糖代谢异常和糖尿病患者血清CA19-9的观察

糖代谢异常和糖尿病患者血清CA19-9的观察
杨文;黄海燕
【期刊名称】《实用老年医学》
【年(卷),期】2013(027)001
【摘要】目的探讨血清CA19-9水平在糖代谢异常和糖尿病患者中的变化. 方法对34例糖尿病、32例糖代谢异常和77例正常对照组患者年龄、体质量指数(BMI)、血清CA19-9、空腹血糖(FBG)、总胆固醇(TC)、三酰甘油(TG)、肌酐(CRE)和尿素氮(BUN)进行对比观察. 结果糖尿病组和糖代谢异常、正常对照组之间比较血清CA19-9明显升高(P＜0.01).多因素linear regression分析发现在糖代谢异常组TG和血糖是CA19-9的相关因子(P＜0.05或P＜0.01),在糖尿病组TC和血糖是CA19-9的相关因子(P＜0.05或P＜0.01). 结论糖尿病患者血清
CA19-9升高,可能提示糖尿病患者具有胰腺外分泌功能受损.%Objective To study the changes of CA19-9 in patients with diabetes mellitus and impaired glucose metabolism. Methods Age, body mass index (BMI) ,
CA19-9, fasting blood glucose, total plasma cholesterol, plasma triglyceride, plasma creatinine concentration and blood urinary nitrogen were observed in 34 cases with diabetes mellitus, 32 cases with impaired fasting glucose and 77 healthy controls. Results CA19-9 were significantly higher among the three groups ( P < 0.01). With linear regression analysis, fasting blood glucose and plasma triglyceride were identified as significant and independent risk factors for CA19-9 (P <0. 01 or P <0. 05) in impaired glucose metabolism group and fasting blood glucose and total plasma
cholesterol were identified as significant and independent risk factors for CA19-9 (P < 0. 01 or P <0. 05) in diabetes mellitus group. Conclusions The CA19-9 is increased in patients with diabetes mellitus. The elevations of CA 19-9 in diabetics should be considered as an indication of exocrine pancreatic dysfunction.
【总页数】3页(P26-28)
【作者】杨文;黄海燕
【作者单位】100048北京市,中国人民解放军海军总医院干部病房综合科;100048北京市,中国人民解放军海军总医院干部病房综合科
【正文语种】中文
【中图分类】R587.1
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