地佐辛硬膜外与静脉用药在产科术后镇痛中的效果比较

地佐辛硬膜外与静脉用药在产科术后镇痛中的效果比较
刘心国;宿世玉;李佳慧
【期刊名称】《中国当代医药》
【年(卷),期】2015(22)20
【摘要】Objective To compare the clinical effect and adverse reactions of dezocine used in postoperative and intra-venous injection epidural analgesia after cesarean section. Methods 90 cases of elective cesarean section from June to December 2014 in our hospital were randomly divided into 3 groups,with 30 cases in each group.The group A was giv-en with dezocine 5 mg intravenous injection,group B with dezocine 5 mg was used in epidural analgesia,group C with saline 10 ml was used in epidural for control.The VAS scoring at postoperative 4,8,12,24 h was observed respectively. Various adveme reactions was recorded and postoperative satisfaction was compared. Results The VAS scores at post-operative 2 h had no statistical difference among the 3 groups (P>0.05);The VAS scores at postoperative 4 h in group A was lower than that of group C,with statistical difference (P<0.05);The VAS scores at postoperative 8,12 h in group B was lower than that of group A,with statistical difference
(P<0.05).There was no statistical difference among 3 groups at postoperative 24 h(P>0.05).The incidence rate of nausea and vomiting the group A and B was higher than that of group C;group B was higher than that of group A,with statistical difference (P<0.05). Conclusion Appropriate
concentrations of dezocine used in postoperative epidural analgesia after cesarean section has definite effect and less adverse reac-tions.%目的：探讨地佐辛在产科术后镇痛中，静脉用药与硬膜外用药镇痛的效果比较。

方法选择2014年6~12月于本院就诊的90例接受手术的产妇，随机分为A组、B组和对照组C组，每组30例。

A组采用术后静脉应用地佐辛5 mg镇痛，B组采用术后硬膜外应用地佐辛5 mg镇痛，对照组C组给予硬膜外推注生理盐水10 ml；比较3组术后各时间点的VAS评分，药物不良反应和术后满意度。

结果3组患者术后2 h的VAS评分比较，差异无统计学意义(P>0.05)；A组患者VAS评分在术后4 h明显低于对照组C组(P<0.05)；B组患者VAS评分在术后4、8、12 h时均低于对照组C组(P<0.05)；术后8、12 h时，B组患者VAS评分明显低于A组患者评分(P<0.05)，术后24 h时，3组患者VAS评分比较，差异无统计学意义(P>0.05)；A、B组患者术后无明显不良反应，C组患者出现2例术后寒战；A、B 组术后镇痛满意度好于C组；B组满意度好于A组。

结论地佐辛在产科术后镇痛中，硬膜外用药镇痛效果在时效方面较静脉用药更有优势，且患者满意度高。

【总页数】3页(P87-89)
【作者】刘心国;宿世玉;李佳慧
【作者单位】济南市第五人民医院麻醉科，济南 250022;济南市第五人民医院麻醉科，济南 250022;济南市第五人民医院麻醉科，济南 250022
【正文语种】中文
【中图分类】R971+.2
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