Class 2 Schizophrenia
E时代大学英语视听说教程4课件及答案 Unit 1 A Beautiful Mind
Part I Warm-up
Part II
In-Class Listening Understanding Short Conversations Understanding a Long Conversation Understanding a Passage Understanding News Reports
Report One Report Two Understanding a Movie Clip Speaking Self-Checking
Part Ⅲ After-Class Listening Task One Task Two Task Three
PartⅠ Warm-up
Listen to each sentence first and choose the right expressions from the four possible choices.
Part II In-Class Listening
Now you will hear five short conversations. After each conversation, you will hear a question. Listen carefully and choose the best answer from the four possible choices.
3. A. Patients with depression are extremely dangerous. B. Patients with depression may commit suicide. C. Patients with depression may buy something that is worth nothing. D. Patients with depression may lose others’ love towards them.
2-苏铁、银杏科
e.多数裸子植物具颈卵器
f. 胚珠裸露,不形成果实
Ginkgo biloba Pinus mugo
Gnetum gnemon
三、 裸子植物的分类与分布
根据《中国植物志》(第七卷),现存裸子植物 分为4纲,9目,12科,71属,约800种。我国是 裸子植物资源丰富、种类众多的国家,有4纲,8 目,11科,41属,约240种,其中有许多种类是 中国特有植物或世界闻名的“活化石”植物,如 银杏、银杉、金钱松、水杉、水松等。
从发生到现在,地史气候发生多次重大变化,裸 子植物也随之多次演变更替,老的种类不断灭绝,新 的种类不断产生,种类演替繁衍至今。
裸子植物的主要特征(区别于被子植物)
1. 全为木本植物,孢子体发达,多为乔木;木 质部以管胞为主,稀具导管; 2. 配子体退化,多数植物雌配子体具颈卵器; 3. 孢子叶聚集成孢子叶球(球花),单性;没 有真正的花; 4. 产生种子,种子裸露,不形成果实。
裸子植物常见形态术语介绍,另讲
一、苏铁纲(Cycadosida)
起源于古生代石炭纪,繁盛于中生代侏罗纪、白 垩纪(是恐龙当时重要的食物)。
现存2科,分布于热带、亚热带地区,中国仅苏 铁科(Cycadaceae)一科。
苏铁科 Cycadaceae 主要特征:
常绿木本植物 ,茎粗壮,髓部发达,常不分枝; 叶革质,大型,羽状深裂,簇生枝顶; 雌雄异株,球花(孢子叶球)单生于茎顶; 雄球花柱状,生多数小孢子囊(花药); 雌球花球状或柱状,羽状分裂,边沿着生2-10个胚珠; 种子核果状,种皮3层。
3. 药用树种:裸子植物中具有药用价值的种类极多。如铁树、 银杏、侧柏等的叶和种子;油松、马尾松等的针叶和花粉;三 尖杉、红豆杉、麻黄等可提取生物碱。
新编英语教程6,单词
4.PHRASAL VERB短语动词完满解答,妥善解决(问题等) If youtie upan issue or problem, you deal with it in a way that gives definite conclusions or answers.
Diglossia/ dai5^lCsiE;NAmE-5^lC:s-; -5^lB:s- /noun [U]•di·glos·sicadj.
(linguistics语言)a situation in which ten languages or ten forms of a language are used under different conditions in a community双语现象,双变体现象(两种语言或一种语言的两种变体并存于一个语言集体中)
jargonUK['dʒɑ:.gən]US['dʒɑ:r-] usuallydisapproving
noununcountable■special words and phrases which are used by particular groups ofpeople, especially in their work行话,行业术语
■the scientific study of the body and how its parts are arranged解剖(学)countable or uncountable
■the structure of an animal or plant解剖构造;(动植物)结构
■a person's body身体
第二类精神药品处方点评范文
第二类精神药品处方点评范文英文回答:Prescription drugs are classified into different categories based on their therapeutic uses and potentialfor abuse. The second class of prescription drugs includes psychotropic medications, which are primarily used to treat mental health disorders. These drugs can have a significant impact on a person's mood, cognition, and behavior. In this essay, I will discuss the various aspects of second-class psychotropic medications and provide examples to illustrate their effects.First and foremost, it is important to understand that psychotropic medications are prescribed by healthcare professionals to alleviate symptoms associated with mental health conditions. For instance, antidepressants are commonly prescribed to individuals suffering from depression. These medications work by balancing the chemicals in the brain, such as serotonin, to improve moodand reduce feelings of sadness or hopelessness. One example of an antidepressant is Prozac, which has been widely used and proven effective in treating depression.In addition to antidepressants, antipsychotic medications are another type of psychotropic drug commonly prescribed. These medications are primarily used to manage symptoms of psychosis, such as hallucinations or delusions. One well-known antipsychotic medication is Risperdal, which is often prescribed to individuals with schizophrenia. Risperdal helps reduce the severity of psychotic symptoms and allows individuals to better function in their daily lives.Moreover, psychotropic medications also include mood stabilizers, which are used to manage mood swings and prevent episodes of mania or depression in individuals with bipolar disorder. Lithium is a commonly prescribed mood stabilizer that has been shown to effectively regulate mood and reduce the frequency and intensity of mood swings. Individuals taking lithium often report feeling more stable and in control of their emotions.Furthermore, it is important to note that while psychotropic medications can be highly beneficial in managing mental health conditions, they also come with potential side effects. These side effects can vary depending on the specific medication and individual factors. For example, common side effects of antidepressants may include nausea, drowsiness, or sexual dysfunction. It is crucial for individuals taking psychotropic medications to closely monitor their symptoms and communicate any concerns with their healthcare provider.In conclusion, second-class psychotropic medications play a crucial role in the treatment of mental health disorders. They can effectively alleviate symptoms and improve the overall well-being of individuals withconditions such as depression, schizophrenia, and bipolar disorder. However, it is important to carefully considerthe potential side effects and work closely with healthcare professionals to find the most suitable medication and dosage. By doing so, individuals can achieve better mental health and lead fulfilling lives.中文回答:精神药物根据其治疗用途和滥用潜力被划分为不同的类别。
发展心理学专业术语表
发展心理学专业术语表acceleration 加速accommodation 顺应acquired immune deficiency syndrome (AIDS) 获得性免疫缺陷综合征active engagement 积极参与acute medical conditions 急性疾病adaptation 适应adolescence 青少年期adolescent growth spurt 青春期发育突进adolescent rebellion 青春期叛逆affordances 可用性alleles 等位基因altruism 利他主义ambivalent (resistant) attachment 矛盾型(抗拒型)依恋animism 泛灵论anorexia nervosa 神经性厌食症anoxia 缺氧症Apgar scale 阿普加量表art therapy 艺术疗法assimilation 同化asthma 哮喘attachment 依恋attention-deficit/hyperactivity disorder 注意力缺陷/多动症authoritarian 专制型authoritative 权威型autism 自闭症autobiographical memory 自传体记忆autonomy versus shame and doubt 自主对羞愧和怀疑autosomes 常染色体avoidant attachment 回避型依恋basic trust versus basic mistrust 基本信任对基本不信任Bayley Scales of Ifant Development 贝雷婴儿发展量表behavior therapy 行为治疗behavioral genetic 行为遗传学behaviorism 行为主义behaviorist approach 行为主义的方法bilingual 双语使用者bilingual education 双语教学bioecological theory 生态学理论birth trauma 产伤body image 身体意象brain growth spurts 脑的发育加速期Brazelton Neonatal Behavioral Assessment Scales 布氏新生儿行为评价量表bulimia nervosa 神经性贪食症bullying 欺负canalization 定型化case study 个案研究cell death 细胞死亡central executive 中央执行central nervous system 中枢神经系统centration 中心化cephalocaudal principle 头尾原则cesarean delivery 剖腹产child-directed speech (CDS) 儿语化childhood depression 儿童郁抑症chromosomes 染色体chronic medical conditions 慢性疾病chronosystem 时序系统circular reaction 循环反应class inclusion类包含classical conditioning 经典条件作用code mixing 语码混用code switching 语码转换cognitive development 认知发展cognitive neuroscience approach 认知神经科学的方法cognitive neuroscience 认知神经科学cognitive perspective 认知理论cognitive-stage theory 认知发展阶段理论cohort 同辈commitment 承诺committed compliance 约束性顺从componential element 成分元素conceptual knowledge 概念性知识concordant 一致concrete operations 具体运算conduct disorder (CD) 品行障碍conscience 良心conservation 守恒constructive play 建构性游戏contextual element 情境元素contextual perspective 情境理论control group 控制组conventional morality (or morality of conventional role conformity) 习俗道德convergent thinking 聚合思维coregulation共同约束corporal punishment 体罚correlational study 相关研究creativity 创造力crisis危机critical period 关键期cross-modal transfer 跨通道迁移cross-sectional study 横断研究cultural bias 文化偏见culture文化culture-fair 文化公平culture-free 不受文化影响culture-relevant 文化相关decenter 去中心化declarative knowledge 陈述性知识decoding 解码deductive reasoning 演绎推理deferred imitation 延迟模仿Denver Developmental Screening Test 丹佛发展筛选测验deoxyribonucleic acid (DNA) 脱氧核糖核酸dependent variable 因变量depth perception 深度知觉differentiation 分化“difficult”children “困难型”儿童discipline 训练dishabituation 去习惯化disorganized-disoriented attachment 无组织-无目标依恋divergent thinking 发散思维dizygotic twins 双卵性双胞胎dominant inheritance 显性遗传Down syndrome 唐氏综合征drug therapy 药物治疗dual representation hypothesis 双重表征理论dyslexia 难语症early intervention 早期干预“easy”children “容易型”儿童ecological theory of perception 生态知觉理论egocentrism 自我中心主义elaboration 精细加工electronic fetal monitoring 胎心电子监护elicited imitation 诱导模仿embryonic stage 胚胎期emergent literacy 早期读写能力emotional maltreatment 情感虐待emotions 情绪empathy 同理心encoding 编码English-immersion 全英语教学enrichment 充实enuresis 尿床environment 环境episodic memory 情景记忆equilibration平衡ethnic gloss 种族曲解ethnographic study 人种志研究ethology 习性学evolutionary psychology 进化心理学evolutionary/sociobiological perception 进化论/社会生物学理论exosystem 在外系统experiential element 经验元素experiment 实验experiental group 实验组explicit memory 外显记忆extended family 大家庭external memory aids 外部记忆辅助手段family therapy 家庭治疗fast mapping 快速映射fertilization 受精fetal alcohol syndrome(FAS)胎儿酒精综合症fetal stage 胎儿期fine motor skills 精细动作技能foreclosure 同一性早闭formal operations 形式运算functional play 功能性游戏gateway drugs 入门毒品gender 性别gender constancy 性别恒常性gender identity 性别认同gender roles 性别角色gender stereotypes 性别刻板影响gender-schema theory 性别-图式理论gender-typing 性别原型generalized anxiety disorder 一般性焦虑障碍generic memory 通用记忆genes 基因genetic code 遗传密码genetic counseling 基因咨询genotype 基因型genotype-environment correlation 基因型-环境相关genotype-environment interaction 基因型-环境交互作用germinal stage 胚芽期goodness of fit 吻合度gross motor skills 粗略动作技能guided participation 引导性参与habituation 习惯化handedness 利手haptic perception 触觉感知heredity 遗传heritability 遗传力heterozygous 杂合的historical generation 特定历史时代的人holophrase 单词句Home Observation for Measurement of the Environment 家庭环境观察测评系统homozygous 纯合的horizontal decalage 水平滞差hostile aggressive 敌意性攻击human development 发展心理学hypertension 高血压hypotheses 假设hypothetical-deductive reasoning 假设-演绎推理ideal self 理想自我identification 认同identity 同一性identity achievement 同一性获得identity diffusion 同一性扩散identity statuses 同一性状态identity versus identity confusion 同一性对同一性混乱imaginary audience 假象观众implicit memory 内隐记忆imprinting 印刻incomplete dominance 不完全显性independent variable 自变量individual differences 个体差异individual psychotherapy个别心理治疗inductive reasoning 归纳推理inductive techniques 诱导技术industry versus inferiority 勤奋对自卑infant mortality rate 婴儿死亡率information-processing approach 信息加工取向initiative versus guilt 主动对内疚instrumental aggression 工具性攻击integration 整合intelligent behavior 智力行为internalization 内化invisible imitation 不可见模仿IQ(intelligence quotient)tests 智商测验irreversibility 不可逆性Kaufman Assessment Battery for Children 考夫曼儿童成套评估测验laboratory Observation 实验室观察language 语言language acquisition device(LAD) 语言习得机制lateralization 单侧化优势learning perspective 学习理论life-span development 毕生发展linguistic speech 语言式讲话literacy 读写能力longitudinal study 纵向研究long-term memory 长时记忆low birth weight 低体重儿macrosystem 宏观系统maturation 成熟mechanistic model 机械论发展模型menarche 月经初期mental retardation 精神发育迟滞mesosystem 中观系统metamemory 元记忆microsystem 微观系统monozygotic twins 单卵性双胞胎moratorium 同一性延缓multifactorial transmission 多因素传递mutations 突变mutual regulation 相互调节myelination 髓鞘化nativism 先天论natural childbirth 自然分娩naturalistic observation 自然观察neglect 忽视neonatal jaundice 新生儿黄疸neonatal period 新生儿期neonate 新生儿neurons 神经元niche-picking 匹配选择nonnormative 非常态的nonshared environmental effects 非共享环境影响normative 常态的nuclear family 核心家庭obesity 肥胖object permanence 客体永久性observational learning 观察学习obsessive-compulsive disorder (OCD) 强迫症open adoption 公开领养operant conditioning 操作性条件作用operational definition 操作定义oppositional defiant disorder (ODD) 对立违抗性障碍organismic model 有机论发展模型organization 组织Otis-Lennon School Ability Test 欧提斯-列农学业能力测试overt aggression 外显攻击participant observation 参与观察parturition 分娩permissive 放任型personal fable 个人神话phenotype 表现型phonetic, or code-emphasis approach 语音或编码强调法physical abuse 身体虐待physical development 生理发展Piagetian approach 皮亚杰理论的方法plasticity 可塑性play therapy 游戏疗法polygenic inheritance 多基因遗传postconvertional morality (or morality of autonomous moral principles)后习俗道德postmature 胎儿过度成熟power assertion 强制命令pragmatics 语用学preconventional morality 前习俗道德prejudice 偏见prelinguistic speech 前语言式讲话preoperational stage 前运算阶段prepared childbirth 有准备的分娩pretend play 假装游戏preterm (premature)infants 早产儿primary sex characteristics 第一性征private speech 自言自语procedural knowledge 程序性知识prosocial behavior 亲社会行为protective factors 保护因素proximodistal principle 远近原则psychoanalytic perspective 精神分析理论psychological aggression 心理攻击psychometric approach 心理测量的方法psychosexual development 性心理发展psychosocial development 心理社会发展puberty 青春期punishment 惩罚qualitative change 质变qualitative research 定性研究quantitative change 量变quantitative research 定量研究reaction range 反应范围real self 真实自我recall 回忆recessive inheritance 隐性遗传recognition 再认reflex behaviors 反射行为rehearsal 复述reinforcement 强化relational aggression 关系攻击representational ability 表征能力representational mappings 表征映射representational systems 表征系统resilient children 韧性儿童retrieval 提取risk factors 风险因素rough-and-tumble play 追逐打闹游戏sample 样本scaffolding 脚手架schemes 图式schizophrenia 精神分裂症school phobia 学校恐惧症scientific method 科学方法script 脚本secondary sex characteristics 第二性征secular trend 长势趋势secure attachment 安全依恋型self-awareness 自我意识self-conscious emotions 自我意识情绪self-definition 自我定义self-efficacy 自我效能感self-esteem 自尊self-evaluative emotions 自我评价情绪self-regulation 自我调节sensitive periods 敏感期sensorimotor stage 感知运动阶段sensory memory 感觉记忆separation anxiety 分离焦虑separation anxiety disorder 分离焦虑障碍sequential study 序列研究seriation 排序sex chromosomes 性染色体sex-linked-inheritance 伴性遗传sexual abuse 性虐待sexual orientation 性取向sexually transmitted diseases(STDs) 性传播疾病single representations 单一表征situational compliance 情境性顺从“slow-to-warm-up”children “慢热型”儿童small-for-date(small-for-gestational age) infants 小于胎龄儿social capital 社会资本social cognition 社会认知social cognitive theory 社会认知理论social construction 社会建构social interaction model 社会互动模型social learning theory 社会学习理论social phobia 社交恐惧症social promotion 社会促动social referencing 社会参照social-contextual approach 社会情境的方法socialization 社会化sociocultural theory 社会文化理论socioeconomic status(SES) 社会经济地位spermarche 初精spontaneous abortion 自发性流产Stanford-Binet Intelligence Scale 斯坦福-比奈智力量表state of arousal 觉醒状态Sternberg Triarchic Abilities Test (STAT)斯滕伯格三元能力测验“still-face”paradigm “冷面”范式storage 存储Strange Situation 陌生情境stranger anxiety 陌生人焦虑substance abuse 物质滥用substance dependence 物质依赖sudden infant death syndrome(SIDS)胎儿猝死综合症symbolic function 符号功能syntax 语法systems of action 动作系统tacit knowledge 内隐知识telegraphic speech 电报句temperament 气质teratogenic 致畸的theory 理论theoryof mind 心理理论theory of multiple intelligences 多元智力理论transduction 转换transitive inference 传递性关系推理triarchic theory of intelligence 智力三元理论two-way(dual-language)learning 双向学习ultrasound 超声波violation-of-expectations 期望悖反的范式visible imitation 可见的模仿visual cliff 视崖visual guidance 视觉引导visual preference 视觉偏好visual recognition memory 视觉认知记忆visually based retrieval 基于视觉的提取Wechsler Intelligence Scale for Children(WISC-Ⅲ)韦氏儿童智力量表Wechsler Preschool and Primary Scale of Intelligence,Revised(WPPSI-Ⅲ)修订版韦克奇勒学前和小学智力量表whole-language approach 全语言教学法withdrawal of love 收回爱working memory 工作记忆zone of proximal development (ZPD) 最近发展区zygote 受精卵。
心境障碍(英文)
Epidemiology
Symptoms and disorders of the depression spectrum are rather common. Lifetime prevalence rates for depressive symptoms are 13%~20% and for major depressive disorder 3.7%~6.7% . Major depressive disorder is about two to three times as common in adolescent and adult females as in adolescent and adult males. In prepubertal children, boys and girls are affected equally. Rates in women and men are highest in the 25-to44-year-old age group.
The episode Severity Type Special features Mild, moderate, or severe Depressive, manic, mixed With melancholic symptoms With neurotic symptoms With psychotic symptoms With agitation With retardation or stupor Unipolar or bipolar Predominantly reactive Predominantly endogenous
1981年克朗奎斯特被子植物分类系统
/1981年克朗奎斯特被子植物分类系统诸葛按:本分类系统大纲载于An Integrated System of Classification of Flowering Plants, Columbia University Press, 1981一书中。
各分类单位的中文译名中,除了约定俗成的科名和由科名类推得到的高级分类单位名称外,非国产科的中文译名主要来自汤彦承、路安民《被子植物非国产科汉名的初步拟订》,植物分类学报,41(3):285-304(2003)一文。
点击链接可以查看同书中对该类群的介绍。
OUTLINE OF CLASSIFICATION OF MAGNOLIOPHYTA木兰植物门分类大纲Class MAGNOLIOPSIDA木兰纲Subclass I. Magnoliidae木兰亚纲Order 1. Magnoliales木兰目Family 1. Winteraceae林仙科2. Degeneriaceae单心木兰科3. Himantandraceae瓣蕊花科4. Eupomatiaceae帽花木科5. Austrobaileyaceae木兰藤科6. Magnoliaceae木兰科7. Lactoridaceae囊粉花科8. Annonaceae番荔枝科9. Myristacaceae肉豆蔻科10. Canellaceae白樟科Order 2. Laurales樟目Family 1. Amborellaceae无油樟科2. Trimeniaceae早落瓣科3. Monimiaceae杯轴花科4. Gomortegaceae葵乐果科5. Calycanthaceae蜡梅科6. Idiospermaceae奇子树科7. Lauraceae樟科8. Hernandiaceae莲叶桐科Order 3. Piperales胡椒目Family 1. Cloranthaceae金粟兰科2. Saururaceae三白草科3. Piperaceae胡椒科Order 4. Aristolochiales马兜铃目Family 1. Aristolochiaceae马兜铃科Order 5. Illiciales八角目Family 1. Illiciaceae八角科2. Schisandraceae五味子科Order 6. Nymphaeales睡莲目Family 1. Nelumbonaceae莲科2. Nymphaeaceae睡莲科3. Barclayaceae合瓣莲科4. Cabombaceae莼菜科5. Ceratophyllaceae金鱼藻科Order 7. Ranunculales毛茛目Family 1. Ranunculaceae毛茛科2. Circaeasteraceae星叶草科3. Berberidaceae小檗科4. Sargentodoxaceae大血藤科5. Lardizabalaceae木通科6. Menispermaceae防己科7. Coriariaceae马桑科8. Sabiaceae清风藤科Order 8. Papaverales罂粟目Family 1. Papaveraceae罂粟科2. Fumariaceae紫堇科Subclass II. Hamamelidae金缕梅亚纲Order 1. Trochodendrales昆栏树目Family 1. Tetracentraceae水青树科2. Trochodendraceae昆栏树科Order 2. Hamamelidales金缕梅亚纲Family 1. Cercidiphyllaceae连香树科2. Eupteliaceae领春木科3. Platanaceae悬铃木科4. Hamamelidaceae金缕梅科5. Myrothamnaceae折扇叶科Order 3. Daphniphyllales交让木目Family 1. Daphniphyllaceae交让木科Order 4. Didymelales双蕊花目Family 1. Didymelaceae双蕊花科Order 5. Eucommiales杜仲目Family 1. Eucommiaceae杜仲科Order 6. Urticales荨麻目Family 1. Barbeyaceae钩毛叶科2. Ulmaceae榆科3. Cannabaceae大麻科4. Moraceae桑科5. Cecropiaceae伞树科6. Urticaceae荨麻科Order 7. Leitneriales塞子木目Family 1. Leitneriaceae塞子木科Order 8. Juglandales胡桃目Family 1. Rhoipteleaceae马尾树科2. Juglandaceae胡桃科Order 9. Myricales杨梅目Family 1. Myricaceae杨梅科Order 10. Fagales壳斗目Family 1. Balanopaceae橡子木科2. Fagaceae壳斗科3. Betulaceae桦木科Order 11. Casuarinales木麻黄目Family 1. Casuarinaceae木麻黄科Subclass III. Caryophyllidae石竹亚纲Order 1. Caryophyllales石竹目Family 1. Phytolaccaceae商陆科2. Achatocarpaceae玛瑙果科3. Nyctaginaceae紫茉莉科4. Aizoaceae番杏科5. Didiereaceae刺戟草科6. Cactaceae仙人掌科7. Chenopodiaceae藜科8. Amaranthaceae苋科9. Portulacaceae马齿苋科10. Basellaceae落葵科11. Molluginaceae粟米草科12. Caryophyllaceae石竹科Order 2. Polygonales蓼目Family 1. Polygonaceae蓼科Order 3. Plumbaginales白花丹目Family 1. Plumbaginaceae白花丹科Subclass IV. Dilleniidae五桠果亚纲Order 1. Dilleniales五桠果目Family 1. Dilleniaceae五桠果科2. Paeoniaceae芍药科Order 2. Theales山茶目Family 1. Ochnaceae金莲木科2. Sphaerosepalaceae球萼树科3. Sarcolaenaceae苞杯花科4. Dipterocarpaceae龙脑香科5. Caryocaraceae油桃木科6. Theaceae山茶科7. Actinidiaceae猕猴桃科8. Scytopetalaceae革瓣花科9. Pentaphylacaceae五列木科10. Tetrameristaceae四出花科11. Pellicieraceae假红树科12. Oncothecaceae钩药茶科13. Marcgraviaceae蜜囊花科14. Quiinaceae绒子树科15. Elatinaceae沟繁缕科16. Paracryphiaceae盔瓣花科17. Medusagynaceae伞果树科18. Clusiaceae藤黄科Order 3. Malvales锦葵目Family 1. Elaeocarpaceae杜英科2. Tiliaceae椴树科3. Sterculiaceae梧桐科4. Bombacaceae木棉科5. Malvaceae锦葵科Order 4. Lecythidales玉蕊目Family 1. Lecythidaceae玉蕊科Order 5. Nepenthales猪笼草目Family 1. Sarraceniaceae瓶子草科2. Nepenthaceae猪笼草科3. Droseraceae茅膏菜科Order 6. Violales堇菜目Family 1. Flacourtiaceae刺篱木科2. Peridiscaceae围盘树科3. Bixaceae红木科4. Cistaceae半日花科5. Huaceae蒜树科6. Lacistemataceae裂药花科7. Scyphostegiaceae杯盖花科8. Stachyuraceae旌节花科9. Violaceae堇菜科10. Tamaricaceae柽柳科11. Frankeniaceae瓣鳞花科12. Dioncophyllaceae双钩叶科13. Ancistrocladaceae钩枝藤科14. Turneraceae时钟花科15. Malesherbiaceae王冠草科16. Passifloraceae西番莲科17. Achariaceae脊脐子科18. Caricaceae番木瓜科19. Fouquieriaceae澳可第罗科20. Hoplestigmataceae干戈柱科21. Cucurbitaceae葫芦科22. Datiscaceae四数木科23. Begoniaceae秋海棠科24. Loasaceae刺莲花科Order 7. Salicales杨柳目Family 1. Salicaceae杨柳科Order 8. Capparales白花菜目Family 1. Tovariaceae鲜芹味科2. Capparaceae白花菜科3. Brassicaceae十字花科4. Moringaceae辣木科5. Resedaceae木犀草科Order 9. Batales肉穗果目Family 1. Gyrostemonaceae环蕊木科2. Bataceae肉穗果科Order 10. Ericales杜鹃花目Family 1. Cyrillaceae翅萼树科2. Clethraceae桤叶树科3. Grubbiaceae毛盘花科4. Empetraceae岩高兰科5. Epacridaceae澳石南科6. Ericaceae杜鹃花科7. Pyrolaceae鹿蹄草科8. Monotropaceae水晶兰科Order 11. Diapensiales岩梅目Family 1. Diapensiaceae岩梅科Order 12. Ebenales柿树目Family 1. Sapotaceae山榄科2. Ebenaceae柿树科3. Styracaceae安息香科4. Lissocarpaceae光果科5. Symplocaceae山矾科Order 13. Primulales报春花目Family 1. Theophrastaceae拟棕科2. Myrsinaceae紫金牛科3. Primulaceae报春花科Subclass V. Rosidae蔷薇亚纲Order 1. Rosales蔷薇目Family 1. Brunelliaceae槽柱花科2. Connaraceae牛栓藤科3. Eucryphiaceae落帽花科4. Cunoniaceae南蔷薇科5. Davidsoniaceae大维逊李科6. Dialypetalanthaceae拟素馨科7. Pittosporaceae海桐花科8. Byblidaceae二型腺毛科9. Hydrangeaceae八仙花科10. Columelliaceae弯药树科11. Grossulariaceae茶藨子科12. Greyiaceae鞘叶树科13. Bruniaceae鳞叶树科14. Anisophylleaceae异叶木科15. Alseuosmiaceae假海桐科16. Crassulaceae景天科17. Cephalotaceae囊叶草科18. Saxifragaceae虎耳草科19. Rosaceae蔷薇科20. Neuradaceae两极孔草科21. Crossosomataceae流苏子科22. Chrysobalanaceae可可李科23. Surianaceae海人树科24. Rhabdodendraceae棒状木科Order 2. Fabales豆目Family 1. Mimosaceae含羞草科2. Caesalpiniaceae云实科3. Fabaceae豆科Order 3. Proteales山龙眼目Family 1. Elaeagnaceae胡颓子科2. Proteaceae山龙眼科Order 4. Podostemales川薹草目Family 1. Podostemaceae川薹草科Order 5. Haloragales小二仙草目Family 1. Haloragaceae小二仙草科2. Gunneraceae大叶草科Order 6. Myrtales桃金娘目Family 1. Sonneratiaceae海桑科2. Lythraceae千屈菜科3. Penaeaceae管萼木科4. Crypteroniaceae隐翼科5. Thymelaeaceae瑞香科6. Trapaceae菱科7. Myrtaceae桃金娘科8. Punicaceae石榴科9. Onagraceae柳叶菜科10. Oliniaceae方枝树科11. Melastomataceae野牡丹科12. Combretaceae使君子科Order 7. Rhizophorales红树目Family 1. Rhizophoraceae红树科Order 8. Cornales山茱萸目Family 1. Alangiaceae八角枫科2. Nyssaceae蓝果树科3. Cornaceae山茱萸科4. Garryaceae丝缨花科Order 9. Santalales檀香目Family 1. Meduandraceae毛丝花科2. Dipentodontaceae十齿花科3. Olacaceae铁青树科4. Opiliaceae山柚子科5. Santalaceae檀香科6. Misodendraceae羽果科7. Loranthaceae桑寄生科8. Viscaceae槲寄生科9. Eremolepidaceae绿乳科10. Balanophoraceae蛇菰科Order 10. Rafflesiales大花草目Family 1. Hydnoraceae腐臭草科2. Mitrastemonaceae帽蕊草科3. Rafflesiaceae大花草科Order 11. Celastrales卫矛目Family 1. Geissolomataceae四棱果科2. Celastraceae卫矛科3. Hippocrateaceae翅子藤科4. Stackhousiaceae异雄蕊科5. Salvadoraceae刺茉莉科6. Aquifoliaceae冬青科7. Icacinaceae茶茱萸科8. Aextoxicaceae毒羊树科9. Cardiopteridaceae心翼果科10. Corynocarpaceae棒果木科11. Dichapetalaceae毒鼠子科Order 12. Euphorbiales大戟目Family 1. Buxaceae黄杨科2. Simmondsiaceae油蜡树科3. Pandaceae攀打科4. Euphorbiaceae大戟科Order 13. Rhamnales鼠李目Family 1. Rhamnaceae鼠李科2. Leeaceae火筒树科3. Vitaceae葡萄科Order 14. Linales亚麻目Family 1. Erythroxylaceae古柯科2. Humiriaceae树脂核科3. Ixonanthaceae粘木科4. Hugoniaceae亚麻藤科5. Linaceae亚麻科Order 15. Polygalales远志目Family 1. Malpighiaceae金虎尾科3. Trigoniaceae三角果科4. Tremandraceae孔药木科5. Polygalaceae远志科6. Xanthophyllaceae黄叶树科7. Krameriaceae刺球果科Order 16. Sapindales无患子目Family 1. Stapyleaceae省沽油科2. Melianthaceae蜜花科3. Bretschneideraceae钟萼木科4. Akaniaceae叠珠树科5. Sapindaceae无患子科6. Hippocastanaceae七叶树科7. Aceraceae槭树科8. Burseraceae橄榄科9. Anacardiaceae漆树科10. Julianiaceae三柱草科11. Simaroubaceae苦木科12. Cneoraceae叶柄花科13. Meliaceae楝科14. Rutaceae芸香科15. Zygophyllaceae蒺藜科Order 17. Geraniales牻牛儿苗目Family 1. Oxalidaceae酢浆草科2. Geraniaceae牻牛儿苗科3. Limnanthaceae沼花科4. Tropaeolaceae旱金莲科5. Balsaminaceae凤仙花科Order 18. Apiales伞形目Family 1. Araliaceae五加科2. Apiaceae伞形科Subclass VI. Asteridae菊亚纲Order 1. Gentianales龙胆目Family 1. Loganiaceae马钱科2. Retziaceae异轮叶科3. Gentianaceae龙胆科4. Saccifoliaceae勺叶木科5. Apocynaceae夹竹桃科6. Asclepiadaceae萝藦科Order 2. Solanales茄目Family 1. Duckeodendraceae核果茄科2. Nolanaceae假茄科3. Solanaceae茄科5. Cuscutaceae菟丝子科6. Menyanthaceae睡菜科7. Polemoniaceae花荵科8. Hydrophyllaceae田基麻科Order 3. Lamiales唇形目Family 1. Lennoaceae多室花科2. Boraginaceae紫草科3. Verbenaceae马鞭草科4. Lamiaceae唇形科Order 4. Callitrichales水马齿目Family 1. Hippuridaceae杉叶藻科2. Callitrichaceae水马齿科3. Hydrostachyaceae水穗草科Order 5. Plantaginales车前目Family 1. Plantaginaceae车前科Order 6. Scrophulariales玄参目Family 1. Buddlejaceae醉鱼草科2. Oleaceae木犀科3. Scrophulariaceae玄参科4. Globulariaceae肾药花科5. Myoporaceae苦槛蓝科6. Orobanchaceae列当科7. Gesneriaceae苦苣苔科8. Acanthaceae爵床科9. Pedaliaceae胡麻科10. Bignoniaceae紫葳科11. Mendonciaceae对叶藤科12. Lentibulariaceae狸藻科Order 7. Campanulales桔梗目Family 1. Pentaphragmataceae五膜草科2. Sphenocleaceae楔瓣花科3. Campanulaceae桔梗科4. Stylidiaceae花柱草科5. Donatiaceae陀螺果科6. Brunoniaceae蓝针花科7. Goodeniaceae草海桐科Order 8. Rubiales茜草目Family 1. Rubiaceae茜草科2. Theligonaceae假牛繁缕科Order 9. Dipsacales川续断目Family 1. Caprifoliaceae忍冬科2. Adoxaceae五福花科3. Valerianaceae败酱科Order 10. Calycerales萼角花目Family 1. Calyceraceae萼角花科Order 11. Asterales菊目Family 1. Asteraceae菊科Class LILIOPSIDA百合纲Subclass I. Alismatidae泽泻亚纲Order 1. Alismatales泽泻目Family 1. Butomaceae花蔺科2. Limnocharitaceae黄花蔺科3. Alismataceae泽泻科Order 2. Hydrocharitales水鳖目Family 1. Hydrocharitaceae水鳖科Order 3. Najadales茨藻目Family 1. Aponogetonaceae水蕹科2. Scheuchzeriaceae冰沼草科3. Juncaginaceae水麦冬科4. Potamogetonaceae眼子菜科5. Ruppiaceae川蔓藻科6. Najadaceae茨藻科7. Zannichelliaceae角果藻科8. Posidoniaceae波喜荡科9. Cymodoceaceae丝粉藻科10. Zosteraceae大叶藻科Order 4. Triuridales霉草目Family 1. Petrosaviaceae无叶莲科2. Triuridaceae霉草科Subclass II. Arecidae槟榔亚纲Order 1. Arecales槟榔目Family 1. Arecaceae槟榔科Order 2. Cyclanthales巴拿马草目Family 1. Cyclanthaceae巴拿马草科Order 3. Pandanales露兜树目Family 1. Pandanaceae露兜树科Order 4. Arales天南星目Family 1. Araceae天南星科2. Lemnaceae浮萍科Subclass III. Commelinidae鸭跖草亚纲Order 1. Commelinales鸭跖草目Family 1. Rapateaceae瑞碑题雅科2. Xyridaceae黄眼草科3. Mayacaceae花水藓科4. Commelinaceae鸭跖草科Order 2. Eriocaulales谷精草目Family 1. Eriocaulaceae谷精草科Order 3. Restionales帚灯草目Family 1. Flagellariaceae须叶藤科2. Joinvilleaceae拟苇科3. Restionaceae帚灯草科4. Centrolepidaceae刺鳞草科Order 4. Juncales灯心草目Family 1. Juncaceae灯心草科2. Thurniaceae梭子草科Order 5. Cyperales莎草目Family 1. Cyperaceae莎草科2. Poaceae禾本科Order 6. Hydatellales独蕊草目Family 1. Hydatellaceae独蕊草科Order 7. Typhales香蒲目Family 1. Sparganiaceae黑三棱科2. Typhaceae香蒲科Subclass IV. Zingiberidae姜亚纲Order 1. Bromeliales凤梨目Family 1. Bromeliaceae凤梨科Order 2. Zingiberales姜目Family 1. Streliziaceae鹤望兰科2. Heliconiaceae蝎尾蕉科3. Musaceae芭蕉科4. Lowiaceae兰花蕉科5. Zingiberaceae姜科6. Costaceae闭鞘姜科7. Cannaceae美人蕉科8. Marantaceae竹芋科Subclass V. Liliidae百合亚纲Order 1. Liliales百合目Family 1. Philydraceae田葱科2. Pontederiaceae雨久花科3. Haemodoraceae血草科4. Cyanastraceae蓝星科5. Liliaceae百合科6. Iridaceae鸢尾科7. Velloziaceae翡若翠科8. Aloeaceae芦荟科9. Agavaceae龙舌兰科10. Xanthorrhoeaceae黄脂木科11. Hanguanaceae钵子草科12. Taccaceae蒟蒻薯科13. Stemonaceae百部科14. Smilacaceae菝葜科15. Dioscoreaceae薯蓣科Order 2. Orchidales兰目Family 1. Geosiridaceae地鸢尾科2. Burmanniaceae水玉簪科3. Corsiaceae腐蛛草科4. Orchidaceae兰科木兰植物门(MAGNOLIOPHYTA)Cronquist, Takhtajan & Zimmermann 1966又名被子植物或有花植物维管束植物,一般具有根、茎和叶,茎的中央柱(central cylinder)有叶隙或分散的维管束;木质部通常(但并非总是)含有导管的一部分,至少在根部如此;韧皮部有定数的筛管和伴胞。
心理学专业词汇英语翻译R
R 反应R class 反应类R correlation R相关R factor 推理因素R method R法R variable 反应变量rabbit 兔子rabies 狂犬病race 种族race attitude 种族态度race difference 种族差异race discrimination 种族歧视race diversity 种族差异性race prejudice 种族偏见race psychology 种族心理学race relation 种族关系racial difference 种族差别racial discrimination 种族歧视racial diversity 种族差异性racial identity 种族认同racial inheritance 种族遗传racial memory 种族记忆racial mixture 种族混合racial prejudice 种族偏见racial unconscious 种族潜意识racialism 种族主义racialist 种族主义者racism 种族歧视radar 雷达radial 半径radial method of rotation 半径轴转法radiance 光亮度radiant emittance 辐射发散度radiant flux 辐射束radiant heat method 热传导法radiant intensity 辐射强度radiant reflectance 辐射反射率radiantive heat transfer coefficient 辐射热传递系数radiate 辐射radiation 放射radiation genetics 放射遗传学radiation therapy 放射疗法radiation induced aberration 辐射诱导畸变radical behaviorism 激进行为主义radical idea 激进思想radical therapy 彻底治疗法radicalism 激进主义radio advertising 广播广告radioaction 放射性反应radioactive substance 放射物质radiobiology 放射生物学radiocardiogram 放射心电图radiocardiography 放射心电描记法radioelectrocardiogram 放射心电图radioelectrocardiograph 放射心电描记法放射心电描记法radioelectronics 无线电电子学radioelement 放射性元素radioencephalogram 放射脑电图radioencephalography 放射脑电描记法放射脑电描记法radiogenetics 辐射遗传学radioisotope 放射性同位素radiology 放射学radiolucent 射线可透过的radioman 无线电技师radiometer 辐射仪radiophobia 射线恐怖症radiophysics 放射物理学radiophysiology 放射生理学radioreaction 放射反应radioreceptor 放射性受体radiosensitive 对辐射敏感的radiosensitivity 辐射敏感性radiostimulation 辐射刺激作用radiosusceptibility 辐射易感性radiotherapeutics 放射疗法radiotherapy 放射疗法radiothermy 热放射疗法radium 镭radium therapy 放射疗法radius 半径rage 愤怒Ragoni Scina contrast 拉高尼 西纳方形对比railroad nystagmus 铁道性眼振railroadphobia 恐火车症railway illusion 铁路错觉Raleigh equation 拉雷方程Raman shift 瑞曼移动rament 气质激素说rami cardiaci 迷走神经心支rami gastrici 迷走神经胃支ramification 分枝random 随机random access 随机存取random answer 随机回答random assignment 随机分派random assortment 随机分类random behavior 随机行为random case 随机情况random cause 随机原因random character 随机特征random choice 随机选择random difference 随机差random digit dialing 随机数字拨号random distribution 随机分布random disturbance 随机扰动random dot stereogram 随机点实体图random effect 随机效果random effect model 随机效果模式random enquire 随机询问random error 随机误差random event 随机事件random experiment 随机试验random factor 随机因素random fluctuation 随机变动random genetic drift 随机遗传漂变random group 随机组random group design 随机组设计random learning 随机学习random manner 随机状态random method 随机方法random model 随机模式random movement 随意动作random noise 不规则噪声random number 随机数random numbers 乱数表random numbers table 随机号码表random observation 随机观察random observational error 随机观测误差random occurrence 随机出现random order 随机顺序random pairs method 随机选对法random phenomenon 随机现象random reinforcement 随机强化random sample 随机样本random sampling 随机抽样random sampling error 随机抽样误差random sampling method 随机抽样法random searching 随机调查random selection 随机选择random shape 无意义图形random variable 随机变量random wave 无规波randomization 随机化randomization test 随机化检定randomized block 随机区组randomized block design 随机区组设计随机分组设计randomized experiment 随机化实验randomized groups design 随机组设计randomized response 随机反应randomness 随机性random access memory 随机存取random group design 随机分组设计random halves reliability 随机半分卷信度random tracking 随机跟踪range 全距range effect 值域效应range of activity 活动范围range of attention 注意广度range of audibility 听觉范围range of body movement 身体运动范围身体运动范围range of choice 选择范围range of discrimination 辩别域range of error 误差范围range of indeterminacy 不确定性范围range of observation 观察范围range of reaction 反应幅度rank 等级rank correlation 等级相关rank difference correlation 级差相关rank image 等级象rank image principle 等级象原理rank order 等级次序rank order correlation 等级次序相关rank order method 等序法rank test 等级检验ranked distribution 等级分布Rankian therapy 郎氏治疗法ranking 等级评定ranking evaluation 排列评估ranking method 等级法rank sum test 等级总和检定Ranschburg inhibition 郎斯伯格抑制Ranvier s constriction 郎飞氏节Ranvier s node 郎飞氏节rap 扣击rap group 研究小组raphe 中缝raphe nucleus 中缝核raphe system 中缝系统rapid change 速度改变rapid eye movement 快速眼动眼速动rapid eye movement sleep 快速眼动睡眠rapid reading 快速阅读rapid change theory 急剧变迁论rapid smoking treatment 猛吸戒烟法猛吸戒烟法rapport 感情融通rapport stage 融洽阶段rapprochement 和睦rapture 着迷rapturous 狂喜raptus melancholicus 忧郁发作RAS 网状觉醒系统RAS 网状激活系统Rasch model 罗殊模型rat 大白鼠rate 率rate of audience 收听率rate of forgetting 遗忘率rate of growth 生长率rate of identity 知名率rate of increase 增长率rate of information transmission 信息传递率rate of population increase 人口增长率人口增长率rate of response 反应率rate of unemployment 失业率rate score 率数值rate test 速度测验ratee 受评者rater 估价人rater error 评审员误差rate limiting reaction 限度反应rating 评定rating error 评定误差rating method 评定法rating scale 评定量表rating scale method 等级量表法rating dating complex 追求富有对偶情结ratio 比率ratio aggregates 综合比率ratio analysis 比率分析ratio error 比率误差ratio estimation method 比值估计法ratio intelligence quotient 比率智商ratio IQ 比率智商ratio measure 比率测量ratio of interest for home group 内群亲近率ratio of interest for outside groups 外群亲近率ratio reinforcement 比率强化ratio reinforcement schedule 比率强化方式ratio scale 比率量表ratio variable 比率变量ration of interest for home group 内群亲近率rational 有理的rational analysis 理性分析rational approach 推理研究法rational authority 理性权威rational behavior 理性行为rational behavior therapy 合理行为治疗rational characteristics of character 性格的理智特征rational choice 理性选择rational construction 合理建构法rational education 理性教育rational emotive therapy 理情治疗法rational emotive therapy groups 理情治疗团体rational feeling 理智感rational knowledge 理性认识rational learning 理解学习rational number 有理数rational psychology 理性心理学rational psychotherapy 理性心理治疗法理性心理治疗法rational science 理性科学rational social management 合理的社会管理rational task analysis 理性作业分析rational type 理性型rational validity 合理效度rational will 唯理意志rationale 理论根据rationalism 理性主义rationalistic method 推理法rationalists 唯理主义者rationality 理性rationalization 合理化rationalization 文饰作用rationalization of crime 犯罪合理化rationalization of management 管理合理化rationalization of operation 操作合理化操作合理化rational behavior therapy理性行为治疗rational construct 合理建构法rational ec onomic man 理性经济人rational emotive therapy理性情绪治疗rational recall theory of learning 学习的理论回忆说rational theoretical model 推理理论模式推理理论模式Raven Advanced Progressive Matrices Test 瑞文高级推理测验Raven Colored Progressive Matrices Test 瑞文彩色推理测验Raven Progressive Matrices 瑞文推理测验Raven Standard Progressive Matrices Test 瑞文标准推理测验ravenous 贪食的raving 疯话raw data 原始资料raw deal 不公平待遇raw feel 直感raw observation 原始观察raw score 原始分数raw score method 原始分数法RBT (rational behavior therapy 理性行为治疗RCBF 区域性脑血流RCMR 区域性脑代谢率RCS 相对对比敏感度RDA 阅读年龄RdQ 阅读商数reach area 可达范围reach distance 可达距离reach envelope 可达包络线reach one s heart 自我反省reactance 对抗reactance theory 抗拒论reactant 反应物reacting substance 反应物质reaction 反应reaction center 反应中心reaction chain 反应链reaction formation 反向形成reaction hypothesis 反应假说reaction inhibition 反应抑制作用reaction key 反应键reaction latency 反应潜伏期reaction level 反应水平reaction method 反应法reaction norm 反应规范reaction of degeneration 变性反应reaction of flight 飞行反应reaction of flight 逃跑反应reaction pattern 反应模式reaction period 反应期reaction potency 反应潜能reaction potential 反应电位reaction psychology 反应心理学reaction range 反应范围reaction rate 反应速率reaction structure 反应结构reaction system 反应体系reaction threshold 反应阈reaction time 反应时间reaction time delay 反应时间延迟reaction time in old age 老年期的反应时间reaction time method 反应时法reaction time of action 动作反应时reaction to court decision 判决反应reaction to detention 拘禁反应reaction type 反应类型reaction velocity 反应速度reactional psychosis 反应性精神病reactionary 反动的reactionism 反动主义reactionist 反动分子reactivate 恢复活动reactive aggression 反应性攻击reactive behavior 反应性行为reactive depression 反应性抑郁症reactive disorder 反应性疾病reactive inhibition 反应性抑制反应性抑制reactive inhibition theory 反应性抑制说反应性抑制说reactive maladjusted disturbance 反应性适应障碍reactive need 反应性需求reactive psychosis 反应性精神病reactive schizophrenia 反应性精神分裂症reactive state 反应状态reactivity 反应性reactology 反应学reactor 反应者read aloud 朗读read back 复述read in 读入read only memory 只读存储器read out 读出readability 易读性readability of letter and numeral 字母数字易读性reader 读者readership 读者身份readership score 注目率readership survey 阅读率调查readiness 预备状态readiness for contest 争夺准备状态readiness grouping 预备性分组readiness program 准备程序readiness test 准备测验readiness to learn 学习准备reading 阅读reading ability 阅读能力reading achievement 阅读成就reading age 阅读年龄reading aloud 朗读reading comprehension 阅读理解reading disability 阅读无能reading disorder 阅读障碍reading efficiency 阅读效率reading grade 读书年级reading instruction 阅读教学reading interest 阅读兴趣reading ladder 阅读步骤reading level 阅读水平reading material 阅读材料reading measure 阅读测量reading mistake 阅读错误reading model 阅读模式Reading Psychology 阅读心理学reading quotient 阅读商数reading rate 阅读速度reading readiness 阅读准备reading skill 阅读技能reading span 阅读广度reading speed 阅读速度reading test 阅读测验Readings 读物reading disabled child 阅读障碍儿童阅读障碍儿童Reading Free V ocational Interest Inventory 非阅读性职业兴趣测验readout 读出readout 示值读数ready signal 准备信号reafference 再内导reafference 自传入感觉reafferent change 自传入感觉变化real anxiety 事实性焦虑real appearance 真象real behavior 真实行为real causes 真实原因real concept 真实的概念real goal 真实目标real judgment 真实判断real motion perception 真实运动知觉real movement 真动real movement perception 真动知觉real self 真实自我realism 现实主义realistic anxiety 现实性焦虑realistic consumers 现实主义消费者realistic thinking 现实性思维realistic writing and painting 写实reality 现实reality adaptation 现实适应reality anxiety 现实焦虑reality awareness 现实意识reality condition 现实性条件reality ego 现实我reality orientation 现实取向reality principle 现实原则reality sense 现实感reality testing 现实验证reality therapy 现实疗法reality therapy groups 现实治疗团体reality irreality 现实 非现实reality principle 唯实原则reality testing 自我的现实判断realizability 可实现性realization 现实化really exist 确实存在realm 领域realm of spirit 精神领域realness 真实性reappraisal 重新评价rear 抚养rear view 后视rearing 抚养rearrange 重新安排rearrangement 重新组织rearrangement form test 重组式测验rearrangement test 重组测验reason 理由reasonable cognition 理性认识reasonable stage 理性阶段reasonableness 理性reasoned thinking 推理思维reasoning 推理reasoning test 推理测验rebellion 反抗行为rebelliousness 判逆性rebirth fantasy 再生幻想rebound 回跳rebound effect 回跳效应rebound phenomenon 复发现象rebus 画迷rebus writing 谜画写字recall 回忆recall bias 回忆偏误recall method 回忆法recall period 回忆期recall test 回忆测验recall type 回忆类型recall value 回忆价recapitulation 复述recapitulation theory 复演说recapitulation theory of play 游戏的复演说receive 接受receiver 接受者receiver operating characteristic curve 接受者操作特征曲线receiver operating curve 接受者操作曲线recency 近因recency effect 近因效应recent amnesia 近事遗忘recent period 近期recentering 再定中心reception learning 接受式学习reception of experience 经验的接受reception strategy 接受策略reception test 验收检查receptive 感受的receptive aphasia 感受型失语症receptive cell 感受细胞receptive character 接纳性格receptive dysphasia 接受型语言障碍receptive field 感受域receptive language 接受语言receptive neuron 感受神经元receptive orientation 依赖取向receptive style 被动接受型receptive field orientation 感受野定向receptivity 感受性receptor 感受器receptor 受体receptor cell 感受细胞receptor fibre 感受神经纤维receptor inhibitor 受体抑制物receptor potential 受纳器电位receptor site 受点recessive 隐性recessive character 隐性特征recessive gene 隐性基因recessive inheritance 隐性遗传recessive trait 隐性特质RECG 放射心电图recidivism 屡犯recidivism rate 屡犯率recidivist 惯犯recipient 受者recipiomotor 运动感受的reciprocal 相互reciprocal action 交互作用reciprocal adaptation 相互适应reciprocal altruism 互利主义reciprocal assimilation 交互同化reciprocal compatibility 互利相容性reciprocal determinism 交叉决定论reciprocal emotion 互导情绪reciprocal induction 相互诱导reciprocal influence 交互影响reciprocal inhibition 交互抑制reciprocal inhibition therapy 交互抑制疗法reciprocal inter dependence 互惠式相互依赖关系reciprocal maximization 交互增大reciprocal nervous innervation 交互神经支配reciprocal role 相对角色reciprocal socialization 交互社会化reciprocal synapse 相反性突触reciprocal transformation 相互转化reciprocate 交互reciprocity 互易性reciprocity law 倒易定律reciprocity norm 回报常模reciprocity principle 互利原则recitation 背诵recitation method 背诵法reckets 佝偻病reclusion 隐退recoding 再编码recognition 再认recognition marks 识别标志recognition memory 再认记忆recognition method 再认法recognition sequence 识别顺序recognition span 再认广度recognition test 辨识测验recognition threshold 再认阈限recognition time 识别时间recognition type 再认类型recognition vocabulary 再认字汇recognitory assimilation 辨认同化recognizability 可识别性recognize 承认recollect 回忆recollection 回想recombination 重组recomposition 重新构成reconcy effect 新近效应recondition 重建条件reconditioning 重建条件反射reconnaissance at criminal scene 现场勘查reconsider 重新考虑reconstruct 重建reconstruction 重组reconstruction experiment 重组实验reconstruction in recall 回忆中的重建reconstruction method 重建法reconstruction of memory 记忆重建reconstruction of value 价值再构reconstructive memory 改造性记忆reconstructive psychotherapy 重建心理治疗法record 记录record description 记录描述record format 记录格式record group 记录组recorder 录音机recording 记录recording electrode 引导电极recording error 记录误差recording film 录音胶卷recording medium 记录存储器recording system 记录系统record keeping personnel 记录人员recovery 恢复recovery of humanity 人间性回复recovery quotient 复原商数recovery time 复原时间recreation 娱乐说recreation and relaxation theory of play 游戏娱乐和放松说recreation theory of play 游戏娱乐说recreational therapy 休闲治疗法recruitment 募集rectal temperature 直肠温度rectangular 矩形的rectangular distribution 矩形分配rectangular histogram 直方图rectification 调整rectilinear 直线的rectilinear correlation 直线相关rectilinear figure 直线图形rectilinear regression 直线回归rectilinear trend 直线趋势rectilinearity 直线性rection 直配recurrence 重现recurrent 屡发的recurrent inhibition 屡发抑制recurrent inhibition 再发性抑制recurrent psychosis 重发性精神病recurrent sensibility 回反敏感性recurring events 复现事件recursive grammar 递归语法recursive rule 衍生法则red 红red and black number table 红黑数字表红黑数字表red blindness 红色盲red nucleus 红核red out 红视red weakness 红色弱redefinition 再限定redefinition of group boundary 组界再限定redifferentiation 再分化redintegration 重整redintegrative memory 重整记忆redirection activity 变更活动redout 红视reduced 缩减的reduced condition 简化条件reduced cue 简化线索reduced form 简化形式reduced inspection 简化检验reduced law 简化律reduced parameter 简化参数reduced reflex time 简化反射时reduced sample 简化样本reduced sampling inspection 简化抽样检查reduced score 简约分数reducibility 可约性reducible data 简化数据reducible margin 可减少的限度reductase 还原酶reduction 还原reduction 减少reduction division 还原分裂reduction of stimulus condition 刺激条件的减缩reduction screen 减光屏reductionism 化约主义reductionism 还原论reductionist 还原论者reductive explanation 还原解释reductive interpretation 还原解说redundancy 多余性redundancy function 冗余位redundancy in language 语言的多余性语言的多 性redundant cue 冗余线索redundant instance冗余例证冗 例证redundant of information 信息余度reduplication 重迭red green blindness 红绿色盲red sighted 红色敏感者reeducation psychology 改造心理学reeducation through labor 劳动教养reefer 大麻烟卷reengineering 再造工程refer 涉及reference 参考reference axis 参照轴reference frame 参照系reference group 参照组reference group theory 参照群体理论reference instrument 标准仪器reference language 参考语言reference marks 参考符号reference measure 参照测量reference measurement method 参照测量法reference memory 参考记忆reference number 参考数字reference personality 参照人格reference plane 参考平面reference point 参照点reference standard 参考标准reference stimulus 参考刺激reference system 参考系统reference theory meaning 意义参照论reference units 参照单位reference value 参照值reference work 考证工作reference group theory 参照群体论referent 所指对象referent power 参照权力referral 转介referred pain 牵涉性疼痛referred sensation 移位感觉REFG 无线电脑电描记器refixation 再固着reflectance 反射reflected appraisal 反映评价reflected glare 反射眩光reflecting stereoscope 反射实体镜reflection 反映reflection coefficient 反射系数reflection of feeling 情感反映reflectionism 反映论reflective action 反省的作用reflective morality 反省道德reflective style 沉思型reflective teaching 反映性教学reflective think 反省思维reflectivity 反射性reflex 反射reflex action 反射动作reflex activity 反射活动reflex arc 反射弧reflex association 反射式联结reflex center 反射中枢reflex chain 反射链reflex circuit 反射回路reflex conduction 反射传导reflex contraction 反射性收缩reflex epilepsy 反射性癫痫reflex facilitation 反射助长作用reflex hallucination 反射性幻想reflex hysteria 反射性癔症reflex inhibition 反射性抑制reflex integration 反射整合reflex irradiation 反射扩散reflex latency 反射潜伏期reflex learning 反射学习reflex mechanism 反射机制reflex motor 反射运动reflex movement 反射性运动reflex of second order 二级反射reflex path 反射通路reflex reserve 反射准备reflex response 反射性反应reflex sensation 反射性感觉reflex sensitization 反射敏感现象reflex strength 反射强度reflex summation 反射积合reflex system 反射系统reflex time 反射时间reflex tonus 反射性紧张reflexion 反射作用reflexion inference 反思推论reflexion judgment 反思判断reflexion of factor 因素反转reflexive 反射性reflexive smiling 反射性微笑reflexivity 反射度reflexogenic 发生反射的reflexograph 反射描记器reflexology 反射学reflexophil 反射性的reflexotherapy 反射疗法reformation education 感化教育reformation through labour 劳动改造reformatory 教养所reformatory education 感化教育reformatory school 工读学校reforming motive of prisoner 罪犯改造动机refraction 折射refraction anomaly 折射异常refraction stereoscope 折射实体镜refractivity 折射性refractoriness 不应性refractoriness 失效refractory period 不应期refractory state 不感受状态refrangibility 折射性refreezing 重新冻结refuge 避难所refugee 避难者refusal of witness 不证refuse 拒绝refuse rate 拒绝回答率refutability 可反驳性refutation 辩驳refutation of argument ground 反驳论据反驳论据refutational defense 驳斥性防卫refute 驳斥regard 注意regeneration 再生regenerative process 再生过程regime 制度region 区域region of doubt 可疑域region of rejection 拒绝区region of rejection 排斥域region of significance 显著域regional analysis 地区分析regional cerebral blood flow 区域性脑血流regional cerebral metabolism rate 区域性脑代谢率regional difference 地区差异regional sociology 区域社会学regional structure of population 地区人口结构registration 登记regnant 支配的regnum animal 动物界regrate 囤积regrater 囤积者regress 退化regression 回归regression 退行regression analysis 回归分析regression coefficient 回归系数regression constant 回归常数regression curve 回归曲线regression effect 回归效应regression equation 回归方程regression estimate 回归估计regression fallacy 回归谬误regression forecasting 回归预测regression formula 回归公式regression line 回归线regression neurosis 退行性神经症regression time 回视时间regression to the mean 趋均数回归regression toward the mean 趋均数回归趋均数 归regression weights 回归加权regressive definition 回归定义regressive movement 回视运动regret 后悔regular 有规律的regular astigmatism 规则性散光regular inquiry 定期调查regular language 正规语言regularity 规律性regularity of mental transformation 心理转化规律regulating muscle 调节肌regulation 调节regulation for operations 操作规程regulation of food intake 摄食调节regulation of metabolism 新陈代谢调节新陈代谢调节regulation of water intake 饮水调节regulative development 调节发育regulative principle 规范原则regulative use of reason 理性的调节作用regulator 管理者regulatory factor 调节因子regulatory gene 调节基因regulatory inhibition 调节性抑制regulatory mechanism 调节机制rehabilitation 康复rehabilitation center 康复中心rehabilitation counseling 康复咨询rehabilitation medicine 康复医学rehabilitation psychology 康复心理学rehabilitational psychology 回归心理学 归心理学rehearsal 复述rehearsal method 复述法rehearsal set 复述定势reheotachygraphy 肌电波描记法Reid movement illusion 瑞德运动错觉瑞德运动错觉reification 观念与现象混淆Reil s insula 脑岛Reil s ribbon 内侧丘系reinforcement 强化reinforcement contrast 强化对比reinforcement of conditional reflex 条件反射的强化reinforcement of reflex 反射强化reinforcement schedule 强化程序reinforcement theory 强化理论reinforcement theory of motivation 激励的强化理论reinforcement value 强化值reinforcement affect theory 强化 感情论增强 感情论reinforcer 强化物reinforcing stimulus 强化刺激reinteation theory 返老还童说reintegration 重整作用rejecting confession 拒供rejecting neglecting p arent 拒忽型父母拒忽型父母rejection 拒绝rejection latitude 拒绝幅度rejection of peer 同伴拒绝rejection region 否定区域rejuvenation 恢复青春rejuvenescence 复壮现象relapse 恶化relapse 复发related color 相关色related data 相关数据related language 亲属语言relatedness 关联性relation 关系relation 亲属relation analysis 关系分析relation between generations 代际关系relation between inhibitory and excitation 抑制与兴奋的关系relation between plans and markets 计划与市场的关系relation theory of personality 个性的关系理论relational 亲属的relational 有关系的relational concept 关系概念relational fertility 关联丰富性relational learning 关系学习relational reflex 关系反射relational surveys 关系调查relational theory of transfer 迁移的关系理论relational word 关系词relationship 关系relationship 亲属关系relationship characteristic关系特征relationship psychotherapy 关系心理治疗relationship theory 关系论relationship therapy 关系治疗法relationship with co workers 与同事关系与同事关relative 相对的relative activity 相对灵活性relative adaptation 相对适应relative analysis 对比分析relative chance 相对机遇relative change 相对变化relative character 相对性状relative choice 相对选择relative concept 相对概念relative contrast sensitivity 相对对比敏感度relative deprivation 相对剥夺relative deprivation 相对性匮乏relative deprivation theory 相对剥夺说相对剥夺说relative discrimination 相对辨别relative dominance 相对优势relative error 相对误差relative frequency 相对频度relative gain 相对利益relative humidity 相对湿度relative judgment 相对判断relative limen 相对阈限relative localization 相对定位relative luminous efficiency function 相对视见函数relative maturity 相对成熟度relative measurement 相对量度relative metabolic rate 相对代谢率relative method 比较法relative motion 相对运动relative motion parallax 相对运动视差相对运动视差relative pitch 相对音高relative potency 相对优势relative property 相对性relative refractory period 相对不反应期相对不反应期relative retention time 相对保留时间relative self 相对自我relative sensitivity 相对感受性relative size 相对大小relative size cue 相对大小线索relative specificity 相对特效性relative stability 相对稳定性relative standard 相对标准relative threshold 相对阈限relative value 比值relative value 相对值relative variability 相对变异性relative variation 相对变异relative velocity 相对速度relative visual field 相对视野relativism 相对主义relativity 相对作用relativity law 相对律relativity of reinforcement 强化的相对性增强的相对性relativity theory 相对论relaxation 松弛relaxation factor 松弛因素relaxation of muscle action 肌肉动作放松relaxation of selection 选择放松relaxation oscillation 松弛颤动relaxation theory of play 游戏放松说relaxation therapy 放松疗法relaxation training 放松训练relaxed appearance with mental tension 形松意紧relaxed wave 松懈波relaxing reaction 松弛反应relaxing skill 松弛功relaxing techniques 松弛技术relay 继电器relay 交接relay cell 中间神经元relearning 再学习relearning method 再学法relearning procedure 再学习法release 释放release therapy 释放疗法releaser 释放体releaser 引发物releasing factor 释放因子releasing hormone 释放激素releasing mechanism 释放机制releasing schema 引发图式releasing stimulus 引发刺激relegation learning 归属学习relevance 有关relevancy 适切度relevant cue 关联线索relevant data 有关数据relevant dimension 关联维度relevant information 有关信息relevant subset 关联子集reliability 信度reliability coefficient 信度系数reliability consideration 可靠性思考reliability estimation 信度估计法reliability of data 数据的可靠性reliability of estimate 估计值的可靠性估计值的可靠性reliability of statistics 统计的可靠性reliability of test 检验的可靠性reliability of testimony 证言的可靠性reliability of testing 检验的可靠性reliability theory 可靠性理论religion 宗教religions belief 宗教信仰religions delusion 宗教妄想religions idea 宗教观念religions institution 宗教制度religions liberty 宗教自由religions quest 宗教研究religions skepticism 宗教怀疑主义religions taboo 宗教戒律religions thought 宗教思想religiosity 宗教狂religious cult 宗教崇拜religious fanaticism 宗教狂热religious instinct 宗教本能religious mania 宗教性躁狂状态religious melancholia 宗教性忧郁症religious psychology 宗教心理学religious therapy 宗教治疗法religious tradition 宗教传统REM 快速眼动快速眼动Remark s nerve fibre 雷马克氏神经纤维Remark s nerve fibre 无髓神经纤维remediable 可矫正的remedial 补习的remedial education 矫正教育remedial instruction 矫正教学remedial reading 补充阅读remedial reading 矫正阅读remedial teaching 矫正指导remediation 矫正remember 记得remembering 记住remembrance 追忆remembrance hallucination 追忆性幻觉追忆性幻觉reminiscence 记忆恢复remission 缓解remittent temperature 弛张温度remorse 悔恨remote amnesia 远事遗忘remote association 远隔联想Remote Association Test 远隔联想测验remote backward association 远距逆向联想remote cause 远因remote conditioning 远距条件作用remote control 遥控remote forward association 远距顺向联想remote memory 久远记忆remote sensing 遥感remote terminal 运程终端remoteness 远隔性removal 迁移removal from proactive inhibition 顺向抑制解除REMS (rapid eye movement sleep 快速眼动睡眠rencounter 冲突Rendu s tremor 郎杜震颤renifleur 嗅觉性欲癖患者Renshaw cell 仁邵细胞reorganization 重组reorganization theory 重组论Rep Test 角色构念测验reparation 弥补repeated examination 反复检查repeated interview 再面谈repeated measure 重复测量repeated measurement design 重复测量设计repeated observations 重复观测值repeated sampling 反复抽样repeated survey 重复调查repeated trials 重复试验repellent apraxia 相斥失用症repelling attack 排斥法repent 悔悟repercussion 反应repercussion effect 相互作用效果repercussion study 相互作用研究repertory grid 个人构念积储格repetition 重复repetition learning 反复学习repetition method of interrogation 复述讯问法repetition compulsion 强迫性重复动作强迫性重 动作repetitive error 重复误差repetitive part method 反复分习法repetitive process 重复过程repetitive rate 重复率repetitive task 反复作业replaceability 可替换性replacement 替代replacement 移位replacement sampling 替代抽样replicate 复制replication 重复replication experiment 验证性实验replication therapy 重演治疗法replicative enzyme 复制酶reply 回答repolarization 复极化repolarize 再极化report 报告represent 描述representability 表现力representability of dream 梦的表现力representation 表征representation function 描述功能representation in general 一般表象representation of athletic 运动表征representation of problem 问题表征representation of sense 感觉表现representation of sensibility 感性表象representation theorem 表现定理representational form 表象形式representational skill 表征技巧representative data 代表数据representative design 代表性设计representative element 表现成分representative factor 代表性因子representative intelligence 表象性智能表像性智能representative learning 表征学习representative measure 代表性测量representative participation 代表参与representative sample 代表性样本representative sampling 代表性抽样representative score 代表分数representative thinking 表象思维representative value 代表值representativeness 代表性representativeness of sample survey 抽样调查代表性representativeness of sampling 抽样代表性repress 抑制repressed complex 压抑情结repressed drive 压抑的内驱力repression 压抑repression resistance 压抑抗拒Repression Sensitization Scale 压抑 增敏量表。
Derepression of Neuronal Inhibitor due to miRNA Dysregulation in Schizophrenia-Related Microdeletion
Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related MicrodeletionBin Xu,1,3,5Pei-Ken Hsu,3,4,5Kimberly L.Stark,1,3Maria Karayiorgou,1,*and Joseph A.Gogos2,3,*1Department of Psychiatry2Department of NeuroscienceCollege of Physicians and Surgeons,Columbia University,1051Riverside Drive,New York,NY10032,USA3Department of Physiology and Cellular Biophysics,College of Physicians and Surgeons4Integrated Program in Cellular,Molecular,and Biophysical StudiesColumbia University,630West168th Street,New York,NY10032,USA5These authors contributed equally to this work*Correspondence:mk2758@(M.K.),jag90@(J.A.G.)/10.1016/j.cell.2012.11.052SUMMARY22q11.2microdeletions result in specific cognitive deficits and schizophrenia.Analysis of Df(16)A+/Àmice,which model this microdeletion,revealed abnormalities in the formation of neuronal dendrites and spines,as well as altered brain microRNAs. Here,we show a drastic reduction of miR-185,which resides within the22q11.2locus,to levels more than expected by a hemizygous deletion,and we demon-strate that this reduction alters dendritic and spine development.miR-185represses,through an evolu-tionarily conserved target site,a previously unknown inhibitor of these processes that resides in the Golgi apparatus and shows higher prenatal brain expres-sion.Sustained derepression of this inhibitor after birth represents the most robust transcriptional disturbance in the brains of Df(16)A+/Àmice and results in structural alterations in the hippocampus. Reduction of miR-185also has milder age-and region-specific effects on the expression of some Golgi-related genes.Ourfindings illuminate the contribution of microRNAs in psychiatric disorders and cognitive dysfunction.INTRODUCTIONThe identification of a widespread role of chromosomal microde-letions and microduplications(copy number variants or CNVs)in determining susceptibility to psychiatric disorders such as schizophrenia(SCZ),as well as neurodevelopmental disorders such as autism and intellectual disability,represents a shift in our understanding of the genetic architecture of these disorders and highlights the pervasive contribution of rare and highly pene-trant structural mutations(Karayiorgou et al.,1995;Morrow, 2010;Rodriguez-Murillo et al.,2012).Along these lines,a strong link has been established between microdeletions in chromo-some22q11.2,cognitive dysfunction and psychiatric disorders, especially SCZ(Karayiorgou et al.,1995,2010;Xu et al.,2008). Understanding how the genes disrupted by this deletion contribute to the ensuing psychiatric and cognitive phenotypes will provide important mechanistic insights and guide analysis of other pathogenic mutations(Arguello and Gogos,2006, 2010,2012;International Schizophrenia Consortium,2008; Karayiorgou et al.,2010).By using chromosomal engineering,we generated a mouse model carrying a hemizygous1.3Mb chromosomal deficiency on mouse chromosome16(Df(16)A),which is syntenic to the 1.5Mb22q11.2microdeletion(Stark et al.,2008).Analysis of Df(16)A+/Àmice showed abnormalities in dendritic morphogen-esis and formation of dendritic spines of hippocampal pyramidal neurons both in culture and in vivo(Mukai et al.,2008;Stark et al., 2008).Such changes may account,at least in part,for the regional decreases in gray matter volumes observed in some 22q11.2deletion carriers(Bearden et al.,2009;Chow et al., 2002)and may ultimately lead to altered information processing. Analysis of the Df(16)A+/Àstrain also provided compelling evidence that the22q11.2microdeletion results in abnormal pro-cessing of brain microRNAs(miRNAs),a class of small noncod-ing RNAs that regulate the stability and translation of mRNAs (Fineberg et al.,2009;Kosik,2006;Schratt,2009;Xu et al., 2010),implicating miRNA dysregulation in the pathogenesis of psychiatric disorders and cognitive dysfunction.One gene dis-rupted by the22q11.2microdeletion is DGCR8,a component of the‘‘microprocessor’’complex that is essential for miRNA production(Tomari and Zamore,2005).Dgcr8haploinsufficiency results in the downregulation of a specific subset of mature miRNAs and contributes to alterations found in Df(16)A+/Àmice (Fe´nelon et al.,2011;Stark et al.,2008).miRNA dysregulation likely accounts for a fraction of the transcript misexpression in the brains of Df(16)A+/Àmice(Stark et al.,2008),but direct targets have not been reported.Here,we highlight an important component of this dysregulation and identify a previously un-characterized gene with prenatal expression bias as amajor262Cell152,262–275,January17,2013ª2013Elsevier Inc.miRNA target mediating the effects of the 22q11.2microdeletion on neuronal maturation and connectivity.RESULTSA Drastic Reduction of miR-185Levels in Df(16)A +/ÀMiceStudies in the Df(16)A +/Àmouse strain have shown that the 22q11.2microdeletion results in abnormal processing of a specific subset of brain miRNAs due to the removal of one copy of the Dgcr8gene causing a decrease in its expression in the adult brain (Stark et al.,2008)as well as in early development (Figure S1A available online).It is noteworthy that,in addition to Dgcr8,the 22q11.2microdeletion and the equivalent mouse deficiency remove one copy of a miRNA gene (miR-185)located within the minimal 1.5Mb 22q11.2critical region (Figure 1A).In situ hybridization assays indicated that miR-185is expressed in several brain regions such as hippocampus (HPC)and cortex (Figure 1B).qRT-PCR analysis showed that expression of miR-185is dramatically reduced by $70%–80%in both HPC(p <10À6)and prefrontal cortex (PFC;p <10À11)of adult Df(16)A +/Àmice as compared to wild-type (WT)littermates (Figures 1C and 1D).This reduction was also observed at earlier develop-mental stages (embryonic day 17[E17]and postnatal day 6[P6])(Figure S1B).miR-185also showed a more modest decrease in Dgcr8+/Àmice ($20%in HPC;p <0.05;Figure 1E),suggesting that the severe reduction of mature miR-185expression in Df(16)A +/Àmice may be due to a combined effect of hemizygos-ity of the miR-185gene and impaired maturation of the pri-mir-185transcript produced from the remaining copy,due to the reduction in Dgcr8levels.Such a large reduction in expression of a resident gene to levels greater than expected by the 50%decrease in gene dosage is unique among genes affected by the 22q11.2microdeletion.A Primary Transcriptional Consequence of 22q11.2Genomic LossPrevious microarray analysis of adult Df(16)A +/Àmice revealed genome-wide alterations of transcriptional programs in the HPC and PFC (Stark et al.,2008).We extendedexpressionFigure 1.Drastic Reduction of mir-185Expression in Df(16)A +/ÀMice(A)Schematic diagram showing the 1.5Mb 22q11.2critical region and the syntenic mouse locus.The 1.5Mb deletion is mediated by low copy repeat sequences LCR-A and LCR-B (illustrated as black boxes).Dgcr8and miR-185(hosted in the intron of the 22orf25gene in human and the D16H22S680E gene in mouse)are highlighted in red.Chr22,chromosome 22;Chr16,chromosome 16.(B)Expression of miR-185mRNA in HPC and cortex as shown by in situ hybridization in coronal brain sections using an antisense miR-185probe.An antisense U6probe and a scramble probe were used as positive and negative controls,respectively.Images were taken at either 43(left)or 103(right)magnification.(C–E)miR-185expression levels in HPC (C)or PFC (D)of Df(16)A +/À(n =7for mutant,n =9for WT)and in HPC (E)of Dgcr8+/À(n =10for mutant and WT),as assayed by qRT-PCR.Expression levels in mutant mice were normalized to their respective WT littermates.Results are expressed as mean ±SEM.*p <0.05,**p <0.01,and ***p <0.001(Student’s t test).See also Figure S1.Cell 152,262–275,January 17,2013ª2013Elsevier Inc.263Figure2.2310044H10Rik Is Robustly Upregulated in the Brain of Df(16)A+/ÀMice(A)Changes in gene expression in the PFC(upper panel)or HPC(lower panel)of Df(16)A+/Àand WT littermate control mice at E16,P6,and adulthood(n=10each group).Volcano plot of the p values and the corresponding relative expression of each gene are shown.Light blue dots indicate genes within Df(16)A deficiency, light green dots indicate upregulated miRNA-containing transcripts,and red dots indicate probe sets representing Mirta22.(B)Top ten protein-encoding genes that show significant upregulation in the PFC(upper panel)or HPC(lower panel)of Df(16)A+/Àand WT littermate mice at E16, P6,and adulthood.Mirta22is highlighted in red.(legend continued on next page)264Cell152,262–275,January17,2013ª2013Elsevier Inc.profile analysis of these two brain regions to two earlier develop-mental stages,E17and P6.Only one gene,2310044H10Rik,was consistently significantly upregulated(in at least two of the three developmental stages examined and in at least one of the two brain areas tested).Indeed,2310044H10Rik was among the top upregulated genes in both postnatal stages examined (Figures2A and2B).Notably,no significant difference in 2310044H10Rik expression was found in either frontal cortex or HPC at E17(Figures2A and2B).Importantly,there is no known miRNA within or surrounding this genomic locus,sug-gesting that the upregulation is not due to impaired processing of overlapping pri-miRNA transcripts.In independent experiments,we attempted to distinguish primary versus secondary gene targets of the22q11.2microde-letion by looking for genes whose expression changes in oppo-site direction as a result of genomic losses or gains in this locus. Such genes are likely to represent primary targets and direct transcriptional readouts of the underlying copy number imbal-ances(Chahrour et al.,2008).We compared the PFC and HPC gene expression profiles in mice carrying a deletion or duplica-tion at the22q11.2syntenic mouse locus using as reference compound heterozygous mice balanced for copy number (see Extended Experimental Procedures;Figure S2).We identi-fied a number of inversely altered transcripts in either PFC or HPC(p<0.001;Extended Experimental Procedures;Table S1),in addition to the transcripts from the22q11.2region.As expected,the majority of the identified transcripts are pri-miRNA forms.Only12transcripts were significantly misregu-lated in a reciprocal manner in both PFC and HPC(Table S2). Among them,2310044H10Rik is the only gene with protein-coding potential.Taken together,our expression profiling highlighted the misre-gulation of2310044H10Rik as a major consequence of the 22q11.2genomic imbalances at the transcriptome level.We confirmed the pattern of2310044H10Rik upregulation in both PFC and HPC by TaqMan qRT-PCR(PFC:E17,20%,p=0.24; P6,59%,p<0.01;Adult,76%,p<10À6;HPC:E17,20%,p= 0.16;P6,50%,p<0.05;Adult,38%,p<0.05;Figures2C and 2D).This analysis revealed a profile of temporal regulation with prenatal expression bias where levels of2310044H10Rik rapidly decline during thefirst week after birth and remain constantly low thereafter,as well as a corresponding pattern of misregula-tion in Df(16)A+/Àmice where prenatally elevated expression persists throughout postnatal and adult life.Increased brain expression of2310044H10Rik is recapitulated in Df(16)A+/Àprimary neurons(Figure2E).2310044H10Rik Is a Major Downstream Effectorof miRNA DysregulationNotably,2310044H10Rik mRNA levels were also elevated in Dgcr8+/Àmice(HPC:30%,p<0.05;PFC:24%,p<0.05;Fig-ure S3A),suggesting that upregulation may be due to miRNA dys-regulation.Indeed,two miRNA target site prediction programs, TargetScan(Grimson et al.,2007)and mirDB(Wang,2008),report that the30UTR of2310044H10Rik contains binding sites of miRNAs shown to be affected in Df(16)A+/Àmice by microarray profiling(Stark et al.,2008).Specifically,mirDB predictedfive such miRNAs with binding sites in the30UTR of2310044H10Rik including miR-185and miR-485,whereas TargetScan predicted 13miRNA sites,including sites for miR-185,miR-485,miR-491, and miR-224.Notably,both programs predicted sites for miR-185and miR-485(Figure3A,red rectangles).Because increased brain expression of2310044H10Rik is recapitulated in Df(16)A+/Àprimary neurons(Figure2E),wefirst used primary neurons to determine whether endogenous 2310044H10Rik expression is actually under the control of miR-185.To examine the effect of miR-185overexpression on 2310044H10Rik level,we introduced into primary neuronal cultures a miRNA precursor mimic(‘‘pre-mir-185’’),which is pro-cessed into mature miRNA,or a scramble precursor(‘‘prescram-ble’’)with no homology to the mouse genome,which serves as a control for nonspecific effects of small RNA expression. Twenty-four hours posttransfection,there was a decrease in the levels of2310044H10Rik in pre-mir-185-transfected neurons when compared to prescramble-transfected neurons(p<0.01; Figure3B).In a complementary experiment,introduction of an anti-miR-185LNA oligo or a scramble control oligo resulted in an increase of2310044H10Rik mRNA levels in anti-miR-185-transfected cells when compared to scramble-transfected cells (p<0.05;Figure3C).Taken together,these results confirm that2310044H10Rik expression in primary neurons is under the repressive control of miR-185.Essentially identical results were obtained when2310044H10Rik expression was assayed in N18cells(Figures3D and3E).Therefore,we used this cell line to further characterize the miR-185-mediated inhibition.To test whether the inhibition of miR-185on2310044H10Rik expression is30UTR dependent as predicted by TargetScan and mirDB(see above),2310044H10Rik30UTR-fused luciferase reporter genes were cotransfected with either pre-mir-185mimic or prescramble into N18cells.Although prescramble did not affect the reporter activity,introduction of pre-mir-185mimic led to a dramatic decrease of luciferase activity as compared to the prescramble control(p<0.001for all pre-mir-185concen-trations used;Figure3F).To investigate whether miR-185-medi-ated repression is specific and operates directly via the two binding sites predicted by TargetScan(Figure3A),we engi-neered luciferase reporters carrying mutated versions of 2310044H10Rik30UTR with either individual or both miR-185 binding sites mutated(Mut1:Site1mutant;Mut2:Site2mutant; Mut1&2:Site1and2mutants,see Extended Experimental Procedures).The pre-mir-185mimic significantly reduced the luciferase activity of the WT reporter to$25%relative to a control reporter without30UTR,whereas it reduced the luciferase activ-ities of the Mut1and Mut2reporters to80%(p<0.01)and33%(C and D)Temporal expression of2310044H10Rik(Mirta22)in the PFC(C)and HPC(D)of Df(16)A+/Àand WT littermate mice as monitored by qRT-PCR(n=9–10 for each group).(E)Increased expression of endogenous2310044H10Rik(Mirta22)in DIV9hippocampal neurons isolated from Df(16)A+/Àanimals as assayed by qRT-PCR(n=3 each genotype).Expression levels in mutant neurons were normalized to WT neurons.Results are expressed as mean±SEM.*p<0.05,**p<0.01,and***p<0.001(Student’s t test).See also Figure S2and Tables S1and S2.Cell152,262–275,January17,2013ª2013Elsevier Inc.265(p <0.05),respectively (Figure 3G).Notably,the pre-mir-185mimic could not repress luciferase activity driven from a mutant reporter where both binding sites are simultaneously disrupted (Figure 3G).Thus,both miR-185cognate binding sites have an impact on the 30UTR-mediated regulation of 2310044H10Rik expression,although the site disrupted in the Mut1reporter (Site 1)seems to be the major target site via which miR-185directly exerts its repressive effect.We further addressed the dependence of 2310044H10Rik 30UTR reporter repression on the levels of miR-485or miR-491,which are also predicted to target binding sites in the 30UTR ofthe 2310044H10Rik gene.Both of these miRNAs are modestly downregulated in the HPC of the Df(16)A +/Àmice due to Dgcr8hemizygosity (Figure S3B).The pre-miRNA mimics of either miRNA modestly but significantly reduced the luciferase activity of the 30UTR-fused reporter compared to the prescramble control (pre-mir-485:27%,p <0.05;pre-mir-491:35%,p <0.05;Figure 3H).A three-factor ANOVA indicated that all three miRNAs (miR-185,miR-485,and miR-491)and their inter-actions have significant impact on the luciferase activity with the exception of the interaction between miR-485and miR-491(Table S3).Figure 3.miR-185Directly Targets and Represses 2310044H10Rik(A)Structure of the 30UTR of 2310044H10Rik (Mirta22)showing miRNA binding sites predicted by TargetScan or mirDB.Blocks in mouse 2310044H10Rik (Mirta22)30UTR that are highly conserved in rat and human orthologs are shown below the mouse 30UTR.Evolutionary conservation is also assessed by the ‘‘30-way multiz alignment and conservation analysis’’in the USCS browser,with conserved blocks indicated by green peaks.miR-185and miR-485binding sites located within the conserved blocks are shown in red.(B and C)qRT-PCR quantification of endogenous 2310044H10Rik (Mirta22)in DIV7hippocampal neurons.Expression levels in anti-miR-185-treated and pre-mir-185-treated neurons were normalized to expression levels under respective controls.(B)Increased expression levels of Mirta22in neurons transfected with anti-miR-185at DIV5(n =5,each treatment).(C)Reduced expression levels of Mirta22in DIV9hippocampal neurons transfected with pre-mir-185mimic at DIV7(n =3,each treatment).(D and E)qRT-PCR quantification of endogenous 2310044H10Rik (Mirta22)in N18cells.Expression levels in pre-mir-185-treated and anti-miR-185-treated cells were normalized to expression levels under respective controls.(D)Reduced expression levels of Mirta22in cells transfected with pre-mir-185mimic (n =3,each treatment).(E)Upregulation of Mirta22in cells transfected with an anti-miR-185LNA oligo (n =3,each treatment).(F–H)Repression effects of pre-mir-185,pre-mir-485,and pre-mir-491on Mirta2230UTR were examined by a dual-luciferase reporter assay (see Experimental Procedures ).Values are Renilla luciferase levels relative to firefly luciferase levels and normalized to the relative expression levels under prescramble treatment (F and H)or to the relative expression levels from plasmid with no 30UTR (G)(n =3for each condition).Pre-mir-185significantly decreases the 2310044H10Rik (Mirta22)30UTR reporter expression over a concentration range of 10–0.01nM (F).Pre-mir-185-mediated repression on 2310044H10Rik (Mirta22)30UTR reporter expression depends on conserved miRNA binding sites (G).Pre-mir-485and pre-mir-491significantly decrease the 2310044H10Rik (Mirta22)30UTR reporter expression (H).Results are expressed as mean ±SEM.*p <0.05,**p <0.01,and ***p <0.001(Student’s t test).See also Figure S3and Table S3.266Cell 152,262–275,January 17,2013ª2013Elsevier Inc.Taken together,thesefindings suggest that the persistent elevation of2310044H10Rik levels observed in Df(16)A+/Àmice is likely the result of the combined hemizygosity at miR-185 and Dgcr8loci.Although more than one miRNA contributes, the major effect is due to the dramatic downregulation of miR-185.Consistent with this notion and the less profound reduction of miR-185in Dgcr8+/Àmice(Figure1E),2310044H10Rik is only modestly upregulated in this strain(Figure S3A).Interestingly, a comparison between the30UTR of human and mouse ortho-logs(Figure3A)reveals that miR-185cognate Site1as well as one miR-485binding site are located within a highly conserved region,suggesting that these sites are critical in regulating the levels of the human ortholog(C19orf63).Consistent with this expectation,introduction of pre-mir-185into human293T cells resulted in a significant decrease of endogenous C19orf63levels (Figure S3C).In addition,similar to the pattern observed in the mouse brain,expression of C19orf63decreases in infant brain as depicted in BrainSpan database(). It is noteworthy that inspection of our gene expression data set as well as qRT-PCR analysis of a sample of eight high-likeli-hood miR-185targets identified by more than one prediction program did not reveal any additional significant changes of transcript levels in the brains of Df(16)A+/Àmice(Figure S3D). Furthermore,unlike2310044H10Rik,none of the other top upre-gulated protein-coding genes(shown in Figure2B)are consis-tently altered in both HPC and frontal cortex of E17,P6,and adult Df(16)A+/Àmice,and only one of them(B3gat1,see below)is predicted to contain miR-185seed sites in its30UTR.Overall, although additional downstream targets of miR-185likely exist (see below),our analysis suggests that2310044H10Rik re-presents the major downstream effector of miR-185and a major hub target of miRNA dysregulation due to the22q11.2 microdeletion.Due to confirmed miRNA-mediated regulation, we renamed the gene Mirta22(miR NA ta rget of the22q11.2 microdeletion).Mirta22Encodes a Neuronal Protein Residingin the Golgi ApparatusMirta22encodes a28kDa protein without any known sequence homology or functional domain(/uniprot/ Q3TAS6).The murine ortholog is located on mouse chromo-some7and contains seven coding exons.The human ortholog (C19orf63)is located on chromosome19q13.33and encodes a protein with92.3%identity to the murine protein(Figure4A). One mouse reference sequence(isoform1)is reported in Gen-Bank,whereas two C19orf63isoforms(isoform1and2)are re-ported in GenBank and in the literature(Junes-Gill et al.,2011). The protein encoded by isoform1is predicted to contain a N-terminal signal peptide,as well as a transmembrane segment (Figure4A,red rectangles),which separates a long N-terminal region from a short C-terminal segment that contains a polygly-cine tail with unknown function.Isoform2differs from isoform1 by an alternatively spliced exon located after exon6.The protein encoded by isoform2is shorter by eight amino acids,contains the N-terminal signal peptide but not the transmembrane segment,and is predicted to be secreted(Figure4A).We raised a polyclonal antibody against a segment of the protein that is conserved in the mouse and human orthologs(amino acids 207–226,Figure4A,green rectangle;see Extended Experi-mental Procedures;Figure S4).We validated the specificity of the antibody using a number of assays(see Extended Experi-mental Procedures;Figures S4A–S4C)and showed that it can also detect the secreted form of the protein in293T cell cultures (Figure S4D).Western blot assays of protein extracts from the brain of Df(16)A+/Àmice and WT littermates showed the expected increase(25%)in Mirta22levels in mutant mice(Fig-ure4B).A similar magnitude increase of the Mirta22immunocy-tochemical signal was observed in Df(16)A+/Àcultured neurons, as compared to WT neurons(Figure4C).Immunostaining of neuronal cultures showed that Mirta22is primarily a neuronal protein(Figure4D,top).At the subcellular level,it is found primarily in the soma,where it colocalizes with the Golgi apparatus marker GM130(Nakamura et al.,1995).As the neurons mature,it is also found in vesicles and tubular-like clusters within the dendritic shafts(Figure4D,middle).Mirta22 immunoreactivity was not detected in cultures stained with pre-immune serum(Figure S4E)and was diminished by64%in Mirta22shRNA-transfected neurons(Figures S4F and S4G, lower panel).Immunohistochemical analysis demonstrated that Mirta22is widely distributed in the brain,where it is localized in neurons(Figure4D,bottom).miR-185Reduction Results in Coordinated Mild Dysregulation of Golgi-Related GenesAccumulating evidence suggests that miRNAs may target functionally connected genes,often in a developmental stage-specific manner(Tsang et al.,2010;Zhang et al.,2009).Consis-tent with this notion,functional annotation clustering analysis of2,695out of2,708predicted miR-185targets(TargetScan Mouse v.5.2)included in the DAVID Mus musculus gene functional annotation database() identified as the top enriched gene cluster(gene count=159, Enrichment Score=8.56,FDR-corrected p=2310À9)the Gene Ontology(cellular component)term‘‘Golgi apparatus’’(Figure5A).Gene set enrichment analysis(GSEA)on the2,708 predicted miR-185targets ranked based on the gene expression profile of Df(16)A+/Àmice also indicated that the Gene Ontology terms‘‘Golgi apparatus part’’and‘‘Golgi apparatus’’were among the top20gene sets in the adult HPC(Figure5A).A global perspective on the enrichment of this miR-185target gene set among the differentially expressed genes in the Df(16)A+/Àmice showed a significant enrichment in the adult HPC expres-sion profile(p=5310À4)where,as expected,most of the top genes were upregulated(n=34),and only four genes were down-regulated(p<0.005,Figure5B;Table S4).A considerably more modest enrichment was suggested for the E17(p=0.02)and P6 HPC(p=0.016)profiles(Figure S5).Interestingly,there was no significant enrichment within the PFC profiles in any of the three ages tested(E17:p=0.6311;P6:p=0.1326;adult:p=0.244). Expression changes were modest,with only4of159Golgi-related probe sets included among the top100in the adult HPC. Altered miR-185Levels Contribute to Structural Alterations of Df(16)A+/ÀNeuronsDf(16)A+/Àmice show impaired formation of dendrites and spines in the HPC(Mukai et al.,2008)and the PFC(Figures Cell152,262–275,January17,2013ª2013Elsevier Inc.267S6A–S6C),which are faithfully recapitulated in primary neuronal cultures.Impairment in these processes in Df(16)A +/Àmice could only be partially accounted for by the 50%decrease in the levelsof Dgcr8(Fe´nelon et al.,2011;Stark et al.,2008).Localization of Mirta22within the Golgi apparatus and dendritic shafts suggeststhat diminishment of the miR-185repression on Mirta22levels may also contribute to these deficits.To test this hypothesis,we first asked whether reduction of miR-185levels results in deficits in dendritic and spine develop-ment similar to those observed in Df(16)A +/Àneurons (MukaiFigure 4.Genomic Structure,Neuronal Expression,and Subcellular Localization of 2310044H10Rik(A)Top view shows the structure of mRNA transcripts of 2310044H10Rik (Mirta22)and its human ortholog,C19orf63.RefSeq reports a 2310044H10Rik (Mirta22)transcript with seven exons (blue rectangles),which is predicted to encode a signal peptide and a transmembrane domain (red rectangles).The peptide epitope used to generate a polyclonal antibody is marked by a green rectangle.For C19orf63,RefSeq reports two alternatively spliced transcripts:one that encodes a predicted transmembrane protein and one with an additional exon that encodes a predicted secreted protein.Bottom view shows protein sequence alignment of predicted transmembrane isoforms encoded by 2310044H10Rik (Mirta22)and its human ortholog.Black blocks indicate completely conserved residues,gray blocks indicate similar residues (defined by Boxshade default similarities),and white blocks indicate different residues.(B)Upper view presents representative western blot assays of 2310044H10Rik (Mirta22)in PFC lysates prepared from Df(16)A +/Àanimals and WT littermates.a -tubulin is used as loading control.Lower view is quantification of 2310044H10Rik (Mirta22)protein level in PFC of Df(16)A +/Àand WT animals (n =9each genotype).Expression levels in mutant mice were normalized to WT littermates.Results are expressed as mean ±SEM.**p <0.01(Student’s t test).(C)Quantification of 2310044H10Rik (Mirta22)immunocytochemical signals in Df(16)A +/Àand WT cultured neurons (n =31for Df(16)A +/À;n =34for WT).Expression levels in mutant neurons were normalized to WT neurons.Results are expressed as mean ±SEM.*p <0.05(Student’s t test).(D)Upper panel shows that 2310044H10Rik (Mirta22)colocalizes with neuron-specific marker NeuN,but not with glia-specific marker GFAP,in cultured hippocampal neurons at DIV20.Middle panel shows that 2310044H10Rik (Mirta22)(green)colocalizes with Golgi-specific marker GM130(red)in the soma.2310044H10Rik (Mirta22)is also found in vesicles and tubular-like clusters in the dendrites,which are highlighted by the dendritic marker MAP2(blue).Lower panel presents distribution of 2310044H10Rik (Mirta22)protein in adult mouse brain.Sections were stained with 2310044H10Rik (Mirta22)antibody.Images were taken at 43,103,203,and 403magnifications as indicated.Red boxes in 43,103,and 203images outline the area shown in 103,203,and 403images,respectively.See also Figure S4.268Cell 152,262–275,January 17,2013ª2013Elsevier Inc.。
Schizoaffectivedisorder:分裂情感障碍
Dr.Varunee Mekareeya ,M.D.,FRCPsychTSchizoaffective disorderSchizoaffective disorder is a psychiatric disorder that affects about 0.5 to 0.8 percent of the population. It is characterized by disordered thought processes and abnormal emotional responses. Common symptoms include delusions ,hallucinations ,disorganized speech ,and bizarre behaviors ,as well as mood problems.Schizoaffective disorder is divided into two mood disorder types : bipolar or depressive. Symptoms of schizoaffective disorder usually begin in young adulthood.In DSM-5 and ICD-10 ,schizoaffective disorder is in the same diagnostic class as schizophrenia ,but not in the same class as mood disorders.EpidemiologySchizoaffective disorder appears to be about one-third as common as schizophrenia. Lifetime prevalence of schizoaffective disorder is uncertain ,but probably less than 1 percent ,in the range of 0.5 to 0.8 percent. The incidence of the disorder is higher in females than in males ,mainly due to an increased incidence of the depressive type among females. The typical age at onset of schizoaffective disorder is early adulthood ,although onset can occur anywhere from adolescence to late in life.EtiologyGenetic ,neurobiology ,early and current environment ,behavioral ,social ,and experiential components appear to be important contributory factors. Biological and environmental factors interact with an individual´s genes in ways which may increase or decrease the risk for developing schizoaffective disorder. Schizophrenia spectrum disorders ,of which schizoaffective disorder is a part ,have been increasingly linked to advanced paternal age at the time of conception ,a known cause of genetic mutations.Among people with schizophrenia ,there may be an increased risk for schizoaffective disorder in first–degree relatives. The risk for schizoaffective disorder may be increased among patients who have a first–degree relative with schizophrenia ,bipolar disorder ,or schizoaffective disorder.The physiology of persons with schizoaffective disorder appears to be not identical to that of those with schizophrenia and bipolar disorder.Clinical featuresSchizoaffective disorder is distinguished by mood disorder–free psychosis in the context of a long–term psychotic and mood disorder. Psychosis may include delusions ,hallucinations ,disorganized speech ,thinking or behavior and negative symptoms. Negative symptoms include a lack of spontaneous speech ,reduced intensity of outward emotional expression ,loss of motivation ,and inability of experience pleasure. Negative symptoms can be more lasting and more debilitating than positive symptoms.Mood symptoms are of mania ,hypomania ,mixed state or depression ,and tend to be episodic rather than continuous. Symptoms of mania include elevated or irritable mood ,inflated self–esteem ,agitation ,risk–taking behavior ,decreased need for sleep ,poor concentration ,rapid speech ,and racing thoughts.Symptoms of depression include▪ low mood or apathy▪ loss of pleasure in activities which the individual once enjoyed▪ changes in appetite or weight▪ disturbances in sleep▪ changes in motor activity or decreased energy▪ fatigue▪ guilt or worthlessness and suicidal thinking▪ difficulty making decisions and concentratingDiagnosisDiagnosis is based on mental health clinician’s observation of patient’s behavior while the patient is experiencing active symptoms. Diagnosis is also based on t he patient’s self–reported experiences ,behavioral abnormalities reported by family members ,friends or co–workers. The criteria for diagnosis depend on both the presence and duration of certain signs and symptoms.The most widely–used criteria for diagnosing schizoaffective disorder are from the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders–5 (DSM-5). Diagnostic CriteriaA.An uninterrupted period of illness during which there is a major mood episode (major depressive ormanic) concurrent with Criterion A of schizophrenia.Note: The major depressive episode must include Criterion A1:Depressed mood.B.Delusions or hallucinations for 2 or more weeks in the absence of a major mood episode (depressiveor manic) during the lifetime duration of the illness.C.Symptoms that meet criteria for a major mood episode are present for the majority of the totalduration of the active and residual portions of the illness.D.The disturbance is not attributable to the effects of a substance (e.g.,a drug of abuse , amedication) or another medical condition.Specify whether:Bipolar type : This subtype applies if a manic episode is part of the presentation. MajorDepressive episodes may also occur.Depressive type : This subtype applies if only major depressive episodes are part of thepresentation.Associated Features Supporting DiagnosisOccupational functioning is frequently impaired. People with schizoaffective disorder have restricted social contact and difficulties with self-care. They also have less severe and less negative symptoms than schizophrenic patients. Individuals with schizoaffective disorder may be at increased risk for later developing episodes of major depressive disorder or bipolar disorder. There may be associated alcohol and other substance-related disorder.Differential DiagnosisA wide variety of psychiatric and medical conditions can manifest with psychotic and mood symptoms that must be considered in the differential diagnosis of schizoaffective disorder. These include ▪ psychotic disorder due to another medical condition▪ delirium▪ major neurocognitive disorder▪ substance / medication-induced psychotic disorder▪ bipolar disorders with psychotic features▪ major depressive disorder with psychotic features▪ depressive or bipolar disorders with catatonic features▪ schizotypal ,schizoid ,or paranoid personality disorder▪ brief psychotic disorder▪ schizophreniform disorder▪ schizophrenia▪ delusional disorder▪ other specified and unspecified schizophrenia spectrum and other psychoticdisorder▪ psychotic disorder due to another medical conditionDistinguishing schizoaffective disorder from schizophrenia and from depressive and bipolar disorders with psychotic features is often difficult. Criteria C is designed to separate schizoaffective disorder from schizophrenia ,and Criteria B is designed to distinguish schizoaffective disorder from a depressive or bipolar disorder with psychotic features.ComorbidityMany patients with schizoaffective disorder are also diagnosed with other mental disorders ,especially substance use disorders and anxiety disorders. The incidence of medical conditions is increased in schizoaffective disorder.People with schizoaffective disorder generally respond best to a combination of medical treatment and long-term psychosocial and social supports.Medical treatmentMedicationMedications are chosen to reduce psychotic symptoms and stabilize mood symptoms.Electroconvulsive therapyElectroconvulsive therapy (ECT) may be considered for patients with schizoaffective disorder experiencing severe depression or severe psychotic symptoms that have not responded to medications. Psychosocial TreatmentCognitive behavioral therapy is helpful. Building a trusting relationship in therapy can help patients with schizoaffective disorder better understand their condition and feel helpful about their future. Effective sessions focus on real-life plans ,problems and relationships. Intensive case management (ICM) has been shown to reduce hospitalizations , improve adherence to treatment ,and improve social functioning.High quality psychiatric rehabilitation is very important for recovery from schizoaffective disorder. Psychiatric rehabilitation consists of eight main areas:▪ Psychiatric (symptom management)▪ Health and Medical (maintaining consistency of care)▪ Housing (safe environments)▪ Basic Living skills (hygiene ,meals ,safety ,planning ,chores)▪ Social (relationships ,family ,boundaries ,communications & community integration)▪ Vocational and/or Educational (coping skills , motivation)▪ Financial (personal budget)▪ Community and Legal (resources)ComplicationThe following complications are more prevalent in outpatient treatment.▪ Difficulty following medical treatment.▪ Substance use ,misuse ,abuse and addiction.▪ Serious side effects and adverse effects from long-term use of prescribedmedication ,including obesity ,types diabetes and metabolic syndrome.▪ Problems resulting from untreated or undertreated manic behavior.▪ Suicide due to mixed episode ,severe depression ,or psychosis.1.Schizoaffective disorder. [Internet]. Available from:/wiki/Schizoaffective_disorder2.American Psychiatric Association. Diagnostic and statistical Manual of Mental Disorders ,fifthedition. Arlington ,VA: American Psychiatric Association ; 2013.p.105-110.3.Schizoaffective disorder. [Internet]. Available from:/health/schizoaffective-disorder/DS008664.Schizoaffective disorder.[Internet]. Available from:https:///…../Schizoaff ective_Disorder_ Factsheet.pdf。
精神分裂症Schizophrenia2讲课文档
思维涌现(强制性思维)在无外界原因的基础上, 涌现大量思维并伴有不自主感。
病理性象征性思维 用一些普通动作或词,代表某 些特殊的,除自己外别人不能理解的意义。 如;将一根红毛线将自己和暖器片连起来,比做 知识分子和工人阶级相结合。
语词新作 用一些特殊的文字或自创符号赋予特 殊意义。如;男女放到一起称谓结婚,四代表 同学,八和红色代表李洪治。
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临床表现
意识障碍 精神运动性兴奋 精神运动性抑制 与病因有直接关系
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延迟性心因性反应 适应障碍
概念:又称创伤性应激障碍。精神创伤后数日至半 年内出现。
一般一年内恢复 少数病人持续多年不愈,成为持久性精神病态。 原因:一场性恐怖事件或灾难性事件。 患病率:一般患病率1-14%;高危人群3-58%。像复
对木僵病人要做好生命指标的观察和及时的护理。
对意志减退、退缩和淡漠的病人,要进行心理康复教育, 增加回归社会的可能。
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重复内容过多; 诊断:依据CCMD—Ⅲ过少。 鉴别诊断:要点很好。 病程及预后 治疗高效价低剂量。 增加剂量的形式较好。
第三页,共34页。
(四)神经生化病理假说
多巴胺活动过度假说 酚噻嗪类及丁酰苯类抗精神病药 物的药理作用主要是阻断多巴受体,而治疗发作性睡 病的苯丙胺是多巴胺的促动剂,当其中毒时可出现与 精神分裂症相类似的症状。如幻觉、妄想等。而多巴 阻断则精神症状消失。
第四页,共34页。
假说
酚噻嗪 阻断 多巴 促动 苯丙氨
第二十五页,共34页。
护理措施 安全和生活护理
(1)提供良好的病房环境
冲动病人单独居住
概述 鱼类分类学的概述
圆口纲: 圆口纲:Cyclostomata 七鳃鳗目 Petromyzoniformes 盲鳗目 Myxiniformes
软骨鱼纲: 软骨鱼纲: 1.板鳃亚纲 Elasmobranchii) 1.板鳃亚纲 (Elasmobranchii) Pleurotremata)(鲨形总目Selachomorpha Selachomorpha) (1)侧孔总目 (Pleurotremata)(鲨形总目Selachomorpha) 六鳃鲨目 Hexanchifomes 虎鲨目 Heterodontiformes 鲭鲨目 Isuriformes 须鲨目 Orectolobiformes 真鲨目 Carcharhiniformes 角鲨目 Squaliformes 锯鲨目 Pristiophoriformes 扁鲨目 Squatiniformes 鳐形总(Batomorpha)】 (2)下孔总目 (Hypotremata) 【鳐形总(Batomorpha)】 锯鳐目 Pristiformes 鳐形目 Rajiformes 鲼形目 Myliobatiformes 电鳐目 Torpediniformes 全头亚纲( 2.全头亚纲(Holocephali) 银鲛目
二.鱼类分类界元 列表举例
界Kingdom 门Phylum 亚门SubPhylum 亚门SubPhylum 纲class 亚纲Subclass 亚纲Subclass 总目Superorder 总目Superorder 目order 亚目Suborder 亚目Suborder 总科Superfamily( Superfamily(总科Superfamily(-idae) (科Family (-idae) 亚科Sub (亚科Sub Family (-idae) 属genus 亚属Subgenus 亚属Subgenus 种Species 亚种Subspecies 亚种Subspecies
心理学专业词汇翻译(A-B)
心理学专业词汇翻译(A-B)心理学专业词汇英语翻译(A-B)action error 动作误差action exercise 动作练习action feedback 动作反馈action form 动作形式action frame of reference 参考行动架构action group 行动群体action imitation 动作模仿action interpretation 动作解释action language 动作语言action modeling 动作示范action need 活动需要action of stereotype 刻板动作action orientation 动作定向action pattern 动作模式action potential 动作电位action principle 作用量原理action profile 行动剖析action reports 执行报告action research 行动研究action set 动作定势action space 行为空间action stability 动作稳定性action system 动作系统action tendencies 行动倾向action theory 活动说action thinking 动作思维action time 动作时间action triggered language 动作引发的语言action unit 动作单元action zone 主动区action orientedaction orientedaction specificaction timeaction 动作activate 激活activated epilepsy 诱发性癫痫activated sleep 活动性睡眠activated stateactivating system 激动系统activation center 激活中心activation energy 活化能activation index 活化指数activation level 激活水平activation of learning motivation 学习动机的激发activation pattern 激动模式activation process 激活过程activation ratio 活化比activation theory of emotion 情绪激活理论activation theory 激活理论activation synthesisactivation 激活activational effect 引发性效应activator 激活剂active adaptation 活动性适应active analysis 活动分析active analytic psychotherapy 主动分析心理治疗法active articulator 积极发音器官active attention 活动注意active avoidance 积极躲避active avoidance 主动回避active castration complex 主动阎割情结active center 活力中心active complex 活动情结active consciousness 主动意识active constraint 起作用的约束active delirium 躁狂性谵妄active directive 积极教导active electrodeactive element 主动元素active euthanasia 主动安乐死active exercise 自动运动active fantasying 主动幻想治疗active forgetting 自动遗忘active homing 主动接近active imagination 主动想象力active inhibition 主动抑制active intellect 能动的智慧active language 主动语言active learning 积极学习active living process 能动的生命过程active negativism 主动抗拒性active orientation 主动取向active participation 主动参与active potency 主动潜能active principle 主动原则active public 积极的公众active qi gong 动气功active reaction 主动反应active reason 能动的理性active recall 主动回忆active region 作用区active responding 积极反应active role 积极任务active schedule 活动一览表active search theory 主动探索理论active set 作用集active site 活性部位active sleep theory 主动睡眠理论active society 积极的社会active speech 主动言语active stimulus 有效刺激active testimony 主动作证主动作证active therapy 主动疗法active transfer 主动传递active type 活泼型active variable 主动变量active vocabulary 主动词汇active passiveactive resistiveactive 活动性activeness 主观能动性activism 能动性activist point of view 能动主义观点activist psychology 能动心理学activist 行为能动论者activity analysis problem 行动分析问题activity analysis 活动分析activity cage 活动笼activity concept 活动概念activity curriculum 活动课程activity cycle 活动周期activity dimension 活动维度activity drive 活动驱力activity factor 活动因素activity inventory 活动记录activity learning 活动学习activity level method 动量法activity level 活动水平activity log 活动日志activity method of teaching 活动教学法activity need 活动需求activity of personalityactivity optimization 活动方式最佳化activity pattern 活动模式activity quotient 活动商数activity rating 活动评等activity sampling 活动抽样activity system 活动系统activity theory of aging 老年活动论activity theory of learning 学习活动论activity theory 活动论activity therapy 活动疗法activity dependentactivity groupactivity interviewactivity playactivity wheelactivity wheelactivity 活动actograhy 动作记录法actograph 动作记录器actometer 活动度测量计actor observeractor 男演员actor 行事者actual anxiety 真实性焦虑actual being 实在actual conflict 真实冲突actual entity 现实实有actual frequency 实际频率actual hour 实际时间actual leader 实际领袖actual life 实际寿命actual limit 实际限度actual measurement 真实量度actual mechanical process 实际操作过程actual neurosis 真实神经症actual number 实际数actual numerical value 实际数值actual parameter 实际参数actual population 实际人口actual power 有效功率actual range 实际范围actual rate of growth 实际增长率actual self 现实我actual survey work 实际调查工作actual survey 实际调查actual time 实际时间actual value 实际值actual working rate 实际劳动率actual 真实的actualism 现实主义actualist 现实论者actuality philosophy 现实哲学actuality 现实性actualization 现实化actualized reason 实现了的理性actualizing therapy 实现治疗法actuarial prediction 统计预测actuation 开动actuator 执行机构acuity 敏度aculeus 皮刺acumen 敏锐acumeter 听觉计acupuncture anesthesia 针刺麻醉acupuncture 针灸术acute alcoholic hallucinosis 急性酒精幻觉症acute alcoholic intoxication 急性酒精中毒acute alcoholism 急性酒精中毒acute anxiety 急性焦虑acute brain syndrome 急性脑综合症acute confusional state 急性困惑状态acute confusional 急性精神错乱acute dementia 急性痴呆acute depression 急性抑郁症acute disseminated encephalomyelitis 急性感染后脑脊髓炎acute distress syndrome 急性忧伤综合症acute effect 急性效应acuteexperiment 急性实验acute fatigue 急性疲劳acute hallucinatory mania 急性幻觉性躁狂acute hallucinatory paranoia 急性幻觉性妄想狂acute hallucinosis 急性幻觉症acute hunger state 急性饥饿状态acute intoxication 急性中毒acute mania 急性躁狂acute paranoia 急性偏执狂acute postinfection encephalom yelitis 急性感染后脑脊髓炎acute psychogenic reaction 急性心因性反应acute psychosis 急性精神症acute psychotic episodeacute schizophrenia 急性精神分裂症acute schizophrenic episode 急性精神分裂症性插话acute situation reaction 急性情境反应acute stress reaction 急性压力反应acute 急性的acyanoblepsia 蓝色盲ad absurd reasoning 归谬推理ad hoc hypothesis 特设性假设ad hoc rule 特定规则ad hoc way 特定方式ad hoc 特别AD 平均差adage 谚语Adami sAdams Stokesadaptability test 适应性测验adaptability 适应性adaptability 顺应性adaptable 适应性强的adaptation character 适应特性adaptation level 适应水平adaptation level theory 适应水平论adaptation norm 适应规范adaptation reaction 适应性反应adaptation response 适应性反应adaptation syndrome 适应综合症adaptation theory 适应论适应论adaptation time 适应时间adaptation to darkness 暗适应adaptation to end 适应目的adaptation to imprisonment 监狱适应adaptation tolerance 适应耐性adaptation trial 适应尝试adaptation 适应adapted culture 适应性文化adapted information 适应性知识adapted 适应的adapter molecule 衔接分子adapter 转接器adaption 适应adaptive act 适应活动Adaptive Behavior Scale 适应行为量表adaptive behavior 适应行为adaptive capacity 适应能力adaptive character 适应特性adaptive coloration 适应色adaptive compensation 适应补偿adaptive conformity 适应性从众adaptive control 适应性控制adaptive convergence 趋同适应adaptive crisis 适应危机adaptive decision makingadaptive delinquency 适应型犯罪adaptive differentiationadaptive dispersion 适应分散adaptive evolution 适应进化adaptive facultyadaptive feedback control 适应性反馈控制adaptive flexibility 适应的灵活性adaptive form 适应类型adaptive mechanism 顺应机制adaptive norm 适应规范adaptive optimal control 最优适应adaptive optimization 适应最优化adaptive peak 适应高峰adaptive phase 适应阶段adaptive process 适应过程adaptive program 适应性程adaptive reaction 适应反应adaptive regression 适应退化adaptive sampling 适应性抽样adaptive selection 适应选择adaptive strategy 适应策略adaptive strategy 因应策略adaptive subsystem 顺应子系统adaptive testing 适应性测验adaptive time 适应时间adaptive training 适应训练adaptive value 适应值adaptive 适应的adaptivity 适应性adaptometer 适应测量器ADC 线索的习得明显性ADD 注意缺失紊乱add pulse 加法脉冲addaverter 方法转换器addict 成瘾者addiction research 反毒瘾研究addiction 成瘾addiction 嗜好addictive behavior 成瘾行为addictive personality 毒瘾性格addictive personality6 成瘾人格adding mechanism 加法机制adding model 总和论Addison s additament 附加物addition mixture 加法混色addition of class 类的加法addition of probabilities 概率的加算addition test 加算测验addition 加法additional pollution 增添污染additive color mixture 相加混色additive effect 累加效应additive factors method 附加因素法additive factors 附加因素additive mixture 相加混色additive model 相加模型additive operation 加法运算additive process 加法过程additive property of chi square additive property 可加性additive reaction 加成反应additive scale 相加量表additive 附加的additivity of means 平均数可加性additivity of probability 概率可加性additivity of X 2additivity 可加性adduce 引证adduction 内受作用ADEM 急性感染后脑脊髓炎adenalgia 腺痛adenasthenia 腺机能衰弱adendritic无树突的adenectomy 腺切除术adenectopia 腺异位adenitis 腺炎adenocarcinoma 腺癌adenocele 腺囊肿adenohypersthenia 腺机能亢进adenohypophysis 腺性垂体adenoma 腺瘤adenoncus 腺肿大adenoneural 腺神经的adenopathy 腺病adenosine diphosphate 二磷酸腺苷adenosine triphosphate 腺苷三磷酸adenosine 腺苷adenosis 腺病adequacy 适合性adequate cause 充分动因adequate response 适当反应adequate sample 适足样本adequate stimulus 适度刺激adequate variability 适应变异性adequate variation 适应变异ADH 抗利尿激素adiaphanous 不透明的adiaphorism 中庸adience 接近趋向adient behavior 趋近行为adient response 趋近反应adipose cell 脂肪细胞adipose gland 脂腺adipose tissue 脂肪组织adiposis 肥胖症adipsia 不渴症adipsia 失饮症adjacency 接近性adjacent association 邻近联想Adjective Check List 形容词检核表adjective check list 形容词检选表adjective gland 附加腺adjourning 中止阶段adjunctive behavior 附属行为adjunctive program 补充作业adjunctive 附属性质adjust 调整adjustable mask 可调屏幕adjusted rate 修正率adjusted solution 调整溶液adjustment disorder 适应性疾病adjustment failure 适应失败adjustment inventory 适应量表adjustment level 顺应水平adjustment mechanism 调整机制adjustment mechanism 适应方式adjustment method 调整法adjustment phase 调整期adjustment procedure 适应法adjustment process 调整过程adjustment reaction 适应反应adjustment system 调整系统adjustment time 调整时间adjustment to school 学校适应adjustment 调整adjustment 适应adjustor 调整器adjustor 适应器顺应器adjutant therapy 辅助治疗法Adler sAdlerian groups 阿德勒团体Adlerian psychology 阿德勒心理学Adlerian psychotherapy 阿德勒心理治疗法adlumidine 紫罂粟次碱adlumine 紫罂粟碱admeasure 分配adminicle 辅助administer管理administration behavior 管理行为administration by different levels 分级管理administration function of test 测验的管理功能administration route 处理途径administration section 管理部门administration 管理administration 行政Administrative Aptitude Test 行政职业能力测验administrative channel 行政渠道administrative control 行政控制administrative function of test 测验的管理功能administrative man 管理人administrative organization 管理机构administrative organization 行政组织administrative procedure 管理程序administrative reliability 施测信度administrative staff 管理人员administrative unit 行政单位administrator 管理人员admiration 羡慕admissibility 容许性admissible action 容许行动admissible condition 容许条件admissible control 容许控制admissible error 容许误差admissible hypothesis 容许假设admissible mark 及格分数admissible mark 容许符号admissible parameter 容许参数admissible test 容许检定admission age 入学年龄admission criteria 录取标准admission qualification 入学资格admission requirement 入学标准admission 容许进入admit 容许admittance 接纳admonition 告诫adnerval 近神经的adolescence moratorium 青年期延缓adolescence 青年期adolescent age 青年期adolescent behavior 青少年行为adolescent characteristics 青年期特征adolescent crisis 青年期危机adolescent culture 青年文化adolescent dementia 青春期痴呆adolescent depression 青年期抑郁adolescent development 青少年发展adolescent education 青少年教育adolescent growth spurt 青少年发育急速期adolescent identity formation 青年期同一性形成adolescent insanity 青少年期精神错乱adolescent needs 青年期需要adolescent problems 青少年问题adolescent psychiatry 青春期精神病学adolescent psychology 青少年心理学adolescent society 青年社会adolescent subculture 青年次文化adolescent 青少年adopt 采用adopted child 收养儿童adoption of answers 选答法adoption 领养adoptive parents养父母adoptive studies 收养研究ADP 二磷酸腺苷adrenal capsule 肾上腺adrenal cortex 副肾皮质adrenal cortex 肾上腺皮质adrenal gland 副肾adrenal gland 肾上腺adrenal insufficiency 肾上腺机能不全adrenal medulla 副上肾髓质adrenalectomy 肾上腺切除术adrenalinaemia 肾上腺素血症adrenaline 肾上腺素adrenalinogenesis 肾上腺素生成adrenalinuria 肾上腺素尿adrenalismus 肾上腺中毒adrenalitis 肾上腺炎adrenalone 肾上腺酮adrenalopathy 肾上腺病adrenalotropic 促肾上腺的adrenergic blocking drug 肾上腺素能阻断剂adrenergic fiber 肾上腺素纤维adrenergic receptor 肾上腺素受体adrenergic substance 肾上腺素能物质adrenergic 肾上腺素能的adrenergics 肾上腺素能物质adrenitis 肾上腺炎adrenoceptor 肾上腺素能受体adrenochrome 肾上腺素红adrenocortical hormone 肾上腺皮质激素adrenocorticohyperplasia 肾上腺皮质增生adrenocorticomimetic 类肾上腺皮质激素的adrenocorticotrophic hormone 肾上腺皮质促进激素adrenocorticotropin 促肾上腺皮质激素adrenogenital syndrome 肾上腺综合症adrenogenous 肾上腺元的adrenoglomerulotropin 促醛甾酮激素adrenogram 肾上腺X线照片adrenolutin 肾上腺黄素adrenolytic 抑肾上腺作用的adrenomedullotropic 促肾上腺髓质的adrenomegaly 肾上腺肿大adrenopathy 肾上腺病adrenopause 肾上腺机能停滞adrenoprival 肾上腺缺乏的adrenoreceptor 肾上腺素能受体adrenostatic 抑肾上腺作用的adrenosterone 肾上腺雄甾酮adrenotoxin 肾上腺毒素adrenotropic 促肾上腺的adrenotropin 促肾上腺皮质激素adrenoxidase 肾上腺氧化酶Adrian principle 全或无律adromia 肌神经传导缺失ADS 抗利尿物质adterminal 向末端的adtorsion 两眼内旋adualism 非二无论adult age 成人期adult basic education 成人基础教育Adult Basic Learning Examination 成人基本学习考试adult development 成年发展adult disease 成人病adult education 成人教育adult intelligence 成年智力adult learning 成年学习adult period 成年期adult physical fitness test 成人体能测验adult psychology 成年心理学adult socialization 成人社会化adult stage 成年期adult training 成人训练adult gerontologicaladult 成人adulthood 成年期adultomorphism 拟成人论advance estimate 事前估计值advance evaluation 事前评估advance organizer 先导组织者advance potential 超前势advance 推进advanced character 进步特征advanced control 先行控制advanced generation 后生世代advanced growth 增进生长advanced placement 跳级advancement of knowledge 增进知识advancement 促进advancing color 近色advancing complexity 进化综合advancing difference 进差advantage by illness 因病得益advantage of sampling 抽样的优点advantage 有利条件有利条件advent behavior 趋近行为advent response 趋近反应advent 出现adventitious circumstances 偶然情形adventitious deaf 偶发性耳聋adventitious deafness 偶发性聋adventitious reinforcement 偶然强化adventure playground 儿童游乐场adventure 冒险adventurer 冒险家adventuresome 爱冒险的adventuress 女冒险家adventurism 冒险主义adventurist 冒险主义者adventuritic 冒险主义的adventurous thinking 喜欢冒险的思考adventurous 喜欢冒险的adverse movement 反向运动adversity 逆境advertent 注意的advertisement project 广告设计advertisement psychology 广告心理学advertising campaign 广告运作advertising effectiveness measurement 广告效果的测定advertising media 广告媒体advertising psychology 广告心理学advertising research 广告研究advertising 广告advice note 通知单advice 忠告advise 劝告advisement 劝告advisor 顾问advocacy advertising 辨护广告advocacy 支持adynamia 动力缺乏adynamic stage 无效期AE 后效AEC 线索的习得等同性aegis 保护aelurophobia 恐猫症aerasthenia 飞行员精神衰弱aerial perspective 空间透视aero astheniaaero spaceaerobic metabolism 需氧代谢aerobiology 大气生物学aerodynamic 空气动力学aerology 高空气象学aeromedicine 航空医学aeronautical and astronautical psychology 航空和航天心理学aeroneurosis 飞行员神经机能病aeropathy 航空病aeropathy 气压病aerophagia 咽气症咽气症aerophobia 气流恐怖症aeroscepsy 测空特殊感觉aeroscepsy 声嗅感觉aeroscope 空气检查器空气检查器Aerospace Medical Research Laboratory 太空医学研究实验室aerospace medicine 宇宙医学aerospace noise 宇宙航空噪声aerospace personnel 宇航人员aerospace psychology 宇宙心理学aerostatic 空中平衡的aerostatics 空气静力学Aero Medical Acceleration Laboratory 航空医学加速实验室Aero Medical Equipment Laboratory 航空医学设备实验室aeruginous 蓝绿色aesthesia 感觉aesthesiology 感觉学aesthesiometer 触觉计aesthesis 感觉aesthete 审美家aesthetic activity 审美活动aesthetic apperception 审美统觉aesthetic appreciation 审美aesthetic association 审美联想aesthetic attitude 审美态度aesthetic concepts 审美概念aesthetic contrast 审美性对比aesthetic education 美育aesthetic emotion 审美感情aesthetic emotivism 美学感情主义aesthetic feeling 美感aesthetic ideal 审美理想aesthetic impression 美感印象aesthetic intention 审美意向aesthetic intuitionism 美感直觉说aesthetic judgment 审美判断aesthetic mental set 审美心理定势aesthetic need 爱美需要aesthetic pedagogy 美育学aesthetic perception 美的知觉aesthetic pleasure 审美享受aesthetic psychology 审美心理学aesthetic qualities 美学的特征aesthetic sensibility 美感aesthetic sociology 艺术社会学aesthetic taste 审美趣味aesthetic value 审美价值aesthetical idealism 审美唯心主义aesthetical mental set 审美心理定势aesthetical standard 审美标准aesthetician 美学家aestheticism 审美感aesthetics 美学aestho physiologyaestivation 夏眠aether 乙醚aetiology 病源学病源学AFD 儿affair 事情affect display 情感展示affect structure 情感结构affect fantasy情感性幻想affect hunger情感性饥饿affect 情感affectation 装模作样affection less character 情感缺乏性格affection need 情感需求affection 情感affectional attachment 情感性依附affectional category 情感范畴affectional drive 情感驱力affectional tie 情感纽带affectionless 无情的affectionlessness 无情affective activity 情感活动affective ambivalence 情感矛盾affective amnesia 情感型失忆症affective arousal theory 情感促动论affective association 情感联想affective behavior 情感行为affective blunting 情感迟钝affective categorizing 情感概念化affective characteristics 情感特征Affective Commitment Scale 感情承诺量表affective commitment 感情承诺affective communication 情感传达affective component 情感成份affective content 情感内容affective control 情感控制affective depression 情感性抑郁症affective deterioration 情感衰退affective development 情感发展affective disorder 情感障碍affective display 情感展示affective disturbance 情感障碍affective domain 情感范畴affective education 情感教育affective epilepsy 情感性癫痫affective experience 情感经验affective feeble mindedness情感型智弱affective fixation 情感固着affective flattening 情感冷淡affective fragility 情感脆弱affective impulse 情感冲动affective infantility 情感幼稚affective insanity 情感性精神病affective interaction 情感交流affective logic 情感逻辑affective meaning systemaffective melancholia 情affective neuron 感受神经affective panic reactionaffective profundity 情感affective psychosis 情感affective ratio 情感比率affective reaction typeaffective reaction 情感性affective response 情感反affective schizophreniaaffective separation 情感affective state 情感状态affective stupor 情感性木affective suggestion 情感affective syndrome 情感性affective thinking 情感性affective tolerance 情感affective tone 情调affective conativeaffective 情感的affectivity 情感性affectomotor 情感运动的afferent behavior 内导行为afferent bipolar cell 传入两极细胞afferent fibers 传入纤维afferent impulse 传入冲动afferent interaction 内导相互作用afferent nerve 传入神经afferent neuron 传入神经元afferent pathway 传入通路afferent phase 传入期afferent stimulus interaction 内导刺激相互作用afferent 传入的afferentiation 传入刺激作用affiliated drive 附属内驱力affiliation motive 亲和动机affiliation need 交往需要affiliation need 亲和需要affiliation orientedaffiliation 合群affiliation 合群倾向affinitive behavior 亲和行为affinitive drive 亲和驱力affinitive motivation 亲和动机affinitive motive 亲和动机affinity 亲和力affirm 肯定affirmation 肯定affirmative action programs 赞助性行动计划affirmative and negative law 肯定否定定律affirmative judgment 肯定判断affirmative proposition 肯定命题affirming the antecedent 肯定前项affirming the consequent 肯定后项afflatus 神感afflux of stimulus 刺激传入afflux 流入AFG 儿afraid 害怕after effect time 后作用时间after effect 后效後效after image 后像after actionafter brainafter currentafter depolarization后去极化after dischargeafter effectafter effectafter hyperpolarizationafter imageafter impressionafter lifeafter loadingafter movementafter nystagmusafter perceptionafter potentialafter sensationafter sensationafter soundafter tasteafter visionafterbody 后部aftercare interview 调护面谈aftercare 病后调护病後调护afterhearing 余听觉afterheat 余热afterhyperpolarization 后超极化afterimage 后像afterripening 后热aftersensation 后觉aftertest 后测afunction 机能缺失aganglionosis 神经节细胞缺乏症agastria 无胃畸形age at death 死亡年龄age at withdrawal 退休年龄age characteristics 年龄特征age class 年龄级age composition 年龄构成age constraints 年龄约束age differences 年龄差异age distribution 年龄分布age equivalent 年龄当量age grade distribution 年龄年级分配age grade position 年龄年级位置age grade scaling 年龄年级量表age grading 年龄分级age group 年龄组age heaping 年龄积算age immunity 年龄免疫性age indication 年龄指数age involution 年龄退缩age migration 年龄侵移age morphology 年龄形态学age norm 年龄常模age of belief 信仰的年代age of exploration 探索的年龄age of first crime 始犯年龄age of reason 理性年代age of reasoning 推理的年龄age of sucking 哺乳期age pattern analysis 年龄分布状况分析age psychology 年龄心理学age pyramid 年龄金字塔age pyramid 年龄锥体age qualifying for an old ageage ratio 年龄比age regression 返童记忆age replacement 年龄置换age scale 年龄量表age score 年龄分数age specific natality rate 特定年龄出生率age stratification 年龄分层age structure 年龄构成age variability scale 年龄差异量表age variability unit 年龄差异单位age variation 年龄变异age appropriateage gradeage gradeage limitage maritalage matesage performanceage progressage sexage specificage specificage specific maritalage 年龄aged family 老年家庭aged tendency of population 人口老龄化aged 老年人ageing 衰老ageism 年龄主义ageless 不会老的agency 能量agenesis of corpus callus 胼胝体发育不全agenesis 发育不全agenitalismus 生殖腺机能缺乏agent 动因agerasia 容颜不老ageusia 失味觉症ageusic aphasia 味觉性失语agglomerate 聚集agglomeration 粘结agglomerative 聚集的agglutinating analogy 粘着类推agglutination reaction 凝集反应agglutination 集聚agglutinative index 粘着指数aggregate adjustment 综合调整aggregate analysis 综合分析aggregate balancing 综合平衡aggregate concept 综合概念aggregate data 综合数据aggregate efficiency 总效率aggregate feeling 集合情感aggregate idea 集体观念aggregate model 总体模式aggregate of individuals 个人的集合aggregate relation 总量关系aggregate score 总分aggregate variable 综合变量aggregate valueaggregate 集群aggregate 整合aggregation pheromone 集合体现象aggregation theory 集合功能论aggregation 集合体aggregation 群集aggregative index 综合指数aggregative indicator 综合指标aggregative method 综合法aggregative model 综合模型aggregative planning 综合计划aggregative relationship 群集关系aggression turned inward 内向攻击aggression frustrationaggression 攻击aggression 侵犯aggressive attitude 侵犯态度Aggressive Behavior 攻击行为攻击行为aggressive behavior 攻击行为aggressive catharsis 攻击发泄aggressive drive 攻击驱力aggressive impulse 攻击冲动aggressive instinct 攻击本能aggressive mechanism of convict 罪犯攻击机制aggressive mechanism 攻击机制aggressive mimicry 攻击拟态aggressiveness type 侵占型aggressiveness 攻击性aggressiveness 侵略性aggressivity 攻击性Aging & Mental Health 衰老与心理健康aging alienation 衰老性自我疏外aging compensation decrement 衰老性补偿性减量aging decrement 衰老性减量aging DNA damage 衰老性脱氧核糖核酸毁损aging intellectual deterioration 衰老性智力衰退aging irreversible decrement 衰老性不可逆减量aging memory decline 衰老性记忆下降aging of labor force 劳动力的老龄化aging of population 人口的老年化aging period 老年期aging population 老年人口aging psychology 老年心理学aging regression behavior 衰老性退缩行为aging sexual behavior 衰老性性行为aging 老化agitate dementia 激越性痴呆agitate 焦急不安agitated crowd 骚动的群众agitated depression 激动性抑郁症agitated mania 激动躁狂症agitated melancholia 激动性忧郁agitation 激动agitographia 急噪性错写症agitolalia 急语症agitophasia 过速失语症agitophasia 躁急错语症aglaucopsia 绿色盲aglutition 吞咽不能aglycemia 血糖缺乏agnate 男方亲属agnea 失认agnogenic 病因不明的agnosia 认识不能agnosia 失认症agnosic 失认的agnosticism 不可知论agnosticrealism 不可知的实在论agonaphobia 恋旷野癖agonist 催动性agonist 主动肌agonistic behavior 争胜性行为agonize 折磨agony 剧痛agoraphobia 恐空旷症agrammatism 语法缺失agrammatismus 语法缺失agraphia 失写症agree scale 同意量表agree 同意agreeableness 随和性agricultural psychologyagriothymia 狂躁情感agromania 独处狂agromania 隐居癖agrypnia 失眠agrypnocoma 醒态昏迷agyria 无脑回畸型aha experience 顿悟经验ahedonia 性快感缺失ahistorical approach 非历史方法ahypnia 失眠症ahypnosis 失眠症AI 人工智能AIAMA Principle AIAMAAichhore therapeutic experiment 艾希哈尔治疗实验aichmophobia 恐尖器症aid to learning 学习工具aid 助手aided recallaiding of tracking 追踪的辅助aids to object teaching 直观教具ailment 疾病ailurophile 嗜猫癖ailurophobia 恐猫症AIM (anticipation invigorationaim inhibited drive 目标抑制驱力aim inhibition 目标抑制aim transference 目标转移aim 目标aiming test 瞄准测验aims of education 教育目的Ainsworth strange situation technique 艾氏陌生情景技术air bag 气袋air borne sensor 空气传感器air borne 空气传播air cavity 气腔air chamber 气室气室air cleaner 空气净化装置air condition 空气调节air conditioner 气温调节装置air conditioning 气温调节air conduction 气导气导air force personnel 空军人员air pillow 空气枕头air pollution syndrome 空气污染综合症air pollution 空气污染air pressure and altitude 气压与高度air sickness 空晕病air temperature 气温air traffic accident 空运事故air traffic control 空中交通管制air velocity 风速air washer 空气洗洁器air proofair sicknessair speedaircraft disease 航空病aircraft pilots 飞机驾驶员airflow 气流airplane 飞机airsick 晕机的airsickness 航空病akatama 慢性周围神经炎akatamathesia 理解不能akatanoesis 自我理解不能akathisia 静坐不能akathisia 失静症Akerlund deformity 阿克隆德变形akinesia amnesica 遗忘性运动不能akinesia 运动不能akinesis 失动症akinesthesia 运动感觉缺失akinetic apraxia 运动性失用症akinetic mania 运动躁狂症akinetic mutismus 不动不语症akinetic mutismus 运动不能性缄默akoasm 耳鸣akoasm 幻听akoria 不饱症Aktpsychologie 意向心理学Akureyri disease 良性肌痛性脑脊髓炎AL 适应水平alalia cophosis 聋哑症alalia 构音不能alarm bell 警铃alarm call 警报呼叫alarm clock 闹钟alarm pheromone 警告外激素alarm reaction 警觉反应alarm reaction stage 警觉反应阶段alarm response 警觉反应alarm signal 警报信号alarm 警报alarming devices 警报装置alarming 使人惊恐Albarran salbedo perception 反照知觉albedo retina 视网膜水肿albedo 反照率Albert salbinism 白化病Albinus sAlbrecht sAlbright salbuginea oculi 巩膜albuginea 白膜albuminous body 蛋白体albuminuria amaurosis 蛋白尿性黑蒙albuminurophobia 蛋白尿恐怖症albuminurophobia 恐蛋白尿症alcohol abuse 酒精饮料滥用alcohol addiction 酗酒瘾alcohol dependence 酒精依赖alcohol intoxication 酒精中毒酒精中毒alcohol paranoid state 酗酒妄想狂状态alcohol 酒精alcoholic amnesia disorder 酒精性失忆症alcoholic brain syndrome 酒精中毒脑综合症alcoholic delirium 酒精中毒性谵妄alcoholic dementia 酒毒性痴呆alcoholic deterioration 酒精中毒性衰退alcoholic hallucinationalcoholic hallucinosis 酒精中毒性幻觉症alcoholic insanity 酒精中毒性精神病alcoholic jealousy 酒精性嫉妒alcoholic mania 酒狂alcoholic paralysis 酒精中毒性麻痹alcoholic paranoid 酒精中毒性妄想狂alcoholic poisoning 酒精中毒alcoholic polyneuropathy 酒精中毒性多元神经症alcoholic psychosis 酒精性精神病Alcoholics Anonymous 慝名戒毒会alcoholism 酒精中毒alcoholism 酒瘾alcoholization 酒精疗法alcoholizing 醇化alcoholomania 嗜酒癖alcoholophilia 酒癖Alderfer saldosterone 醛固酮alert 警觉alertness 警觉状态alexia without agraphia 非失写的失读症alexia 失读症alexipharmic 解毒的alexithymia 述情障碍aleydigism 睾丸间介细胞机能缺失alganesthesia 痛觉缺失algebra addition 代数加法algebra of logic 逻辑代数algebra of proposition 命题代数algebra of sets 集代数algebra 代数algebraic addition formula 代数加法公式algebraic analysis 代数分析algebraic body 代数体algebraic computer 代数计算机algebraic deviation 代数偏差值algebraic expression 代数表达式algebraic linguistics 代数语言学algebraic operation 代数运算algebraic semantics 代数语义学algebraist 代数学家algedonic 欣快痛觉algesia 痛觉algesichronometer 痛觉时间计algesimetry 痛觉测定法algesiometer 痛觉计algesireceptor 痛感受器algesthesia 痛觉algetic meter 痛觉计algetic 痛的alginuresis 痛性排尿algogenesis 痛产生algoglandular 痛性腺活动的ALGOL 计算机算法语言algolagnia 施虐色情狂algometabolic 痛性代谢改变的algometer 痛觉计algometry 痛觉测验法algomotor 痛性运动的algomuscular 痛性肌活动的algophilia 嗜痛癖algophobia 恐痛症algophobia 痛恐怖症algopsychalia 悲痛性抑郁病algopsychalia 精神性头痛algorism instruction 算法教学algorism 十进位计算法algorism 算法论algorithm instruction 算法教学algorithm 算法algorithmic language 算法语言algorithmic model 算法模式algorithmic notation 算法表示法algorithms 算法式algovascular 痛性血管活动的alienating need dispositionalienation coefficient 相疏系数alienation in work 劳动异化alienation of self consciousness 自我意识障碍alienation 疏离alienism 精神错乱alienist 精神病学家aliment 食物alimentary reflex 唾液反射alimentation 营养法alimentative instinct 求食本能alimentative reflex 食物反射alimentology 营养学alimentotherapy 营养疗法alkalescence 弱碱性alkalimeter 碱定量器alkalimetry 碱定量法alkaline reaction 碱性反应alkalinity 碱度alkaloid 生物碱alkalometry 生物碱剂量规定Alkalosis 阿卡洛斯体质alkalosis 碱中毒all possible regression procedure 所有可能回归法all channelall or noneall or noneall or nothing。
02讲-生物的多样性及其保护1
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4、繁殖方式
• 细胞增大DNA复制 细胞增大DNA DNA复制 • 横隔形成 • 细胞分成两个DNA 细胞分成两个DNA 分别进入子细胞 • 细胞分离
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5、分类
营养类型 光能自养型 光能异氧型 化能自养型 化能异氧型 能源 光 光 化学能 化学能 碳源 无机物 有机物 无机物 有机物
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细菌的鉴别染色法
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2.3 非细胞型生物—病毒 非细胞型生物—
♪ 1、病毒的概念 、 ♪ 病毒是一类既具有化学大分子属性和生物体 的基本特征, 的基本特征,又具有细胞外感染性颗粒和细 胞内的繁殖性基因形式的十分独特的生物类 群。 ♪ 特点:个体极小;不具细胞结构;只有一种 特点:个体极小;不具细胞结构; 核酸类型;严格活细胞内寄生; 核酸类型;严格活细胞内寄生;复制的方式 繁殖;对抗生素不敏感。 繁殖;对抗生素不敏感。
教学平台的使用
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作 业
♪ 谈谈你对生命科学的认识和感兴趣的领域 ♪ 要求: 要求:
– – – – – – 不少于2000字 字 不少于 电子版, 电子版,提交到网上或交纸版 写出自己的真实感受, 写出自己的真实感受,不得抄袭 对参考文献要引用 12月1日之前交 月 日之前交 占最后考核的20-30% 占最后考核的
♪ 自然分类:按照进化上的亲缘关系进行分类, 自然分类:按照进化上的亲缘关系进行分类, 区分亲缘关系远近的依据主要是生物体的外部 形态结构。 形态结构。
寄生虫单词
《人体寄生虫学》外文、中文名词对照A.castellanii卡氏棘阿米巴Aancylostoma caninum 犬钩口线虫Acanthamoeba 棘阿米巴属acanthor 棘头蚴Acari 螨亚纲(蜱螨亚纲)Acariformes 真螨目accidental parasite 偶然寄生虫acetabulum 腹吸盘acquired immunity 获得性免疫adult 成虫Aedes aegypti 埃及伊蚊Aedes albopictus白纹伊蚊African trypanosomiasis 非洲锥虫病agglutinin 凝集素AIDS艾滋病albendazole 阿苯达唑(丙硫咪唑)Aldrichina grahami巨尾阿丽蝇allethrin 丙烯菊酯Alocinma longicornis 长角涵螺alternation of generations 世代交替alveolar hydatid cyst 泡球蚴amastigote 无鞭毛体amebae阿米巴American trypanosomiasis 美洲锥虫病aminoquinoline 氨基喹啉amoeba pores 阿米巴穿孔素amoebic colitis 阿米巴性结肠炎amoebic dysentery 阿米巴痢疾amoebic keratitis (AK) 阿米巴性角膜炎amoebic liver abscess 阿米巴肝脓肿amoeboma 阿米巴肿anal swab 肛门拭子法Ancylostoma braziliense 巴西钩口线虫Ancylostoma ceylanicum锡兰钩口线虫Ancylostoma duodenale十二指肠钩口线虫anemia 贫血Angiostrongylus cantonensi s 广州管圆线虫anisakiasis 异尖线虫病Anisakis 异尖线虫Anopheles anthropophagus嗜人按蚊Anopheles dirus大劣按蚊Anopheles minimus 微小按蚊Anopheles sinensis 中华按蚊Anoplura 虱目antenna 触角anticoagulin 抗血凝素antigen determinant 抗原决定簇antigen disguise 抗原伪装antigenic variation 抗原变异anti-idiotypic antibody 抗独特型抗体apical prominence 顶突apoptosis 细胞凋亡Arachnida 蛛形纲Araneae 蜘蛛亚纲arbo-disease 虫媒病Argasidae 软蜱科artemether 蒿甲醚artemisinin (quinghaosu)青蒿素artesunate青蒿琥酯ascariasis 蛔虫病Ascaris lumbricoides 似蚓蛔线虫ascaroside 蛔甙层asexual generation 无性生殖Balantidiidae 小袋科Balantidium coli结肠小袋纤毛虫basal body 基体basal lamella 基质膜basal plasmamembrane 基质膜basement layer 基层basoquin 氨酚喹阿莫地喹baytex 倍硫磷bed bug 臭虫bentonite flocculation test,BFT 皂土絮状试验binominal system 二名制biological transmission 生物性传播bithionol 硫双二氯酚Bithynia fuchsianus 赤豆螺(傅氏豆螺)biting midge 蠓black fly 蚋(黑蝇)bladderworm 囊虫Blastocystidea 芽囊原虫纲Blastocystis 芽囊原虫属Blastocystis hominis 人芽囊原虫blastocystosis hominis 人芽囊原虫病Blattaria 蜚蠊目Blattella germanica德国小蠊blephearoplast 毛基体Boettcherisca peregrina棕尾别麻蝇Boophilus microplus微小牛蜱Borrelia burgdorferi伯氏包柔氏螺旋体Borrelia latyshevyi拉氏包柔氏螺旋体Borrelia persica波氏包柔氏螺旋体Borrelia recurrentis 回归热包柔氏螺旋体bothrium 沟槽bradysporozoites,BS 迟发型子孢子。
Schizophrenia Definition, treatment & therapy
Dementia (Loss of Mind) Praecox (Early, Premature) Kraepelin
– Categorization & Early Onset
Eugen Bleuler
– Termed “Schizophrenia” – Associative Splitting
– Prolonged motor immobility states that alternate with periods of excitability
• Paranoid schizophrenia involves the presence of prominent delusions including persecution and grandiosity • Undifferentiated schizophrenia and residual schizophrenia
Paranoid Type Disorganized Type Catatonic Type Undifferentiated Type Residual Type
Have Had One Episode Now Mostly Symptom Free
Once a Schizophrenic, Always a Schizophrenic?
– Absence of Sensory Stimulation – Involve Any of the Senses
Examples
– Auditory -- Voices (70%) – Visual -- Seeing Things (25%) – Tactile -- Crawling Sensation
• Hallucinations are commonly auditory
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Delusions:
Strange beliefs that don’t make sense or cannot possibly be true
Serious misrepresentations of reality Examples include delusions of grandeur (you think you are very, very important or famous) or persecution (you think people are plotting to hurt you)
Family
The
role of psychological factors
Psychological factors play small role in producing schizophrenia
Cecilia:
67 years old José: 32 years old
Schizophrenia
vs. psychosis
Psychosis – Broad term referring to hallucinations and/or delusions; in general, a loss of touch with reality Schizophrenia – A type of psychosis with disturbed thought, language, and behavior
Hallucinations: 5 types (can involve all senses) but auditory and visual are most common
Auditory: hearing voices that aren’t there Visual: seeing things that aren’t there Other hallucinations can involve smelling (olfactory), tasting (gustatory), or feeling (tactile) things that aren’t there The nature of auditory and visual hallucinations – Findings from Single Photo Emission Computed Tomography (SPECT) studies show that Broca’s area (involved in speaking) is most active when people have auditory hallucinations, not Wernicke’s area (involved in understanding language). So, person may be hearing his own thoughts or voices and can’t tell the difference.
Onset and prevalence of schizophrenia worldwide
Schizophrenia Is generally chronic
About 0.2% to 1.5% (or about 1% population) Usually develops in early adulthood, but can emerge at any time
More
information about schizophrenia /szfacts.htm
The
Negative Symptoms: Normal behaviors that are absent or are insufficient
Emotional/social withdrawal – the person may try to
avoid talking with others. In conversation, he or she may appear bored, uninterested or cold, or avoid eye contact. Alogia (or poverty of thought/speech) - Poor communication with others. Often, they won’t speak unless spoken to directly. Avolition (or apathy) – Loss of interest in usual activities; low energy Anhedonia – Lack of pleasure, or indifference to pleasurable activities Affective flattening – Have few facial expressions or speak in monotonous voice, but may still feel emotion
Gender differences in onset of schizophrenia in a sample of 470 patients
Neurobiologicalypothesis: Too much dopamine (a type of neurotransmitter) in brain; now we know this is too simple Brain has abnormal structures or does not function normally Viral infections during pregnancy that affect fetus
The
role of stress interactions
Stress may activate predisposition (vulnerability) and/or increase risk of relapse Families of people with schizophrenia show ineffective communication patterns
Schizophrenia has a strong genetic component
Females tend to have a better long-term prognosis Onset of schizophrenia differs between males and females
Schizophrenia affects males and females about equally
Most suffer with moderate-to-severe impairment throughout their lives Life expectancy in persons with schizophrenia is slightly less than average
The
Positive Symptoms
Abnormal behavior in active phase of illness; behavior that is not present when healthy Examples include delusions, hallucinations, and disorganized speech
Historical
Background
Emil Kraeplin – Used the term dementia praecox, focused on onset and outcomes Eugen Bleuler – Introduced the term “schizophrenia” or “splitting of the mind”