我的医学专业英语论文

Summary ofTheAtrial

FibrillationStudyProgress

Abstract:Atrial fibrillation (AF) is the most commoncardiac arrhythmia,andarrhythmiafield ofthe most difficultto overcomeoneoftheheart disease. Chinaisthelargest country intheworldonpatients with atrial fibrillation, withtheimprovementofpeople's living standardand population aging, the incidence rateshowed an increasingtrendandbecomethe 21st centuryChina's emergingmainstreamof cardiovascular disease. Althoughatrial fibrillationis notlikeVFwill have a directcause of death in patients, but therapidventricular rateinatrial fibrillationcan causehemodynamic deterioration, resulting in cardiacdysfunctionandmalignant ventricular arrhythmias, especially combinedthrombosiswill begreatly increasedin patients withtherisk of stroke. Effectivetestmethodcannotfindthetrackstate changesofatrial fibrillationandtreatmentof atrial fibrillationtreatmentare basicallybasedontheclinicaltrial and error, leading to thedeclineintreatmentefficiency.In this paper, througha synthesis ofmodern researchonatrial fibrillation (AF), provideamore scientificbasistounderstandthe hazardsofatrial fibrillationandatrial fibrillationdiagnosis and treatment.

Key words: atrial fibrillationmechanism ESC OSAS

New understanding of atrial fibrillation mechanisms

Based on extensive research in recent years, clinical and basic, the ESC released a new atrial fibrillation treatment guidelines detailed mechanisms of atrial fibrillation: atrial factor (atrial pathophysiology, such as atrial enlargement or fibrosis), electrophysiological mechanism (focal excited or reentrant, multiple micro-reentry, etc.), genetic factors (such as the cardiac sodium channel gene SCN5A adjustment function missing, etc.), clinically relevant factors (eg, hemodynamic changes) [1].

New risk factors: obesity and OSAS

Obese patients with atrial fibrillation, the average body mass index (BMI) was 27.5 kg/m2, equivalent to when the moderately obese [3]. Overweight and obesity can affect the atrial and ventricular structure and diastolic function, autonomic nerve function, suggesting a clear link between obesity and atrial fibrillation. The data show that obese people with atrial fibrillation relative risk is 1.5 times the normal individuals, and each increase in BMI to 1 kg/m2, the relative risk of atrial fibrillation increased by 4% [4].

Sleep-disordered breathing sleep apnea syndrome (OSAS) increase atrial pressure or excessive changes of autonomic tone can trigger atrial fibrillation. Repeated hemodynamic and hypoxic fluctuations can also activate the stretch sensitivity of ion channels and (or) catecholaminergic channel, resulting in a more active focal excited. OSAS associated with vagal reflex as a symbol (bradycardia) can lead to pulmonary vein antrum should not shorten the trigger focal excited. OSAS and elevated C-reactive protein is independently associated with cause of atrial fibrillation relative risk increase. Studies have shown that the prevalence of atrial fibrillation in patients with OSAS was significantly