7)and then performed a simple regression analysis on these coupling parameters using the behavioral tag effect as an explanatory variable.The tag effect was associated with increased coupling between ACC and hippocampus (À32,À18,À16,z value =3.18,p =0.031corrected,Figure 6B)and ACC and left amygdala (À26,À4,À26,z value =2.95,p =0.051corrected,Figure 6B,see Table S8for a complete list of activa-tions).The same regression analysis in a second PPI with the seed voxel placed in the contralateral ACC region from the same regression contrast (À20,34,22,see above)yielded qual-itatively similar,though subthreshold,results in these same structures (hippocampus:À28,À32,À6,z value =1.96,amyg-dala:À28,À6,À16,z value =1.97).Experiment 2We conducted an additional behavioral experiment to address a number of alternative explanations for the observed effects of tags on choice behavior.First,it could be argued thatepisodicFigure 3.Categorical Effect of Episodic Tags on Brain ActivityGreater activity in lateral parietal cortex (left)and posterior cingulate/retrosplenial and ventro-medial prefrontal cortex (right)was observed in the episodic condition compared with the control condition.p <0.05,FWE-corrected for whole-brain volume.NeuronEpisodic Modulation of Delay DiscountingNeuron 66,138–148,April 15,2010ª2010Elsevier Inc.141tags increase subjective certainty that a reward would be forth-coming.In Experiment 2,we therefore collected postscan ratings of reward confidence.Second,it could be argued that events,always being associated with a particular date,may have shifted temporal focus from delay-based to more date-based processing.This would represent a potential confound,because date-associated rewards are discounted less than delay-associated rewards (Read et al.,2005).We therefore now collected postscan ratings of temporal focus (date-based versus delay-based).Finally,Experiment 1left open the question of whether the tag effect depends on the temporal specificity of the episodic cues.We therefore introduced an additional exper-imental condition that involved the presentation of subject-specific temporally unspecific future event cues.These tags (henceforth referred to as unspecific tags)were obtained by asking subjects to imagine events that could realistically happen to them in the next couple of months,but that were not directly tied to a particular point in time (see Experimental Procedures ).Episodic Imagery,Not Temporal Specificity,Reward Confidence,or Temporal Focus,Predicts the Size of the Tag EffectIn total,data from 16participants (9female)are included.Anal-ysis of pretest ratings confirmed that temporally unspecific and specific tags were matched in terms of personal relevance,arousal,valence,and preexisting associations (all p >0.15).Choice preferences were again well described by hyperbolic functions (median R 2control =0.84,unspecific =0.81,specific =0.80).We replicated the parametric tag effect (i.e.,increasing effect of tags on discount rates with increasing posttest imagery scores)in this independent sample for both temporally specific (p =0.047,Figure 7A)and temporally unspecific (p =0.022,Figure 7A)tags,showing that the effect depends on future thinking,rather than being specifically tied to the temporal spec-ificity of the event cues.Following testing,subjects rated how certain they were that a particular reward would actually be forth-coming.Overall,confidence in the payment procedure washighFigure 4.Neural Representation of Subjective Value (Parametric Analysis)(A)Regions in which the correlation with subjective value (parametric analysis)was significant in both the control and the episodic conditions (conjunction analysis)included central and lateral orbitofrontal cortex (OFC),bilateral ventral striatum (VS),medial prefrontal cortex (mPFC),and posterior cingulate cortex(PCC),replicating previous studies (Kable and Glimcher,2007;Peters and Bu¨chel,2009).(B)Regions in which the subjective value correlation was greater for the episodic compared with the control condition included lateral parietal cortex (LPC),ante-rior cingulate cortex (ACC),dorsolateral prefrontal cortex (DLPFC),and the right amygdala (Amy).(C)A conjunction analysis revealed that only LPC activity was positively correlated with subjective value in both conditions,but showed a greater regression slope in the episodic condition.No regions showed a better correlation with subjective value in the control condition.Error bars =SEM.All peaks are significant at p <0.001,uncorrected;(A)and (B)are thresholded at p <0.001uncorrected and (C)is thresholded at p <0.005,uncorrected for display purposes.NeuronEpisodic Modulation of Delay Discounting142Neuron 66,138–148,April 15,2010ª2010Elsevier Inc.(Figure 7B),and neither unspecific nor specific tags altered these subjective certainty estimates (one-way ANOVA:F (2,45)=0.113,p =0.894).Subjects also rated their temporal focus as either delay-based or date-based (see Experimental Procedures ),i.e.,whether they based their decisions on the delay-to-reward that was actually displayed,or whether they attempted to convert delays into the corresponding dates and then made their choices based on these dates.There was no overall significant effect of condition on temporal focus (one-way ANOVA:F (2,45)=1.485,p =0.237,Figure 7C),but a direct comparison between the control and the temporally specific condition showed a significant difference (t (15)=3.18,p =0.006).We there-fore correlated the differences in temporal focus ratings between conditions (control:unspecific and control:specific)with the respective tag effects (Figure 7D).There were no correlations (unspecific:p =0.71,specific:p =0.94),suggesting that the observed differences in discounting cannot be attributed to differences in temporal focus.High-Imagery,but Not Low-Imagery,Subjects Adjust Their Discount Function in an Episodic ContextFor a final analysis,we pooled the samples of Experiments 1and 2(n =46subjects in total),using only the temporally specific tag data from Experiment 2.We performed a median split into low-and high-imagery participants according to posttest imagery scores (low-imagery subjects:n =23[15/8Exp1/Exp2],imagery range =1.5–3.4,high-imagery subjects:n =23[15/8Exp1/Exp2],imagery range =3.5–5).The tag effect was significantly greater than 0in the high-imagery group (t (22)=2.6,p =0.0085,see Figure 7D),where subjects reduced their discount rate by onaverage 16%in the presence of episodic tags.In the low-imagery group,on the other hand,the tag effect was not different from zero (t (22)=0.573,p =0.286),yielding a significant group difference (t (44)=2.40,p =0.011).DISCUSSIONWe investigated the interactions between episodic future thought and intertemporal decision-making using behavioral testing and fMRI.Experiment 1shows that reward delay dis-counting is modulated by episodic future event cues,and the extent of this modulation is predicted by the degree of sponta-neous episodic imagery during decision-making,an effect that we replicated in Experiment 2(episodic tag effect).The neuroi-maging data (Experiment 1)highlight two mechanisms that support this effect:(1)valuation signals in the lateral ACC and (2)neural coupling between ACC and hippocampus/amygdala,both predicting the size of the tag effect.The size of the tag effect was directly related to posttest imagery scores,strongly suggesting that future thinking signifi-cantly contributed to this effect.Pooling subjects across both experiments revealed that high-imagery subjects reduced their discount rate by on average 16%in the episodic condition,whereas low-imagery subjects did not.Experiment 2addressed a number of alternative accounts for this effect.First,reward confidence was comparable for all conditions,arguing against the possibility that the tags may have somehow altered subjec-tive certainty that a reward would be forthcoming.Second,differences in temporal focus between conditions(date-basedFigure 5.Correlation between the Neural and Behavioral Tag Effect(A)Glass brain and (B and C)anatomical projection of the correlation between the neural tag effect (subjective value correlation episodic >control)and the behav-ioral tag effect (log difference between discount rates)in the bilateral ACC (p =0.021,FWE-corrected across an anatomical mask of bilateral ACC).(C)Coronal sections of the same contrast at a liberal threshold of p <0.01show that both left and right ACC clusters encompass gray matter of the cingulate gyrus.(D)Scatter-plot depicting the linear relationship between the neural and the behavioral tag effect in the right ACC.(A)and (B)are thresholded at p <0.001with 10contiguous voxels,whereas (C)is thresholded at p <0.01with 10contiguousvoxels.Figure 6.Results of the Psychophysiolog-ical Interaction Analysis(A)The seed for the psychophysiological interac-tion (PPI)analysis was placed in the right ACC (18,34,18).(B)The tag effect was associated with increased ACC-hippocampal coupling (p =0.031,corrected across bilateral hippocampus)and ACC-amyg-dala coupling (p =0.051,corrected across bilateral amygdala).Maps are thresholded at p <0.005,uncorrected for display purposes and projected onto the mean structural scan of all participants;HC,hippocampus;Amy,Amygdala;rACC,right anterior cingulate cortex.NeuronEpisodic Modulation of Delay DiscountingNeuron 66,138–148,April 15,2010ª2010Elsevier Inc.143。
拇指血流灌注指数试验与改良Allen试验的比较
硕士学位论文论 文 题 目: 拇指血流灌注指数试验与改良Allen试验的比较Evaluation of the patency of the hand collateralarteries with thumb Perfusion Index test:Comparison with the modified Allen’s test研 究 生 姓 名: 吴阳指导教师: 刘松学科专业: 麻醉学研究方向: 麻醉学临床技能训练与研究论文工作时间: 2015年6月至2016年12月目录中文摘要 (1)英文摘要 (2)正 文 (3)前 言 (3)资料与方法 (7)结 果 (10)讨 论 (15)结 论 (22)参考文献 (23)致 谢 (33)附录A (34)附录B (44)拇指血流灌注指数试验与改良Allen试验的比较中文摘要目的:探讨拇指血流灌注指数(Perfusion Index,PI)试验替代改良Allen试验(modified Allen's test,MAT)评价掌部组织侧支循环血流灌注的可行性。
方法:选择1108例拟行择期手术并需要经桡动脉入路进行有创动脉压力监测的患者,在桡动脉穿刺前先后用MAT和拇指PI值试验分别评价患者试验侧掌部组织侧支循环血流灌注的情况,并将两种试验方法结果进行统计学比较和分析。
结果:在1108例患者中MAT阴性患者1035例(93.41%),阳性患者73例(6.59%);拇指PI值试验阴性患者1090例(98.38%),其中包括57例MAT阳性患者,阳性患者18例(1.62%)。
拇指PI值试验阴性患者行经该侧桡动脉入路进行有创动脉压力监测,两种试验方法结果进行卡方检验,差异有统计学意义(x2=51.27, P<0.05)。
两种试验方法影响因素进行logistic回归分析发现两种试验方法结果阳性率均与年龄和性别有相关性(P<0.05)。
结论:在本研究中用拇指PI值试验筛选出1.62%的患者不宜行经桡动脉入路进行有创动脉压力监测。
阿莫西林质量标准USP197
〈197〉 SPECTROPHOTOMETRIC IDENTIFICATION TESTS Spectrophotometric tests contribute meaningfully toward the identification of many compendial chemical substances. The test procedures that follow are applicable to substances that absorb IR and/or UV radiation (see Mid-Infrared Spectroscopy 〈854〉 and Ultraviolet-Visible Spectroscopy 〈857〉).The IR absorption spectrum of a substance, compared with that obtained concomitantly for the corresponding USP Reference Standard, provides perhaps the most conclusive evidence of the identity of the substance that can be realized from any single test. The UV absorption spectrum, on the other hand, does not exhibit a high degree of specificity. Conformance with both IR absorption and UV absorption test specifications, as called for in a large proportion of compendial monographs, leaves little doubt, if any, regarding the identity of the specimen under examination.INFRARED ABSORPTIONSeven methods are indicated for the preparation of previously dried test specimens and Reference Standards for analysis. The reference 〈197K〉in a monograph signifies that the substance under examination is mixed intimately with potassium bromide. The reference 〈197M〉in a monograph signifies that the substance under examination is finely ground and dispersed in mineral oil. The reference 〈197F〉 in a monograph signifies that the substance under examination is suspended neat between suitable (for example, sodium chloride or potassium bromide) plates. The reference 〈197S〉signifies that a solution of designated concentration is prepared in the solvent specified in the individual monograph, and the solution is examined in 0.1-mm cells unless a different cell path length is specified in the individual monograph. The reference 〈197A〉 signifies that the substance under examination is intimately in contact with an internal reflection element for attenuated total reflectance (ATR) analysis. The reference 〈197E〉 signifies that the substance under examination is pressed as a thin sample against a suitable plate for IR microscopic analysis. The reference 〈197D〉in a monograph signifies that the substance under examination is mixed intimately with an IR-transparent material and transferred to a sample container for diffuse reflection (DR) analysis. The ATR 〈197A〉and the 〈197E〉techniques can be used as alternative methods for 〈197K〉, 〈197M〉, 〈197F〉, and 〈197S〉where testing is performed qualitatively and the Reference Standard spectra are similarly obtained.Record the spectra of the test specimen and the corresponding USP Reference Standard over the range from about 2.6 µm to 15 µm (3800 cm–1 to 650 cm–1) unless otherwise specified in the individual monograph. The IR absorption spectrum of the preparation of the test specimen, previously dried under cond itions specified for the corresponding Reference Standard unless otherwise specified, or unless the Reference Standard is to be used without drying, exhibits maxima only at the same wavelengths as that of a similar preparation of the corresponding USP Reference Standard. Differences that may be observed in the spectra so obtained sometimes are attributed to the presence of polymorphs, which are not always acceptable (see Procedure under 〈854〉). Unless otherwise directed in the individual monograph, therefore, continueas follows. If a difference appears in the IR spectra of the analyte and the standard, dissolve equal portions of the test specimen and the Reference Standard in equal volumes of a suitable solvent, evaporate the solution to dryness in similar containers under identical conditions, and repeat the test on the residues.ULTRA VIOLET ABSORPTIONThe reference 〈197U〉in a monograph signifies that a test solution and a Standard solution are examined spectrophotometrically, in 1-cm cells, over the spectral range from 200 to 400 nm unless otherwise specified in the individual monograph. Dissolve a portion of the substance under examination in the designated Medium to obtain a test solution having the concentration specified in the monograph for Solution. Similarly prepare a Standard solution containing the corresponding USP Reference Standard.Record and compare the spectra concomitantly obtained for the test solution and the Standard solution. Calculate absorptivities and/or absorbance ratios where these criteria are included in an individual monograph. Unless otherwise specified, absorbances indicated for these calculations are those measured at the maximum absorbance at about the wavelength specified in the individual monograph. Where the absorbance is to be measured at about the specified wavelength other than that of maximum absorbance, the abbreviations (min) and (sh) are used to indicate a minimum and shoulder, respectively, in an absorption spectrum. The requirements are met if the UV absorption spectra of the test solution and the Standard solution exhibit maxima and minima at the same wavelengths and absorptivities and/or absorbance ratios are within specified limits.Auxiliary Information—Please check for your question in the FAQs before contacting USP.Topic/Question Contact Expert CommitteeGeneral Chapter Edmond Biba,Ph.D.Scientific Liaison-General Chapters (301) 230-3270(GCCA2015) General Chapters-Chemical Analysis 2015USP41–NF36 Page 6101Previously Appeared In: Pharmacopeial Forum: V olume No. 42(5)。
Yokogawa DL系列差分探测器(Model 700924)用户手册说明书
User's ManualThank you for purchasing the Differential Probe (Model 700924) for the DL series. To ensure correct use, please read this manual thoroughly before beginning operation. After reading the manual, keep it in a convenient location for quick reference whenever a question arises during operation.IM 700924-01E IM 700924-01EModel 700924Differential Probe for the DL SeriesYOKOGAWA ELECTRIC CORPORATION, Communication & Measurement Business Headquarters Phone: (81)-422-52-67689-32, Nakacho 2-chome, Musashino-shi, Tokyo, 180-8750 JAPANYOKOGAWA CORPORATION OF AMERICA Phone: (1)-770-253-70002 Dart Road, Newnan, Ga. 30265-1094, U.S.A.YOKOGAWA EUROPE B.V. Phone: (31)-33-4641858Databankweg 20, 3821 AL, Amersfoort, THE NETHERLANDS YOKOGAWA ENGINEERING ASIA PTE. LTD. Phone: (65)-624199335 Bedok South Road, Singapore 469270, SINGAPORE7th Edition7th Edition : October 2007 (YK)All Rights Reserved, Copyright © 2007, Yokogawa Electric CorporationSafety PrecautionsMake sure to comply with the safety precautions mentioned hereafter when handling the probe.Yokogawa Electric Corporation assumes no responsibility for any consequences resulting from failure to comply with these safety precautions. Also, read the User’s Manual of the measuring instrument thoroughly so that you are fully aware of its specifications and handling, before starting to use the probe.The following symbols are used on this instrument.Warning: handle with care. Refer to the user’s manual or service manual. This symbol appears on dangerous locations on the instrument which require special instructions forproper handling or use. The same symbol appears in the corresponding place in the manual to identify those instructions. Risk of electric shockMake sure to comply with the following safety precautions in order to prevent accidents such as an electric shock which impose serious health risks to the user and damage to theGrounding of the measuring instrumentThe protective grounding terminal of the measuring instrument must be connected to ground.Earth cable of the probeMake sure to connect the earth cable of the probe to the ground (grounding potential). Do not operated with suspected failuresIf you suspect that there is damage to this probe, have it inspect by a service personnel.Observe maximum working voltageTo avoid any injury,do not use the probe above 1400 Vpeak between each input lead and earth or between the two inputs.This voltage rating applies to both 1/100 and 1/1000 settings.Must be groundedThis probe must be grounded with the BNC shell and an auxiliary grounding terminal, through the grounding conductor of the power cord of the measuring instrument or other appropriate grounding conductor. Before making connections to the input terminals of the product, ensure that the output connector is attached to the BNC connector of the measuring instrument and the auxiliary grounding terminal is connected to a proper ground, while the measuring instrument is properly grounded.Do not operate without coverTo avoid electric shock or fire hazard, do not operate this probe with the cover removed.Do not operate in wet/damp conditionsTo avoid electric shock, do not operate this probe in wet or damp conditions.Do not operate in explosive atmosphereTo aviod injury or fire hazard, do not operate this probe in an explosive atmosphere.Avoid exposed circuitryTo avoid injury, remove jewelry such as rings, watches, and other metallic objects. Do not touch exposed connections and components when power is present.CAUTIONMaximum input voltageDo not apply any voltages exceeding the maximum input voltage to the probe.Correct use of the power supplyPower the probe with either 4 AA dry cells, a 6 VDC/200 mA or 9 VDC/150 mA externalpower supply, or by connecting the probe’s power cable to a probe power supply terminal on a DL series measuring instrument or to the 700938 or 701934. Operating the probe under a power supply greater than the voltage specified above may cause damage to the instrument. Connecting the external power supply to the probeAlways turn OFF the probe’s power switch when connecting or disconnecting the external power supply. Also, do not install the dry cells when using an external power supply.Operating environment limitationsSee below for operating environment limitations.CAUTIONThis product is a Class A (for industrial environments) product. Operation of this product in a residential area may cause radio interference in which case the user is required to correct the interference.Waste Electrical and Electronic Equipment (WEEE), Directive 2002/96/EC (This directive is only valid in the EU.)This product complies with the WEEE Directive (2002/96/EC) marking requirement. This marking indicates that you must not discard this electrical/electronic product in domestic household waste.Product CategoryWith reference to the equipment types in the WEEE directive Annex 1, this product is classified as a “Monitoring and Control instrumentation” product.Do not dispose in domestic household waste. When disposing products in the EU, contact your local Yokogawa Europe B. V. office.The Following Symbols are Used in this Manual.Improper handling or use can lead to injury to the user or damage to the instrument. This symbol appears on the instrument to indicate that the user must refer to theuser’s manual for special instructions. The same symbol appears in the corresponding place in the user’s manual to identify those instructions. In the manual, the symbol is used in conjunction with the word “WARNING” or “CAUTION.”WARNING Calls attention to actions or conditions that could cause serious or fatal injury to theuser, and precautions that can be taken to prevent such occurrences.CAUTION Calls attentions to actions or conditions that could cause light injury to the user ordamage to the instrument or user’s data, and precautions that can be taken to prevent such occurrences.NoteCalls attention to information that is important for proper operation of the instrument.1 DescriptionBy using this device, oscilloscopes with single-ended input can be easily used as oscilloscopes with differential inputs.2 Appearance22 Pinchers tips3 Ground extention lead (length = 100 cm)Power cable*Pinchers tip B9852MJ Black: B9852MM, Red: B9852MN* Power can be supplied from the DL, 700938,or 701934.Optional Accessories (Sold Separately)3 Installing/Replacing the Dry CellsShift the lid at the back side of the probe and install/replace the four dry cells. The dry cells are not installed on receipt of the instrument.4 Operation1. Install four AA cells. When using an external power supply, do not install the dry cells. Supply power only through the external power supply.2. Simply plug-in the BNC output connector to the vertical input of a oscilloscope, and connect the auxiliary grounding terminal to a proper ground. If necessary, use a ground extention lead.3. Select the proper range setting. For higher resolution and less noise when measuring signals below 350V, switch the attenuation to 1/100. Otherwise, set the attenuation to 1/1000 when measuring signals above 350V.4. If the offset voltage is large, short the top of input leads, and turn the ADJUST variable resistor (DC voltage adjustment) using a flat-head screwdriver to adjust the offset voltage.• To protect against electric shock the ground side of the output cable (the shielded side of the BNC connector) must be grounded.• Make sure to avoid an electric shock when connecting the probe to the object ofmeasurement. Do not remove the probe from the measuring instrument after the object of measurement is connected.• When disconnecting the probe BNC output connector, first turn OFF the power to the circuit under measurement. Then, disconnect the probe from the high voltage parts of the circuit under measurement.• When replacing batteries or connecting an external power supply, first turn OFF the power to the circuit under measurement. Then, remove the input lead from the circuit under measurement.CAUTION• This probe is to carry out differential measurement between two points on the circuit under measurement. This probe is not for electrically insulating the circuit under measurement and the measuring instrument.• Use a soft cloth to clean the dirt. Prevent damage to the probe. Avoid immersing the probe, using abrasive cleaners, and using chemicals contains benzene or similar solvents.Note• Connect the BNC connector to the input terminal of the oscilloscope and for two pointmeasurement (differential measurement), connect both input leads. Because the performance declines in case you carry out measurements with only one input lead connected, make sure to always connect both.• Accurate measurement may not be possible near objects with strong electric fields (such as cordless equipment, transformers, or circuits with large currents).5 SpecificationsItemSpecificationsFrequency bandwidth *1DC to 100 MHz (−3 dB)Input typeBalancing difference inputAttenuation ratioswitched ratios of 100:1 and 1000:1Output offset voltage *1 *2±7.5 mVInput resistance and capacity 4 M Ω + 10 pF each side to groundDifferential allowable voltage ±1400 V (DC + ACpeak) or 1000 Vrms at 1000:1 attenuation (between + − terminal)±350 V (DC + ACpeak) or 250 Vrms at 100:1 attenuation Max common mode voltage ±1400 V (DC + ACpeak) or 1000 Vrms Max input voltage(to ground)±1400 V (DC + ACpeak) or 1000 VrmsCMRR (typical)*160 Hz: less than −80 dB; 1 MHz: less than −50 dB Output voltage *1±3.5 V (DC + ACpeak)Output impedance Using 1 M Ω input system oscilloscopeGain accuracy *1±2% (common mode voltage ≤ 400 V and ≥ −400 V)±3% (common mode voltage ≤ 1000 V and ≥ −1000 V)Operating environment 5 to 40°C, 25 to 85% (no condensation)Storage environment −30 to 60°C, 25 to 85% (no condensation)Operating altitude 2,000 m or lessPower requirements *3Internal battery: four dry cells (AA, R6)External power supply:6 VDC/200 mA or more, or 9 VDC/150 mA or more.From the DL series instrument’s probe power supply, 700938, or 701934 using the probe’s power supply cable. Cell life time In continuous duty, approx. 2 hoursDimensions 207 mm × 83 mm × 38 mm (excluding connector and cable)WeightApprox. 800 g ( excluding the dry cells)Withstanding voltage 2000 VACrms (between input terminal and BNC-ground), for 5 minutesSafety standardsComplying standards EN61010-031Measurement category III *4: 1400 V (DC + ACpeak)Pollution degree 2*5EmissionComplying standardsEN61326, EN55011, EN61000-3-2, EN61000-3-3This product is a Class A (for industrial environment) product. Operation of this product in a residential area may cause radio interference in which case the user is required to correct the interference.ImmunityComplying standards EN61326*1 When the power supply voltage from the dry cells is 5 V or more, or when using an external power supply.*2 Ambient temperature 23±5°C*3 When the capacity of dry cells goes down LED blinks. In such a case, replace the dry cells. Also, do not install the dry cells when using an external power supply.*4This equipment is for measurement category III (CAT III). Do not use it with measurement category IV (CAT IV). CAT III applies to measurement of the distribution level, that is , building wiring, fixed installations. CAT IV applies to measurement of the primary supply level, that is, overhead lines, cable systems, and so on.*5 Pollution degree applies to the degree of adhesion of a solid, liquid, or gas which deteriorates withstandvoltage or surface resistivity. Pollution degree 2 applies to normal indoor atmospheres (with only non-conductive pollution).Input voltage deratingFrequency (Hz)0.1 M1010010001400 1 M 10 M 100 M M a x i n p u t v o l t a g e (V )1981。
瑕积分敛散性的判别方法和应用
本文给出瑕积分收敛性的判断方法,并将其运用到瑕积分的解题之中.判断瑕积分收敛的方法主要有定义法、比较法和柯西判别法、狄利克雷判别法和阿贝尔判别法,被积函数的原函数已知或易求的用定义法;满足狄利克雷判别法条件的函数用狄利克雷判别法;满足阿贝尔判别法条件的函数用阿贝尔判别法;含有正弦、余弦等有界函数或绝对收敛的函数可考虑用比较法来判断.依据两类含参量反常积分可以互化的关系,从含参量无穷限积分的一致收敛的判定定理出发,给出了含参量瑕积分一致收敛性的判定定理及其证明.最后给出了瑕积分计算可简化的两种形式,以便能够更方便更准确的计算出瑕积分的值.关键词:瑕积分;收敛;含参量瑕积分;含参量无穷限积分;一致收敛In this paper, we give the flaw integral convergence judgment method, and apply to solving of flaw integral. Judging method of flaw integral convergence are mainly definition method, comparative method and cauchy-criterion principle. Definition method can be used when integrand is easly obtained. Dirichlet test and Abel's test are carried out when some conditions are satisfied. Comparative method can be used when sine or cosine function and so on, bounded function is included.By means of the relation between the two abnormality integral containing parameters, the judgment theorem of consistent astringency of flaw integral containing parameters is deduced from the judgment theorem of consistent astringency infinite integral containing parameters. Some typical examples are given to illuminate the application of the obtained judgment and theorem. This paper presents some conditions under which defect integral can be computed as common intergral.We prove that defect integral canbe computed as common intergral if the original function of the integrand is continuous of bounded on the integeral interval.Key words:Flaw integral; Convergence; Flaw integral containing parameters; Infinite integral containing parameters; Consistent astringency目录摘要 (I)Abstract (II)1 引言 (1)2 瑕积分敛散性的判别方法和应用 (2)2.1 瑕积分的定义 (2)2.2 瑕积分的性质 (3)2.3 瑕积分的收敛判别法 (4)2.4 瑕积分收敛判别法的应用举例 (5)2.5 柯西判别法的延伸及应用 (6)3 含参量瑕积分一致收敛的判定和应用 (9)3.1 含参量瑕积分的定义 (9)3.2 含参量瑕积分一致收敛的判别法 (9)3.3 含参量瑕积分判定收敛法的应用 (13)4 瑕积分计算的简化 (16)4.1 瑕积分计算可简化的第一种情形 (16)4.2 瑕积分计算可简化的第二种情形 (18)5 总结和展望 (21)参考文献 (22)致谢 ........................................................................................... 错误!未定义书签。
马尔斯塔德产品指南:指示器拱架、对比器拱架和旋转测试仪说明书
4413050 4413051 4413052
Features
• A stable Height Stand for electronic measurement,
• Fine adjustment in the base allows easy operator set-up, even at high magnification. Up to 3.8 mm / .150“ adjustment when arms fully extended.
2
Weight
kg 2.2
Order no.* Mount dia.
8H7
4417000
Order no.* Mount dia.
3/8”
4417050
Order no. wooden
case.
4416001
8- 4
MarStand. Indicator Stands, Comparator Stands, Run out Testing Instruments
34 ø18
ø14
220
285
Features
• Support arm with one joint • Base has a powerful
ON/OFF permanent magnet • Magnetic force is active
across the surfaces and the V-shaped bottom plus the front of the base • Post and support arm are made from stainless steel • Support arm can be finely adjusted • Indicating instrument can be rotated through ± 90°
OPTICAL ELEMENT, OPTICAL ELEMENT ARRAY, DISPLAY DE
专利名称:OPTICAL ELEMENT, OPTICAL ELEMENTARRAY, DISPLAY DEVICE, AND ELECTRONICAPPARATUS发明人:Kenichi Takahashi,Hidehiko Takanashi申请号:US13676318申请日:20121114公开号:US20130128337A1公开日:20130523专利内容由知识产权出版社提供专利附图:摘要:An optical element includes: a first electrode and a second electrode that are arranged opposite each other, in which the first electrode allows part of incident light topass therethrough and reflects another part of the incident light, and the second electrode reflects light that has passed through the first electrode; a first dielectric film and a second dielectric film covering the first electrode and the second electrode, respectively; and a first medium and a second medium each interposed and sealed in a space containing a cavity portion between the first dielectric film and the second dielectric film, in which the first medium and the second medium have refractive indices different from one another, and one of the first medium and the second medium is a polar liquid.申请人:Sony Corporation地址:Tokyo JP国籍:JP更多信息请下载全文后查看。
动脉瘤夹钳招标参数要求
动脉瘤夹钳招标参数要求以下是动脉瘤夹钳招标参数要求的英文和中文描述:英文:Aneurysm Clip Applicator Tender ParametersMaterial: The aneurysm clip applicator shall be made of high-quality medical stainless steel or titanium alloy, ensuring durability and biocompatibility.Dimensions: The applicator shall have precise dimensions, suitable for various aneurysm sizes, with adjustable or interchangeable jaws for flexibility.Handle Design: The handle should be ergonomically designed for easy operation, providing a secure and comfortable grip for the surgeon.Mechanism: The clamping mechanism should be smooth and reliable, ensuring accurate and consistent aneurysm clipping.Sterilization: The aneurysm clip applicator must be capable of being sterilized using standard medical sterilization methods, ensuring patient safety.Packaging: The applicator shall be packaged in a sterile, tamper-evident package, with clear instructions for use and handling.Compliance: The product shall comply with all relevant international medical device standards and regulations, including but not limited to ISO standards and FDA requirements.中文:动脉瘤夹钳招标参数要求材质:动脉瘤夹钳应采用优质医用不锈钢或钛合金制成,以确保其耐用性和生物相容性。
CONTRACER CV-1000 2000 数字高精度轮廓测量仪说明书
Digital analysis type that feature excellent portability and versatility
CONTRACER CV-1000/2000
Versatile combinations to suit different applications
˙Choose the combination that best suits your
Narrow measurement range and difficult setup.
Resolution
Measuring range
Same Resolution Entire measuring range
Low
Wide
The Circular Scale
Operators are free from bothersome operations such as the measurement magnification switching and calibration for each magnification required for analog instruments.
Traverse linearity (with the X axis horizontal)
138µm / 2" (3.5µm/50mm)
138µm / 4" (3.5µm/100mm)
Z axis resolution
0.4µm
0.5µm
Drive speed
Measuring Moving
(0.2/0.5mm/s) (0.2/1.0mm/s and manual)
High resolution improves measuring accuracy.
剪梳[发明专利]
专利名称:剪梳
专利类型:发明专利
发明人:盖伊·埃德蒙德·沃特斯申请号:CN88106633.8
申请日:19880910
公开号:CN1031811A
公开日:
19890322
专利内容由知识产权出版社提供
摘要:提出一种剪梳,其中有一个下梳,上有凹陷容纳 一个插件。
下梳有齿,插件两侧有齿。
每一组插件的 齿提供两个切割部,因此插件可以颠倒,并可将两边 对换,从而可将一个切割部和上切割梳配合,用于剪 羊毛。
插件上覆以氮化钛或碳化钛,下梳有孔容纳螺 丝,将插件在凹陷中夹持。
申请人:盖伊·埃德蒙德·沃特斯
地址:澳大利亚维多利亚州
国籍:AU
代理机构:中国专利代理有限公司
代理人:林东晖
更多信息请下载全文后查看。
Elkay Neptune 300系列洗手间陶瓷单孔顶部挂载洗手盆说明书
SPECIFICATIONSElkay Neptune Stainless Steel 25" x 22" x 6-1/16"Single Bowl Top Mount SinkModel(s) NE2525224In keeping with our policy of continuing product improvement, Elkay reserves the right to change product specifications without notice. Please visit for the most current version of Elkay product specification sheets. This specification describes an Elkay product with design, quality, and functional benefits to the user. When making a comparison of other producers’ offerings, be certain these features are not overlooked.Elkay REV 04212018 2222 Camden Court © 2018 Page 1 NE2525224 Oak Brook, IL 60523 NE2525224_spec.pdfPRODUCT SPECIFICATIONSElkay Neptune Stainless Steel 25" x 22" x 6-1/16", Single Bowl Top Mount Sink. Sink is manufactured from 23 gauge 300 seriesStainless Steel with a Buffed Satin finish, Center drain placement, and Bottom only spray.Cutout Dimensions for Top Mount Installation:24-3/8" x 21-3/8" (619mm x 543mm) with 1-1/2" (38mm) corner radiusNOTE: MUST BE ORDERED IN MULTIPLES OF 25AMERICAN PRIDE. A LIFETIME TRADITION.Like your family, the Elkay family has values and traditions that endure. For almost a century, Elkay has been a family-owned and operated company, providing thousands of jobs that support our families and communities.Product Compliance:ADA & ICC A117.1ASME A112.19.3/CSA B45.4 BUY AMERICAN ACTSinks are listed by IAPMO ® as meeting the applicablerequirements of the Uniform Plumbing Code ®, International Plumbing Code ®, and National Plumbing Code of Canada. Complies with ADA & ICC A117.1 accessibility requirements when installed according to the requirements outlined in these standards.Clean and Care Manual (PDF) Installation Instructions (PDF) Limited Lifetime Warranty (PDF)Installation Profile:PART:________________________________QTY: _____________ PROJECT:______________________________________________ CONTACT:______________________________________________ DATE:__________________________________________________ NOTES:_________________________________________________APPROVAL:_____________________________________________。
计量器具中英文对照
1. 量块gaugeblock2。
光滑极限量规plainlimit gauge3. 塞规pluggauge4. 环规ringgauge卡规snap gauge5. 塞尺feelergauge6. 钢直尺steelgauge7. 精密玻璃线纹尺precision glass linear scale8. 精密金属线纹尺precision metal linear scale9。
半径样板radiustemplate卡尺类1。
游标卡尺verniercaliper2. 带表卡尺dialcaliper3。
电子数显卡尺calliperwith electronic digital display4。
深度标游卡尺depthvernier caliper5。
电子数显深度卡尺depthcaliper with electronic digital display 6。
带表高度卡尺dialheight calliper7. 高度游标卡尺heightvernier caliper8. 电子数显高度卡尺heightcaliper with electronic digital9。
焊接检验尺calliperfor welding inspection千分尺类1. 测微头micrometerhead2。
外径千分尺externalmicrometer3. 杠杆千分尺micrometer with dial comparator4。
带计数器千分尺micrometer with counter5. 电子数显外径千分尺micrometer with electronic digital display6. 小测头千分尺smallanvil micrometer7。
尖头千分尺pointmicrometer8。
板厚千分尺sheetmetal micrometer9。
壁厚千分尺tubemicrometer10. 叶片千分尺blademicrometer11。
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ELEMENTARY COUNTEREXAMPLES TO KODAIRA VANISHING IN PRIME CHARACTERISTIC
arXiv:alg-geom/9604012v1 19 Apr 1996
N. Lauritzen and A. P. Rao Aarhus Universitet, ˚ Arhus, Denmark and University of Missouri, St.Louis, USA
∗ ∨
ELEMENTARY COUNTEREXAMPLES a vector bundle of rank n − 1. The surjection V ∨ ⊗k OP(V ) − → A∨ induces an inclusion of P(V )-schemes Y ֒→ P(V ) × P(V ∨ ). Let π1 , π2 be the two projections defined on P(V ) × P(V ∨ ). There is the natural map on the product
1991 Mathematics Subject Classification. 14F17, 14M17. Key words and phrases. Cohomology, line bundles, Kodaira vanishing.
2
N. LAURITZEN AND A. P. RAO
It would be interesting to see if such elementary calculations also yield examples to Raynaud’s second question. The example known so far [5] uses computer intensive calculations. Also the examples of this note are of dimension six or more (and with Picard group of rank three), whereas the example of Raynaud (and Mumford’s normal variety, earlier) is a surface. While the examples here are more elementary than Raynaud’s example, it would be nice to find other examples of smaller dimension (or with Picard group of rank two). Since it is only the penultimate H i (X, L−1 ) which is non-zero, this failure of Kodaira vanishing is not necessarily inherited by hyperplane sections. Both authors would like to thank the Tata Institute of Fundamental Research for it’s hospitality during the period in which this work was done. 1. Preliminaries 1.1. Let V be an n + 1-dimensional vector space over a field k . We will consider P(V ), P(∧2 V ∨ ) and P(V ∨ ). The tautological line (quotient) bundle of each will be denoted O (1, 0, 0), O(0, 1, 0) and O(0, 0, 1) respectively. So on P(V ), there is an exact sequence of vector bundles 0− →A− → V ⊗k OP(V ) − → O(1, 0, 0) − → 0. This identifies H 0 (P(V ), O(1, 0, 0) with V . If we fix a basis X0 , X1 , . . . , Xn for V and the dual basis Y0 , Y1 , . . . , Yn for V ∨ , the dual of the above sequence gives the homomorphism OP(V ) − → O (1, 0, 0) ⊗k V ∨ which determines the global section X i Yi .
Let X be a smooth projective variety of dimension m over an algebraically closed field of characteristic zero and let L be an ample line bundle on X . The Kodaira Vanishing Theorem [3] states that H i (X, L−1 ) = 0 for i = m. It is well known that the result is false in characteristic p > 0; Raynaud constructed [8] a smooth projective surface in positive characteristic with an ample line bundle for which Kodaira vanishing failed (Mumford [7] had earlier constructed a normal non-smooth projective surface counter-example). Raynaud posed two questions: (1) Are there counter-examples where the vanishing fails for a very ample line bundle? (2) Are there pairs (X, L) (X smooth projective, L ample) for which χi (L ⊗ ωX ) := hi (X, L ⊗ ωX ) − hi+1 (X, L ⊗ ωX ) + . . . is not always ≥ 0? The first author, studying proper homogeneous spaces in characteristic p [4][5], answered both questions affirmatively using methods from modular representation theory of algebraic groups. The object of this note is to generalize, via elementary algebraic geometry, the simplest counterexample ([1], Example 4) answering question (1) without using Jantzen’s sum formula from modular representation theory. The simplest of our examples is as follows: let Y be the incidence correspondence of points lying on planes in projective three space P(V ). There is a natural bundle G of rank 2 on Y such that the projectivization P(G ) of G is the variety of flags in V . Now let X = P(F ∗ G ) be the projectivization of F ∗ G (the Frobenius pullback of G .) Then X can be embedded in P(V ) × P(∧2 V ∨ ) × P(V ∨ ), and the line bundle L = O(1, 3, 1) is very ample on X and violates Kodaira vanishing (with H 5 (X, L−1 ) = 0).
1.2. Let Y be a scheme, and let E be a vector bundle of rank r on Y . Let X = P(E ) be the projectivized bundle. It comes with a morphism π : X − → Y , such that X is smooth over Y and X has a tautological line bundle Oπ (1) which appears in a sequence 0− →F − → π∗E − → Oπ (1) − → 0. ωX/Y can be identified with ∧r (π ∗ E ) ⊗ Oπ (−r ) ([2], III, Ex 8.4). 1.3. Let Y be a scheme over a field k of characteristic p = 0. The absolute Frobenius morphism F : Y − → Y is defined on the level of affine rings by mapping p the function a to a , and has the property that if L is a line bundle on Y , then F ∗L ∼ → L defining a section s, it pulls = Lp , and if there is a homomorphism OX − p back to a homomorphism OX − → L defining the section sp [6]. 2. The Example Let V be a vector space of dimension n + 1 over a field k of characteristic p = 0 where n ≥ 3 and p ≥ n − 1. On P(V ) there is the sequence of bundles 0− →A− → V ⊗k OP(V ) − → O(1, 0, 0) − → 0. Let Y = P(A∨ ), with the morphism α : Y − → P(V ). We have