Modularity and Specialized Learning in the Organization of Behaviour
林业院校中“数据科学导论”的课程改革探索
计算机教学与教育信息化本栏目责任编辑:王力林业院校中“数据科学导论”的课程改革探索熊飞,曹涌,孙永科(西南林业大学大数据与智能工程学院,云南昆明650224)摘要:数据科学导论是数据科学与大数据专业中很重要的导论性课程,课程中涉及了统计学、计算机、机器学习和深度学习的大量前沿内容,具有理论复杂、知识点繁多的特点。
理工科基础较为薄弱的林业院校学生掌握难度较大。
本文提出了数据分析基础、机器学习与深度学习和数据管理与产品开发的三大模块构成的课程体系以及相应的教学模式,侧重于培养学生以数据为中心的思维模式,形成了符合林业院校特色的导论课程。
关键词:数据科学导论;课程改革;导论课程;林业院校;思维模式中图分类号:TP391文献标识码:A文章编号:1009-3044(2021)15-0147-03开放科学(资源服务)标识码(OSID ):Exploration on Course Reform of Introduction to Data Science in Forestry Universities XIONG Fei,CAO Yong,SUN Yong-ke(College of Big Data and Intelligent Engineering,Southwest Forestry University,Kunming 650224,China)Abstract:Introduction to Data Science is an important introductory course for Data Science and Big Data Technology,which covers a wide range of cutting-edge content in statistics,computers,machine learning,and deep learning.Therefore learning of this course is a challenging work for students that whitweak foundations in science and engineering in forestry universities.A teaching model focus on cultivating a data-centric mindset is introduced in this paper,which includes three parts:data analysis,Machine learning and deep learning,data management and product development.The redesign of Introduction to Data Science makes it con⁃form to the characteristics of forestry university.Key words:introduction to data science;course reform;introductory course;forestry universities;1引言2015年由国务院印发了《国务院关于印发促进大数据发展行动纲要的通知》标志着国家把大数据上升到了国家战略的层面,随后在2016年教育部在《教育部高等教育司关于2016年度普通高等学校本科专业设置工作有关问题的说明》中增加了数据科学与大数据技术专业(专业代码:08910T )来促进数据科学专业人才的培养。
软件工程的发展历程英语作文
软件工程的发展历程英语作文英文回答:The history of software engineering can be traced back to the early days of computer science, where the term "software" was first coined by John Tukey in 1958. In the beginning, software development was primarily focused on writing code to solve specific problems, with little regard for design or maintainability.As computers became more powerful and complex, the need for more structured and systematic approaches to software development became apparent. In the late 1960s and early 1970s, several seminal works emerged, such as Edsger W. Dijkstra's "Structured Programming" and David Parnas' "On the Criteria To Be Used in Decomposing Systems into Modules." These works laid the foundation for theprinciples of modularity, abstraction, and structured design that are still used today.In the 1980s, the software industry began to experience rapid growth, driven by the advent of personal computers and the rise of the internet. This led to a proliferation of software development methodologies, including agile development, object-oriented programming, and component-based development.The 1990s saw the emergence of the World Wide Web and the rise of e-commerce, which further fueled the demand for software and led to the development of new software development tools and technologies.In the 21st century, software engineering has continued to evolve, with the rise of cloud computing, artificial intelligence, and mobile computing. These technologies have introduced new challenges and opportunities for software engineers, who must now contend with issues such as scalability, security, and interoperability.Today, software engineering is a highly complex and specialized field, with a wide range of applications in every aspect of our lives. Software engineers play a vitalrole in developing and maintaining the software systemsthat power everything from our smartphones to our self-driving cars.中文回答:软件工程的发展历程。
我创造的宇航服英语作文
我创造的宇航服英语作文Venturing into the vast expanse of space requires meticulous preparation and specialized equipment to ensure the safety and well-being of astronauts. As an aspiring astronaut with a passion for innovation, I have dedicated myself to conceiving a cutting-edge宇航服 that transcends the limitations of current designs and empowers futurespace explorers to push the boundaries of human exploration.The foundation of my宇航服 lies in the integration of lightweight, ultra-strong materials. Advanced compositesand high-performance alloys seamlessly merge to create a robust exoskeleton that withstands the rigors of space, safeguarding the astronaut from micrometeoroid impacts, extreme temperatures, and cosmic radiation. Thislightweight construction minimizes energy expenditure, allowing astronauts to move with agility and precision during extravehicular activities (EVAs).Mobility is paramount in space exploration. My宇航服incorporates a groundbreaking joint design that mimics the natural range of human motion. High-performance actuators and sensors work in harmony to provide assisted movement, reducing fatigue and enhancing dexterity. The result is an 宇航服 that empowers astronauts to execute complex tasks with ease and precision, enabling them to conduct intricate repairs, deploy scientific instruments, and navigate challenging extraterrestrial landscapes.Life support is the cornerstone of any宇航服, and mine is no exception. A state-of-the-art life support system ensures that astronauts can breathe, stay hydrated, and regulate their body temperature in the unforgiving vacuum of space. Advanced filtration and purification technologies remove harmful contaminants from the air, while a closed-loop water system efficiently recycles water to minimize waste. Thermal regulation is achieved through a combination of insulation and active cooling mechanisms, ensuring astronaut comfort in extreme temperature fluctuations.Communication is vital for maintaining contact with mission control and fellow astronauts. My宇航服 features asophisticated communication system that seamlessly integrates voice, data, and video transmission. High-gain antennas and noise-canceling microphones deliver crystal-clear communication even in the most challenging environments. Astronauts can easily share real-time data, images, and video with ground teams, enabling effective decision-making and enhanced collaboration.Safety is non-negotiable in space exploration. My宇航服 incorporates multiple layers of redundancy and fault tolerance to minimize risks to the astronaut. Critical systems, such as life support and communication, are backed up by redundant components, ensuring uninterrupted operation in the event of a failure. Advanced sensors continuously monitor the宇航服's performance, providing real-time diagnostics and alerts to the astronaut and ground control.To maximize operational efficiency, my宇航服 is designed for modularity and adaptability. Its components can be easily swapped out and reconfigured to suit specific mission requirements. This modular design allows astronautsto customize their宇航服 to accommodate unique tasks and environments, reducing downtime and enhancing mission flexibility.Furthermore, my宇航服 incorporates cutting-edge technologies that push the boundaries of space exploration. Augmented reality (AR) overlays provide astronauts withreal-time information, navigation assistance, and interactive training modules, enhancing situational awareness and decision-making. Haptic feedback suits allow astronauts to interact with virtual objects and simulate tasks, providing valuable training opportunities and reducing the need for physical mock-ups.The宇航服 I envision is not merely a protective suit but a transformative tool that empowers astronauts to transcend the limitations of human frailty and embark on extraordinary space missions. Its lightweight, mobile, and adaptable design, coupled with advanced life support, communication, and safety systems, will enable astronauts to explore farther, stay longer, and achieve unprecedented scientific breakthroughs. As we venture deeper into thecosmos, my宇航服 will serve as a beacon of human ingenuity and determination, paving the way for a future where the boundless expanse of space is no longer an insurmountable barrier but an arena for limitless possibilities.。
志存高远学为基的英语作文
Ambition is the driving force of life,and learning is the foundation of achieving it. In the journey of life,it is essential to set lofty goals and persistently pursue them. However,without a solid foundation of knowledge,these ambitions may remain unattainable dreams.Learning is a lifelong process that encompasses various aspects,including academic knowledge,practical skills,and moral values.It is through education that we acquire the tools necessary to navigate the complexities of the world and to contribute positively to society.Firstly,academic knowledge forms the backbone of our learning.It provides us with a structured understanding of various subjects,enabling us to think critically and analytically.This foundation is crucial for solving problems and making informed decisions in our personal and professional lives.Secondly,practical skills are equally important.They allow us to apply theoretical knowledge in realworld situations.Whether its mastering a new language,learning to code,or acquiring leadership skills,practical skills enhance our ability to adapt and excel in different environments.Moreover,moral values are the guiding principles that shape our character and behavior. They teach us the importance of empathy,integrity,and respect for others.By instilling these values,we can build strong relationships and contribute to a more harmonious society.In conclusion,the pursuit of lofty ambitions is a noble endeavor,but it requires a solid foundation of learning.By embracing the process of lifelong learning,we can develop the knowledge,skills,and values necessary to achieve our goals and make a meaningful impact on the world.Let us strive to learn,grow,and reach for the stars,knowing that our education is the key to unlocking our full potential.。
大学英语中的内隐学习和外显学习
教 育 战 线168INTELLIGENCE大学英语中的内隐学习和外显学习佳木斯大学公共外语教研部 修婷婷摘 要:内隐学习和外显学习是两种不同类型的学习方式,同时也是当前教育领域研究的热点之一。
外显学习是认知的基本途径,内隐学习是认知必要的有益补充。
在语言学习过程中,不存在截然分开的内隐学习和外显学习,而应该使两种学习方式有机结合。
在大学英语学习中只有最大限度的发挥内隐学习和外显学习紧密结合的作用,才能提高大学英语的教学质量,构建理想的大学英语学习模式。
关键词:内隐学习 外显学习 大学英语教学一、引言现代心理学研究表明,外显学习(explicit learning)和内隐学习(implicit learning)是人类完成复杂学习任务、获得知识的两种最基本的方式(Bialystok 1994)。
外显学习是受意识控制,需要意识参与并采取一定策略的学习方式,是有目的、有选择性注意的学习方式,也是人类获得知识和认识世界最基本的方式之一,其根本特性是需要有意识地努力参与。
与外显学习相反,内隐学习则是没有明确地意识到或陈述出控制学习者的行为规则是什么,但却获得了这种规则的学习方式,即无意识地获得关于刺激环境情境中复杂知识的学习方法。
二、内隐学习、外显学习的内涵及其相互关系(一)内隐学习、外显学习的内涵内隐学习一词是由A.Reber 在1967年首次提出的,是指无意获得刺激环境地复杂知识的过程,同时以隐性的方式存储在大脑中,在应用时自动提取。
后来Reber 做了一系列的实验后指出人能够按照两种本质不同的模式来学习复杂的任务。
一种即为刚才提到的内隐学习,另外一种则是外显学习。
外显学习是受意志控制的,需要意识参与并采取一定策略的学习方式,是有目的、有选择性注意的学习方式,也是人类获取知识和认知世界最基本的方式。
(二)内隐学习、外显学习的相互关系1、关于内隐学习和外显学习的关系,国外二语习得领域中存在三种观点:(1)无接口理论。
大学改变生活英语作文
大学改变生活英语作文College life is a significant phase in ones life that brings about numerous changes both in terms of personal growth and the way one perceives the world. Here is an essay on how university can transform ones life.Title The Transformative Power of University EducationIntroductionThe journey from high school to university is not just a transition from one educational institution to another it is a leap into a world of new experiences ideas and opportunities. University life is a crucible that shapes individuals into wellrounded professionals and responsible citizens.Academic GrowthThe first and foremost change that university brings is academic. Unlike high school where the curriculum is rigid and standardized university offers a plethora of courses that cater to diverse interests. Students have the freedom to choose subjects that align with their passions and career goals. This autonomy in learning not only enhances academic curiosity but also fosters a deeper understanding of the chosen field.Development of Critical ThinkingUniversity education encourages critical thinking and problemsolving skills. Students are no longer spoonfed with information but are expected to question analyze and synthesize knowledge. This shift from rote memorization to analytical learning is a profound change that prepares students for the complexities of the real world.Cultural Exposure and DiversityOne of the most enriching aspects of university life is the exposure to diverse cultures and perspectives. Students from different backgrounds come together creating a melting pot of ideas and traditions. This cultural diversity broadens ones horizons fostering tolerance empathy and a global mindset.Social Skills and NetworkingUniversity is a social hub where students can forge lifelong friendships and professional connections. The various clubs societies and events provide platforms to develop social skills teamwork and leadership. These experiences are invaluable in building a strong network that can support ones career and personal life.Personal IndependenceLiving away from home for the first time many students experience personal independence for the first time. Managing finances time and daily responsibilities independently is a significant change that builds selfreliance and maturity. This autonomy is crucial in preparing students for life after graduation.Extracurricular ActivitiesParticipation in extracurricular activities is another way university life changes individuals. Whether its sports arts or volunteering these activities help students discover hidden talents develop new skills and gain a sense of accomplishment outside the academic sphere.ConclusionIn conclusion university life is a transformative period that goes beyond academic achievements. It is a time of personal growth where students develop critical thinking cultural awareness social skills and independence. The experiences gained during this phase lay the foundation for a successful and fulfilling life. Embracing the opportunities that university offers can truly change ones life for the better.。
台式电脑和笔记本电脑的优缺点 英语作文
台式电脑和笔记本电脑的优缺点英语作文全文共3篇示例,供读者参考篇1The Upsides and Downsides of Desktop PCs and LaptopsAs a student, having a reliable computer is absolutely essential for getting work done efficiently. With so many assignments, projects, research papers, and presentations, we rely heavily on technology to help us succeed academically. The two main types of computers available are desktop PCs and laptops, each with their own set of advantages and disadvantages. In this essay, I'll analyze the pros and cons of both to help determine which type of computer may be the better option for a student's needs.Let's start by looking at the benefits of desktop computers. One of the biggest advantages is sheer power and performance. Desktop PCs typically have faster processors, more RAM, and better graphics cards compared to laptops in the same price range. This extra horsepower allows desktops to handle intensive tasks like video editing, 3D modeling, gaming, and running multiple programs simultaneously with ease. If you're a studentmajoring in fields like animation, architecture, engineering or video production, a powerful desktop would be invaluable.Another key selling point for desktops is their upgrade potential. Unlike laptops where components are sealed away, desktop cases provide easy access to swap out parts like the CPU, RAM, storage drives and graphics card as needed. This modularity means you can keep upgrading and extending the lifespan of a desktop over many years rather than having to replace the entire machine. For cash-strapped students, this ability to upgrade incrementally is a major money-saver.Desktop PCs are also more ergonomic and comfortable to use for extended periods. You can connect a full-sized keyboard, mouse and large monitor (or multiple monitors) to customize the setup perfectly. This reduces the risk of strains or discomfort that can come from hunching over a compact laptop. Desktop cases also have better cooling systems with large fans to prevent overheating during demanding workloads.However, desktops have some significant downsides too. The biggest flaw is their lack of portability and mobility. A desktop PC is anchored to one location, chained by its tangle of cables and power cord. This isn't very convenient for students who need to take their work to class, the library, study groups orback home. Unless you only ever plan to use the computer in one stationary place, the immobility of a desktop will likely be too limiting.Desktops also have a larger physical footprint compared to laptops. Finding enough desk space to properly accommodate the tower case, monitor, speakers, etc. can be a challenge in cramped dorms or apartments. They also consume more power which translates to higher energy bills.Now let's examine the pros and cons of laptops. Portability is undoubtedly their biggest strength - you can easily slide a lightweight laptop into your backpack and work virtually anywhere. The self-contained, all-in-one design is perfect for the mobile lifestyle of students constantly moving between classes, the library, study rooms and home.Laptops today pack an impressive amount of computing power into their compact frames. High-end models can rival desktops in performance for most everyday tasks like writing papers, making presentations, browsing the web and streaming video. While lacking the extreme horsepower needed for specialized apps, laptops are more than capable for the majority of student needs.Battery life is another advantage unique to laptops. Power efficiency has improved dramatically, allowing modern laptops to last 8 hours or more on a single charge. This frees you from being tethered to a power outlet. Just charge it overnight and it's ready for a full day's worth of classes and studying.On the downside, laptops still can't quite match desktops in terms of raw performance and processing muscle. If your workload involves highly demanding software like professional video editing suites, CAD software or intense graphics work, a laptop may struggle compared to a fully loaded desktop rig.Upgrading is also extremely limited compared to desktops since laptop components are tightly integrated and difficult to access or swap out. At best, you may be able to upgrade the RAM and storage drive, but that's about it. High-end gaming laptops nowadays are somewhat more modular, but for most mainstream models, you're essentially stuck with the fixed hardware configuration until it's time to replace the entire laptop down the road.Limited port selection, especially on ultraportable laptops, is another downside. Running out of ports to connect all your peripherals can quickly become an inconvenience. Laptops alsogenerate more heat which brings higher fan noise and the potential for overheating issues.In terms of ergonomics, using a laptop for long periods can put a strain on your neck, back and wrists due to the compact design. Connecting an external monitor, keyboard and mouse creates a more ergonomic experience similar to a desktop, but this diminishes the intended portability benefit.So in summary, while desktop PCs offer the best raw performance, upgradeability and ergonomics, their complete lack of mobility is a major drawback for students. Laptops sacrifice some performance for portability and battery life. Weigh your specific needs and intended workloads carefully to determine which type of computer will serve you better as a student.My recommendation would be to get a reasonably powerful laptop as your main, portable workhorse. That covers you for doing work in class, at home, libraries, etc. Then, if you need extreme horsepower for specialized apps, invest in a mid-range desktop back in your dorm/apartment just for those intensive tasks. This gives you the best of both worlds - mobility and convenience combined with desktop-grade performance when you need it. That's the ideal setup in my book.篇2Choosing Between Desktop and Laptop ComputersAs a student, having a reliable computer is essential for completing assignments, conducting research, and staying connected. However, deciding between a desktop computer and a laptop can be a daunting task. Both options have their advantages and disadvantages, and it's crucial to weigh these factors carefully before making a choice.Desktop Computers: The Powerhouse PerformersPros:Power and Performance: Desktop computers are often more powerful than laptops, equipped with superior processors, more RAM, and dedicated graphics cards. This added computing power makes them ideal for resource-intensive tasks like video editing, 3D rendering, and gaming.Upgradability: Desktop computers are highly customizable, allowing users to upgrade individual components as needed. This flexibility ensures that the system can adapt to changing technological demands and remain relevant for a longer period.Ergonomics: With a desktop setup, you can choose a comfortable chair, position the monitor at an optimal viewing angle, and use a full-sized keyboard and mouse. This can help reduce strain and discomfort during extended periods of use.Cost-Effectiveness: Generally, desktop computers offer better value for money compared to laptops with similar specifications. The ability to upgrade individual components also helps extend the system's lifespan, making it a morecost-effective option in the long run.Cons:Lack of Portability: Desktop computers are stationary and cannot be easily moved from one location to another. This limitation can be a significant drawback for students who need to work on assignments or attend online classes while away from their home or dorm room.Space Requirements: Desktop setups typically require more physical space than laptops, as they consist of multiple components such as the tower, monitor, keyboard, and mouse. This can be a challenge in cramped living spaces or shared accommodations.Power Consumption: Desktop computers tend to consume more electricity than laptops, resulting in higher energy costs and a larger environmental footprint.Laptops: The Portable PowerhousesPros:Portability: The most significant advantage of laptops is their portability. Students can easily carry their laptops to class, the library, or any other location, allowing them to work on assignments, take notes, or attend online classes seamlessly.Space-Saving: Laptops are compact and take up minimal desk space, making them ideal for use in small living quarters or while traveling.Battery Power: Laptops run on rechargeable batteries, allowing users to work without being tethered to a power source. This flexibility is invaluable for students who need to work on the go or in areas with limited access to power outlets.Integrated Components: Laptops have all the necessary components, such as the display, keyboard, and trackpad, integrated into a single unit. This design eliminates the need for separate peripherals, further enhancing portability.Cons:Limited Upgradability: Laptops often have limited upgrade options, as components are tightly integrated and designed for compact form factors. This can make it challenging to extend the system's lifespan or keep up with rapidly evolving technological demands.Cooling Challenges: Due to their compact design, laptops can experience overheating issues, particularly when running resource-intensive applications or games. This can lead to performance throttling or system instability.Shorter Lifespan: Laptops generally have a shorter lifespan compared to desktop computers, as their components are more prone to wear and tear due to frequent transportation and handling.Ergonomic Considerations: Prolonged use of laptops can lead to ergonomic issues, such as neck and back pain, due to the compact keyboard and display positioning. External peripherals like a separate monitor, keyboard, and mouse may be required for comfortable extended use.The Choice: Balancing Needs and PreferencesUltimately, the decision between a desktop computer and a laptop comes down to your specific needs and preferences as astudent. If you prioritize performance, upgradability, and a dedicated workspace, a desktop computer may be the better choice. However, if portability, mobility, and the ability to work from anywhere are crucial, a laptop might be the more suitable option.It's also worth considering your academic field and the types of tasks you'll be performing. For example, students in fields like graphic design, video production, or engineering may benefit from the added power and flexibility of a desktop computer, while those in disciplines like journalism, business, or liberal arts may find laptops more suitable for their needs.Additionally, factors such as budget, living situation, and personal preferences should be taken into account. Some students may prefer the convenience of a laptop but supplement it with a desktop setup for more intensive tasks, while others may opt for a high-end laptop to meet their computing needs entirely.In the end, there is no one-size-fits-all solution. Both desktop computers and laptops have their strengths and weaknesses, and the ideal choice will depend on your individual requirements and circumstances. Carefully evaluating your needs, priorities, and preferences will help you make an informeddecision that aligns with your academic goals and lifestyle as a student.篇3The Great Debate: Desktop vs Laptop - A Student's PerspectiveAs a student in today's digital age, having a reliable computer is an absolute necessity. With countless assignments, research projects, and virtual learning platforms, our academic lives are heavily intertwined with technology. However, when it comes to choosing between a desktop computer or a laptop, the decision can be quite perplexing. Both options have their unique advantages and disadvantages, and it ultimately boils down to individual preferences and needs. In this essay, I will delve into the pros and cons of desktop computers and laptops from a student's perspective, shedding light on the factors that should be considered when making this crucial decision.Desktop Computers: The Powerhouse of ProductivityLet's start with the mighty desktop computer, a stalwart in the realm of computing power and performance. One of the most significant advantages of a desktop is its sheer processing capability. With the ability to house high-end components likepowerful processors, ample RAM, and dedicated graphics cards, desktops excel at handling resource-intensive tasks such as video editing, 3D modeling, and gaming. As a student pursuing creative fields or dealing with complex simulations, this computational prowess can be an invaluable asset.Another significant advantage of desktops is their upgradability. Unlike laptops, where components are often soldered and difficult to replace, desktops offer the flexibility to upgrade individual parts as needed. This means that instead of having to replace the entire system when it becomes outdated, students can simply upgrade specific components, extending the lifespan of their desktop and potentially saving money in the long run.Moreover, desktops typically offer larger screen real estate, which can be a boon for productivity. With the ability to connect multiple monitors, students can seamlessly multitask, effortlessly switching between research materials, writing assignments, and online resources. This enhanced workspace can significantly improve efficiency and reduce the need for constant window switching.However, desktops are not without their drawbacks. One of the most glaring disadvantages is their lack of portability. As astudent constantly on the move, attending classes, study sessions, and group meetings, the immobility of a desktop can be a significant limitation. Additionally, desktops tend to consume more power, which can translate into higher energy costs, an important consideration for budget-conscious students.Laptops: The Mobile Companion for Academic AdventuresLaptops, on the other hand, offer a unique set of advantages that cater specifically to the mobile lifestyle of a student. Portability is undoubtedly the most significant advantage of laptops. With their compact design and lightweight construction, laptops can be easily carried between classes, libraries, and study spots, allowing students to work wherever inspiration strikes.Furthermore, laptops offer unparalleled convenience in terms of note-taking and in-class engagement. With the ability to quickly jot down notes, access course materials, and participate in online discussions, laptops have become an indispensable tool for modern academic settings. The integration of touchscreens and stylus support in many laptops has further enhanced the note-taking experience, allowing students to seamlessly blend handwritten notes with digital content.Battery life is another crucial factor that makes laptops a compelling choice for students. With advancements in battery technology, many modern laptops can last an entire day on a single charge, eliminating the need for constant access to power outlets and enabling uninterrupted productivity during long study sessions or commutes.However, laptops also come with their own set of drawbacks. While they offer portability, they often sacrifice processing power and upgradability. Laptop components are generally less powerful than their desktop counterparts, and upgrading options are limited due to space constraints and thermal considerations. Additionally, laptops tend to have smaller screen sizes, which can be challenging for extended periods of multitasking or multimedia work.The Choice: Finding the Right BalanceUltimately, the decision between a desktop computer and a laptop comes down to striking the right balance between performance, portability, and individual needs. For students heavily involved in resource-intensive tasks like video editing, 3D modeling, or gaming, a powerful desktop setup might be the ideal choice, offering unparalleled performance and upgradability.On the other hand, for students who prioritize mobility and flexibility, a laptop can be the perfect companion, allowing them to work on-the-go while still providing adequate computing power for most academic tasks. Some students even opt for a hybrid approach, using a desktop for intensive tasks at home and relying on a laptop for portability when needed.Additionally, it's worth considering the financial aspect of the decision. While desktops generally offer better value for performance, laptops often come with a higher price tag due to their compact design and portability features. Students on a tight budget may need to carefully weigh their priorities and find the right balance between cost and functionality.In conclusion, the choice between a desktop computer and a laptop is a highly personal decision that should be guided by individual needs, academic requirements, and lifestyle preferences. By carefully evaluating the pros and cons of each option, students can make an informed decision that will not only enhance their academic experience but also set them up for success in their educational journey.。
模型训练与推理 英文
模型训练与推理英文Model Training and Inference.Model training and inference are two crucial stages in the development and deployment of machine learning models. Model training involves the process of feeding the model with labeled data to enable it to learn and make predictions. During training, the model adjusts itsinternal parameters to minimize the difference between its predictions and the actual labels. This is typically done using optimization algorithms such as gradient descent.On the other hand, model inference refers to the stage where the trained model is used to make predictions on new, unseen data. This could involve feeding new input data into the model and obtaining the corresponding output or prediction. Inference is the phase where the model's performance is evaluated based on its ability to generalize to unseen data and make accurate predictions.It's important to note that model training and inference have different computational requirements. Training a complex model often requires substantial computational resources and time, as it involves processing large amounts of data and performing numerous iterations to optimize the model's parameters. In contrast, inference is typically less computationally intensive, as it mainly involves applying the trained model to new data for prediction.Furthermore, the deployment of machine learning models for real-world applications often requires efficient and scalable inference mechanisms to handle varying workloads and ensure low latency. This may involve optimizing the model for inference, utilizing hardware accelerators such as GPUs or TPUs, and implementing techniques like model quantization to reduce the computational cost of inference.In summary, model training and inference are essential components of the machine learning lifecycle. Training enables the model to learn from data, while inference allows the model to make predictions on new data. Bothstages have distinct considerations in terms of computational requirements, performance evaluation, and real-world deployment.。
modularity算法
modularity算法Modularity algorithm is a popular algorithm used in community detection in complex networks. It was first introduced by Newman and Girvan in 2004 and has since been widely applied in various fields, including social network analysis, biological networks, and web graph analysis. The algorithm aims to identify densely connected groups or communities within a network by maximizing the modularity value.Modularity is a measure of the quality of a partition in a network. It quantifies the difference between the number of edges within a community and the number of edges expected in a random network with the same degree distribution. The modularity value, Q, ranges from -1 to 1, where a higher value indicates a better community structure. The algorithm iteratively merges and splits nodes to maximize the modularity value.The modularity algorithm can be summarized in several steps:1. Start with each node in its own community.2. Calculate the initial modularity value of the network.3. For each pair of nodes, calculate the change in modularity if they are merged into the same community.4. Merge the pair of nodes that results in the highest increase in modularity.5. Recalculate the modularity value after the merge.6. Repeat steps 3-5 until no further increase in modularity is possible or the desired number of communities is reached.The modularity value is calculated using the following formula:Q = (1/2m) * Σ [Ai, j - (ki * kj) / (2m)] * δ(ci, cj)where Ai, j is the number of edges between nodes i and j, ki and kj are the degrees of nodes i and j, m is the total number of edges in the network, ci and cj are the community assignments of nodes i and j, and δ(ci, cj) is the Kronecker delta function which is 1 if nodes i and j are in the same community and 0 otherwise.It is important to note that the modularity algorithm suffers from resolution limit, meaning it tends to detect larger communities while missing smaller ones. Various methods have been proposed to address this issue, such as the Louvain method and the Infomap algorithm.In conclusion, the modularity algorithm is a powerful and widely used algorithm for community detection in complex networks. It provides a quantitative measure of the quality of community structure and can help uncover the hidden organization within a network. By iteratively optimizing the modularity value, the algorithm identifies densely connected groups or communities. However, it is important to consider the limitations of the algorithm, such as the resolution limit, when applying it to real-world networks.。
重组抗体综述
Engineering antibody fragments: replicatingthe immune system and beyondFelipe García Quiroz Ψ, S. Michael SinclairBiomedical Engineering Department, Duke University, Durham, North Carolina, EE.UU.Received May 25, 2010. Accepted June 29, 2010L A INGENIERÍA DE FRAGMENTOS DE ANTICUERPOS : IMITANDO Y EXPANDIENDO EL SISTEMA INMUNEAbstract—Since genetic engineering of humanized murine monoclonal antibodies was fi rst demonstrated over two decades ago, antibody engineering technologies have evolved based upon an increasing understanding of the mechanisms involved in antibody generation in vivo , and a constant search for alternative routes to evolve and exploit the characteristics of antibodies. As a result, antibody engineers have devised innovative strategies for the rapid evolution and selection of antibodies and novel antibody designs (i.e., antibody fragments). Phage display, cell display and ribosome display technologies, which comprise thecore of the currently available technologies for the discovery and preparation of such antibodies, are reviewed herein. This article intends to communicate the state-of-the-art technology available for the engineering of antibodies to a general readership interested in this important fi eld. Therefore, important immunology concepts are introduced before detailed descriptions of the three antibody engineering technologies are presented in later sections. A comparison of these methodologies suggests that despite the predominance of phage display for the engineering of antibody fragments in the past 20 years, cell display and ribosome display will likely gain importance in the selection and discovery of the antibody fragments in the future. Finally, these technologies are likely to play an important role in the production of the next generation of antibody-based therapeutics.Keywords— Antibody engineering, Phase display, Cell display, Ribosome display, Antibody humanization.Resumen—Las tecnologías para la ingeniería de anticuerpos han evolucionado durante las últimas dos décadas, desde la demostración de la posibilidad de humanizar anticuerpos monoclonales de ratón mediante ingeniería genética, apoyadas en el creciente entendimiento de los mecanismos involucrados en la generación de anticuerpos in vivo , y en una búsqueda constante de rutas alternativas para evolucionar y explotar sus características. Es así como los ingenieros de anticuerpos han desarrollado estrategias innovadoras para la evolución y selección de anticuerpos y de novedosos diseños de anticuerpos conocidos como fragmentos de anticuerpos. Esta revisión se enfoca en tres tecnologías que comprenden el núcleo de las tecnologías actualmente disponibles para el descubrimiento y preparación de tales anticuerpos: la presentación en fagos, la presentación en células, y la presentación en ribosomas. Este artículo busca presentar el estado del arte de estas tecnologías a un grupo general de lectores interesados en este campo, por lo que inicialmente se introducen importantes conceptos de inmunología requeridos para comprender en detalle las tecnologías discutidas. Una comparación de estas metodologías para la ingeniería de anticuerpos sugiere que a pesar del dominio de las tecnologías basadas en la presentación en fagos durante los últimos 20 años, en los próximos años la presentación en células y la presentación en ribosomas probablemente ganarán importancia para la selección y descubrimiento de fragmentos de anticuerpos. Finalmente, es probable que estas tecnologías jueguen un papel importante en la producción de la siguiente generación de terapéuticos basados en anticuerpos.Palabras clave— Ingeniería de anticuerpos, Presentación en fagos, Presentación en células, Presentación en ribosomas,humanización de anticuerpos.Revista Ingeniería BiomédicaISSN 1909-9762, volumen 4, número 7, enero-junio 2010, págs. 39-51Escuela de Ingeniería de Antioquia-Universidad CES, Medellín, ColombiaΨContact e-mail: felipe.garcia@I. I NTRODUCTIONM ost recent reviews in the fi eld of antibody engineering have examined in great detail the dynamics of the clinical transfer of antibody engineering technology developed for therapeutic purposes. Substantial emphasis has been placed on the characteristics of the antibodies being used, their targets and mechanisms, and the opportunities and challenges for the continuous progress of the fi eld, particularly the remaining limitations of the state-of-the-art technology for antibody production [1-4]. Because of this emphasis, previous reviews have been directed toward a relatively specialized audience of antibody engineers in need of constant feedback on the increasing number of antibody-based therapeutic strategies under clinical trials, since the outcome of these trials signifi cantly affects new research initiatives and thus the evolution of the fi eld. However, the possibility to engineer human antibodies and novel related proteins against virtually any target has broad biomedical impact, providing for a means to neutralize (i.e., render inactive through antibody binding) key soluble proteins or receptors involved in the onset or progression of disease (e.g., chronic infl ammation, cancer), or develop a means to target and release additional therapeutic cargos to specifi c cell populations (e.g., cancer cells) in the body. Hence, this short review article is aimed at a more general readership, who may have an interest in this technology but may not be acquainted with the immunology concepts required for understanding the relevant literature in this fi eld. This review surveys the current technologies for engineering antibodies with a focus on the methodologies for developing antibody fragments and novel engineered proteins inspired by the structural components of complete antibodies. These novel technologies provide an important alternative to traditional antibody-based technologies and are often better suited for certain biomedical applications than conventional monoclonal antibodies.II. K EY IMMUNOLOGY CONCEPTSThis section introduces important immunology concepts essential to understanding antibody engineering strategies, their rationale, relevance, challenges and limitations. In some cases, the in vivo processes are contrasted with their engineered counterparts, although additional analogies will become evident throughout later sections of the article. These concepts may lie in any of three categories: (i) antibody structure and (ii) function, and (iii) diversity of the immune repertoires. Figure 1 summarizes basic information regarding antibody structure and function, and Fig. 2 and Table 1 detail the conceptsrelated to antibody diversity.Fig. 1. Structure and folding of immunoglobulins.(A) Schematic of the general structure of the four immunoglobulin G (IgG) isotypes, the predominant immunoglobulin class used in antibody engineering, which differ in the number and arrangement of disulfi de bonds and the heavy-chain component (γ1, γ2, γ3 and γ4, respectively; not shown in fi gure). The effector functions of each subisotype are indicated, since the ability to activate different receptors present in immune cells (i.e., effector functions mediated by Fc gamma receptors) plays a critical role in isotype selection for antibody engineering, and removal of constant domains can also prevent complement activation (e.g., C1) and other immune responses [5]. (B) Folding of an immunoglobulin light chain depicting the β-pleated sheet structure in each domain, the conserved disulfi de bond and the localization of the hypervariable regions (CDRs) in three loops joining β-strands of the variable domain. Images modifi ed from Goldsby et al. 2003 [6].Antibodies, or immunoglobulins, are heterodimers composed of two identical light (L) chains and two identical heavy (H) chains. One light chain is covalently linked to one heavy chain by a disulfi de bond, and the resulting H-L structures are joined as a dimer of dimers (i.e., H 2L 2) by additional disulfi de bonds between heavy chains (Fig. 1A). The heterodimeric structure is further stabilized by non-covalent interactions, such as hydrophobic interactions, hydrogen bonds, and salt-linkages. Early investigations into the structure of antibodies using enzymatic digestion helped to elucidate the Y-shaped structure of antibodies. Digestion with papain resulted into two antigen-binding fragments (Fab) and one crystallizable fragment (Fc), while digestion with pepsin resulted in a single antigen binding fragment comprised of two antigen-binding domains (F(ab’)2) [6]. Genetic analysis of antibodies isolated from human subjects provided further understanding of the immunoglobulin structure and variability. The fi rst 110 amino acids of the N-terminal segments of H and L chains are highly variable sequences called the V L and V H domains, which account for most of the differences in specifi city displayed by native antibodies [6]. The unique sequences of the V L and V H for a given antibody determine its idiotype (i.e., antigenic determinants). The cleft between a V L and V H chain is the antigen binding pocket, and the specifi city of antibody-antigen binding is predominantly controlled by 6 segmented, hypervariable loops called the complementarity-determining regions (CDRs) that extend from a highly ordered β-pleated structure characteristic of the immunoglobulin folding (Fig. 1B). While the CDRs are primarily responsible for antigen specifi city, the whole variable domain serves as a scaffold for the correct presentation of the binding site, and mutations along its sequence also infl uence, to a minor extent, antibody affi nity [4,6].The remaining amino acids of the H and L chains are highly conserved regions known as constant domains (C H or C L ). Heavy chains have 3 to 4 C H domains, whereas L chains have a single C L domain (Fig. 1) encoded by one of two light-chain genes, kappa (κ) or lambda (λ). The class of an antibody is determined by its heavy chain, of which there are fi ve different chains or isotypes: α, δ, ε, γ and μ. Immunoglobulin G (IgG) is made up of two γ heavy chains and is the most abundant (~80% of total serum immunoglobulin) and most studied immunoglobulin class for antibody engineering (Fig. 1A). The structure and functions of the other immunoglobulin classes (i.e., IgA, IgD, IgE and IgM), which play important roles in adaptive immunity, will not be discussed due to their minor role in current antibody engineering applications. Subtle amino acid differences encoded in the C H germ-line genes lead to a further division of isotypes into subisotypes or subclasses.In humans, for instance, there are four subisotypes of γ heavy chains (γ1, γ2, γ3, and γ4) with 90-95% homology between their genes. Additionally, different members of the same species may have multiple alleles for the same isotype genes, which determine the antibody allotype.The isotype and subisotype of an antibody strongly impact the structure and effector functions of the Fc region. Because of this, the selection of the isotype is relevant for engineering antibodies, since different applications may require the mediation of different effector functions or, even more, their absence [4,5]. The existence of different Fc regions modulates the binding to specifi c Fc receptors found in immune effector cells ―Fc gamma receptors (FcγR) in the case of IgG―, which trigger different effector functions upon binding of the antibody-antigen complexes, such as complement activation (component C1), antibody-dependent cell-mediated cytotoxicity (ADCC), opsonization (phagocytosis by macrophages and neutrophils) and transcytosis (crossing of epithelial layers). In the case of IgG, the Fc region also has the ability to bind to the neonatal Fc receptor (FcR N ), which plays a critical role in the regulation of IgG pharmacokinetics, since the binding to the FcR N constitutes a salvage mechanism that recycles IgG and therefore allows for prolonged serum half-lives. Despite the importance of the Fc fragment in the modulation of effector functions, and although it is amenable to tailoring antibody pharmacokinetics (i.e., select antibodies with increased affi nity to FcR N ) and has the ability to trigger specifi c effector functions (i.e., ADCC to tumor cells expressing the target antigen), the antibody engineering technologies discussed in this article focus on the antibody-antigen interaction, and are optimized and selected in formats devoid of Fc regions [2,7]. However, it should be noted that the modularity of the antibody structures also allows for the grafting of Fc regions into optimized antibody fragments (e.g., variable regions), although this usually requires the expression of the antibody fragment in eukaryotic expression systems [8].The ability of the immune system to generate antibodies against virtually any antigen depends on its ability to generate a suffi cient number of antibodies that can be selected based on their affi nity for binding the antigen. The mechanisms involved in the generation of such diversity span different levels of cell physiology and are tightly associated with the maturation and differentiation of B cells, which are responsible for their production and secretion in vivo [6]. The main mechanisms involved in the generation of antibody diversity, as depicted in Fig. 2, are further explained in Table 1, which account for the tremendous diversity (>1010) of the immune repertoire. In addition, the role of these mechanisms or their analogues in generating antibody diversity in existing antibody engineering technologies is indicated.Fig. 2. Rearrangement of immunoglobulin genes responsible for generating antibody diversity. The cartoon depicts the three main sources of variation resulting in the antibody repertoire diversity: combinatorial joining of the germ line V, D, J (H chain) or V and J (L chain) segments; imprecise joining of the coding sequences (junctional fl exibility) and random addition and deletion of nucleotides at the joint between segments; and fi nally somatic hypermutation along the VJ and VDJ regions for affi nity maturation during a T-cell-dependent secondary immune response [9]. Dotted (vertical) lines indicate non germ line encoded residues.Table 1. Principal sources of antibody diversity in humans. The overall diversity is believed to exceed 1010. Analogue mechanisms, such as error prone amplifi cation of the variable regions are harnessed for the generation of diversity in synthetic and semisynthetic antibody libraries. Similarly, all the mechanisms below account for the diversity available in in vivo models for antibody generation, such as transgenic mice expressing repertoires of human antibody genes [6,9-11].Source of variation Mechanism Calculated diversity Role in antibody engineeringCombinatorial V-J and V-D-J joining Heavy chain: combinations of 51 VHgenesegments, 27 DHand 6 JHsegments.Light chain: combinations of 40 VLand 5 JLkappa chains; and of 30 VLand 4 JLlambdachains.8262 for Heavy chainand 320 for Lightchain.In vitro combinatorial assembly of thenaïve immune repertoire (V-J andV-D-J segments).Construction of synthetic libraries witha subset of VHand VLgene families.Junctional fl exi-bility Imprecise joining of the coding sequencesduring recombination of the gene segments.Undetermined N.AP-nucleotide addi-tions Variation in the sequence of the coding jointdue to imprecise cutting of the hairpin struc-ture formed during the initial recombinationprocess, leaving a single strand at the end ofthe coding sequence. A repair enzyme addscomplementary nucleotides to this strandforming a palindromic (P) sequence.Undetermined N.AN-nucleotide addi-tions Random nucleotides added during the DHJHand VHto DHJHjoining process by a terminaldeoxynucleotidyl transferase (i.e., addition ofresidues not encoded in the germ line genes).Undetermined N.A.Somatic hypermu-tation Mutations along the whole VJ and VDJsegments, although the mutations are usuallyconcentrated in the CDR regions probably dueto their major contribution to the affi nity matu-ration of the antibodies. The process occurs ata frequency ~ 103 per base pair per generation.Undetermined Error prone amplifi cation of the varia-ble regions.Site-directed mutagenesis at the CDRs.Combinatorial ligation of CDR-enco-ding regions.[Important for affi nity maturation].Possible combina-torial association of heavy and light chains Combinatorial association of 8262 heavychains and 320 light chains.2.64x106Direct amplifi cation of the antibodyrepertoire (assembled genes) fromimmunized animals by RT-PCR.Ligation of synthetic variable lightand heavy genes.III. E NGINEERING ANTIBODY FRAGMENTSThe modular structure of antibodies has enabled thecustomization and engineering of high affi nity binders in a variety of ways. Before discussing the technologies developed for the design and discovery of antibody fragments, the available antibody fragment formats are presented, since those technologies, as will be noted in section IV , are only suited for particular antibody formats. Figure 3 depicts the available battery of antibody fragments derived from the parental IgG structure. The seminal work on the engineering of these new sets of antibody formats was conducted on Fab fragments ―comprised of one antigen binding site of an IgG (V H -C H +V L -C L )―, and on single-chain variable fragments (scFv), a further simplifi cation of the Fab structure achieved by removing the constant domains and linking the V H and V L fragments with a peptide linker [1]. The scFv format rapidly popularized, and is probably the most widely used antibody fragment today, mainly due to the advantages of directly linking the heavy and light domain genes. Linking these domains at the genetic level not only simplifi ed the recombinant DNA methods involved in their processing, but signifi cantly increased the stability of the structure and eliminated the folding problems encountered with prokaryotic expression systems (e.g., E. coli) during selection and production of antibodies with disulfi de bonds [2,8]. Interestingly, the incorporation of the peptide linker and the variation of its length has been found to control the dimerization properties of the scFv fragments, with shorter sequences resulting in increasing valency (diabody, triabody and tetrabody formats have been produced). Theabsence of linker, which prevents the self-folding of the V H and V L domains of one scFv promotes the formation of bispecifi c scFv by noncovalent interactions between the variable domains of a second scFv [3].The maximum simplifi cation of the antibody structure, known as domain antibody (dAb), consists of a single V H or V L domain (i.e., only 3 CDRs). The initial attempts to derive high affi nity binders using dAb were not encouraging, resulting in the selection of fragments displaying signifi cant decreases in binding affi nity, but most importantly, poor stability and a tendency to aggregate [1]. Nevertheless, the fi nding of dAb naturally occurring in camels, which displayed high affi nity and stability, inspired the design of new dAb circumventing these problems, in a process termed “camelization” [12]. Despite the success of the camelization approach, the therapeutic applications of such antibodies were limited due to the potential immunogenicity associated with using non-human scaffolds in the variable region design [2]. Only recently, Winter and coworkers, in their efforts to characterize a set of dAbs produced against hen egg lysozyme (HEL), discovered an antibody domain displaying similar properties to those found in camel and llama V H H Abs but without recurring to camel-based scaffolds (i.e., camelising mutations). The same group also devised a methodology for the generation of equally stable and aggregation-resistant domain antibodies [13]. One important realization of this work was the increased understanding of the role of the CDRs in determining the thermodynamic stability, as well as expression and purification yields, of antibodies [11,12].Fig. 3. Schematic of the most common engineered antibody fragments. The molecular weight (MW) of the fragments varies from 15 KDa for the light and heavy variable domains, V L and V H respectively, with serum half-lives (t) of 0.05 h, through 100 KDa in single-chain variable fragments (scFv) with a crystallizable fragment (Fc), scFv-Fc, and a half-life of 12 h, to 165 KDa in the trispecifi c Fab (antigen binding fragment), F(ab’)3. dsFv: disulphide-stabilized scFv. Image modifi ed from Carter, 2006 [3]; pharmacokinetics and MW data was taken from Holliger and Hudson, 2005 [2].IV. A NTIBODY ENGINEERING TECHNOLOGIESThe discovery of the hybridoma technology in 1975 enabled the production of monoclonal antibodies (mAbs) and paved the way for the evolution of the Antibody Engineering fi eld [14]. The therapeutic potential of such technology became evident in 1984, when Winter and collaborators demonstrated an ability to form chimeric antibodies with murine antigen-binding domains and complete human effector functions (i.e., Fc region). In 1986, the same group developed the groundbreaking antibody humanization technology, which involves transferring the CDR regions of a murine monoclonal antibody into a human immunoglobulin scaffold, signifi cantly reducing the immunogenicity issues associated with murine antibodies [15]. Current antibody engineering technologies have surpassed many of the challenges imposed by the selection of antibodies using murine cell lines (i.e., hybridoma technology), eliminating the need for humanization by enabling the production of fully human antibodies in vitro or in other engineered animal models. Hence, the technologies presented in this section will focus on these alternative methods for the selection and production of human antibody fragments.4.1 Antibody librariesAs explained in section II, the diversity of the immune repertoire is critical for the successful isolation and production of high affi nity antibodies [16]. Indeed, library characteristics, such as size (overall diversity) and quality (i.e., number of functional combinations), dictate the ability to express relevant antibody fragments against a particular antigen [1,17,18]. Therefore, the screening technologies presented in the next section are strongly dependent on the characteristics of the antibody library being used.Due to the complexity of the immune repertoire, the initial approaches for the construction of antibody libraries followed a simple strategy: the amplifi cation of assembled antibody genes after mice immunization by means of RT-PCR using a set of primers designed for the amplifi cation of all antibody genes and based on the variable region frameworks (already known by the time and deposited in data bases: Kabat and V-base database) [19]. However, this approach still used mice for the generation of the assembled antibody genes after immunization, therefore presenting only partial advantages. An additional level of complexity was included by applying a similar strategy for the amplifi cation of naïve libraries (i.e., gene segments before recombination) from non-immunized animals followed by in vitro combinatorial assembly of the antibody repertoire [10].Despite these signifi cant advances, the antibody fragment screening and production technologies relied on non-mammalian systems, which suffer from inadequate expression levels and other problems derived from differences in codon usage. As a result, the development of semisynthetic and later of fully synthetic human antibody libraries represented an important achievement for the antibody engineering fi eld. These libraries can now be optimized for expression according to the selection technology and desired expression system, have modular designs that allow relatively easy interconversion between different antibody formats, and signifi cantly simplify laborious DNA manipulation steps. In addition, synthetic libraries are not limited by the bias introduced in germ-line repertoires throughout evolution, such as the tolerance mechanism against selection of self-antigens, and therefore enable, at least in theory, the discovery and selection of antibodies with no representation in natural immune repertoires [4,20].Figure 4 presents the designs of the most advanced human synthetic libraries currently available, which are known as Human Combinatorial Antibody Libraries (HuCAL) [17,21]. Initially introduced in 2000, this synthetic library implemented innovative concepts for the generation of diversity, including diversity not only in the CDRs but also in the framework regions, which are known to play a role in CDR conformation. In addition, the diversity introduced in the CDR libraries is biased towards sequences predominant in the human immune repertoire (by using trinucleotide cassette mutagenesis), which facilitates the selection of antibody fragments with minimal or no immunogenicity (human anti-human antibody, HAHA) [9,16]. It is worth noting that the diversity in the VHand VLgene families, as well as the families selected, were carefully analyzed by bioinformatics means to achieve suffi cient diversity while preventing excessive complexity of the library. Indeed, this library only uses 7 master genes for heavy chains and 7 genes for light chains corresponding to consensus sequences for seven VHand seven VLgerm-line families which were found to account for more than 95% of the human antibody diversity observed in vivo. The library was initially developed in scFv format, but is now also available for Fab fragments [10]. Some characteristics of the newest versions of the HuCAL library (Fig. 4B and 4C), HuCAL Fab 1 and HuCAL GOLD, that require special attention are: (i) the absence of cysteine residues in the constant domains (eliminated to avoid problems during expression), (ii) that only Fd (VH+ CH) is covalently attached to pIII (for phage display, reviewed in next section), so that the system depends on the non-covalent interactions with the light chain, and (iii) the absence of cysteine residues in the CDR regions in the HuCALGOLD library (to avoid problems with the CysDisplay TM technology). Although (ii) may be complicated by light chain exchange in a given phage preparation, thereby losing the linkage of genotype to phenotype, the authors claim that after extensive use of the library this non-covalent interaction proved very stable [20,21].Two powerful technologies for screening antibody libraries and selecting antibodies of high affi nity for a particular antigen involve the display of one (monovalent) or several (multivalent) antibody particles on the surface of either phage virion, phage display (section 4.2), or on the cell surface (i.e., cell wall, cell membrane) of a prokaryotic or eukaryotic host, cell display (section 4.3). 4.2 Phage displayPhage display is a powerful biomolecular engineering technique for selecting high affi nity binders to biologically relevant targets by several rounds of affi nity selection. Foreign DNA encoding recombinant peptides or proteins is fused to coat protein DNA of bacteriophage such that recombinant molecules will be expressed and displayed on the outer surface of the phage. This strategy effectively links the protein phenotype and genotype (i.e., the corresponding DNA carried by the phage) thereby enabling the simple identifi cation of the selected proteins at the DNA level. In the seminal publication of phage display [22], fragment genes of the endonuclease EcoRI were fused to the gene III protein (g3p) of fd fi lamentous phage to produce “fusion phage” capable of yielding peptides with 1000-fold higher affi nity for anti-EcoRI antibody. Winter’s group then demonstrated the possibility to display functional antigen-binding sites on the surface of these phage particles for their evolution [23,24], and subsequently contributed to the seminal work on the construction of large phage antibody libraries [25]. By linking phenotype to genotype, vast libraries of phage (109-1012 clones) displaying different fusion proteins can be assembled, selected for with simple affi nity techniques (Fig. 5A), and quickly identifi ed by conventional DNA sequencing [26]. Marks et al. (1991) prepared a library of scFv genes from peripheral blood lymphocytes isolated from unimmunized human donors by RT-PCR, which contained randomly generated heavy and light chain variable fragments. After affi nity selection, phage displaying scFv demonstrated affi nity for theirtarget Fig. 4. Modularity and diversity in synthetic human antibody libraries. (A) General format of the 49 scFv master genes comprising the HumanCombinatorial Antibody Libraries (HuCAL) scFv (VH -VLorientation), where the scFv cassette is preceded by a phoA signal sequence (reporteralkaline phosphatase for screening and expression purposes) and a FLAG tag (purifi cation purposes), and the VH -VLdomains are fused by a peptidelinker; diversity is further incorporated by pre-built CDR3 cassettes libraries yielding a library size of 2x109(~61% functional sequences). (B) HuCAL- Fab 1 library generated from the original HuCAL scFv library, with all master genes in Fab format and library size of 2.1x1010 (~67% functional sequences). (C) Most recent version of the HuCAL library, HuCAL GOLD, incorporating diversity in all six CDRs and adapted for antibody selection by CysDisplay TM. Images reproduced from (A) Knappik et al. 2000, (B) Rauchenberger et al. 2003 and (C) Rothe et al. 2008 [10,20,21].。
英语作文自己发明的东西
英语作文自己发明的东西Here is an English essay about an invention of my own, with the content exceeding 1000 words as requested. The title is not included in the word count.I have always been fascinated by the world of innovation and technology. From a young age, I have been constantly dreaming up new ideas and concepts, imagining how I could create something that would make a difference in people's lives. It is this innate curiosity and drive to problem-solve that has led me to develop my own invention, one that I believe has the potential to revolutionize a particular industry.The inspiration for my invention came from a personal experience I had a few years ago. I was traveling abroad and found myself in a remote village with limited access to essential resources. As I navigated the challenges of daily life in this unfamiliar environment, I couldn't help but notice the significant disparities in access to basic necessities that many people in the developing world face on a regular basis. This experience truly opened my eyes to the pressing need for innovative solutions that could address these global inequities.After returning home, I began to meticulously research and brainstorm ideas that could potentially alleviate some of the problems I had witnessed. I spent countless hours poring over academic papers, industry reports, and expert interviews, trying to identify a specific area where my skills and expertise could make a meaningful impact. It was during this extensive research phase that the concept for my invention began to take shape.The core of my invention is a portable, self-sustaining water purification system that can be easily deployed in remote or resource-constrained regions. The system utilizes a combination of cutting-edge filtration technologies and renewable energy sources to provide clean, safe drinking water to communities in need. Unlike traditional water purification methods that often rely on centralized infrastructure and constant access to electricity, my invention is designed to be highly versatile and adaptable to a wide range of environmental conditions.At the heart of the system is a compact, lightweight filtration unit that can remove a vast array of contaminants, including bacteria, viruses, heavy metals, and even harmful chemicals. This filtration unit is powered by a integrated solar panel and battery system, ensuring that the device can operate independently of traditional power sources. The system also features a built-in water storage tank,allowing it to provide a continuous supply of clean water even in areas with limited access to surface water or groundwater.One of the key innovations of my invention is its modular design, which allows for easy customization and scalability. The filtration unit, solar panel, and water storage components can be easily assembled and configured to meet the specific needs of a given community or region. This modularity not only simplifies the installation process but also enables the system to be easily maintained and repaired by local users, reducing the need for specialized technical support.To further enhance the accessibility and affordability of my invention, I have designed it to be manufactured using readily available, low-cost materials. By leveraging local supply chains and production capabilities, I aim to ensure that the system can be produced and distributed at a price point that is within reach of the communities that need it most.In addition to its practical applications, my invention also incorporates a robust educational component. The system is accompanied by a comprehensive user manual and training materials, empowering local communities to understand the technology, maintain the system, and ultimately take ownership of their water security. This educational aspect is crucial in fostering long-term sustainability and ensuring that the benefits of the inventioncontinue to be realized long after its initial deployment.As I continue to refine and develop my invention, I have also been actively seeking partnerships with non-governmental organizations, government agencies, and private sector entities that share my vision of improving access to clean water globally. These collaborations have not only provided valuable feedback and resources but have also opened up new avenues for testing, deployment, and scaling of the technology.One such partnership has been with a leading international development organization that has expressed interest in piloting my invention in several remote communities in sub-Saharan Africa. Through this collaboration, we have been able to gather valuable data on the real-world performance and impact of the system, as well as refine the design based on user feedback and local environmental conditions.As I look to the future, I am filled with a sense of optimism and determination. I believe that my invention has the potential to make a tangible difference in the lives of millions of people around the world who currently lack access to clean, safe drinking water. By continuing to innovate, collaborate, and advocate for this technology, I am confident that we can work towards a future where clean water is a basic human right, rather than a privilege.Of course, the journey of bringing an invention to life is not without its challenges. I have faced numerous setbacks and obstacles along the way, from securing funding and navigating complex regulatory environments to overcoming technical hurdles and garnering buy-in from skeptical stakeholders. However, I have remained steadfast in my commitment, driven by the knowledge that the impact of my invention could be truly transformative.As I reflect on the process of developing my invention, I am struck by the immense power of human ingenuity and the ability of individuals to create solutions that can positively shape the world around them. This experience has reinforced my belief that innovation, when coupled with a deep understanding of societal needs and a genuine desire to make a difference, can be a powerful force for good.Moving forward, I am excited to continue refining and expanding the capabilities of my invention, exploring new applications and partnerships that can further amplify its impact. I am also committed to sharing my story and inspiring others, particularly young aspiring inventors and engineers, to pursue their own dreams of creating transformative technologies that can improve the human condition.In conclusion, the development of my invention has been a deeply rewarding and humbling journey. It has challenged me to thinkcreatively, to problem-solve in the face of adversity, and to relentlessly pursue a vision that I believe can make a tangible difference in the world. As I look ahead, I am filled with a sense of purpose and a deep conviction that the power of innovation can indeed change lives, one community at a time.。
大学自律 英语作文
Selfdiscipline is a crucial aspect of personal development,particularly for university students who are transitioning from a structured high school environment to the more independent setting of higher education.Here are some key points to consider when discussing the importance of selfdiscipline in a university setting:1.Time Management:University students are often faced with numerous assignments, projects,and exams.Selfdiscipline helps in effectively managing time,ensuring that all academic responsibilities are met without compromising on the quality of work.2.Academic Integrity:With the freedom to explore various subjects,students must be disciplined to avoid plagiarism and maintain academic honesty.This not only reflects well on their character but also contributes to the integrity of the academic community.3.Healthy Lifestyle:Selfdiscipline extends beyond academics to include maintaining a healthy lifestyle.This includes regular exercise,a balanced diet,and sufficient sleep,all of which are essential for optimal cognitive function and overall wellbeing.4.Financial Responsibility:University students often live away from home for the first time and must learn to manage their finances.Selfdiscipline in spending and saving can prevent students from falling into debt and ensure they can focus on their studies without financial stress.5.Social Balance:While socializing is an important part of the university experience, selfdiscipline is necessary to balance social life with academic commitments.It helps students avoid distractions and maintain a healthy balance between work and play.6.Goal Setting:Setting and achieving goals requires selfdiscipline.Students who are disciplined are more likely to set realistic goals,create a plan to achieve them,and follow through with the necessary steps.7.Adaptability:Universities offer a diverse and dynamic environment.Selfdiscipline helps students adapt to new situations,manage stress,and overcome challenges that may arise during their academic journey.8.Lifelong Learning:The ability to selfmotivate and continue learning independently is a skill that extends beyond university.Selfdiscipline fosters a lifelong learning mindset, which is invaluable in todays rapidly changing world.9.Professional Development:Selfdiscipline is a trait that employers value.University students who exhibit selfdiscipline are likely to be more successful in their future careers,as they can take initiative,meet deadlines,and work well both independently and as part of a team.10.Personal Growth:Ultimately,selfdiscipline contributes to personal growth.It helps students develop resilience,selfawareness,and a sense of responsibility for their actions and decisions.In conclusion,selfdiscipline is not just a tool for academic success but also a foundation for personal and professional development.University students who cultivate selfdiscipline are better equipped to navigate the challenges of university life and are more likely to thrive in their future endeavors.。
计算机科学英语词汇大全掌握计算机科学领域的专业术语和常见缩略词
计算机科学英语词汇大全掌握计算机科学领域的专业术语和常见缩略词在计算机科学领域,掌握专业术语和常见缩略词是非常重要的,这有助于更好地理解和沟通。
本文将为您整理一份计算机科学英语词汇大全,以便您学习和掌握这些专业术语。
以下是常见的计算机科学英语词汇及其解释:1. Algorithm(算法): A set of predefined rules or instructions used to solve a specific problem or perform a specific task in a computer program.2. Binary(二进制): A numbering system that consists of only two digits, 0 and 1. It is widely used in computer systems as the fundamental language for representing data and performing calculations.3. Compiler(编译器): A software tool that translates high-level programming languages into machine language or assembly language, which can be directly executed by a computer.4. Database(数据库): A structured collection of data that is organized and stored in a computer system. It allows users to easily retrieve, update, and manage data efficiently.5. Encryption(加密): The process of converting data into a form that is unreadable by unauthorized users. Encryption is used to ensure the security and privacy of sensitive information.6. Firewall(防火墙): A network security device that monitors and controls incoming and outgoing network traffic based on predeterminedsecurity rules. It acts as a barrier between a trusted internal network and untrusted external networks.7. HTML (Hypertext Markup Language)(超文本标记语言): The standard markup language used for creating and structuring web pages. It defines the structure and layout of the content on a webpage.8. GUI (Graphical User Interface)(图形用户界面): A visual interface that allows users to interact with a computer or software using graphical elements, such as windows, icons, buttons, and menus.9. Kernel(内核): The core component of an operating system that manages system resources and provides low-level services to other software applications.10. Machine Learning(机器学习): A branch of artificial intelligence that enables computer systems to learn and improve from experience without being explicitly programmed. It focuses on the development of algorithms that can analyze and interpret data to make predictions or decisions.11. Network(网络): A collection of interconnected devices, such as computers, servers, routers, and switches, that allows for the exchange of data and resources.12. Object-Oriented Programming(面向对象编程): A programming paradigm that organizes software design around objects, rather than logic and procedures. It emphasizes the reusability, modularity, and extensibility of code.13. Protocol(协议): A set of rules and standards that govern the communication between devices on a network. Protocols ensure that data is transmitted and received correctly.14. Query(查询): A request for specific information or data from a database using a query language, such as SQL (Structured Query Language).15. RAM (Random Access Memory)(随机存取存储器): A type of computer memory that stores data that is being actively used by a computer program. It allows for faster access to data compared to other types of storage.16. Software Development(软件开发): The process of designing, coding, testing, and maintaining software applications and systems. It involves various stages, such as requirements analysis, design, implementation, and deployment.17. TCP/IP (Transmission Control Protocol/Internet Protocol)(传输控制协议/互联网协议): A set of networking protocols that allows computers to communicate and exchange data over the internet. It provides a reliable and standardized method for transmitting data packets.18. Virtual Reality(虚拟现实): A computer-generated simulation of a three-dimensional environment that can be interacted with and explored by a user. It typically involves the use of specialized hardware, such as headsets and motion controllers.19. Web Development(网站开发): The process of creating and maintaining websites and web applications. It includes tasks such as webdesign, web content development, client-side scripting, and server-side scripting.20. XML (eXtensible Markup Language)(可扩展标记语言): A markup language that is designed to store and transport data. It is widely used for representing and exchanging structured data over the internet.这些是计算机科学中的一些常见英语词汇和术语。
项目式学习在我国各学科的应用研究综述
Creative Education Studies 创新教育研究, 2023, 11(7), 1963-1971 Published Online July 2023 in Hans. https:///journal/ces https:///10.12677/ces.2023.117292项目式学习在我国各学科的应用研究综述来桂佩肇庆学院马克思主义学院,广东 肇庆收稿日期:2023年6月6日;录用日期:2023年7月18日;发布日期:2023年7月28日摘要 2022年出台的新版《义务教育课程方案和课程标准(2022年版)》中,关于课程标准的首要改变就是强化育人标准,突出学生核心素养和关键能力的培养。
不同于中国传统的教育模式,作为一种动态学习模式的项目式学习目前在国内被广泛应用于各学科、各领域。
文章基于中国知网数据库,在数据库中运用“项目式学习”检索词检索后,以学前教育、初等教育、中等教育和高等教育等不同学科进行统计,分析项目式学习在各学科的应用情况和程度。
关键词项目式学习,学科,应用A Review of the Application Research of Project-Based Learning in Various Disciplines in ChinaGuipei LaiSchool of Marxism, Zhaoqing University, Zhaoqing Guangdong Received: Jun. 6th , 2023; accepted: Jul. 18th , 2023; published: Jul. 28th , 2023AbstractIn the new edition of Compulsory Education Curriculum Scheme and Curriculum Standards (2022 Edition) published in 2022, the first change of curriculum standards is to strengthen the education standards and highlight the cultivation of students’ core literacy and key abilities. Different from the traditional education model in China, project-based learning, as a dynamic learning model, is widely used in various disciplines and fields in China. Based on the database of China National Knowledge Infrastructure (CNKI), this paper uses the term “project-based learning” to search in来桂佩the database, and makes statistics on different disciplines such as preschool education, primary education, secondary education and higher education, and analyzes the application and degree of project-based learning in various disciplines.KeywordsProject-Based Learning, Subject, Application Array Copyright © 2023 by author(s) and Hans Publishers Inc.This work is licensed under the Creative Commons Attribution International License (CC BY 4.0)./licenses/by/4.0/1. 概念概述“项目式学习”是一种动态的、以学生为中心的学习方法,教师通过支持、建议和指导为学生提供一些关键素材构建一个环境,学生通过分组在此环境里主动探索,经过自己的思考和推理解决一个开放式的问题来学习。
英语作文 上课方式
When it comes to the ways of teaching English,there are several methods that can be employed to ensure an engaging and effective learning experience for students.Here are some common approaches used in English classes:1.Lecture Method:This traditional approach involves the teacher delivering information to the class.Its useful for introducing new concepts and providing explanations.However, it can be less interactive and may not cater to all learning styles.2.DiscussionBased Learning:Encouraging students to discuss topics in pairs or small groups can promote critical thinking and language practice.This method helps students to articulate their thoughts and listen to different perspectives.3.InquiryBased Learning:Students are encouraged to ask questions and explore topics on their own.This method can foster curiosity and independent learning skills.4.ProjectBased Learning PBL:Students work on projects that require them to apply language skills in a practical context.This can include presentations,written reports,or creative projects that demonstrate their understanding of the language.nguage Immersion:This method involves teaching English in a way that mimics a nativespeaking environment.It can be achieved through conversational practice, roleplays,and using English exclusively during class time.6.TechnologyAssisted Learning:Utilizing multimedia tools,online platforms,and educational software can enhance the learning experience.This can include interactive whiteboards,language learning apps,and online resources for practice and research.7.Peer Teaching:Allowing students to teach each other can build confidence and reinforce learning.It can also provide a different perspective on the material.8.Flipped Classroom:In this approach,students learn new content online by watching video lectures or reading materials outside of class.Class time is then used for discussion, clarification,and application of the knowledge.9.TaskBased Learning:Students complete tasks that require them to use English in a functional way.This can include writing emails,making phone calls,or solving problems that require language use.10.Assessment for Learning:Regular assessments can help students and teachers understand progress and areas for improvement.This can include quizzes,tests,andselfassessments.11.Differentiated Instruction:Tailoring teaching methods to meet the needs of different learners can enhance the learning experience.This might involve providing different levels of difficulty,using various teaching aids,or offering alternative ways to demonstrate understanding.12.Cultural Integration:Incorporating elements of Englishspeaking cultures into lessons can make learning more relevant and interesting.This can be done through literature, music,films,and discussions about cultural customs.Each method has its own strengths and can be adapted to suit the needs of the students and the goals of the curriculum.A combination of these approaches often yields the best results,as it caters to a variety of learning preferences and styles.。
Research on the Reform of College English Teaching
Research on the Reform of College English Teaching under the Background of New Liberal ArtsTalehati AilimubieerdiSchool of Foreign Languages, Yili Normal University Abstract: English is the key content in students’ learning, which is also the foundation for students to learn and communicate in the future. The reform content of the new curriculum standard clearly pointed out: Teachers should improve the actual efficiency of college English teaching, expand English training by guiding college students to have interesting thinking activities, and improve their ability to learn. If teachers want to improve the English literacy of students, they should actively promote reading education. The launch of college English plays a key role in broadening the knowledge and horizons of college students and improving their English literacy and reading ability. Therefore, the dissertation mainly analyzes the problems of college English teaching and the specific teaching strategies under the background of the new liberal arts so as to promote students’ English literacy and comprehensive development.Keywords: College English; English teaching; The new liberal arts; Reform strategiesDOI: 10.47297/wspciWSP2516-252710.20210501R eading is an important content in English teaching, which is also an extension of reading activities in class, and an important part to cultivate college students’ reading skills. Efficient reading activities can make in-class English activities more effective. And this requires college English teachers to pay full attention to English teaching, fully understand the difficulties faced by English teaching today, and innovate reading strategies based on the personality and characteristics of each college student in the class so as to effectively improve the learning quality of student.About the author: Talehati Ailimubieerdi (1981-04) , Male, Kazakh. Birth Place: Xinyu-an, Xinjiang, School of Foreign Languages, Job title: Lecturer, Master degree, Research Interest: linguistics and Applied Linguistics.Research on the Reform of College English Teaching under the Background of New Liberal Arts 1. The Dilemma of College English T eaching(1) Low Motivation of Students to LearnFor college students, they do not concentrate on learning English compared with their own professional courses, when they are learning English content because they think that English lessons are not important. Therefore, there are not enough interests of student when learning English content, and they also have low motivation to learn. After class, students would not look at the content of English. In the daily teaching, when teachers explain the content in English courses, the rate of students to raise their heads is obviously lower than that of other courses and only some students like to learn content related to English. Judging from final assessments of students, most students answer questions by searching for information on the internet, and do not have their own opinions. Some students even make some very low-level mistakes. When listening to the English course, most of the students do not willing to answer questions, and they are not motivated to learn. Therefore, students do not understand enough about the content in English course.(2) Teachers’ Unclear Understandings of English TeachingMost college English teachers only pay attention to students’ academic performance and their ability to work out the exercise. Therefore, college English teachers usually only select articles from textbooks or reference books for reading teaching and explanation when organizing students to read. However, It is impossible to fully mobilize the enthusiasm of college students for reading on this boring way of reading teaching, and students only have a surface understanding of the article without mastering the skills and methods of reading. College English teachers also ignore the important meaning of reading. A low understanding about reading is an important reason that affects the efficiency of college English reading teaching. It makes students only passively participate in reading activities and cannot prompt students to actively understand related knowledge. As a result, teaching efficiency is low.(3) Backward Teaching Concepts and MethodsThe main purpose of English teaching is to have an inner dialogue with the author through the thinking and speculation of readers, so as to achieve emotional resonance. Whether it is an article in a college English textbook or a reading comprehension topic, it tends to allow readers to communicate with the author in depth, to achieve soul collision and emotional integration, and to further enable readers to truly feel the real emotions expressed in the article, thereby significantly promoting the reading ability of students. However, the reading concepts and reading teaching methods of most college English teachers are too traditional and backward. Teachers believe that students’ reading is only for exams. In daily teaching, teachers have been regarded as the main body of the classroom andCreativity and Innovation Vol.5 No.1 2021students have been regarded as bystanders in the classroom. At the same time, the teaching method of reading adopted by English teachers is simply to question and explain, which not only does not meet the requirements of the new curriculum reform, but also greatly dampens the enthusiasm of students for reading, and affects the cultivation of reading initiative and thinking of students.(4) The Influence of Online MediaWith the rapid development of network information technology, the information explosion occurred on network media has had a great impact on our lives and work. At the same time, due to the poor resistance of college students and the lack of good supervision by teachers and parents, attention of students is so easy to be attracted by online information. Most college students also choose to waste time in short videos or online games, which makes college English reading activities not really implemented and seriously affects the improvement of the classroom teaching efficiency of college English.2. Effective Strategies for Developing College English T eaching under the Background of New Liberal Arts(1) Teachers Who Should Play a Guiding Role1) Leading by Example and Playing an Exemplary RoleWhen students learn English, teachers usually play a super important role. Therefore, teachers should set up an excellent role for students and read extracurricular articles frequently to improve their own literary quality. In addition, teachers should also actively guide students to read extracurricular articles. While teaching students to read, they can also improve their literary literacy.2) Guiding Reading Methods of StudentsFor the teaching of English reading, teachers can teach students some reading methods and skills. These methods mainly include intensive reading, skimming and ingenious reading. In the teaching process, English teachers should correctly guide students to read articles, so that students can have a deeper understanding of the relevant content. For the reading method of ingenious reading, some students are unable to master this method due to their own limited ability, which requires teachers to actively guide them to apply the method of ingenious reading to read when teaching, and make reasonable use of some related stories or characters to help students understand the content of the article and experience the emotions expressed in the article.3) Encouraging Students to Take Reading NotesAt this stage, a common problem for college students is that students may think they have proficiently mastered the knowledge, but after a period of time, they will forget it. Therefore, it requires students to take notes carefully. For reading, itResearch on the Reform of College English Teaching under the Background of New Liberal Arts is also necessary for students to take certain notes. These notes can be a summary of the content of the article or their own experience. In the process of taking notes, it can promote students to further understand the content of the article, and it is also convenient for students to review after class, so as to further improve the learning efficiency of students in reading.(2) Stimulating the Interest of Students in ReadingInterest is the motivation for students, and reading interest can motivate college students to actively read, so that teachers can cultivate students to have good reading habits and reading methods. Therefore, the primary task for college English teachers to improve the efficiency of English reading teaching is to fully stimulate the interest of college students in reading and ignite their reading initiative and desire for knowledge, which will support students to read and think in depth. Most college students have strong curiosity and thirst for knowledge, so English teachers can fully combine their learning ability and characteristics to innovate teaching methods of reading, so as to fully mobilize college the learning initiative of students.(3) Grasping the Teaching Progress of ReadingAt this stage, in the process of teaching English reading, there is a huge amount of article teaching, and the difficulty of the article is also quite different. Due to the limited reading ability of college students, coupled with the fact that some students have a shallow understanding about the article, so that students would have many problems when learning extracurricular content. For example, for students with poor abilities, it may be super difficult to read the content of extracurricular articles, it is also not easy to understand the connotation of the article, and it will also depress these students so that they would lose confidence in the study of classics. Therefore, it is necessary for teachers to make a reasonable reading plan when teaching, guide students to arrange reading activities according to their own learning situation step by step, and choose what students are interested in as much as possible to improve their reading ability. In addition, English teachers should formulate appropriate teaching plans based on the actual situation of the students before developing English reading teaching.(4) Organizing Rich Activities of Reading TeachingDifferent students have different opinions on the same reading article, so reading notes of students would be different. Therefore, teachers can organize students to conduct selection activities of reading notes and allow students to vote for the best reading notes. In this way, students can share their own reading opinions, and it can cultivate the good reading habits of colleges students, stimulate their interests in taking reading notes often when they are reaching, improve the efficiency of actual English reading of college students, and improve their reading ability and comprehensive literacy.Creativity and Innovation Vol.5 No.1 20213. ConclusionAll in all, reading can not only greatly enrich the English knowledge of college students in the class, but also speed up the process of cultivating their good reading habits and abilities. College English teachers should attach great importance to the significant role of reading, and stimulate the reading interest of students in the class to the greatest extent through the development of effective and abundant reading activities, promote their own reading ability, promote the efficiency of college English reading teaching so that the foundation for the future study and life of students can be laid.References[1] Huang Zhang. “An Analysis of the Reform Path of College English Teaching underthe Background of the ‘Internet+’ Era” [J]. New West, 2019(12): 150+145.[2] Pei Yanqiu. “Research on the Reform and Development of College English Teach-ing Based on the ‘Internet +’ Era” [J]. News Research Guide, 2019, 10(07): 13-14. [3]Zhang Zhifan. “Analysis of the Problems and Countermeasures in College EnglishTeaching under the Background of Big Data” [J]. Think Tank Times, 2019(20):217-18.。
学校社团英语作文
School clubs are an integral part of the educational experience,offering students a chance to explore their interests,develop new skills,and foster a sense of community. Heres a detailed look at the various aspects of school clubs and their impact on students.Introduction to School ClubsSchool clubs are organized groups that focus on a specific interest or activity.They can range from academic to recreational,and are often run by students with the guidance of a faculty advisor.These clubs provide a platform for students to engage in activities they are passionate about,outside the regular curriculum.Types of School Clubs1.Academic Clubs:These include Math clubs,Science Olympiad teams,Debate clubs, and Language learning groups.They cater to students who wish to delve deeper into their academic interests.2.Arts and Literature Clubs:Drama clubs,Creative Writing groups,and Photography clubs are popular among students who have a flair for the arts.3.Sports Clubs:From traditional sports like football and basketball to more niche activities like chess or martial arts,sports clubs encourage physical fitness and teamwork.4.Social and Community Service Clubs:These clubs focus on giving back to the community,such as volunteering at local shelters or organizing charity events.5.Special Interest Clubs:Clubs like Robotics,Astronomy,or Environmental clubs cater to students with unique interests.Benefits of School Clubs1.Skill Development:Clubs provide an opportunity for students to develop and hone specific skills,whether its public speaking,leadership,or technical skills in a particular field.2.Personal Growth:Participation in clubs can boost selfconfidence,as students take on responsibilities and see the results of their efforts.working:Clubs are a great way to meet likeminded peers and form lasting friendships.4.Leadership Opportunities:Many clubs offer leadership roles,such as club president or treasurer,which can be valuable experience for future career paths.5.College Applications:Involvement in extracurricular activities,including clubs,can make a students college application stand out.Challenges of School Clubs1.Time Management:Balancing club activities with academic responsibilities can be challenging,requiring good time management skills.2.Funding:Some clubs may struggle with securing enough funding for resources orevents,which can limit their activities.3.Member Engagement:Keeping members actively involved and interested can be a challenge,especially as students interests and priorities change.How to Start a School Club1.Identify a Need or Interest:Find a gap or a shared interest among students that isnt currently being addressed by existing clubs.2.Gather Support:Rally a group of interested students to join as founding members.3.Find a Faculty Advisor:A teacher or staff member must support and guide the club.4.Write a Club Constitution:This document outlines the clubs purpose,structure,and rules.5.Apply for Recognition:Submit an application to the school administration for official recognition as a school club.ConclusionSchool clubs are a vibrant part of student life,offering a wealth of opportunities for learning,growth,and enjoyment.They enrich the educational experience by providing a space for students to pursue their passions and interests in a supportive and structured environment.Whether youre a student looking to join a club or someone interested in starting one,theres a world of possibilities waiting to be explored.。
大学值得读吗英语作文
大学值得读吗英语作文The question of whether university education is worth pursuing is a topic of much debate. Here are some points that can be considered when discussing the value of a university education1. Academic Knowledge University provides a structured environment for deep learning in a specific field. Students can gain specialized knowledge that is often necessary for professional careers.2. Critical Thinking Skills Higher education encourages students to think critically analyze complex problems and develop solutions. These skills are valuable in any profession.3. Networking Opportunities Universities offer a chance to meet and interact with peers professors and industry professionals. These connections can be beneficial for future career opportunities.4. Personal Development Living away from home and managing ones own schedule can lead to increased independence and maturity. University life exposes students to diverse cultures and ideas fostering a broader worldview.5. Career Preparation Many professions require a university degree as a prerequisite. A degree can open doors to job opportunities and higher starting salaries.6. Research Opportunities Universities often provide resources for students to engage in research projects which can lead to a deeper understanding of a subject and potential publication or presentation opportunities.7. Extracurricular Activities Participation in clubs sports and other extracurricular activities can help students develop leadership teamwork and time management skills.8. Financial Investment While the cost of university education can be high many argue that the longterm benefits in terms of career advancement and earning potential outweigh the initial investment.9. Alternative Routes Its important to acknowledge that not everyone needs a university degree to succeed. Some individuals may find success through vocational trainingentrepreneurship or other career paths.10. Lifelong Learning The pursuit of higher education can instill a love for learning that lasts a lifetime which is valuable in a rapidly changing world.In conclusion whether university education is worth it depends on individual goals financial circumstances and career aspirations. It is a personal decision that should be made after careful consideration of the potential benefits and costs.。
我的发明机器人英语作文
我的发明机器人英语作文英文回答:My invention is a humanoid robot that can assist people in various tasks, from household chores to complexscientific research. I named it "Aether," inspired by the Greek deity who personified the celestial expanse and light. Aether embodies the potential for boundless exploration and innovation.Aether is equipped with cutting-edge artificial intelligence (AI) that enables it to learn, adapt, and interact with humans in a natural and intuitive way. Its advanced sensors and actuators grant it the ability to perceive its surroundings, manipulate objects with precision, and navigate environments autonomously.Moreover, Aether is designed with a modular architecture, allowing its capabilities to be customizedand expanded through interchangeable modules. These modulescan include specialized sensors for specific tasks, additional actuators to enhance its physical capabilities,or advanced cognitive modules to augment its intelligence.The potential applications of Aether are vast. In the domestic sphere, it can assist with tasks such as cleaning, cooking, and providing companionship. In the workplace, it can streamline manufacturing processes, enhance productivity, and perform hazardous tasks. Most notably, Aether has the potential to revolutionize scientific research by automating complex experiments, analyzing vast datasets, and generating novel hypotheses.To ensure that Aether is used responsibly and ethically, I have implemented a rigorous code of conduct into its AI framework. This code governs its behavior, prevents it from harming humans or violating their rights, and ensures thatit operates in accordance with societal norms and values.Aether represents a significant step forward in thefield of robotics. Its versatility, intelligence, and modularity make it an invaluable tool for a wide range ofapplications, promising to enhance our lives, advance our scientific knowledge, and shape the future of human-robot interaction.中文回答:我的发明是一个人形机器人,它可以在各种任务中协助人们,从家务劳动到复杂的科学研究。
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Modularity and Specialized Learning in theOrganization of BehaviourJoanna Bryson and Lynn Andrea Stein1Artificial Intelligence Laboratory,MIT545Technology Square,Cambridge MA02139,USAjoanna@ and las@Abstract.Research in artificial neural networks(ANN)has provided new insights for psy-chologists,particularly in the areas of memory,perception,representation and learning.However,the types and levels of psychological modelling possible in artificial neural systems is limited by the current state of the technology.This chapter discusses mod-ularity as illuminated from research in complete agents,such as autonomous robots or virtual reality characters.We describe the sorts of modularity that have been found use-ful in agent research.We then consider the issues involved in modelling such systems neurally,particularly with respect to the implications of this work for learning and de-velopment.We conclude that such a system would be highly desirable,but currently poses serious technical challenges to thefield of ANN.We propose that in the mean time,psychologists may want to consider modelling learning in specialised hybrid sys-tems which can support both complex behaviour and neural learning.1.IntroductionResearch in artificial neural networks(ANN)has provided new insights for psychol-ogists,particularly in the areas of memory,perception,representation and learning. However,the types and levels of psychological modelling possible in artificial neu-ral systems is limited by the current state of the technology.We are only beginning to be able to model neurally many of the complex structures and interactions we know to exist in animal brains.In particular,modularity is a much-discussed feature of the brain, but we have only rudimentary models of it in neural networks.This chapter discusses modularity as illuminated by research in complete agents, such as autonomous robots or virtual reality characters.We use this research to iden-tify the sorts of modules that have been found useful in ourfield.We then describe a possible mapping between these established AI modules and the modularity present in mammalian brains.We conclude with a discussion of the implications of this work for learning,development,and the future of ANN and agent models of animal intelligence. 1LAS:also Computers and Cognition Group,Franklin W.Olin College of Engineering,1735 Great Plain Avenue,Needham,MA02492las@2.Modularity in AI and PsychologyThe extensive use of modularity in complete agents was popularised in the mid1980’s with the establishment of behaviour based artificial intelligence(BBAI).Behaviour-based AI refers to an approach inspired by Minsky[22],where many small,relatively simple elements of intelligence act in parallel,each handling its own area of expertise [3,19].In theory,these component elements are both easier to design and more plausi-ble to have evolved than a single complex monolithic system to govern all of behaviour. In the modular theory of intelligence,the apparent complexity of intelligent behaviour arises from two sources:the interactions between multiple units running in parallel,and the inherent complexity of the environment the individual units are reacting to.The behaviour-based approach generated significant advances in mobile robotics [4]and has come to dominate both thefields of robotics and virtual reality[17,27]. It has lead to a revolution in the way computation is thought about[29].Nevertheless, it has not been entirely successful.Advances in the development of humanoid agents still come disappointingly slowly.Further,there is no single dominant behaviour-based architecture that is used by even a large percentage,let alone a majority,of complete agent developers.The engineering advantage of modularity is simple:it decomposes the problem of intelligence into manageable chunks.In essence,it is a design advantage.Modularity is a form of hierarchy.Each module handles a portion of the agent’s overall problem space, leaving the complete agent with an exponentially reduced space of behaviour options to consider.However,the modular approach also introduces a number of problems.First, there is the question of how to decompose an apparently coherent intelligence into mod-ules.What state and/or behaviour belongs together,and what apart?Even more prob-lematic,once behaviours have been separated into at least semi-autonomous modules, how can overall behavioral coherence be reestablished?A modular approach is of no advantage if the problem of integrating behaviour leads to a greater problem of design than the decomposition originally avoided.From a psychological perspective,interest in modularity dates back to Freud[12], and even to Hume[16].A modular architecture is motivated not only by the inconsis-tencies of human behaviour,but also by neuroscience,which has shown a diversity of organs in the human brain.Here the same questions emerge:how is the brain modu-larised?To what extent are the modules encapsulated—that is,how strictly are they separated?Which modules communicate,and at what level of abstraction?What func-tions do the various organs perform?And how are their parallel operations coordinated intofluid,largely coherent behaviour?In the following sections,we hope to provide answers or at least hypotheses for these questions based on our work in complete agent architectures.3.Modularity in Complete Agent ArchitecturesIn this section we describe the sorts of modules that are requisite for making a complete agent function.We also show how these required modules relate to animal intelligence. To begin though,we delineate two different sorts of modularity:architectural modules vs.skill modules.3.1Types of ModularityIn thinking about the organisation of agent behaviour,we must consider two differ-ent sorts of modular decomposition.One is decomposition of generic function,where modules might include planning,vision,motor control,and such-like.The second is de-composition by task,where modules might include walking,sleeping,hunting,groom-ing and so forth.Initially,the behaviour-based revolution was about moving from the former,generic sort of modularity to the latter,task-oriented sort of modularity.Al-though the major benefits of BBAI come from the special-purpose,task-oriented sort of modularity,the experience of the last15years has shown that some generic modules are also necessary in an architecture in order for that architecture to be useful and usable.One of our hypotheses(described further below)is that this more generic modular-ity is analogous to the modularity by organ in the brain,e.g.the roles of the cerebellum or the hippocampus.We call this sort of modules architectural modules,both because in the brain it often characterised by different underlying neurological architectures, and because in agent organisation it contributes architectural features.The task-specific modules we hypothesise to be more analogous to the within-organ modularity exhibited in the brain,by neural assemblies differentiated only by physical space and connectiv-ity.We will call this sort of modules skill modules.The emphasis in this chapter will be primarily on different sorts of architectural modules,since this is the emphasis of our own research.The reader should be aware,however,that most work in BBAI concen-trates on the development of skill modules.3.2Architectural Modularity in Complete AgentsBryson[5]describes the emergence over the last15years of three sorts of architectural requirements for complete autonomous agents capable of complex,scalable behaviour. That article reviews the literature in four separate agent traditions:BBAI;the hybrid or multi-layer community,which combines behaviours with more conventional planning; the Procedural Reasoning System(PRS)/Beliefs,Desires and Intentions(BDI)com-munities,which have adapted conventional planning and representation in response to the success of BBAI and the demands of real-time,embedded systems;and the Soar /ACT-R communities,which have been working with their distributed representation cognitive agent architectures for many years.In this chapter,we will not reiterate that review,but will only describe the results.Briefly,there are three sorts of architectural modules that seem necessary.First, nearly all autonomous agents consist primarily of a system of skill modules.These are often referred to as behaviours due to BBAI.Despite their name,“behaviours”actually generate behaviour;they are not a description of expressed behaviour.There is no one-to-one correspondence between a behaviour module and an expressed behaviour.Much of expressed behaviour is supposed to emerge from the interaction of two or more skill-module behaviours operating at the same time.The second sort of architectural module performs action selection,which provides for coherent behaviour in a distributed sys-tem.Finally,because action selection generally works by focusing attention on one subset of possible behaviour,there needs also to be a dedicated environment monitor-ing module.This module switches the action-selection attention in response to salient environmental events.Nearly all autonomous agent architectures today use a modular skill structure.They incorporate a set of primitive behaviours that no other part of the system needs to under-stand the workings of.This reflects the combinatorial advantage of modularity referred to in the introduction.It comes at a cost of lessfine-grained control and the inefficien-cies of not being able to combine the outputs of related actions or motions.But for a resource-constrained agent working in a dynamic,real-time environment where re-sponses must be quick and appropriate,the advantage of being able to quickly activate pre-compiled skills outweighs these sorts of costs.Some researchers try to reduce some of the complexity of coordinating skill mod-ules by using homogeneous behaviour representations or coordinated output formats for all the modules(see for examples Arkin[1]and Tyrrell[30]respectively).We feel these strategies overconstrain the sorts of computation and representation in a skill module. Skill modules should contain not only motor actions,but also whatever perceptual skills are necessary in order to support them.Perception is not just sensing.Sensory stimuli are often ambiguous and often require both recent context and longer-term experience and expectations to discriminate.The state needed to learn or tune skills,or to disam-biguate or categorise the perception,should also be a part of the skill module.Actions may also vary significantly depending on context,but a designer may want to encap-sulate all these expressions as a single behaviour for simplicity.For this reason,we prefer using objects specified in object-oriented programming languages to represent skill modules.This representation of skill modules has advantages for two reasons.From an engi-neering perspective,it allows for the behaviour decomposition problem to be addressed with techniques similar to those developed for object decomposition(e.g[9])and al-lows us to quickly develop more powerful,complex behaviour[6].From a cognitive modelling perspective,this level of abstraction is more closely analogous to the level of description usually used for ascribing functions to cortical areas.Although early BBAI eschewed variable state,in general the notion of empowered,perceiving semi-autonomous behaviours is more in keeping with this work than the trend in hybrid and BDI architectures to making the skill modules into simple motor primitives.It is also very like the recent contributions of the multi-agent systems(MAS)community[31].The next architectural module is hierarchically structured plans for action selection.“Action selection”is the term applied to the ongoing problem of determining exactly what an agent is going to do next.The BBAI literature often refers to this problem as “behaviour arbitration”,in MAS it is called“agent coordination”.When all behaviours are running in parallel,each may have an action it is currently attempting to express.If these conflict,some method of coordination must maintain the coherence of the com-plete agent’s behaviour.Plans in the context of agent action selection are structures which indicate,given a particular environmental context and decision history,what to do next.BBAI originally strongly resisted the use of plan-like structures for coordination,because they were felt to lose most of the advantages of modularity by imposing a form of centralised control.However,these systems proved useful not only for coordination,but also as simple memory.A system using plans to coordinate behaviour does not need complexor perfectly ordered episodic memory in order to disambiguate where it is in a multi-step plan,even if the consequences of its previous actions are not present in its environment.For example,consider,a robot tidying an office.If it has afixed order for tidying drawers it neither needs to repeatedly inspect closed drawers it had already tidied,nor to remember the complete list of drawers already visited each time it selects the next one.It only needs to remember its agenda,and its current place in its agenda.Notice the agenda does not need to specify any details about how a drawer is cleaned.The drawer cleaning behaviour is free to chose a methodology appropriate to its perceptions,or to determine whether a drawer is already“clean enough.”Although such structures for supporting action selection are referred to as plans,this does not necessarily imply that they are created by planning,at least not by the agent. Most complete agents exploit plans provided by their designers,rather than engaging in the slow and unreliable constructive planning process.Choosing what to do next this way,without deliberation,is often called reactive planning.When plan-like structures are provided to facilitate this process,they are referred to as reactive plans.Hierarchical structures for action selection allow for the focus of attention on a par-ticular set of behaviours that are likely to be applicable in a particular circumstance.The hierarchies are parsed by the recognition of circumstance,and can be reparsed arbitrar-ily frequently in order to ensure the applicability of current behaviour.This observation leads to the third architectural module found in all successful agent architectures:a mechanism for monitoring the environment and realizing that the agent should attend to new goals.This sort of system is sometimes referred to as an alarm system(e.g.[28]).Having a parallel system is necessitated by hierarchical control:any agent in a dynamic environment that may have its attention focussed on a particular task needs a system to guarantee that it notices salient events in the environment.Otherwise,the agent may overlook both dangers and opportunities.The alarm system must necessar-ily be relatively simple,requiring no cognitive overhead that would distract from the primary task.It is usually a case of pattern matching,of recognising salient indicators in the environment and then switching cognitive attention to analysing and coping with such situations.3.3Equivalent Modularity in Animal BrainsIn summary of the last section,complete agent architectures have converged on three sorts of architectural modules for supporting complex,dynamic behaviour.These are a system of skill modules,structured action selection,and an environment monitoring system.If such an organisation is necessary or at least very useful for controlling intel-ligent agents,then it is also likely to be present in animals,since they have evolved to face similar problems of information management.In this section we speculate about what the analogous modules might be.First,the skill modules we believe are reflected in within-organ modularity in the brain.This is not to imply that they are represented only within one organ or region: many skills necessarily combine vertically a large number of brain areas and organs,for example the retinas,visual cortex,associative cortices,motor pre-planning and motor coordination.To some extent,each of these areas is architecturally specialised,but thecombination of a particular ensemble of simultaneous activations across these structures might model the various skill sets modularised in agent architectures.Next,Prescott et al.[24]postulate that the basal ganglia is the architectural module responsible for action selection(see also[21]).These researchers focus primarily on the problem of action selection as behaviour arbitration,but the basal system is also well integrated with some of the mid-brain systems that have been implicated in species-typical action patterns as well as the cortical systems which might hold the perceptual skill modules required to discriminate context.Finally,the behaviour of the alert system is analogous to behaviour attributed to the limbic system.In particular,the amygdala has been implicated in learning to recognise and attend to salient situations[8].This attention takes the form of emotional responses, which are characterised by the selective activation of appropriate behaviours and expec-tations.Thus it is plausible,if far from proven,that the sorts of modularity used in com-plete autonomous agents are also present in animals and humans.This reenforces our proposal that the agent platform could be useful for psychological modelling.4.Learning in Behaviour Oriented ArchitecturesA particular modular organisation provides structure not only for how an intelligence operates in particular situations,but also for how it can learn.We assume that learning happens within modules,not across or outside them.So,for the organisation of mod-ules described in the previous section,there are only certain places learning can take place.There can be specialised or perceptual learning within the skill modules.There can be learning of new skill modules within the architectural module of skill modules. There can be the learning of new reactive plans within the action selection module,and there can be learning of selection rules for priorities and alarms.Notice that the sorts of perceptual learning that takes place in skill-modules can also affect the execution of re-active plans and of attention switching.In our model,learning new categories,both new discriminations and new generalisations,is the sort of perceptual learning that should take place in a skill module.Not all complete agent architectures perform learning in this way.Some which are more closely aligned traditional planning maintain a single database of“beliefs”[15]. Production-based agents[18]often have both a database of beliefs and a database of productions:if-then rules governing intelligent control.These productions,analogous to behaviours in their modularity,are not as complex as the sorts of skill modules we have been describing.For the remainder of this chapter,we will be emphasising complete agent architectures that are behaviour oriented.Behaviour-oriented systems differ from being strictly behaviour-based because they have structured action selection,but are otherwise near to traditional BBAI systems in their emphasis on relatively autonomous behaviours capable of perception and action(see Figure1).Agents tend to be created for particular environments and tasks;in other words they are niche specific.Consequently,the kinds of things they are likely to need to learn can generally be determined in advance.This is a currently popular view of animal learn-ing[13,25],and we have made it central to our methodology for developing behavioura5Figure1:Behaviour-oriented systems have multiple,semi-autonomous skill modules or be-haviours(b1...)which generate actions(a1...)based on their own perception(indicated by the eye icon).Actions which affect state outside their generating behaviour,whether internal to the agent or external,are generally subject to arbitration by an action selection(AS)system. oriented agents,which we call behaviour oriented design(BOD)[6].We determine the modular decomposition for a set of skills around the kinds of perception and memory those skills need to operate appropriately.Thus each skill module contains specialised representations and perception and action routines for maintaining those representa-tions,as well as control for the skilled actions that the agent applies to its environment.The second most common form of learning in complete agents is the learning of new reactive plans.This is usually done in one of two ways,either by reasoning or planning a new plan(e.g.[2,14]),or more recently by social learning such as imitation or receiving instruction(e.g.[10,26]).However,in practice,a surprisingly large number of agents use plans programmed by their designers.So far,this is still the fastest and most reliable way to get appropriate behaviour from an agent.5.Learning New BehavioursIn our earlier discussion of skill modules,we claimed that behaviour oriented design requires the use of complex algorithms and specialised representations,and that mod-ules are therefore better represented in object oriented languages than in current ANN. However,there is at least one reason to favour an ANN representation of skill modules. That is the problem of designing an agent that can learn or develop new skill modules. This is clearly desirable,and has been the focus of significant research(see[10]for a recent example and review.)However,to date,most efforts on these lines would qualify as specialised learning within a single skill module/representation system from the perspective of behaviour oriented design.The reason that we would like to be able to represent behaviours in terms of ANN is as follows.Consider Figure2.In thisfigure,representation of the skill modules has been split into two functional modules:the Behaviour Long Term Memory(BLTM)and the Working Memory(WM).The working memory allows for rapid,short term changes not only for perceptual memory,but also in the representation of the behaviours.The BLTM provides a relatively stable reference source for how these modules should appear whenFigure2:A system capable of learning behaviours must1)represent them on a common sub-strate and2)allow them to be modified.Here behaviours are represented in a special long term memory(BLTM)and in a plastic working memory(WM)where they can be modified.During consolidation(dashed lines)modifications may either alter the original behaviours or create new ones.activated.Skill representations might be modified due to particular circumstances,such as compensating for tiredness or high wind,or responding to a novel situation such as using chopsticks on slippery rice noodles for thefirst time.In this model,the adjustments made in plastic,short term memory also affect the long term memory.This sort of dual-or multi-rate learning is receiving a good deal of attention in ANN currently(see[7,11,20]).Depending on long term experience,we would like this consolidation to have two possible effects.Let’s imagine that b2has been modified in working memory in order to provide an appropriate expression of a2.If the same modifications of b2prove useful in the near future,then they will be present for consolidation for a protracted period,and likely to effect the permanent representation of b2.However,if the modifications are only sometimes applicable,we would like a new behaviour b2 to become established.This process should also trigger perceptual learning,so that the two behaviours can discriminate their appropriate context for the purpose of action selection.Also b2and b2 would now be free to further specialise away from each other.6.Conclusions and Future DirectionsIn this chapter we have shown that complete agents can provide higher-level AI models for psychologically important concepts such as modularity and specialised learning.We have also described the sorts of systems that are the current state-of-the-art in complete agent architectures.We have shown that using ANN to represent at least some parts of a complete agent might be highly desirable,but unfortunately we have also argued that the complexity of the algorithms and the specialised representations are not yet met in current models of ANN modularity(e.g.[23]).On the other hand,we believe that combining research in these twofields might be a highly useful plete agent researchers are already experimentingwith ANN for learning and simple control,but most such systems are not yet ad-vanced enough to be interesting to psychologists.However,the psychologically in-teresting ANN systems currently under development such as those described in this volume might be furthered by embedding them in a complete agent.In this way,con-ventional programming can be used to provide for appropriate experimental platforms to test such systems.A complete agent can provide realistic inputs,and test outputs in realistic settings.Thus,we hope to see a further uniting of these twofields in the future. 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