A RECOMBINANT AASTANARG532009 M-13-09D FLU VI
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专利名称：A RECOMBINANT A/ASTANARG/5:3/2009 M-13-09/D FLU VIRUS STRAIN PRODUCED BY A
REVERSE GENETICS METHOD FROM A
HIGHLY PATHOGENIC DONOR STRAIN
A/CHICKEN/ASTANA/6/05 (H5N1) AND A
HIGHLY REPRODUCTIVE DONOR STRAIN
A/PUERTO RICO/8/34 (H1N1) FROM THE
ORTHOMYXOVIRIDAE FAMILY OF THE
GENUS INFLUENZA VIRUS TYPE A WHICH IS
DEPOSITED IN THE MICROORGANISM
COLLECTION OF THE SCIENCE COMMITTEE
AT THE MINISTRY OF EDUCATION AND
SCIENCE OF THE REPUBLIC OF
KAZAKHSTAN STATE ENTERPRISE
SUBSIDIARY OF THE SCIENTIFIC RESEARCH
INSTITUTE FOR BIOLOGICAL SAFETY
PROBLEMS AT THE REPUBLICAN STATE
ENTERPRISE OF THE NATIONAL CENTRE
FOR BIOTECHNOLOGY OF THE REPUBLIC OF
KAZAKHSTAN AND CAN BE USED IN
BIOTECHNOLOGY FOR THE PRODUCTION
OF DIAGNOSTIC AND VACCINE
PREPARATIONS AGAINST A/H5N1 FLU
发明人：STROCHKOV, Vitaliy
Mikhailovich,СТРОЧКОВ, Виталий
专利内容由知识产权出版社提供
Михайлович,MAMADALIYEV, Seidigapbar
Mamadaliyevich,МАМАДАЛИЕВ
Сейдигапбар Мамадалиевич,KISILEV, Oleg
Ivanovich,КИСИЛЕВ, Олег
Иванович,SANDIBAEV, Nurlan
Tamambaevicvh,САНДЫБАЕВ, Нурлан
Тамамбаевич,KHAIRULLIN, Berik
Mukhitovich,ХАЙРУЛЛИН, Берик
Мухитович,TSYBALOVA, Ljudmila
Parkovna,ЦЫБАЛОВА, Людмила
Марковна,MAMBETALIEV,
Muratbai,МАМБЕТАЛИЕВ,
Мурагбай,KIDIRBAEV, Zhailaubai
Kidirbaevich,КЫДЫРБАЕВ, Жайлаубай
Кыдырбаевич,TABYNOV, Kaisar
Kazbibaevich,ТАБЫНОВ, Кайсар
Казыбаевич
申请号：KZ2010/000008
申请日：20100423
公开号：WO2011/074929A1
公开日：20110623
摘要：The invention relates to the field of biotechnology and gene engineering. The recombinant A/AstanaRG/5:3/2009 M-13-09/D flu virus strain is produced by a reverse genetics method from the strains A/chicken/Astana/6/05 (H5N1) and A/Puerto Rico/8/34 (H1N1) from the Orthomyxoviridae family of the genus Influenza virus type A. The strain, which has low virulence and high reproductive activity, is used for producing diagnostic
and vaccine preparations against A/H5N1 flu. The activity of the recombinant
A/AstanaRG/5:3/2009 flu virus strain in serological reactions is 1:4-1:8 in a diffusion precipitation reaction, 1:40-1:80 in a hemagglutination-inhibition test and 1:640 in immunofluorescent analysis.
申请人："REPUBLICAN GOVERNMENTAL ENTERPRISE ON THE RIGHT OF ECONOMIC MANAGEMENT "RESEARCH INSTITUTE FOR BIOLOGICAL SAFETY PROBLEMS" OF THE SCIENCE COMMITTEE OF THE MINISTRY OF EDUCATION AND SCIENCE OF THE REPUBLIC OF KAZAKHSTAN","РЕСПУБЛИКАНСКОЕ ГОСУДАРСТВЕННОЕ ПРЕДПРИЯТИЕ НА
ПРАВЕ ХОЗЯЙСТВЕННОГО ВЕДЕНИЯ "НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ
ПРОБЛЕМ БИОЛОГИЧЕСКОЙ БЕЗОПАСНОСТИ" КОМИТЕТА НАУКИ МИНИСТЕРСТВАОБРАЗОВАНИЯ И НАУКИ РЕСПУБЛИКИ КАЗАХСТАН",STROCHKOV, Vitaliy Mikhailovich,СТРОЧКОВ, Виталий Михайлович,MAMADALIYEV, Seidigapbar Mamadaliyevich,МАМАДАЛИЕВ Сейдигапбар Мамадалиевич,KISILEV, Oleg Ivanovich,КИСИЛЕВ, Олег Иванович,SANDIBAEV, Nurlan Tamambaevicvh,САНДЫБАЕВ,Нурлан Тамамбаевич,KHAIRULLIN, Berik Mukhitovich,ХАЙРУЛЛИН, Берик
Мухитович,TSYBALOVA, Ljudmila Parkovna,ЦЫБАЛОВА, Людмила
Марковна,MAMBETALIEV, Muratbai,МАМБЕТАЛИЕВ, Мурагбай,KIDIRBAEV, Zhailaubai Kidirbaevich,КЫДЫРБАЕВ, Жайлаубай Кыдырбаевич,TABYNOV, Kaisar Kazbibaevich,ТАБЫНОВ, Кайсар Казыбаевич
地址：080409 KZ,080409 KZ,080409 KZ,080409 KZ,080409 KZ,080409 KZ,197376 RU,197376 RU,080409 KZ,080409 KZ,080409 KZ,080409 KZ,197376 RU,197376 RU,080409 KZ,080409 KZ,080409 KZ,080409 KZ,080409 KZ,080409 KZ
国籍：KZ,KZ,KZ,KZ,KZ,KZ,RU,RU,KZ,KZ,KZ,KZ,RU,RU,KZ,KZ,KZ,KZ,KZ,KZ
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