3-异氰酸酯基丙基三甲氧基硅烷

Product name: SILQUEST® A-LINK(TM) 35 SILANE1. PRODUCT AND COMPANY IDENTIFICATIONProduct name:SILQUEST® A-LINK(TM) 35 SILANEChemical name:Gamma-IsocyanatopropyltrimethoxysilaneSupplier:GE Silicones3500 South State Route 2Friendly, WV 26146, USAContact numbers:CHEMTREC (24 hours): 800-424-9300GE Silicones Emergency Response (24 hours): 800-809-9998GE Silicones Emergency Response (24 hours): 304-926-8418For Product Safety Inquiries: 304-652-8446For MSDS only: 304-652-8155Customer Service: 800-523-58622. COMPOSITION / INFORMATION ON INGREDIENTSC OMPONENT CAS#C ONCENTRATION Isocyanatopropyltrimethoxysilane15396-00-6> 95.0 % Aminoalkylsilane ester derivative Trade secret< 5.0 % Methanol67-56-1< 0.5 %Note(s):Additional methanol may be formed by reaction with moisture.See Section 15 for chemicals appearing on Federal or State Right-To-Know lists.3. HAZARDS IDENTIFICATIONEMERGENCY OVERVIEWDANGER!HARMFUL OR FATAL IF SWALLOWED.CAUSES EYE AND SKIN BURNS.CORROSIVE IF SWALLOWED.HARMFUL IF INHALED.HARMFUL IF ABSORBED THROUGH SKIN.MAY CAUSE EYE DAMAGE AND BLINDNESS IF SWALLOWED.ASPIRATION MAY CAUSE LUNG DAMAGE.MAY CAUSE ALLERGIC RESPIRATORY OR SKIN REACTION.MAY CAUSE DIZZINESS AND DROWSINESS.MAY CAUSE HEART MUSCLE DAMAGE.MAY CAUSE LIVER AND KIDNEY DAMAGE.Product name: SILQUEST® A-LINK(TM) 35 SILANE4. FIRST AID MEASURESSwallowingIf patient is fully conscious, give two glasses of milk or water at once.Do not induce vomiting.Obtain medical attention immediately.SkinImmediately remove contaminated clothing and shoes.Wash skin with soap and water.Obtain medical attention.Wash clothing before re-use.Discard contaminated leather articles such as shoes and belt.InhalationRemove to fresh air.Give artificial respiration if not breathing.If breathing is difficult, oxygen may be given by qualified personnel.Obtain medical attention.Eye contactImmediately flush eyes with water and continue washing for at least 15 minutes.Obtain medical attention without delay, preferably from an ophthalmologist.Notes to physicianDue to the irritating nature of the material, any aspiration during vomiting could result in severe lung injury. Therefore, emesis should not be induced mechanically or pharmacologically. This product reacts with moisture in the acid contents of the stomach to form methanol. The combination of visual disturbances, metabolic acidosis, and formic acid in the urine is evidence of methanol poisoning. The therapeutic intravenous administration of ethanol (10 ml per hour) allows it to be preferentially oxidized and reduces production of methanol metabolites. Acidosis must be treated by means of intravenous sodium bicarbonate, and methanol elimination may be increased by hemodialysis, as indicated. Treatment should be based on blood methanol levels and acid-base balance. Folates may be administered to enhance the metabolism of formaldehyde. 4-Methyl pyrazole has been suggested as an antidote: because of its alcohol dehydrogenase inhibiting effects, it reduces the production of formate and the development of metabolic acidosis. However, the value of this antidote remains to be proven in humans.5. FIRE-FIGHTING MEASURESFlash point:99 °C (210 °F)Flammable limitsLower limit:Not availableUpper limit:Not availableSpecial fire fighting proceduresNone.Special protective equipment for firefightersSelf-contained breathing apparatus. Body covering protective clothing.Extinguishing mediaSuitable:Large fires:- alcohol-type foam or universal-type foamsSmall fires:- CO2- dry chemicalProduct name: SILQUEST® A-LINK(TM) 35 SILANEUnsuitable:None.Unusual fire and explosion hazardsNone known.6. ACCIDENTAL RELEASE MEASURESPersonal precautionsAvoid contact with eyes and skin.Avoid contact with liquid and vapors.Wear suitable protective equipment. Environmental precautionsPrevent runoff.Methods for cleaning upCover with absorbent or contain.Collect for disposal.Observe government regulations.7. HANDLING AND STORAGEHANDLINGHandling precautionsDo not breathe vapor. Do not swallow. Do not get in eyes, on skin, on clothing. Use only with adequate ventilation. Wash thoroughly after handling. Workers sensitized to other isocyanates should not handle this material.Other precautionsDANGER!Harmful or fatal if swallowed due to methanol production in the stomach.STORAGEStorage requirementsKeep container closed.8. EXPOSURE CONTROLS / PERSONAL PROTECTIONPERSONAL PROTECTIONRespiratory protectionSelf-contained breathing apparatus in high vapor concentrations.Hand protection / protective glovesRecommended order of use:4HButylNeopreneNitrile (NBR)PVC-coatedProduct name: SILQUEST® A-LINK(TM) 35 SILANEEye protectionMonogogglesSkin protectionChemical protective clothing.Other protective equipmentEye bathSafety showerENGINEERING CONTROLSVentilationGeneral (mechanical) room ventilation is expected to be satisfactory where this product is stored and handled in closed equipment.Special, local ventilation is needed at points where vapors can be expected to escape to the workplace air. EXPOSURE LIMITSComponent Type Value Remark Methanol TWA (skin), OSHA200.0 ppmSTEL (skin), ACGIH250.0 ppmTWA (skin), ACGIH200.0 ppm9. PHYSICAL AND CHEMICAL PROPERTIESAPPEARANCEPhysical state LiquidColor Clear, paleOdor SlightOTHER PROPERTIESBoiling point> 200 °C at STP unless specified below.MixtureMelting point< 0 °C at STP unless specified below.pH Not availableSpecific gravity (H2O=1) 1.0730at 25 °C ( 1,013 hPa)Vapor pressure< 1.33 hPa(1.00 mmHg)at 20 °CVapor density (air=1)Heavier than airSolubility in water Reacts slowlyEvaporation rate (Butyl < 1Product name: SILQUEST® A-LINK(TM) 35 SILANEAcetate=1)Flash point99 °C (210 °F)Method:Pensky-Martens closed cup ASTM D 93Upper explosion limits Not availableLower explosion limits Not availablePercent volatiles Not determinedMolecular weight Mixture10. STABILITY AND REACTIVITYStability: Stable.Stability - Conditions to avoidAlkalis.Incompatible materialsAlcohols.Oxidizing agents.Reacts violently if combined with:Alkalis.Reacts with water or moisture to form:Methanol.Hazardous combustion productsBurning can produce the following combustion products:Oxides of carbon.Oxides of nitrogen.Oxides of silicon.Carbon monoxide is highly toxic if inhaled; carbon dioxide in sufficient concentrations can act as an asphyxiant. Acute overexposure to the products of combustion may result in irritation of the respiratory tract.Hazardous polymerization: Will not occur.Hazardous polymerization - Conditions to avoidNone known.11. TOXICOLOGICAL INFORMATIONSWALLOWINGAcute effectsSlightly toxic.Causes severe irritation or chemical burns.Affects:- mouth, throat, esophagus and stomachThis product hydrolyzes in the stomach to form methanol.Methanol may cause nausea, abdominal pain, vomiting, headache, dizziness, shortness of breath, weakness, fatigue,Product name: SILQUEST® A-LINK(TM) 35 SILANEleg cramps, restlessness, confusion, drunken behavior, visual disturbances, drowsiness, coma, and death. There may be a delay of several hours between swallowing methanol and the onset of signs and symptoms. The effects observed are in part due to acidosis and partially to cerebral edema. Visual effects include blurred vision, diplopia, changes in color perception, restriction of visual fields, complete blindness. Ingestion of moderate quantities of methanol also produces metabolic acidosis. Onset of symptoms may be delayed up to 48 hours. 60-200 ml methanol is fatal dose for most adults. Ingestion of as little as 10 ml methanol has caused blindness. With massive overdoses, liver, kidney and heart muscle injuries have been described.Test resultsAcute toxicity:LD50-RatResult: 878 mg/kgRemark:Slightly toxic.SKIN ABSORPTIONAcute effectsSlightly toxic.Prolonged and/or widespread contact may result in:- absorption of potentially harmful amounts of materialTest resultsAcute toxicity:LD50-RabbitResult: 1,190 mg/kgRemark:Very low to slightly toxicINHALATIONAcute effectsCauses irritation of the respiratory tract.Causes the following effects:- nasal discomfort and discharge- chest pain- coughingHigh concentrations of vapor may result in the inhalation of harmful amounts of material.SKIN CONTACTAcute effectsCauses severe irritation.Causes the following effects:- discomfort or pain- marked local redness- swelling- corrosionTest resultsSkin irritation:Species:RabbitResult:Corrosive.EYE CONTACTAcute effectsCauses severe irritation.Effects from fluid contact:- discomfort- painProduct name: SILQUEST® A-LINK(TM) 35 SILANE- excess blinking- tear production- marked excess redness of the conjunctivae- swelling of the conjunctivae- chemical burns of the corneaVapor may cause moderate to severe irritation.Effects from vapor contact:- discomfort- excess blinking- tear production- excess redness of the conjunctivae- swelling of the conjunctivaeTest resultsEye irritation:Species:RabbitResult:Severe irritation, corneal injuryMedical conditions aggravated by overexposureMay aggravate:- an existing kidney disease- an existing liver diseaseSkin contact may aggravate:- an existing dermatitisVapor/Mist may aggravate:- asthma and inflammatory or fibrotic pulmonary diseaseOther effects of overexposureThe following information is based on analogy with a similar material.Prolonged and/or repeated contact may result in:- sensitization- allergic skin reactionProlonged and/or repeated exposure may cause the following effects:- sensitization of the respiratory tractWorkers exposed to this product may be sensitized to other isocyanates.SIGNIFICANT DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTHThis material was tested in a bacterial mutagenicity assay (Ames test) and found to be weakly mutagenic.12. ECOLOGICAL INFORMATIONAll available ecological data have been taken into account for the development of the hazard and precautionary information contained in this Safety Data Sheet.13. DISPOSAL CONSIDERATIONSGeneral:Incinerate in a furnace where permitted under appropriate Federal, State, and local regulations.Product name: SILQUEST® A-LINK(TM) 35 SILANE14. TRANSPORT INFORMATIONDOT ClassificationProper shipping name:CORROSIVE LIQUID, N.O.S. (gamma-Isocyanatopropyltrimethoxysilane) Class:8UN ID #:UN1760Packing group:IIFreight description road:SIZING, NOIIMDG ClassificationProper shipping name:CORROSIVE LIQUID, N.O.S. (gamma-Isocyanatopropyltrimethoxysilane) Class:8UN ID #:UN 1760Packing group:IIICAO ClassificationProper shipping name:CORROSIVE LIQUID, N.O.S. (gamma-Isocyanatopropyltrimethoxysilane) Class:8UN ID #:UN 1760Packing group:II15. REGULATORY INFORMATIONComprehensive Environmental Response Compensation and Liability Act of 1980 (CERCLA) requires notification of the National Response Center of release of quantities of hazardous substances equal to or greater than the reportable quantities (RQ’s) in 40CFR302.4.Components present in this product at a level which could require reporting under the statute are:**** NONE ****Superfund Amendments and Reauthorization Act of 1986 (SARA) Title III requires emergency planning based on Threshold Planning Quantities (TPQ’s) and release reporting based on Reportable Quantities (RQ’s) in 40CFR355 (used for SARA 302 and 304).Components present in this product at a level which could require reporting under the statute are:**** NONE ****Superfund Amendments and Reauthorization Act of 1986 (SARA) Title III requires submission of annual reports of release of toxic chemicals that appear in 40CFR372 (for SARA 313). This information must be included in MSDS’s that are copied and distributed for this material.Components present in this product at a level which could require reporting under the statute are:**** NONE ****Massachusetts Right-To-Know Substance List (MSL)--Hazardous Substances and Extraordinarily Hazardous Substances on the MSL must be identified when present in products.Components present in this product at a level which could require reporting under the statute are:**** NONE ****Pennsylvania Right-To-Know Hazardous Substance List--Hazardous Substances and Special Hazardous Substances on the list must be identified when present in products.Components present in this product at a level which could require reporting under the statute are:**** NONE ****Product name: SILQUEST® A-LINK(TM) 35 SILANENew Jersey Worker and Community Right-To-Know Act (Labeling Requirements)Chemical name CAS#New Jersey TS Number Isocyanatopropyltrimethoxysilane15396-00-6Aminoalkylsilane ester derivative Trade secret NJ Reg# 26175-5719P EPA Hazard Categories (SARA 311, 312):Immediate Health Hazard, Delayed Health HazardCalifornia Proposition 65This product contains no levels of listed substances, which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute.California SCAQMD Rule 443.1 VOC’sVolatile Organic Components (VOC’s) = Substances with vapor pressure of => 0.5 mmHg at 104’C (219.2’F).This product contains 5.09 g/liter VOC’s.CHEMICAL INVENTORYUnited States:The components of this product are listed on the TSCA inventory or are exempt.Australia:This product, or the components, is listed or exempt from listing on the AustralianInventory of Chemical Substances (AICS).Japan:This product is not listed or exempt from listing on the Existing and New ChemicalSubstances (ENCS) list.Korea:This product is not listed on the Existing Chemicals List (ECL).Philippines:This product is not listed or exempt from listing on the Philippines Inventory ofChemicals and Chemical Substances (PICCS).16. OTHER INFORMATIONRECOMMENDED USES AND RESTRICTIONSPlease consult the product and/or application information bulletins for this product.HMIS RATINGHealth: 3Flammability: 1Reactivity: 2PPI: XLEGENDSTP Standard temperature and pressureW/W Weight/Weight0 (HMIS)Minimal hazard1 (HMIS)Slight hazard2 (HMIS)Moderate hazard3 (HMIS)Serious hazard4 (HMIS)Severe hazardX (HMIS)Personal protection rating to be supplied by user depending on use conditionsThe opinions expressed herein are those of qualified experts within GE Silicones. We believe that the information contained herein is current as of the date of this Safety Data Sheet. Since the use of this information and of theseProduct name: SILQUEST® A-LINK(TM) 35 SILANEopinions and the conditions of use of this product are not within the control of GE Silicones, it is the user’s obligationto determine the conditions of safe use of the products.。