Acoustic wave biosensor for the detection and iden
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专利名称：Acoustic wave biosensor for the detection
and identification of characteristic signaling
molecules in a biological medium
发明人：Peter J. Edmonson,William D. Hunt,Desmond
D. Stubbs
申请号：US12636252
申请日：20091211
公开号：US08420382B2
公开日：
20130416
专利内容由知识产权出版社提供
专利附图：
摘要：An acoustic wave biosensor comprises a plurality of spaced apart electrodes
disposed on a substrate of piezoelectric material and having a biolayer matched to a specific type of autoinducer signaling molecule to be detected. The biolayer comprises a layer of heterobifunctional molecules disposed on the electrodes and on the piezoelectric material between the electrodes, and a plurality of bioreceptor molecules which bind exclusively with the specific type of autoinducer signaling molecule to be detected. The bioreceptor molecules are supported by the layer of heterobifunctional molecules, and a hydrogel layer surrounds the bioreceptor molecules to support a three-dimensional structure thereof. The bioreceptor molecules can bind with the specific type of autoinducer signaling molecule to be detected, and the biolayer is reactive thereto such that corresponding autoinducer signaling molecules bind to the biolayer and detectably vary acoustic characteristics of the acoustic wave biosensor.
申请人：Peter J. Edmonson,William D. Hunt,Desmond D. Stubbs
地址：Hamilton CA,Decatur GA US,Riverdale GA US
国籍：CA,US,US
代理机构：Carey Rodriguez Greenberg O'Keefe, LLP
代理人：Steven M. Greenberg
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