Tgf-beta antagonists combined with renin-angiotens
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专利名称:Tgf-beta antagonists combined with renin-angiotensin-aldosteron-system antagonists
for treating renal insufficiency
发明人:Steven Ledbetter,Ariela Benigni,Giuseppe Remuzzi
申请号:US10553595
申请日:20040430
公开号:US20060286105A1
公开日:
20061221
专利内容由知识产权出版社提供
摘要:The disclosure provides methods for treating, preventing, and reducing risk of occurrence of renal insufficiency in mammals. The disclosed methods include administering to a subject susceptible to, or afflicted with, renal disorder therapeutically effective amounts of a TGF-β antagonist and a renin-angiotensin-aldosterone system (RAAS) antagonist so as to maintain desirable levels of renal function. The populations treated by the methods of the invention include but are not limited to patients suffering or at risk for the development of renal insufficiency, such as those afflicted with type I or type II diabetes, hypertension, (auto)immune disease, systemic fibrosis, etc.
申请人:Steven Ledbetter,Ariela Benigni,Giuseppe Remuzzi
地址:Westborough MA US,Bergamo IT,Bergamo IT
国籍:US,IT,IT
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