Chinese medicine for treatment of chronic hepatitis B
Chinese Medicine
Traditional Chinese Medicine (TCM,中国传统医学) is also well-known as Chinese Medicine(中医，zhōngyī). Based on the theory of yin-yang(阴阳)and five elements(五行), it also absorbs experience that how ancient Chinese people fight with disease and then develops into a broad range of medical care ways, including various forms of Chinese Herbal Medicine(草药cǎoyào), Cupping(拔火罐báhuǒguàn), GuaSha(刮痧guāshā),Acupuncture(针灸zhēnjiǔ),Moxibustion(艾灸àijiǔ), Massage(推拿tuīná按摩ànmó), pediluvium (足浴), Qigong(气功qìgōng)and Dietary therapy(食疗shíliáo).Traditional Chinese Medicine (TCM) has a huge influence throughout East Asia since ancient time and now also in the western world. Generally speaking, Traditional Chinese Medicine (TCM) can be divided into two main parts: Han medicine and ethnomedicine. The former one refers to a medicinal science which is created by the Han People; The latter one includes Zang Medicine(藏医Tibetan Medicine), Meng Medicine(蒙医Mongolian Medicine), Miao Medicine(苗医) and other ethnic medicine. However, when we mention Traditional Chinese Medicine or Chinese Medicine, most of the time, we just mean Han medicine.Traditional Chinese Medicine treats human body as an entity of qi(气), shape(形) and spirit(神). Then through four diagnostic methods to search for the cause of disease and analyze the change of the zang-fu, jingluo,qi,blood(血) and jinye, after that, a disease name will come out and suitable medical care way will be adopted.Important Terms and Concepts in Traditional Chinese Medicineyin-yang: 阴阳,yīnyáng, the concepts of yin and yang came from ancient Chinese people’s views of nature. In old times, they found many nature phenomenon in an against or conjoint relationship, for instance, heaven and earth, the sun and the moon, day and night, male and female,inside and outside, downward and upward, etc, so they drew a conclusion in a philosophy way----yin and yang, which was mentioned in Yi Zhuan and Dao De Jing of Laozi in the spring and autumn period and infiltrated nearly every aspect of Chinese traditional culture. Hence, yin and yang also extends to the various body functions: exterior and interior, cold and heat, vacuity and excess. The balance of yin and yang is a symbol of health.five phasesfive phases or five elements: 五行, wǔ xíng, is a view of matter in ancient China and used very often in Chinese philosophy ,Chinese medicine and divination. In old times, Chinese people thought nature was formed by five elements: metal, wood, water, fire and earth. With ups and downs of five elements, nature changed and people’s fates also were influenced. Talking about Chinese medicine, five elements indicates different organs. Because of the mutual generation and restriction relation between five elements, Chinese doctors believed one organ’s pathology would have great effect on other organs.Four Diagnostic Methods(四诊)----four must steps in Chinese MedicineWang: 望,wàng, to observe a patient’s growth, complexi on, coating on the tongue, expression and so on;Wen: 闻,wén, to listen to a patient’s voice, cough, breath and smell his halitosis and body odor;Wen: 问,wèn, to ask a patient about his symptom and medical history;Qie: 切,qiē, to feel a patient’s pulse and touch his abdomen to see whether there is a lump or not.zang-fu: 脏腑,zàngfǔ, a generic term for the vital organs of a human body in Chinese Medicine, they are different from anatomical organs. Ancient Chinese people divide internal organs into Fivezang(五脏)和Sixfu(六腑). Fivezang includes Heart, liver, Spleen, Lung and Kidney which have a function to store qi and jinye. While Sixfu refers to Gallbladder, Stomach, Large Intestine, Small Intestine, Urinary Bladder and Sanjiao which have essential functions consisting of transmitting and digesting substances like waste, food, etc.jingluo: 经络, jīng-luò, jīng are the meridians and luò are subsidiary channels. In Chinese Medicine, jīng-luò is not only to connect the interior of the body to the surface but also the channels for transporting qi and xue. The study of jīng-luò is a significant foundation for acupuncture and massage. According to the difference of size and shade, TCM identifies twelve “regular"(十二经脉), eight "extraordinary" meridians(奇经八脉) and fifteencollaterals(十五络脉).qi: 气,Qì, is a very common concept in Chinese philosophy, Chinese Fengshui, Taoism and Chinese Medicine. It is believed to be the basic substance to form a body and the most elementary energy for maintaining vital movement.TCM uses different names for identifying qi that runs inside of the blood vessels or circulates in the meridians. And the most important qi is “principal qi”(元气yuánqì )or “true qi”(真气，zhēnqì) that held by zangfu.jinye: 津液,jīnyè, bodily fluids, have functions of nurturing and moisturizing the different structures of the body, producing blood and harmonizing Yin and Yang. According to the character, distribution and function of bodily fluids, TCM divides them into Jin and Ye.If you are a fan of Chinese Kungfu, you will be familiar with these words, such as “principal qi”(元气yuánqì )or “true qi”(真气，zhēnqì), and RenduErmai(任督二脉,rèndūèr mài )---- two major channels of eight"extraordinary" meridians(奇经八脉).History of Traditional Chinese MedicineTraditional Chinese Medicine is a treasure that many Chinese people devote themselves into the development of TCM. As a resulit, many classics of China Medicine and famous doctors appeared in history.Tracing the source of Traditional Chinese Medicine, we found that it emerged in primitive society and the theories of Traditional Chinese Medicine were formed basically in the spring and autumn and warring states periods. At that time, anatomy arose; four diagnostic methods, cure ways like stone needles, acupuncture and moxibustion were adopted.In the Western Han Dynasty, medical professionals appeared;In the Eastern Han Dynasty, famous medical scientist Zhang Zhongjing summed up eight therapeutic methods; Hua Tuo got high reputation because of powder for anesthesia and created body building exercise----five-animal boxing. In the Tang Dynasty, Sun Simiao summarized forefathers’ theories and collected 5000 prescriptions. After Tang Dynasty, works about Traditional Chinese Medicine were spread to Koryo, Japan, Central Asia, Western Asia, etc. In the Song Dynasty, the central government set Hanlin medical school and the branches of medicine is almost completed. And the most important thing is, tújīng, as the first unified acupuncture point book was published. In the late Ming Dynasty, Li Shizhen wrote the book Compendium of MateriaMedica. Meanwhile, Meng Medicine and Zang Medicine were influenced by Han medicine. From the end of Qing Dynasty, modern medicine (Western medicine) were spread to China and impacted the development of Chinese Medicine.The Traditional Chinese MedicineThe Modern Chinese Medicine Shop ShopIn the modern time, Traditional Chinese Medicine has returned. When Sars swept China in 2003, Traditional Chinese Medicine was proved to be effective in precaution. And when H1N1 Flu came out in 2009, Chinese doctors used Chinese Remedy of Herbal Medicine to treat H1N1 Flu (Swine Flu).Clinical cases even stated clearly that Traditional Chinese Medicine had good function on the treatment of cancer. Of course, some times, patients need TCM and Western medicine work together.Chinese Medicine for disease prevention and treatment during trip。
中西医治疗慢性重型肝炎研究进展_范媛媛
222第15卷 第9期 2013 年 9 月辽宁中医药大学学报JOURNAL OF LIAONING UNIVERSITY OF TCMVol. 15 No. 9 Sep .，2013慢性重型肝炎（Chronic severe hepatitis，CSH）病变的实质是大块性（全小叶）或亚大块性新鲜的肝实质坏死，即脏之形体实质损坏。
主要是在慢性肝病（包括慢性肝炎病毒携带状态、轻到重度慢性肝炎和肝硬化）的基础上由于肝细胞大量坏死而导致严重肝功能损害的一种疾病。
其病情重、进展快、治疗难度大，病死率高达70.0%以上[1]。
我国慢性乙型重型肝炎死亡率占全部CSH 的96.8%[2]，大都是由慢性乙型肝炎或乙肝后肝硬化发展而来，预后差，其各种并发症是导致病死率居高不下的重要原因。
目前临床上对于CSH 的治疗方法很多，但尚无明确的统一标准，主要包括以下几个方面。
1 西医治疗主要包括基础对症支持治疗，免疫调节治疗，抗病毒治疗及其他疗法。
1.1 基础对症支持治疗CSH 病变的实质是肝细胞大量坏死，以肝功能衰竭为主要临床表现，根据2006年中华医学会感染病学分会肝衰竭与人工肝学组、中华医学会肝病学分会重型肝病与人工肝学组制定的《肝衰竭诊疗指南》：CSH 临床上以血清总胆红素（TBIL）>171μmol/L（大于正常10倍）或每日上升≥17.1 μmol/L，有出血倾向，凝血酶原活动度（PTA）<40%为特征，临床表现主要为重度黄疸、黄疸进行性上升、极度乏力、极度食欲减退、恶心呕吐、腹水，甚则出血、肝昏迷。
因此治疗CSH 首先应运用促进肝细胞生长的药物，使得大量坏死的肝细胞得以尽快再生，目前临床上运用的药物主要有促肝细胞生长因子（HGF）、保肝解毒药物（还原型谷胱甘肽、阿思欣泰、多烯磷脂酰胆碱）、保肝退黄药物（思美泰）等。
其次应积极对症治疗，包括纠正低蛋白血症，补充白蛋白或新鲜血浆，并酌情补充凝血因子，缩短凝血酶原时间，并注意纠正水电解质及酸碱平衡紊乱，预防感染。
中国中医英文介绍
中国中医英文介绍Traditional Chinese Medicine ("TCM") is an integral part of Chinese culture. It hasmade great contributions to the prosperity of China. Today both of TCM and western medicine are being used in providing medical and health services in China. TCM, with itsunique diagnostic methods, systematic approach, abundant historical literature and materials, has attracted many attentions from the international community. TCM is wellrecognized for its remarkable effectiveness in off setting the side effect caused by the toxicand chemical treatment of cancer cases in the western medical system.In China, TCM is under the administration of State Administration of TCM and Pharmacology. TCM and its development are regulated. National strategies, law and regulations governing TCM are now in place to guide and promote the research and development in this promising industry.TCM is defined as a medical science governing the theory and practice of traditionalChinese medicine. It includes Chinese medication, pharmacology/herbalogy, acupuncture, massage and Qigong.Hospitals in China are classified as specialized in western medical system, TCM orboth. TCM is now available to 75% of the areas in China. TCM has been very effective inthe treatment of diseases such as cardio-cerebro-vascular, immunogenic, tumors, bone fracture, etc. Scientific research and clinic experiments in TCM are continuously progressing. Successes have been made in many of the areas such as in circulating pathsof meridians; in Zheng-syndrome, in diagnostic indexes; in therapeutic principles, in healing emergency patients with shock, acute DIC, acute myocardial infarction and acuterenal failure. For treatment of bone fracture, method is adopted based on the theory of combination of mobilization and immobilization. Non-antibacterial compound prescriptions are used successfully in treatment of bacterial infection. In treatment of cancers, Fuzheng Guben compound prescriptions, though devoid of inhibitory effects oncancer cells, could cause the shrink of the mass of cancer. TCM provides a non-surgicalapproach to the treatment of acute abdomen.CuppingCupping the source ofCupping therapy is a valuable heritage of Chinese medicine, one in Chinese Han people to use a long time. Ge Hong Jin Dynasty medical scientist with the "elbow back-up emergency party" where there are angle method documented. The so-called angle methodis the use of hollowing out of the horns to pull abscess aspiration of foreign governing methods. Wang Tao of the Tang Dynasty "Taiwan Miyao," also describes the use of bamboo cupping to cure, such as in the text, said: "... ... take three fingers Daqing bamboo,long Cunban, a left section, no section of the first cut so thin like swords, cook the cheeseNumber of boiling, and heat out of cartridges, ink points according to the cage, a long time to break the corner cutter bombs, but also re-Kok, cook cheese, when a yellow andwhite Chishui, sub-a pus out, worm out there who count so Kok, so that out of evil thingsto do, is that is, except, when the head is also out as light. "angle from the above describedmethod and system of green bamboo cupping of view, China's Jin, Tang Cupping of theera has long been popular.Cupping a comfortable pull Bingti"Cupping" is the private sector is commonly known as cupping therapy, also knownas "pulling pipes" or "suction tube." It is the air tank with heat to exclude the use of negative pressure so that sorption in the skin, causing bleeding as a treatment method ofthe phenomenon. This treatment can be by cold dampness, dredge the meridians, dispelstasis, qi and blood circulation, reduces swelling, pain, diarrhea fever Sida has to adjustthe body's yin and yang balance, lifting of fatigue, enhance physical function to achievethe rousing, cure The purpose of the disease. Therefore, many diseases can be treated with cupping therapy. For example: middle-aged, bones and muscles ache common, according to the interpretation of traditional Chinese medicine mostly rheumatoid Suchis Life. Cupping Guankou cover their time in the affected area, you can slowly suck themoisture out of lesions, while promoting local blood circulation, to relieve pain, restorefunction, and consequently treatment of rheumatism, "Bi Tong" bones bitterness and sodoes not apply.Cupping can do it because of gas-blood circulation, expelling wind and cold-dispelling, reduces swelling, pain, so the back muscle strain, lumbar disc herniationhave a certain therapeutic effect. Dr. Lulu's briefing, fire can also be used in the body acupuncture points, the treatment of headache, dizziness, faces badly bruised, coughing, wheezing, abdominal pain and other illnesses, and more than fire can be implemented atthe same timeCupping Traditional Chinese Medicine on the principle:Chinese medicine, cupping can be opened to vent Cou science, rousing. Disease is caused by pathogenic factors of yin and yang of the body Piansheng partial decline, thebody movements of qi disorders, internal organs caused by blood disorders. When the body is affected by wind, cold, summer heat, wet, dry, fire, poison, trauma or internal injuries invasion blog, you can lead to dysfunctional organs, resulting in pathological product, such as congestion, qi, phlegm, Sushi, water turbid, Xiehuo and so on, these pathological product is pathogenic factors, through the meridians and acupoints to go channeling the body, against the indiscriminate air-stranded organs; deposition resistance in turn, eventually lead to all kinds of illnesses. Cupping resulting vacuum hasa strong pull of the suction force, pulling the suction force acting on the meridian points,it can be to open pores and make skin absorption congestion, so that the body's pathological product from the skin pores to suck out of the body, so that able to dredgethe meridian qi and blood, so that organs function to be adjusted to achieve the purposeof combating the disease. Chinese medicine, cupping can dredge meridians, adjust blood. Meridians have "blood-line, business yin and yang, Confucianism bones, Lee joint," the physiological functions, such as the meridians are not impeded General through the air,blood stagnation line, there may be skin, flesh, tendons, veins and joints dystrophy andatrophy, adverse , or blood do not wing, Six Hollow Organs were not delivered and so on.By cupping the skin, pores, meridians, acupuncture points of the suction pull the role ofanger can lead battalion Wei lost before a cloth, agitation meridians qi, Ru Yang organstissues and organs, very inviting fur, while virtual decline of the organs function to beexcited, smooth meridian, adjust the body's yin and yang balance so that blood can be adjusted so as to achieve fitness illnesses Liaoji purposes.Western medicine on the principle of cuppingModern medicine, cupping treatment tank role in the formation of negative pressure,so that local capillary congestion and even rupture, rupture of red blood cells, skin congestion, there own hemolysis, then produce a histamine histamine and classes of substances, with the body fluids of weeks Stream body, to stimulate the various organs, to enhance its functional activity, can improve the body's resistance. Modern medicine, cupping negative pressure stimulus, enabling the expansion of local blood vessels, promote blood circulation, improve congestive state, strengthen the metabolism, changesin nutritional status of local organizations to enhance the permeability of blood vessel wall and leukocyte phagocytic activity, enhance the body's physical and human immunity.Modern medicine, cupping pressure on local parts of the suction pull, can speed up theblood and lymph circulation, promote gastrointestinal peristalsis, improving digestive function and promote. Speed up the muscle and internal organs on the Elimination of metabolite excretion.Cupping cans left spot, as well as the significance of colorCommon tank spots are flushing, purple or purplish black ecchymosis, small point-like purple rash, but also often accompanied by varying degrees of heat pain. Thesechanges in the skin are cupping therapy effect, and sustainable one to several days.Cupping, the tank spot, such as noticeable blisters, edema, and water vapor-like, indicating that patients with wet wet Sheng or because of the illness experience.Sometimes, after the blisters Secheng drawing blood red or black and red, indicatingthat the wet long illness folder pathological response to stasis.Cans dark red spot appears, Zihei or Dan dehydration phenomena, the micro-touchpain, and those who see the body heat, indicating that patients have a heat-toxin syndrome.Such as cans purple or purplish black spot appears, no Dan stasis and heat phenomena, indicating that there is congestion in patients with disease.Can spot-free skin color changes, do not touch the warm, multi-show patients Deficiency Syndrome.In case of micro-itching spot cans or there Piven, the wind's disease patients had more than that.Generally disease-free more than those who had no significant change in tank spot.About Our Massage ServicesMassage is the practice of soft tissue manipulation. It involves acting on the body and manipulating it with pressure. The masseur may use his hands, fingers, elbows, forearm,and even his feet to manipulate the tissue. Target tissues may include muscles, tendons, ligaments, skin, joints, connective tissue, lymphatic vessels, or organs of thegastrointestinal system. In China, massage is widely practiced and taught in hospitals andmedical schools and is an essential part of primary healthcare.At Sam’s Massage Center, clients lie fully clothed on a massage table. If cupping on scraping treatments are requested, the area to be treated is exposed. Full body oilmassage requires partial disrobing. Blankets are available to keep the client warm shouldthe client feel cold during the massage.Chinese Medical Massage (Tui Na)Chinese Medical Massage is good if you are experiencing pain in one or more parts ofyour body, such as neck pain, lower back pain, shoulder pain, slipped discs, sciatic nervepain, stomach problems (such as indigestion, heartburn, or digestive problems), orintestinal problems. The masseur can give you an all-over massage and focus on specificareas with pain or do a treatment on the affected area. The masseur uses shiatsu, or acupressure, to relieve pain. The masseur may use his thumbs, palms, elbow, and forearmwhile performing the massage.Sam’s Therapeutic MassageSam’s Therapeutic Massage is a deep tissue, all-over body massage. The masseur uses his thumbs to apply pressure to pressure points in the body, then releases his thumb fromthe point. You may experience some pain during the application of pressure, but the endresult is that you will feel relief when the pressure is released.Deep tissue massage is designed to relieve severe tension in the muscles and connective tissue. This type of massage focuses on the muscles located below the surface of the top muscles. Deep tissue massage is recommended for clients who experience constant pain,are involved in heavy physical activity, or have sustained a physical injury.Special Woman’s MassageOur special woman’s massage concentrates on areas of special concern for woman. The massage consists of a medical massage with attention paid to the pelvic area and themuscles above the breasts.Oil MassageWe use aromatic essential oils and massage techniques similar to Swedish massage. Oil massage consists of broad, circular strokes with no pressure point or deep tissue massage techniques. Oil massage is soothing and a great way to feel relaxed and refreshed. We especially recommend oil massage if you have been having difficulty sleeping.Foot MassageOur foot massage is different from traditional Chinese foot massage in that we performthe massage while the client is recumbent. We do not soak the feet in water but apply hot,wet towels to the feet before starting the massage. We use an emollient cream to softenand moisturize the feet during the massage. The masseur uses reflexology techniques to pinpoint problem areas in your body and improve your health.。
高效液相色谱串联质谱法测定当归芍药散提取物和含药血清中3种活性成分含量
高效液相色谱串联质谱法测定当归芍药散提取物和含药血清中3种活性成分含量宋祯彦1，何攀2，李富周1，贺春香1，余婧萍1，成绍武11.中西医结合心脑疾病防治湖南省重点实验室，湖南中医药大学，湖南长沙 410208；2.中南粮油食品科学研究院有限公司，湖南粮食集团有限责任公司，湖南长沙 410005摘要：目的 建立测定当归芍药散提取物和含药血清中3种活性成分含量的高效液相色谱串联质谱方法。
方法 药物提取物样品经甲醇-水（1∶1，V/V）溶液溶解、离心、净化后过0.45 μm滤膜，血清样品适当稀释、过膜后用高效液相色谱串联质谱法测定。
色谱柱为Agilent Poroshell 120 EC-C18（100 mm×2.1 mm，2.7 μm），茯苓酸流动相为乙腈-0.5 mmol/L乙酸铵水溶液（9∶1，V/V），阿魏酸和芍药苷以乙腈-5 mmol/L乙酸铵水溶液为流动相梯度洗脱，流速0.4 mL/min，柱温35 ℃，进样量5 μL，采用电喷雾离子源，负离子模式，干燥气温度350 ℃，干燥气流速12 L/min，检测方式为多反应监测。
结果 当归芍药散中阿魏酸、芍药苷和茯苓酸分别在0.1～20.0 μg/mL、1～100 μg/mL、0.1～20.0 μg/mL范围内线性关系良好，加样回收率高，重复性好。
当归芍药散提取物中阿魏酸、芍药苷和茯苓酸含量分别为（127.6±14.9）μg/g、（6081.8±468.0）μg/g和（14.7±0.75）μg/g，当归芍药散含药血清中阿魏酸和芍药苷含量分别为（0.026±0.004）μg/g和（0.61±0.07）μg/g。
结论 本研究建立的方法样品处理简单，方法特异性强，精确度高，重复性偏差小，回收率高，可用于当归芍药散提取物和含药血清中活性成分的质量控制。
关键词：高效液相色谱串联质谱法；阿魏酸；芍药苷；茯苓酸；当归芍药散；含药血清中图分类号：R284.1 文献标识码：A 文章编号：1005-5304(2021)01-0092-08DOI：10.19879/ki.1005-5304.202005099 开放科学（资源服务）标识码（OSID）：Content Determination of Three Active Components in Danggui Shaoyao Powder Extractsand Its Drug-containing Serum by HPLC-MS/MSSONG Zhenyan1, HE Pan2, LI Fuzhou1, HE Chunxiang1, YU Jingping1, CHENG Shaowu11. Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention andTreatment of Cardio-cerebral Diseases, Hunan University of Chinese Medicine, Changsha 410208, China;2. Research Institute of Zhongnan Grain and Oil Foods, Hunan Grain Group Co., Ltd, Changsha 410005, ChinaAbstract:Objective To establish a method for the determination of three active components in Danggui Shaoyao Powder extracts and its drug-containing serum by HPLC-MS/MS. Methods The extract samples were dissolved in methanol-water (1:1, V/V) solution, centrifuged and purified, and then passed through a 0.45 μm filter membrane. Serum samples were appropriately diluted, passed through the membrane and determined by HPLC-MS/MS. The column was Agilent Poroshell 120 EC-C18 (100 mm × 2.1 mm, 2.7 μm). The mobile phase of porcine acid was acetonitrile- 0.5 mmol/L ammonium acetate aqueous solution (9:1, V/V), and the mobile phase of ferulic acid and paeoniflorin was acetonitrile- 5 mmol/L ammonium acetate aqueous solution (gradient elution). The flow rate was 0.4 mL/min; the column temperature was 35 ℃; the injection volume was 5 μL. Electrospray ion source and negative ion mode were used; drying gas temperature was 350 ℃; drying gas flow rate was 12 L/min; detection method was multiple reaction monitoring. Results The linear relationship of ferulic acid, paeoniflorin and基金项目：国家自然科学基金（81774129、82004184）；湖南省自然科学基金面上项目（2018JJ2296）；湖南省自然科学基金青年基金（2019JJ50441）；湖南省高校创新平台开放基金项目（19K065）；湖南省教育厅科学研究项目（18B246）；湖南创新型省份建设专项（2019RS1064）通讯作者：成绍武，E-mail：****************.cnpachymic acid in Danggui Shaoyao Powder was good in the range of 0.1–20.0 μg/mL, 1–100 μg/mL, and 0.1– 20.0 μg/mL, respectively. The standard recovery was high and the repeatability was good. The contents of ferulic acid, paeoniflorin and pachymic acid in Danggui Shaoyao Powder extracts were (127.6±14.9)μg/g, (6081.8±468.0)μg/g, and (14.7±0.75)μg/g, respectively. The contents of ferulic acid and paeoniflorin in Danggui Shaoyao Powder- containing serum were (0.026±0.004) μg/g and (0.61±0.07) μg/g, respectively. Conclusion The method established in this study is simple in sample processing, strong in method specificity, high in accuracy, small in repeatability deviation, and high in recovery rate, and can be used for the quality control of the active components in the Danggui Shaoyao Powder extracts and drug-containing serum.Keywords: HPLC-MS/MS; ferulic acid; paeoniflorin; pachymic acid; Danggui Shaoyao Powder; drug-containing serum当归芍药散出自《金匮要略》，全方由当归、芍药、川芎、茯苓、白术和泽泻6味药组成，具有滋补肝肾、活血化瘀、化痰通络功效。
吕文良教授调治慢性萎缩性胃炎经验
-国医传承•吕文良教授调治慢性萎缩性胃炎经验曹正民1吕文良2武庆娟2【摘要】慢性萎缩性胃炎(chrouic aWophic gastritis,CAG)是临床常见的消化系统疾病，其病理表现为胃固有腺体破坏、数量减少，胃黏膜上皮和腺体萎缩等，其与胃癌的发生有一定的联系。
西医目前以对症治疗为主，但难以从根本上缓解症状，改善胃黏膜病变。
文章介绍了吕文良教授治疗慢性萎缩性胃炎的经验。
吕文良教授认为：慢性萎缩性胃炎的发病基础为脾胃虚弱;其发病的主要原因为饮食失节、情志不畅,其关键病机在于肝胃不和，湿热内蕴;因此，吕文亮教授在临床施治时，以疏肝和胃，清化湿热为治疗原则,善于运用对药调和肝、脾、胃三者关系，清化中焦湿热,可以有效缓解其症状，同时还具有不良反应少、可逆转病理变化等优点。
另附验案1则，以资佐证。
【关键词】吕文良;慢性萎缩性胃炎;对药;名医经验【中图分类号】貼73.3+2【文献标识码】AProfessor LYU WenliangS Experience in Treating Chronie Atrophie GastritisCAO Zheng-min1,LYU Wen-liang5,WU Qing-iung2(1.Beijing University of Chinese Medicine,Beijing140426；2.Department of Infectious Diseases,Guang'anmen Hospital,China Academy of Chinese Medicine Sciences,Beijing140253)[Abstrocti Chrouic aWophic easwi/s(CAG)is a commou clinical digestive system patholoeicai manifes-m/ous incluPe desWuctiou and decrease in the number of proper/aswic elands,aWophy of/aswic mucosal epitheliumand/ands.It is related to the occnrrence of/aswic cancer..Western medicine cnrrently focnses ou symptomatic treatment,but/is diVicue to fundamenm/y relieve symptoms and improve/aswic mucosal lesious.The article inWoduced in demil Professor Lu WenliangS expebence in treating chrouic aWophic/aswitis.Professor Lu Wenliang believes that the ousel ofchrouic atrophic/astri/s is the weabness of the spleen and stomach;md the main causes of its ousel arc eating disorUerand poor emohous.The kep pathopenesis is the discorbance of the liver and the stomach,which coutains dampness andheal.Therefore,Professor Lu Wenliang in clinical treatment,the principle of treatment is to soothe the liver and stomach,and to clear the damp-heat,and be/ood al using the medicine to recoucile the rem/ouship between the liver,spleen and stomach.To clear the damp-heal in the middle Jiao can effectively alleviate its symptoms with fewer adverse reactious,re-versidle patholopicai changes and other abvanmyes.One case is atmehed as evidence.【Keywords t LYU Wenliang；Chrouic AWophic Gastritis；Soothing Liver And Harmouizing Stomach;Medical Expc-enegie慢性萎缩性胃炎(chronic/mphie/ast/tis, CAG)是临床常见的消化系统疾病，其发病率随着年龄的增大而升高[],其病理表现为胃固有腺体破坏、数量减少，胃黏膜上皮和腺体萎缩等。
槐耳制剂辅助治疗肝细胞癌的作用机制及其临床应用进展
.槐耳制剂辅助治疗肝细胞癌的作用机制及其临床应用进展谢铠岭，徐 锋中国医科大学附属盛京医院普通外科，沈阳１１０００４摘要：肝细胞癌（ＨＣＣ）是我国第二大疾病相关死亡原因，严重威胁着居民健康。
近年研究证明中医药在ＨＣＣ综合治疗中发挥了重要作用。
槐耳制剂现已被推荐用于ＨＣＣ的治疗，其作用机制包括抑制血管生成、抑制ＨＣＣ细胞增殖、抑制侵袭与转移、诱导细胞凋亡、调节免疫功能等。
本文总结了槐耳抗ＨＣＣ机理研究和槐耳颗粒在临床中的应用进展，以期为后续研究和临床治疗提供参考。
关键词：癌，肝细胞；槐耳颗粒；治疗学基金项目：辽宁省自然科学基金（２０１８０５５１１９３，２０２０－ＭＳ－１８１）；盛京医院３４５人才工程计划（４０Ｂ）ＭｅｃｈａｎｉｓｍｏｆａｃｔｉｏｎｏｆＨｕａｉｅｒｇｒａｎｕｌｅｓｉｎｔｒｅａｔｍｅｎｔｏｆｈｅｐａｔｏｃｅｌｌｕｌａｒｃａｒｃｉｎｏｍａａｎｄａｄｖａｎｃｅｓｉｎｉｔｓｃｌｉｎｉｃａｌａｐｐｌｉｃａｔｉｏｎＸＩＥＫａｉｌｉｎｇ，ＸＵＦｅｎｇ．（ＤｅｐａｒｔｍｅｎｔｏｆＧｅｎｅｒａｌＳｕｒｇｅｒｙ，ＳｈｅｎｇｊｉｎｇＨｏｓｐｉｔａｌｏｆＣｈｉｎａＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ，Ｓｈｅｎｙａｎｇ１１０００４，Ｃｈｉｎａ）Ｃｏｒｒｅｓｐｏｎｄｉｎｇａｕｔｈｏｒ：ＸＵＦｅｎｇ，ｘｕｆｅｎｇｓｊｈ＠１２６．ｃｏｍ（ＯＲＣＩＤ：００００－０００１－９９８５－６５２７）Ａｂｓｔｒａｃｔ：Ｈｅｐａｔｏｃｅｌｌｕｌａｒｃａｒｃｉｎｏｍａ（ＨＣＣ）ｉｓｔｈｅｓｅｃｏｎｄｌｅａｄｉｎｇｃａｕｓｅｏｆｄｉｓｅａｓｅ－ｒｅｌａｔｅｄｄｅａｔｈｉｎＣｈｉｎａａｎｄｇｒｅａｔｌｙｔｈｒｅａｔｅｎｓｔｈｅｈｅａｌｔｈｏｆｒｅｓｉｄｅｎｔｓ．ＲｅｃｅｎｔｓｔｕｄｉｅｓｈａｖｅｓｈｏｗｎｔｈａｔｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎｅｐｌａｙｓａｎｉｍｐｏｒｔａｎｔｒｏｌｅｉｎｔｈｅｃｏｍｐｒｅｈｅｎｓｉｖｅｔｒｅａｔｍｅｎｔｏｆＨＣＣ．ＨｕａｉｅｒｇｒａｎｕｌｅｓｈａｖｅｂｅｅｎｒｅｃｏｍｍｅｎｄｅｄｆｏｒｔｈｅｔｒｅａｔｍｅｎｔｏｆＨＣＣ，ａｎｄｉｔｓｍｅｃｈａｎｉｓｍｏｆａｃｔｉｏｎｉｎｃｌｕｄｅｓｉｎｈｉｂｉｔｉｎｇａｎｇｉｏｇｅｎｅｓｉｓ，ｉｎｈｉｂｉｔｉｎｇｔｈｅｐｒｏｌｉｆｅｒａｔｉｏｎｏｆＨＣＣｃｅｌｌｓ，ｉｎｈｉｂｉｔｉｎｇｉｎｖａｓｉｏｎａｎｄｍｅｔａｓｔａｓｉｓ，ｉｎｄｕｃｉｎｇｃｅｌｌａｐｏｐｔｏｓｉｓ，ａｎｄｒｅｇｕｌａｔｉｎｇｉｍｍｕｎｅｆｕｎｃｔｉｏｎ．Ｔｈｉｓａｒｔｉｃｌｅｓｕｍ ｍａｒｉｚｅｓｔｈｅｒｅｓｅａｒｃｈａｄｖａｎｃｅｓｉｎｔｈｅａｎｔｉ－ＨＣＣｍｅｃｈａｎｉｓｍｏｆＨｕａｉｅｒｇｒａｎｕｌｅｓａｎｄｉｔｓａｐｐｌｉｃａｔｉｏｎｉｎｃｌｉｎｉｃａｌｐｒａｃｔｉｃｅ，ｉｎｏｒｄｅｒｔｏｐｒｏｖｉｄｅａｒｅｆｅｒｅｎｃｅｆｏｒｓｕｂｓｅｑｕｅｎｔｒｅｓｅａｒｃｈａｎｄｃｌｉｎｉｃａｌｔｒｅａｔｍｅｎｔ．Ｋｅｙｗｏｒｄｓ：Ｃａｒｃｉｎｏｍａ，Ｈｅｐａｔｏｃｅｌｌｕｌａｒ；ＨｕａｉｅｒＧｒａｎｕｌｅｓ；ＴｈｅｒａｐｅｕｔｉｃｓＲｅｓｅａｒｃｈｆｕｎｄｉｎｇ：ＮａｔｕｒａｌＳｃｉｅｎｃｅＦｏｕｎｄａｔｉｏｎｏｆＬｉａｏｎｉｎｇＰｒｏｖｉｎｃｅ（２０１８０５５１１９３，２０２０－ＭＳ－１８１）；３４５ＴａｌｅｎｔＰｒｏｊｅｃｔｏｆＳｈｅｎｇｊｉｎｇＨｏｓｐｉｔａｌ（４０Ｂ）ＤＯＩ：１０．３９６９／ｊ．ｉｓｓｎ．１００１－５２５６．２０２２．０３．０３８收稿日期：２０２１－０７－３０；录用日期：２０２１－１０－０８通信作者：徐锋，ｘｕｆｅｎｇｓｊｈ＠１２６．ｃｏｍ 原发性肝癌是我国第二大疾病相关死亡原因，其中８０％以上为肝细胞癌（ＨＣＣ），严重威胁着居民的生命和健康［１］。
论中成药治疗原发性骨质疏松症临床应用-白津硕
97第19卷 第8期 2017 年 8 月辽宁中医药大学学报JOURNAL OF LIAONING UNIVERSITY OF TCMVol. 19 No. 8 Aug .，2017骨质疏松症（Osteoporosis）是于1885年由Pommer 首先提出。
随着现代生理学和病理学的不断发展以及对骨质疏松症的逐步认识，现普遍认为骨质疏松症是以骨量减少、骨的微观结构退化为基本特征，致使骨的脆性增加、易于发生骨折的一种全身性骨骼疾病[1]。
随着人类社会的发展，就中国而言，我国2010年第6次全国人口普查结果表明，我国现有60岁以上人口占全国人口总数的13.26%，而65岁以上的人口占总人数的8.87%。
标志着我国现已成为人口老龄化国家[2]。
同时骨质疏松症也已经成为全球所共同关注的健康问题。
目前依据西医学对骨质疏松症的病因学认识，用药大致分为骨形成促进剂，其代表药物甲状腺激素；以及骨吸收抑制剂，其代表药物为双膦酸盐类药物、雌激素和选择性雌激素受体调节剂[3]。
依据现在较为公认的《中医虚证参考标准》[4]以及《中西结合诊治骨质疏松症》[5]对于骨质疏松症在中医分型的认识，暂认为骨质疏松症的发生多基于肾阳虚、肝肾阴虚、脾肾阳虚以及气血瘀滞为主，本文将依据中医独有的辨证分析理论以上述4种证型为分类原则，对现有临床应用的中成药加以分析略述，望对临床指导用药稍有增益。
下文中将对药物的药效成分加以分析，因此类药物成分中有相同的药物，故在论述时将不逐一赘加分析。
1肾阳虚型肾阳虚患者临床多表现为：腰背冷痛，酸软乏力，甚则驼背弯腰，活动受限，畏寒喜暖、遇冷加重、尤以下肢为甚，小便频多，舌淡，苔白，脉沉细或沉弦。
依据文献查阅对比发现，仙灵骨葆胶囊对于此证型应用较广，仙灵骨葆胶囊是国家已经批准上市治疗骨质疏松的苗药制剂，其组成成分主要有淫羊藿、知母、续断、丹参、补骨脂、地黄等6味中草药。
论中成药治疗原发性骨质疏松症临床应用白津硕1，关雪峰2（1.辽宁中医药大学，辽宁 沈阳 110847；2.辽宁中医药大学附属医院，辽宁 沈阳 110032）摘 要：随着全球老龄化社会的到来，原发性骨质疏松症的治疗问题越发被全球瞩目。
张鸣鹤教授治疗类风湿性关节炎临证经验概要
中华全科医学2〇2〇年丨〇月第丨8卷第丨〇期C h i n e s e Journal of G e n e r a丨Practice, O c t o b e r 2〇2〇,V o丨.丨8，No. 10•1735••预防/保健中医/康复•张鸣鹤教授治疗类风湿性关节炎临证经验概要起杨寒1，徐云生21.山东中医药大学研究生院，山东济南250014;2.山东中医药大学第二附属医院内分泌科，山东济南250001摘要：目的类风湿性关节炎的治疗仍为临床一大难题。
本文总结张鸣鹤教授治疗类风湿性关节炎临床经验。
方法2019年9月一2020年3月跟随张鸣鹤教授临证侍诊,收集相关医案，并整理张鸣鹤教授处方及诊间评语，附以临床诊治完整病案1例。
查阅相关文献，采取定性研究的方法，总结不同证型患者的处方特点，挖掘张鸣鹤教授类风湿性关节炎辨证论治及特色疗法的临证经验。
结果张鸣鹤教授对类风湿性关节炎的临床经验有热痹为多、辨证治疗、药物运用以及关节变形防治等4个方面，其中辨证临床以热痹为多，前期应注重风湿热邪的轻重比较,佐以活血化瘀、滋阴清热，后期以扶正为主，补益肝肾、清解余毒。
张鸣鹤教授在药物运用中注重其归经和特殊作用，对类风湿性关节炎临床药物选用有其?i到的见解。
植物类药物运用较为频繁，强调不同的药物可用于相对应的症状及发病部位。
虫类药物使用较少，但在通络治疗上有点睛作用。
同时提出，类风湿性关节炎应防治结合，规范用药;对关节变形但骨质尚未融合的患者提出牵拉矫形的治疗方法，显著提升患者的生存质量。
结论运用中医理论体系宏观分析类风湿性关节炎中医治疗经验，热痹理论以及用药规律在临床辨证治疗过程中取得显著疗效，对比其他名中医治疗经验，体现出中医“天人合一、三因制宜”的思想，以期在中医治疗类风湿性关节炎时有所借鉴。
关键词:热痹;清热解毒;药物;关节变形;类风湿性关节炎中图分类号：R593.22 R242文献标识码：A文章编号：16744152(2020)10-1735^04D01：10. 16766/j. cnki. issn. 1674 - 4152.001606Summary of professor Zhang Minghe^ clinical experience in the treatment of rheumatoid arthritisZHAO Yang-han* , XU Yun-sheng*Graduate School of Shandong Traditional Chinese Medicine University, Jinan, Shandong250014, China Abstract ：Objective To summarize professor Zhang Minghes clinical experience in the treatment of rheumatoid arthritis. Methods Followed professor Zhang Minghes clinical consultation, collected relevant medical rases, and sorted outprofessor Zhang Minghe^ prescriptions and comments, with 1case of complete clinical diagnosis and treatment. By referring to relevant literature and adopting qualitative research method, the prescription characteristics of patients with different syndrome types were summarized, and the clinical experience of professor Zhang Minghes dialectical treatment andcharacteristic therapy of rheumatoid arthritis was explored. Results Professor Zhang Minghe s clinical experience inrheumatoid arthritis includes four aspects：clinical dialectical treatment, drug application, and prevention and treatmentof joint deformation. Dialectical clinical pyretic arthralgia for the most part, early should pay attention to the weight ofrheumatic heat evil comparison, assisted by huoxue to remove blood stasis, nourishing Yin clearing heat, later to supportthe main, nourishing the liver and kidney, clearing the residual poison. Professor Zhang Minghe pay attention to its regression and special function in the application of drugs, and had his unique views on the selection of clinical drugs forrheumatoid arthritis. The use of plant drugs was frequent, emphasizing that different drugs can be used for the corresponding symptoms and the location of disease. Insect drugs were seldom used, but they have a punchline effect in thetreatment of collaterals. At the same time, rheumatoid arthritis should be combined with prevention and treatment, standardized drug use. For patients with deformities of joints but not yet bone fusion, a method of traction orthopetlic treatmentwas proposed, which significantly improved the quality of life of the patients. Conclusion On the basis of the theory oftraditional Chinese medicine system macro analysis rheumatoid arthritis treatment experience of TCM. Compared with other Chinese medicine treatment experience, pyretic arthralgia theory and drug laws in the process of clinical dialecticaltreatment have made significant efficacy, reflect the traditional Chinese medicine " nature and humanity, three due to thefollowing" thinking, in order to the reference when the doctor of traditional Chinese medicine treatment of rheumatoid arthritis.Key w ords：Pyretic arthralgia；Clearing heat and detoxification；Drugs；Joint deformation；Rheumatoid arthritis张鸣鹤教授作为全国名老中医专家，对治疗风湿 免疫性疾病有着丰富的临床经验。
中医给我看病作文英语
中医给我看病作文英语Traditional Chinese Medicine (TCM) has been an integral part of healthcare in China for thousands of years, and it continues to gain recognition worldwide for its holistic approach to healing. Recently, I had the opportunity to experience TCM firsthand when seeking treatment for a health issue. In this essay, I will share my experience of consulting with a TCM practitioner and the insights gained from this traditional form of medicine.Upon entering the TCM clinic, I was struck by the serene ambiance and the welcoming demeanor of the staff. The waiting area was adorned with soothing Chinese artwork and the faint scent of herbal medicine lingered in the air, creating a tranquil atmosphere. After a brief wait, I was ushered into a consultation room where I met the TCM practitioner, a knowledgeable and experienced individual who exuded a sense of calm and confidence.During the initial consultation, the practitioner askeddetailed questions about my medical history, current symptoms, lifestyle, diet, and emotional well-being. This thorough inquiry was unlike any other medical consultation I had experienced before. The practitioner explained thatin TCM, every individual is seen as unique, and the focusis not just on treating symptoms but on restoring balance to the body as a whole.After gathering information, the practitioner proceeded with a physical examination, which included palpation of my pulse and inspection of my tongue. In TCM, the pulse is believed to reflect the state of various organs and meridians in the body, while the tongue's appearance can provide insights into internal imbalances. This diagnostic approach fascinated me, as it seemed to offer a deeper understanding of my health beyond what modern medical tests could reveal.Based on the findings from the consultation and examination, the practitioner formulated a personalized treatment plan. This plan encompassed a combination of acupuncture, herbal medicine, dietary recommendations, andlifestyle adjustments. I was initially skeptical about acupuncture, having never tried it before, but the practitioner's gentle explanation of its benefits and the scientific evidence supporting its efficacy eased my apprehensions.The acupuncture session itself was a surprisingly relaxing experience. The insertion of thin needles at specific points on my body was virtually painless, and Ifelt a deep sense of calm and well-being during the treatment. The practitioner explained that acupunctureworks by stimulating the body's natural healing mechanisms and restoring the flow of Qi, or vital energy, along the body's meridians.In addition to acupuncture, I was prescribed a customized herbal medicine formula tailored to address my specific health concerns. The practitioner explained the properties of each herb and how they would work synergistically to promote healing and rebalance my body. I appreciated the emphasis on natural remedies and the avoidance of unnecessary medications or invasive procedures.Alongside the acupuncture and herbal treatment, the practitioner offered valuable lifestyle advice, including stress-reduction techniques, dietary modifications, and gentle exercises such as Qi Gong or Tai Chi. These holistic recommendations highlighted the interconnectedness of physical, emotional, and spiritual well-being in TCM philosophy.Over the course of several weeks, I diligently followed the TCM treatment plan. Gradually, I noticed improvementsin my symptoms, increased energy levels, and a greater sense of overall vitality. What struck me most was not just the alleviation of my physical complaints but the profound sense of balance and harmony that TCM had brought to my life.Reflecting on my experience with TCM, I gained a newfound appreciation for the depth and wisdom oftraditional healing practices. The personalized approach, emphasis on natural remedies, and focus on restoring balance resonated with me on a profound level. While modernmedicine certainly has its merits, I believe that integrating elements of TCM into healthcare can offer holistic benefits that complement conventional treatments.In conclusion, my journey with TCM was enlightening and transformative. It opened my eyes to a different perspective on health and healing, one that values the interconnectedness of mind, body, and spirit. I am grateful for the opportunity to have experienced the wisdom of TCM and would encourage others to explore its potential intheir own wellness journeys.。
中国传统医术的英语作文
中国传统医术的英语作文Chinese traditional medicine, you know, it's like this ancient treasure trove of health wisdom passed down from, like, centuries ago. Picture this: herbs, acupuncture, cupping, all that jazz. It's not your typical pop-a-pill-and-you're-good kinda deal. Nah, it's more like this holistic vibe, where they're all about balancing your yin and yang, whatever that means.So, imagine you're feeling all out of whack, maybe your chi's not flowing right or something. Instead of hitting up your local pharmacy for some over-the-counter meds, you might wander into a traditional Chinese medicine (TCM) clinic. And let me tell you, it's a whole different worldin there. You got these doctors in long robes, examining your tongue like it's some crystal ball or something,trying to decode the mysteries of your body.And then there's acupuncture. Yeah, those tiny needles that they stick all over your body. Sounds kinda scary,right? But people swear by it. They say it's like tapping into your body's natural energy flow, releasing all those blockages and stuff. I mean, I've never tried it myself, but hey, to each their own, right?Oh, and don't even get me started on cupping. You've probably seen those crazy photos of people with these big red circles all over their backs. It's like they got attacked by a giant octopus or something. But apparently,it's supposed to, like, suck out all the toxins from your body and improve your circulation. Sounds intense, but hey, if it works...And let's not forget about the herbs. TCM is all about using nature's pharmacy to heal what ails you. Ginseng, ginger, goji berries – you name it, they got it. It's like a whole other grocery list of remedies, except instead of eating them, you're brewing them into some funky-tasting tea.But here's the thing about Chinese traditional medicine – it's not just about treating the symptoms, it's aboutgetting to the root cause of your health issues. It's about finding harmony within yourself and with the world around you. And whether you buy into all that yin-yang stuff or not, you gotta admit, there's something kinda beautiful about that approach to healing.。
中医治疗新冠的英语作文
中医治疗新冠的英语作文In the face of the global pandemic caused by COVID-19, Traditional Chinese Medicine (TCM) has emerged as a valuable resource in the fight against the virus. TCM, with its rich history and holistic approach to healthcare,offers a unique perspective in the treatment of COVID-19, complementing and, in some cases, enhancing Western medical practices.The cornerstone of TCM is the belief that health and disease are manifestations of the harmony or imbalance between the body's qi (vital energy) and its surrounding environment. COVID-19, according to TCM theory, is often viewed as a result of an external pathogenic factor invading the body and disrupting its internal balance. Therefore, TCM treatment focuses on strengthening thebody's immune system, clearing pathogenic factors, and restoring the overall harmony of qi.Herbal medicine, a key component of TCM, plays a significant role in COVID-19 treatment. Herbal formulas, often tailored to the individual patient's symptoms and constitution, aim to alleviate symptoms such as fever,cough, and fatigue. These formulas may include herbs that have antiviral, immunomodulatory, and anti-inflammatory properties, which can help the body fight the virus and reduce the severity of the disease.In addition to herbal medicine, TCM practitioners also utilize acupuncture and other non-pharmacological techniques in the treatment of COVID-19. Acupuncture, by stimulating specific points on the body, is believed to regulate qi flow, enhance immune function, and relieve symptoms associated with the virus. These techniques, combined with lifestyle recommendations such as dietary modifications and exercise, aim to create a comprehensive approach to healing.The integration of TCM into COVID-19 treatment has been met with varying degrees of acceptance and skepticism. While some studies have shown promising results in terms of symptom relief and recovery time, the scientific evidence supporting TCM's effectiveness in treating COVID-19 isstill evolving. However, the holistic and individualized approach of TCM offers a valuable complement to Western medicine, particularly in cases where patients may notrespond well to conventional treatments or where symptoms are mild.It's worth noting that TCM should not be viewed as a standalone treatment for COVID-19 but rather as a complementary approach that can be integrated into a comprehensive healthcare plan. TCM practitioners often work closely with Western doctors to provide integrated carethat takes into account both the biological and psychological aspects of the disease.In conclusion, Traditional Chinese Medicine offers a unique and valuable perspective in the treatment of COVID-19. By focusing on strengthening the body's immune system and restoring internal balance, TCM can help alleviate symptoms, improve recovery time, and enhance the overall quality of life for patients with the virus. While the scientific evidence supporting its efficacy is still developing, the holistic and individualized approach of TCM remains a promising avenue in the fight against COVID-19. **中医治疗新冠的作用**面对由新冠病毒引起的全球大流行病，中医（TCM）已成为抗击病毒的重要资源。
中医在疫情中的作用英语作文
中医在疫情中的作用英语作文The Role of Traditional Chinese Medicine in the PandemicTraditional Chinese medicine (TCM) has played asignificant role in the fight against the COVID-19 pandemic. As a holistic approach to healthcare, TCM has offered a complementary perspective to the Western medical model, providing valuable insights and treatments that have contributed to the overall management of the crisis.One of the key contributions of TCM in the pandemic has been its emphasis on preventive measures. TCM practitioners have long advocated for maintaining a balanced and harmonious state of the body, known as "Qi," to enhance the body's natural ability to resist disease. During the pandemic, TCM has provided guidance on lifestyle adjustments, such as dietary recommendations and herbal remedies, to strengthen the immune system and promoteoverall well-being.Moreover, TCM has been actively involved in thetreatment of COVID-19 patients. In China, TCM has been integrated into the national COVID-19 treatment protocols,with TCM therapies being used in conjunction with Western medical interventions. This integrated approach has shown promising results, with some studies suggesting that TCM-based treatments can alleviate symptoms, reduce theseverity of the disease, and potentially shorten the recovery time for COVID-19 patients.One of the notable TCM-based treatments is the use of herbal formulas. These formulas, developed based on the principles of TCM, have been studied for their potential to address the specific symptoms and pathological patterns associated with COVID-19. For instance, the "Lianhua Qingwen" formula, which contains a combination of herbs such as honeysuckle, forsythia, and ephedra, has been widely used in China and has shown positive results in clinical trials.Furthermore, TCM has also contributed to the understanding of the underlying mechanisms of COVID-19. By analyzing the disease patterns and symptoms from a TCM perspective, researchers have identified potential therapeutic targets and developed innovative TCM-based strategies for disease management. This holistic approachhas the potential to provide a more comprehensive understanding of the complex interplay between the virus, the human body, and the environment.In addition to its clinical applications, TCM has also played a role in the psychological and emotional well-being of individuals during the pandemic. TCM emphasizes the importance of maintaining a balanced state of mind and emotions, which can be particularly relevant in times of stress and uncertainty. TCM-based practices, such as acupuncture, tai chi, and meditation, have been utilized to help individuals cope with the mental and emotional challenges brought about by the pandemic.However, it is important to note that the integration of TCM and Western medicine in the pandemic response has not been without its challenges. Differences in epistemological frameworks, research methodologies, and regulatory systems have sometimes led to tensions and misunderstandings. Nonetheless, efforts are being made to bridge these gaps and foster greater collaboration and mutual understanding between the two medical systems.In conclusion, the role of traditional Chinese medicine in the COVID-19 pandemic has been multifaceted and significant. From preventive measures to complementary treatments, TCM has offered a unique perspective and valuable contributions to the overall management of the crisis. As the world continues to navigate the challenges posed by the pandemic, the integration of TCM and Western medicine holds the promise of a more comprehensive and effective approach to healthcare.中医在疫情中的作用中医在应对新冠疫情中发挥了重要作用。
英语应用文 中医讲座
英语应用文中医讲座Chinese Medicine Lecture.What is Chinese medicine?Chinese medicine is a traditional system of medicine that has been practiced in China for thousands of years. It is based on the belief that the human body is a microcosm of the universe, and that all things in nature are interconnected. Chinese medicine uses a variety of techniques to treat illness, including acupuncture, herbal medicine, moxibustion, and massage.What are the benefits of Chinese medicine?Chinese medicine has been shown to be effective in treating a wide range of conditions, including pain, allergies, digestive problems, and mental health issues. It can also help to improve overall health and well-being.How does Chinese medicine work?Chinese medicine works by restoring balance to the body. When the body is in balance, it is able to heal itself. Chinese medicine uses a variety of techniques to restore balance, including acupuncture, herbal medicine, moxibustion, and massage.Acupuncture.Acupuncture is a technique that involves inserting thin needles into the skin at specific points on the body. These points are located along meridians, which are channels of energy that run throughout the body. Acupuncture can helpto relieve pain, improve circulation, and promote healing.Herbal medicine.Herbal medicine is a technique that involves usingplants to treat illness. Chinese herbal medicine uses a variety of plants, each with its own unique properties. Herbal medicine can help to improve digestion, boost theimmune system, and relieve pain.Moxibustion.Moxibustion is a technique that involves burning a herb called mugwort on the skin. Moxibustion can help to warmthe body, relieve pain, and promote healing.Massage.Massage is a technique that involves manipulating the body's soft tissues. Massage can help to relieve pain, improve circulation, and promote relaxation.Is Chinese medicine safe?Chinese medicine is generally safe when it is practiced by a qualified practitioner. However, there are some potential risks associated with Chinese medicine, including:Allergic reactions to herbs.Skin irritation from acupuncture.Bruising from moxibustion.It is important to talk to your doctor before starting any Chinese medicine treatment.中文回答：什么是中医？中医是我国传统意义上的医学，在其发展历程中至今已历经上千年的时间。
传统的中国疗法英语作文
传统的中国疗法英语作文Traditional Chinese Therapy。
Traditional Chinese therapy, also known as TCM, has a history of thousands of years and is considered one of the most effective and comprehensive systems of health care in the world. It encompasses a range of traditional practices and treatments, including acupuncture, herbal medicine, massage (tui na), cupping, and qigong. These therapies are based on the principles of yin and yang, the five elements, and the flow of qi, or vital energy, through the body.Acupuncture is perhaps the most well-known and widely practiced form of TCM. It involves the insertion of thin needles into specific points on the body to stimulate the flow of qi and restore balance to the body's energy. This can help to alleviate pain, improve circulation, and promote overall well-being. Many people find acupuncture to be a safe and effective treatment for a wide range of conditions, including chronic pain, migraines, and anxiety.Herbal medicine is another cornerstone of TCM. Practitioners use a wide variety of plants, minerals, and animal products to create customized herbal formulas that are tailored to each individual's specific needs. These formulas can be taken in the form of teas, powders, or pills, and are used to address a wide range of health concerns, from digestive issues to respiratory problems to hormonal imbalances.In addition to acupuncture and herbal medicine, TCM also includes a number of other therapeutic modalities. Tui na, or Chinese massage, is a form of bodywork that involves the manipulation of the body's soft tissues to promote healing and relaxation. Cupping is a technique in which heated glass cups are applied to the skin to create a vacuum, which can help to alleviate muscle tension and improve circulation. Qigong, a form of gentle exercise and meditation, is also an important part of TCM, as it is believed to help balance the flow of qi and promote overall health and vitality.One of the key principles of TCM is the idea oftreating the whole person, rather than just the symptoms of a particular condition. This means that TCM practitioners take into account not only a person's physical symptoms, but also their emotional, mental, and spiritual well-being. By addressing the underlying causes of illness and promoting overall balance and harmony within the body, TCM can help to prevent disease and promote long-term health and wellness.In recent years, TCM has gained popularity and recognition in the West, as more and more people seek out alternative and holistic approaches to health care. Many Western medical practitioners are now incorporating TCMinto their practices, and TCM clinics and wellness centers can be found in cities and towns across the globe. This growing interest in TCM is a testament to its effectiveness and the growing body of scientific research supporting its use.In conclusion, traditional Chinese therapy is a rich and complex system of health care that offers a holisticapproach to healing and wellness. With its emphasis on restoring balance and harmony within the body, TCM has the potential to help people live healthier, happier lives. Whether it's through acupuncture, herbal medicine, massage, or qigong, TCM offers a wealth of tools and techniques for promoting health and well-being in the modern world.。
慢加急性肝衰竭中西医结合诊疗指南
!()*+,!ＤＯＩ：１０．３９６９／ｊ．ｉｓｓｎ．１００１－５２５６．２０２３．０７．００６慢加急性肝衰竭中西医结合诊疗指南中国中西医结合学会，中华中医药学会，中华医学会通信作者：王宪波，ｗａｎｇｘｉａｎｂｏ６３８＠１６３．ｃｏｍ（ＯＲＣＩＤ：００００－０００２－３５９３－５７４１）摘要：慢加急性肝衰竭（ＡＣＬＦ）是在慢性肝病基础上，由各种诱因引起的以黄疸急性加深、凝血功能障碍等肝衰竭表现的临床症候群，短期内出现多脏器功能衰竭及高病死率是其主要特征。
慢加急性肝衰竭中医学属于“急黄”“瘟黄”“肝瘟”等范畴，目前临床上尚缺乏特效的内科治疗手段。
本指南以解决“中西医临床关键问题”为导向，工作组参考ＰＩＣＯ（Ｐａｒｔｉｃｉｐａｎｔｓ、Ｉｎｔｅｒｖｅｎｔｉｏｎｓ、Ｃｏｍｐａｒｉｓｏｎｓ、Ｏｕｔｃｏｍｅｓ）原则构建ＡＣＬＦ相关临床问题，遵循循证医学原则，在对近１０年ＡＣＬＦ中西医结合疗效临床证据进行系统梳理和客观评价的基础上，参考最新发表的国际、国内相关诊疗指南、专家共识等，并广泛征求多学科专家的意见，最终形成本指南，旨在为临床医师诊断和治疗ＡＣＬＦ提供指导和参考意见，进一步提高我国ＡＣＬＦ诊治水平。
关键词：慢加急性肝功能衰竭；中西医结合疗法；诊疗准则ＧｕｉｄｅｌｉｎｅｓｆｏｒｔｈｅｉｎｔｅｇｒａｔｅｄｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅａｎｄＷｅｓｔｅｒｎｍｅｄｉｃｉｎｅｄｉａｇｎｏｓｉｓａｎｄｔｒｅａｔｍｅｎｔｏｆａｃｕｔｅ－ｏｎ－ｃｈｒｏｎｉｃｌｉｖｅｒｆａｉｌｕｒｅＣｈｉｎｅｓｅＡｓｓｏｃｉａｔｉｏｎｏｆＩｎｔｅｇｒａｔｉｖｅＭｅｄｉｃｉｎｅ，ＣｈｉｎａＡｓｓｏｃｉａｔｉｏｎｏｆＣｈｉｎｅｓｅＭｅｄｉｃｉｎｅ，ＣｈｉｎｅｓｅＭｅｄｉｃａｌＡｓｓｏｃｉａｔｉｏｎＣｏｒｒｅｓｐｏｎｄｉｎｇａｕｔｈｏｒ：ＷＡＮＧＸｉａｎｂｏ，ｗａｎｇｘｉａｎｂｏ６３８＠１６３．ｃｏｍ（ＯＲＣＩＤ：００００－０００２－３５９３－５７４１）Ａｂｓｔｒａｃｔ：Ａｃｕｔｅ－ｏｎ－ｃｈｒｏｎｉｃｌｉｖｅｒｆａｉｌｕｒｅ（ＡＣＬＦ）ｉｓａｃｌｉｎｉｃａｌｓｙｎｄｒｏｍｅｗｉｔｈｔｈｅｍａｎｉｆｅｓｔａｔｉｏｎｓｏｆｌｉｖｅｒｆａｉｌｕｒｅｓｕｃｈａｓａｃｕｔｅｄｅｅｐｅｎｉｎｇｏｆｊａｕｎｄｉｃｅａｎｄｃｏａｇｕｌａｔｉｏｎｄｉｓｏｒｄｅｒｄｕｅｔｏｖａｒｉｏｕｓｐｒｅｄｉｓｐｏｓｉｎｇｆａｃｔｏｒｓ，ｃｈａｒａｃｔｅｒｉｚｅｄｂｙｍｕｌｔｉｐｌｅｏｒｇａｎｆａｉｌｕｒｅａｎｄｈｉｇｈｍｏｒｔａｌｉｔｙｒａｔｅｗｉｔｈｉｎａｓｈｏｒｔｐｅｒｉｏｄｏｆｔｉｍｅ．ＩｎｔｅｒｍｓｏｆｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎｅ，ＡＣＬＦｂｅｌｏｎｇｓｔｏｔｈｅｃａｔｅｇｏｒｉｅｓｏｆ“ａｃｕｔｅｊａｕｎｄｉｃｅ”，“ｓｃｏｕｒｇｅｊａｕｎｄｉｃｅ”，ａｎｄ“ｌｉｖｅｒｆａｉｌｕｒｅ”，ａｎｄｎｏｗｔｈｅｒｅｉｓｓｔｉｌｌａｌａｃｋｏｆｓｐｅｃｉｆｉｃｍｅｄｉｃａｌｔｒｅａｔｍｅｎｔｍｅｔｈ ｏｄｓｉｎｃｌｉｎｉｃａｌｐｒａｃｔｉｃｅ．Ｗｉｔｈｔｈｅｏｒｉｅｎｔａｔｉｏｎｏｆ“ｋｅｙｃｌｉｎｉｃａｌｐｒｏｂｌｅｍｓｏｆｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅａｎｄＷｅｓｔｅｒｎｍｅｄｉｃｉｎｅ”ｉｎｔｈｅｇｕｉｄｅｌｉｎｅｓ，ｔｈｅｗｏｒｋｉｎｇｇｒｏｕｐｃｏｎｓｔｒｕｃｔｅｄｔｈｅｃｌｉｎｉｃａｌｐｒｏｂｌｅｍｓａｓｓｏｃｉａｔｅｄｗｉｔｈＡＣＬＦｂａｓｅｄｏｎｔｈｅｐｒｉｎｃｉｐｌｅｓｏｆＰａｒｔｉｃｉｐａｎｔｓ，Ｉｎｔｅｒｖｅｎｔｉｏｎｓ，Ｃｏｍｐａｒｉｓｏｎｓ，ａｎｄＯｕｔｃｏｍｅｓａｎｄｆｏｌｌｏｗｅｄｔｈｅｐｒｉｎｃｉｐｌｅｓｏｆｅｖｉｄｅｎｃｅ－ｂａｓｅｄｍｅｄｉｃｉｎｅ．Ｔｈｒｏｕｇｈｓｙｓｔｅｍａｔｉｃｒｅ ｖｉｅｗａｎｄｏｂｊｅｃｔｉｖｅｅｖａｌｕａｔｉｏｎｏｆｔｈｅｃｌｉｎｉｃａｌｅｖｉｄｅｎｃｅｃｏｎｃｅｒｎｉｎｇｔｈｅｅｆｆｉｃａｃｙｏｆｉｎｔｅｇｒａｔｅｄｔｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅａｎｄＷｅｓｔｅｒｎｍｅｄｉｃｉｎｅｔｈｅｒａｐｙｆｏｒＡＣＬＦｉｎｔｈｅｐａｓｔ１０ｙｅａｒｓ，ｔｈｅｇｕｉｄｅｌｉｎｅｓｗｅｒｅｄｅｖｅｌｏｐｅｄｗｉｔｈｒｅｆｅｒｅｎｃｅｔｏｔｈｅｌａｔｅｓｔｄｉａｇｎｏｓｉｓａｎｄｔｒｅａｔ ｍｅｎｔｇｕｉｄｅｌｉｎｅｓａｎｄｅｘｐｅｒｔｃｏｎｓｅｎｓｕｓｉｎＣｈｉｎａａｎｄｇｌｏｂａｌｌｙａｎｄｔｈｅｃｏｍｍｅｎｔｓｆｒｏｍｍｕｌｔｉｄｉｓｃｉｐｌｉｎａｒｙｅｘｐｅｒｔｓ，ｉｎｏｒｄｅｒｔｏｐｒｏ ｖｉｄｅｇｕｉｄａｎｃｅａｎｄｒｅｆｅｒｅｎｃｅｆｏｒｔｈｅｄｉａｇｎｏｓｉｓａｎｄｔｒｅａｔｍｅｎｔｏｆＡＣＬＦａｍｏｎｇｃｌｉｎｉｃｉａｎｓａｎｄｆｕｒｔｈｅｒｉｍｐｒｏｖｅｔｈｅｄｉａｇｎｏｓｉｓａｎｄｔｒｅａｔｍｅｎｔｌｅｖｅｌｏｆＡＣＬＦｉｎＣｈｉｎａ．Ｋｅｙｗｏｒｄｓ：Ａｃｕｔｅ－Ｏｎ－ＣｈｒｏｎｉｃＬｉｖｅｒＦａｉｌｕｒｅ；ＩｎｔｅｇｒａｔｅｄＣｈｉｎｅｓｅＴｒａｄｉｔｉｏｎａｌａｎｄＷｅｓｔｅｒｎＭｅｄｉｃｉｎｅＴｈｅｒａｐｙ；ＰｒａｃｔｉｃｅＧｕｉｄｅｌｉｎｅ１ 范围本指南适用于慢加急性肝衰竭（ａｃｕｔｅ－ｏｎ－ｃｈｒｏｎｉｃｌｉｖｅｒｆａｉｌｕｒｅ，ＡＣＬＦ）的诊断、辨证、治疗、预防与调护等，供各级医疗机构的肝病科、传染科、消化科、急诊科、中医消化科、中医感染病科等相关科室医护人员的使用。
中医治疗理念英语作文
中医治疗理念英语作文Title: Traditional Chinese Medicine Treatment Philosophy。
Traditional Chinese Medicine (TCM) has a rich history and a unique treatment philosophy that has been practicedfor thousands of years. This holistic approach tohealthcare emphasizes the balance between the mind, body, and spirit, viewing the body as a complex system of interconnected parts. TCM treatment principles are based on ancient Chinese philosophical concepts such as Yin and Yang, Qi (vital energy), and the Five Elements. In this essay, we will explore the fundamental principles of TCM treatment philosophy and how they guide practitioners in diagnosing and treating illnesses.Central to TCM treatment philosophy is the concept of Yin and Yang, representing the dualistic nature of the universe. Yin and Yang are opposite forces that complement each other and are present in all aspects of life,including the human body. Health is believed to be achieved when Yin and Yang are in harmony, while illness occurs when there is an imbalance between these two forces. TCM practitioners aim to restore balance by identifying the underlying cause of the imbalance and prescribing treatments to harmonize Yin and Yang.Another key concept in TCM is Qi, often described as vital energy or life force. Qi flows through the body along meridians, or energy pathways, and is essential for maintaining health and vitality. According to TCM theory, blockages or disruptions in the flow of Qi can lead to illness and discomfort. TCM treatments such as acupuncture, herbal medicine, and Qi Gong are designed to restore the smooth flow of Qi and promote healing.The Five Elements theory is another fundamental aspect of TCM treatment philosophy. This theory categorizes the various phenomena in nature and the human body into five elements: Wood, Fire, Earth, Metal, and Water. Each element is associated with specific organs, seasons, emotions, and qualities. TCM practitioners use the Five Elements theoryto understand the interconnectedness of different organ systems and diagnose imbalances that may manifest as physical or emotional symptoms. For example, a person with symptoms of anger and irritability may be diagnosed with Liver Qi stagnation, according to the Five Elements theory.In addition to these core principles, TCM treatment philosophy also emphasizes the importance of individualized care and prevention. TCM practitioners take into account the unique constitution and lifestyle of each patient when designing treatment plans. Rather than simply treating symptoms, TCM focuses on addressing the root cause of illness and restoring the body's innate ability to heal itself. Through dietary therapy, lifestyle modifications, and mind-body practices, patients are empowered to take an active role in their own health and well-being.One of the strengths of TCM treatment philosophy is its versatility and adaptability. While rooted in ancient wisdom, TCM continues to evolve and integrate modern scientific knowledge and techniques. In recent years, there has been growing interest in evidence-based research tovalidate the efficacy of TCM treatments and understandtheir mechanisms of action. This integration of traditional wisdom with contemporary science holds promise for the future of healthcare, offering a holistic approach that addresses the physical, emotional, and spiritual dimensions of health.In conclusion, Traditional Chinese Medicine treatment philosophy is based on ancient wisdom and holistic principles that emphasize the interconnectedness of mind, body, and spirit. By restoring balance to the body'snatural systems and addressing the root cause of illness, TCM offers a comprehensive approach to healthcare that promotes healing and well-being. As interest in holistic medicine continues to grow, TCM stands as a timeless tradition that offers valuable insights into the nature of health and the art of healing.This essay draws upon the fundamental principles of Traditional Chinese Medicine treatment philosophy, exploring concepts such as Yin and Yang, Qi, the Five Elements, and individualized care. Through a holisticapproach that addresses the interconnectedness of mind, body, and spirit, TCM offers a comprehensive framework for understanding health and treating illness. As interest in holistic medicine continues to grow, TCM stands as a timeless tradition that offers valuable insights into the art of healing and the nature of well-being.。
中国中医英文介绍
中国中医英文介绍中国中医英文介绍Traditional Chinese Medicine ("TCM") is an integral part of Chinese culture. Ithas made great contributions to the prosperity of China. Today both of TCM and western medicine are being used in providing medical and health services in China. TCM, with its unique diagnostic methods, systematic approach, abundant historical literature and materials, has attracted many attentions from the international community. TCM is well recognized for its remarkable effectiveness in off setting the side effect caused by the toxic and chemical treatment of cancer cases in the western medical system.In China, TCM is under the administration of State Administration of TCM and Pharmacology. TCM and its development are regulated. National strategies, law and regulations governing TCM are now in place to guide and promote the research and development in this promising industry.TCM is defined as a medical science governing the theory and practice of traditional Chinese medicine. It includes Chinese medication, pharmacology/herbalogy, acupuncture, massage and Qigong.Hospitals in China are classified as specialized in western medical system, TCMor both. TCM is now available to 75% of the areas in China. TCM has been veryeffective in the treatment of diseases such as cardio-cerebro-vascular, immunogenic, tumors, bone fracture, etc. Scientificresearch and clinic experiments in TCM are continuously progressing. Successes have been made in many of the areas such as incirculating paths of meridians; in Zheng-syndrome, in diagnosticindexes; in therapeutic principles, in healing emergency patients with shock, acuteDIC, acute myocardial infarction and acute renal failure. For treatment of bone fracture, method is adopted based on the theory of combination of mobilization and immobilization. Non-antibacterial compound prescriptions are used successfully in treatment of bacterial infection. In treatment of cancers, Fuzheng Guben compound prescriptions, though devoidof inhibitory effects on cancer cells, could cause the shrink of the mass of cancer. TCM provides a non-surgical approach to the treatment of acute abdomen.CuppingCupping the source ofCupping therapy is a valuable heritage of Chinese medicine, one in Chinese Han people to use a long time. Ge Hong Jin Dynasty medical scientist with the "elbow back-up emergency party" where there are angle method documented. The so-called angle method is the use of hollowing out of the horns to pull abscess aspiration of foreign governing methods. Wang Tao of the Tang Dynasty "Taiwan Miyao,"also describes the use of bamboo cupping to cure, such as in the text, said: "... ...take three fingers Daqing bamboo, long Cunban, a left section, no section of the firstcut so thin like swords, cook the cheese Number of boiling,and heat out of cartridges, ink points according to the cage, a long time to break the corner cutter bombs, but also re-Kok, cook cheese, when a yellow and white Chishui, sub-a pus out, worm out there who。
谢锡亮教授直接灸法举隅
文章编号:0255-2930(2008)07-0527-02中图分类号:R249 文献标志码:A针家精要谢锡亮教授直接灸法举隅肖 杰1 王廷峰2(1.山西省侯马市澄江学派针灸研究所,山西侯马043001;2.新疆喀什市东方门诊部)[摘 要] 谢锡亮教授早年师从承淡安先生,从事针灸临床及教学60余年,学验俱丰,重视针、灸、药,因人而施,特别注重灸法,尤其是直接灸法,取穴少,作用广,疗效佳,操作方便,一次灸不过3～5min,还可教会患者及家人在家中自灸,省时省事。
灸法对免疫力低下患者及疼痛性疾病有较好的疗效,而且远期疗效亦佳,适于现代人治病、保健之用。
[关键词] 名医经验;灸法;感冒/针灸疗法;肝炎,乙型,慢性/针灸疗法Samples of professor XIE Xi-liang′s direct moxibustionX I AO J ie1,W AN G T ing-f eng2(1.Shanxi Pr ovince Houma City Institute o f A cupuncture and M o xibustion o f Chengjiang School,Shanxi Ho uma043001,China;K ashi City Dongfang O utpa tient Depar tment,Xinjiang)ABSTRAC T:pro f.X I E X i-liang in his early year s w as a disciple of M r.CH EN G Dan-an.H e has been engag ed in clinical wo rk and teaching fo r ov er60yea rs with rich experience,and he pay s attention to application of acupunc-ture,mo xibustion and medicine for different persons,especially pay s at tentio n to mo xibustio n methods,such as di-rect mo xibustio n,with less points selected,and go od results,convenient manipulatio n,moxibustio n o f o ne sessiononly for3-5min.He teaches the patients and their family fo r self-mox ibustion a t home,saving time.T his methodha s better sho rt-term and lo ng-term therapeutic effects fo r hypo-immune patients,pain diseases,and it is suitable to treatment of disease s and health-car e.KEY W ORDS:Famo us Doc to r′s Ex perience;M ox ibustion;Commo n Cold/am ther;Hepatitis B,Chro nic/am ther 山西省名老中医谢锡亮教授、主任医师,现年83岁,早年亲炙于近代针灸家承淡安先生,行医60余年,以医技精湛、医德高尚载誉三晋大地。
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• 253 •Chin J Integr Med 2012 Apr;18(4):253-255China has a long history of using Chinese medicine (CM) to treat chronic liver diseases. Today, CM is still one of the major medicines in China, and is also being used more commonly in Western countries. Chronic viral hepatitis B (CHB) is a global health problem. China has the largest population affected by this viral hepatitis. CHB is caused by infection with the hepatitis B virus (HBV). Chronic infection with HBV can signi fi cantly impair the quality of life and life expectancy of patients because of the potential for disease progression, which can lead to fi brosis, cirrhosis, liver failure and hepatocellular carcinoma. CM is used widely in CHB treatment in China as well as other countries. Clinical surveys revealed that over 90% of patients with CHB in China received CM therapy. More than 80% of natural products thought useful for management of liver diseases are Chinese herbs and/or their extracts, and over 80% of the Chinese publications regarding hepatitis and hepatic fi brosis are CM-related. These are far higher proportions than those for Western medicines used in China. In Western medicine, interferon (IFN) and lamivudine (LAM) or other nucleoside analogues (e.g. adefovir dipivoxil, tenofovir, entecavir) are the currently approved remedies for hepatitis B.Regarding the treatment CHB with CM, major questions are "Are CMs effective therapeutic agents for CHB? If yes, how to explain the large population infectedby HBV in China?" and "If they are, why are so many millions of Chinese chronically infected with the HBV?" There are both medical and cultural dimensions to these questions. In recent decades, a number of clinical trials have been performed in China to assess the efficacy and safety of CMs for CHB infection. Studies have looked at the effects of CMs on CHB, both alone, and in combination with Western medicines. Results have been compared with those from studies employing only conventional Western therapies.To understand better the current patterns of use of CMs in management of CHB in China, in 2010, we searched the database of the China National Knowledge Infrastructure (CNKI, from January 1998 to June 2008) and PubMed (January 1966 to June 2008) using the key words CM, herb, plant, herbal extract and hepatitis B. The reports of CM clinical trials that included prospective randomized clinical trials (RCTs), non-randomized clinical trials (non-RCTs), and summaries of clinical experience were selected for analysis. The clinical trials included single blind, double blind or not blinded studiesFEATURE ARTICLEChinese Medicine for Treatment of Chronic Hepatitis BGuqi WANG, Lingyi ZHANG, and Herbert L. Bonkovsky©The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag Berlin Heidelberg 2012Carolinas Medical Center, Charlotte, NC, 28203 USACorrespondence to: Dr. Guqi WANG, Tel: 704-355-8051, Fax: 704-355-1679, E-mail: guqi.wang@ DOI: 10.1007/s11655-012-1064-4ABSTRACT Contemporary Western medicines approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis B (CHB), although available in China, have high costs, or major side effects and limited effectiveness. Research efforts have focused on looking for natural products as alternative medicines with low cost and good safety for CHB treatment. Chinese medicine (CM) has ancient, time-honored theories about methods of diagnosis and treatment for liver diseases. In recent decades, a large number of clinical trials and pre-clinical studies, which were performed in China and other countries, indicated that CM has potential bene fi t in several aspects of the treatment of CHB, e.g., anti-in fl ammatory, anticancer, antioxidant, immunomodulating, anti fi brosis, and antiviral. However, there are many concerns regarding the study design and the quality of clinical trials. Furtherlarger, stringently designed, double-blind, placebo control, randomized clinical trials and long-term follow-up are needed to provide conclusive evidence of their ef fi cacy and safety. Components of CM deserve further study in pre-clinical models of HBV infection and in clinical trials world-wide.KEYWORDSchronic hepatitis B, natural products, Chinese medicine, Western medicine, clinical trialDr. Guqi WANG• 254 •Chin J Integr Med 2012 Apr;18(4):253-255in humans that involved CMs only versus IFN or LAM, and CMs plus IFN or LAM versus IFN or LAM treatment. We also statistically determined which individual herbs were used most frequently in CM formulations used to treat CHB. The results of our analysis were published recently in Hepatology(1) under the title "Contemporary Clinical Research of Traditional Chinese Medicines for Chronic Hepatitis B in China: An Analytical Review". Our major findings were as follows: (1) CMs reduced serum HBeAg and normalized serum ALT better than IFN, and were equivalent to IFN in clearing serum HBV DNA; (2) CMs plus IFN significantly reduced serum HBeAg, improved clearance of serum HBV DNA, and improved normalization of serum ALT, compared to IFN; (3) CMs were equivalent to LAM in reducing serum HBeAg, clearing serum HBV DNA, and normalizing serum ALT; (4) CMs plus LAM significantly reduced serum HBeAg, and were better at clearing the serum HBV DNA and normalizing serum ALT compared to LAM; (5) There were no serious adverse effects of CM reported in the clinical trials cited. Although the composition of traditional medicines in the CMs differed among RCTs, approximately 60% of the herbs were homologous. Our major overarching conclusion was that CMs seem effective as alternative remedies for patients with CHB, but they require further evaluation in well-designed, adequately-powered prospective, controlled randomized trials.It has to be acknowledged that some of the studies were poorly designed, and the data analysis and presentation were of low quality. Overall, the methodological quality of the clinical trials was not high. 70% of the RCTs included in our review were scored as having mediocre methodological quality. No trial was identified as a multi-center, large-scale, prospective, double-blinded, controlled randomized trial. Furthermore, only 24% of the RCTs performed long-term follow up studies. The possibility of publication bias in the reporting of results of clinical trials is always of concern. The purported effectiveness of CM formulations on CHB could be exaggerated if only positive results were published in the literature. Although the funnel plots in our study suggest that there was not major publication bias, there are still many other concerns remaining that include the following: the importance that investigators submit, and that journal editors publish, negative, as well as positive results; whether the RCTs were done by CM practitioners or Western medicine practitioners, and were approved by Chinese medical administration; how commonly Chinese Western medicine practitioners use those CMs in their clinical practice for HBV; there were many CM formulations used in these RCTs, what is the common standard or criterion to select the formulation for the RCT? The quality assurance and quality control of the CM formulations used in the clinical trials were generally not studied; there were few data available regarding the safety of the CM formulations used in these RCTs, although no side effects were reported in these studies, which suggest the formulations used were safe. All these concerns and the rather low quality of the RCTs make it difficult for clinicians to draw firm conclusions about the usefulness of CM.Our study also revealed that the CMs used for HBV treatment in different formulations are very similar. The most commonly used herbs include Radix Astragali (Huangqi), Radix Salviae Miltiorrhizae (Danshen), Rhizoma Polygoni Cuspidati (Huzhang), and Herba Hedyotis diffusae (Bai Hua She She Cao). Interestingly, milk thistle (Shui Fei Je), which is widely used for viral hepatitis and other liver diseases in Europe and North America, was not ranked in the top 20 most commonly used clinical herbs, suggesting that CM practitioners choose herbs for HBV mainly based on CM theory. Like CMs, milk thistle and its extracts (e.g., silymarin) have been used for medicinal purposes since the time of ancient Greece, and continue to attract attention for their touted liver-health properties. Although some studies reported successful treatment of patients infected with HBV with milk thistle, these finding were not replicated in higher quality clinical trials.(2) The U.S. Agency for Healthcare Research and Quality reported in a systematic review of clinical trials of milk thistle that milk thistle improved liver function in people with mild liver disease but did not work as well for those with severe liver disease such as cirrhosis. According to the National Center for Complementary and Alternative Medicine of the U.S. National Institutes of Health, milk thistle may benefit the liver by protecting and promoting the growth of liver cells, fighting oxidation (a chemical process that can damage cells), and inhibiting inflammation in laboratory animal studies.The art of Chinese medicine emphasizes the whole human body as a unit, and then uses a formula with several herbs, which are selected based upon the individual properties of the herbs and their purported ability to work in a complementary fashion to treat a disease in numerous domains. Hundreds of herbs have• 255 •Chin J Integr Med 2012 Apr;18(4):253-255been used in hundreds of dissimilar formulas of CMs for hepatitis B treatment. For example, typical strategies of CM treatment in CHB are (1) to relieve the symptoms and improve life quality of the patients; (2) to ameliorate liver infl ammation; (3) to ameliorate hepatic fi brosis; (4) to improve immune function; and (5) to regulate lipid metabolism. The purported health benefi ts are believed to be due to the intricate combining and interaction of these ingredients, and the prescription according to the individual patient's "pattern" (Zheng). Radix Astragali is mostly used to improve immune activities and replenish qi. Radix Salviae Miltiorrhizae is used to promote blood fl ow and remove blood stasis with anti-fi brosis; Rhizoma Polygoni Cuspidali is used to remove heat, dampness and toxic substances from the body and to promote blood circulation with anti-virus. Herba Hedyotis diffusae is used as an antipyretic, detoxicant, diuretic and anticancer agent. However, from a Western viewpoint of clinical analysis or research design, the time-honored CM approach complicates attempts to determine which ingredients are responsible for particular physiological effects. Moreover, the unique theoretical system and protocols of CM have created obstacles to communication with Western investigation. It is understandable that the protocol and standard of Western medicine may not be applicable to CM clinical trial.(3) Nevertheless, end-points of trials for treatment of CHB are similar: amelioration of hepatic infl ammation and fibrosis; reduction of levels of HBV in liver and serum; prevention of hepatocellular carcinoma; and improvement in and prolongation of life of good quality.Having been used for thousands of years in China, some healing properties of herbs are being confirmed by modern scientific methods. For example, one of the extracts from Radix Astragali, TAT2 (cycloastragenol) is reported to boost telomerase production and help immune cells fi ght HIV.(4) However, many Chinese herbs and herb formulations have still not been studied and examined by contemporary scientific methods. There is no convincing evidence from recent basic and clinical research to conclude that CM has better antiviral activity than IFN, LAM, and other modern antiviral drugs. Even though CM physicians and researchers suggest that CM promises some therapeutic effects in the treatment and prevention of liver fibrosis consequent to HBV infection by either enhancing immune activity or reducing liver inflammation,(5) some of the results are still based on the evaluation using CM protocols and the improvement in symptoms perceived by participants. Whether the hepatitis B patients receiving CM treatments have reduced risk to develop liver fi brosis and cirrhosis require further studies with long-term follow-up.According to the data of the World Health Organization (WHO), approximately 2 billion people worldwide have been infected with HBV, and more than 350 million have chronic (long-term) liver infections. There is no specific treatment for acute hepatitis B. Although the virus can be cleared in some patients by antiviral drugs, many strains are resistant to treatment, the drugs are expensive, and the side effects are serious. Research efforts have focused on looking for alternative therapies to curb symptoms with minimal side effects. The advantages of CM, such as time-honored of use, multiple targets, integrative medicine therapy (integrating with Western medicine), and affordable cost make them worthy of further rigorous scientific study, especially in China.(6) The possible antiviral, antiinflammatory, and antifibrogenesis mechanisms of these CMs deserve additional study with modern scientific technologies. Clarification of adverse effects and high quality clinical trials are required. Such studies will provide important information for drug development in combating viral hepatitis.REFERENCESZhang L, Wang G, Hou W, Li P, Dulin A, Bonkovsky HL.1.Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China: an analytical review. Hepatology 2010;51:690-698.Rambaldi A, Jacobs BP, Iaquinto G, Gluud C. Milk thistle 2.for alcoholic and/or hepatitis B or C liver diseases–a systematic cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Am J Gastroenterol 2005;100:2583-2591.Zhu LL, Meng H, Jiang J, Gao YQ. Study on traditional 3.Chinese medicine syndrome typing of chronic hepatitis B.Chin J Integr Tradit West Med (Chin) 2008;28:20-23.Fauce SR, Jamieson BD, Chin AC, Mitsuyasu RT, Parish ST, 4.Ng HL, et al. Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes. J Immunol 2008;181:7400-7406.Hu YY. Traditional Chinese medicine treatment of hepatic 5.fibrosis and its characteristics. Chin J Integr Tradit West Med (Chin) 2006;26:10-11.Liu P. Play superior role of integrative medicine thought 6.for further improving clinical efficacy of traditional Chinese medicine against hepatic fibrosis. Chin J Integr Tradit West Med (Chin) 2006;26:7-8.(Received February 7, 2012)Edited by ZHANG Wen。