兰州大学病理学和病理生理学2019年考博真题考博试卷
兰州大学考研真题(已有10试题)
兰州大学管理学院管理学2000——2006西方经济学2000——2007，2010（2010为回忆版）文学院古代汉语和现代汉语2006古代汉语2002——2005文学概论2000——2002，2004——2005现代汉语2002现代汉语和语言学概论2003——2005语言学概论2000——2002中国文学2008中国文学史2000——2007（注：2002，2003年试卷名称为“中国古代文学史”）中国现代文学史2002——2003文学理论和外国文学2008文学概论和外国文学2006比较文学与世界文学2002——2003汉语言文字学2000——2001新闻与传播学院传播学原理1999——2005（1999——2004有答案）新闻理论(含中国新闻事业史) 1999——2005，2007（1999——2004有答案）新闻写作1999——2002历史文化学院民族学概论2003——2005民族学原理2000——2001世界近现代史1995——2005中国古代史2000——2005中国近现代史1994——2005中国历史文选2002——2005中国少数民族史2003——2005经济学院高级微观与宏观经济学2006西方经济学2000——2007，2010（2010为回忆版）发展经济学2000——2005金融学综合（含货币银行学、国际金融学）2005政治经济学（资、社）2000——2005中国近现代经济史(含中国近代经济史、中华人民共和国经济史)2005法学院法理学2003——2005法理学（复试）2004国际公法（复试）2004——2005国际经济法2005环境与资源保护法2002——2005经济法2001——2005民法2001——2002民法（复试）2004——2005民商法2003——2005民事诉讼法（复试）2004——2005宪法与行政法学2008宪法（复试）2004刑法2004——2005刑事诉讼法（复试）2004——2005行政法2002行政法与行政诉讼法2004——2005外国语学院二外德语2002——2005二外法语2002——2005二外日语2001，2003（2001有答案）翻译与写作2004——2005英美文学2001——2005英语语言学2002——2005哲学社会学院科学思想史2004——2005马克思主义哲学2004——2005西方哲学史2000——2005中国哲学史2000——2005社会调查方法2002——2005（注：2004年试卷共2页，缺第2页）社会学理论2007社会学概论2002——2005社会学专业2004年复试（笔试）试题政治与行政学院国际政治学2002——2006，2008（注：2008年试卷为回忆版）马克思主义发展史2002——2006政治学原理2002——2006，2008科学社会主义原理2004教育学院高等教育学2002教育基本理论（含中外教育史）2003——2005教育心理学2002心理学2003——2005中外教育史2002数学与统计学院高等代数2001——2006，2008（答案有：2008）数学分析1999——2006，2008（答案有：2005）物理科学与技术学院半导体物理1998——2000，2002——2005高等数学(物理类)2001——2005固体物理2003——2005量子力学(含原子物理学)2001——2005原子核物理(含核物理实验方法)2003——2005信息科学与工程学院高等数学(物理类)2001——2005电子线路（含线性电路、数字电路与逻辑设计）2000——2005计算机组成原理2002数据结构A2002操作系统2002数据结构A(含操作系统)2003——2005数据结构（含操作系统、计算机组成原理）2007数据结构B(含计算机组成原理)2003——2005化学化工学院分析化学（含无机化学）2001——2002，2001——2002答案化工原理2005，2005答案（其中2005答案缺第3页）无机化学1993——1998，2001，2001答案（其中2001答案缺页）无机及分析化学1999——2000，2002——2005，2002——2005答案物理化学1993——2004，2001——2004答案物理化学A2005，2005答案物理化学B2005，2005答案有机化学1993——2005，2001——2005答案（其中2005年的试卷缺第一页）生命科学学院分子生物学2003——2005普通动物学（含脊椎动物学、无脊椎动物学）2002——2005普通微生物学2004——2005生理学2002——2005生态学(含种群生态学、群落生态学、生态系统生态学)2002——2005生物化学(含有机化学)2002——2005，2007细胞生物学2003——2005，2007遗传学(含分子遗传学)2002——2005植物生物学（含植物生理学）2002——2005，2007资源环境学院自然地理学2000——2006高等数学（地学类）2000——2006环境学概论2002——2006普通地质学2001——2005岩石学(沉积岩和岩浆岩)2000——2005遥感与地理信息系统2002——2005草地农业科技学院普通生态学2003——2005土壤学2005植物生理学2003——2005大气科学学院高等数学(物理类)2001——2005土木工程与力学学院（无此试卷）艺术学院（无此试卷）医学院（原兰州医学院）病理生理学2001病理学2001——2004（其中2001年有两种）生理学1997——2000，2005。
考博病理试题
1999年名词解释：1 torch 2 stump carcinoma 0f cervix 3 contraception问答题：1 输卵管炎的发生和发展2 产褥感染的诱因和病原体3 manning 物理生物相4 持续枕后位的原因和处理5 排卵性宫血的处理6 宫内节育器的副作用7 宫颈癌手术治疗1b-2a期的手术范围8 卵巢癌的高危发病因素和组织分类2000年名词解释：微灶浸润癌输卵管卵巢囊肿问答题：1 妊高征对于母儿的影响和预防。
2 前置胎盘的处理原则3 阴道出血的原因和明确诊断4 内异症的现代治疗进展5 恶性卵巢肿瘤的鉴别诊断和处理原则6 卵巢早衰的病理机制和病理分型7 口服避孕药的改良和效果8 多胎妊娠的临床表现和治疗2005年病理妇产博士(注：总论分值一般占到70-80%)一、名词解释（6~15非病理专业答）1、干线性肝硬变2、羽毛状坏死3、疣状癌4、 Wilms瘤5、 Gastrinoma6、早期胃癌7、毛玻璃样肝细胞8、脂性肾病9、软化灶10、粒细胞肉瘤11、新月体12、点状坏死13、 paraneoplasic syndrome14、嗜酸性小体15、硬性下疳二、问答题（3~7非病理专业答）1、何谓Burkitt淋巴瘤，试述其病理变化、免疫表型及分子遗传特点。
2、原始神经上皮肿瘤（primitive neuorectodermal tumor PNET）的特点是什么，列举中枢神经系统来源的PNET，并描述其光镜特征。
3、非毒性甲状腺肿不同时期的病理改变有何特点。
4、简述各种肾小球肾炎免疫荧光沉积部位、方式和类型。
5、引起肺心病的疾病有哪些，他们的共同病理特点是什么，肺心病病理诊断标准是什么。
6、在结节性肝硬变形成过程中，肝内血管会发生哪些改建，可能对机体产生哪些影响。
7、一成年女性发现右乳腺外上方有一结节性肿物，直径约2.5cm，试举三种性质完全不同，需鉴别诊断的疾病，简述其镜下的主要诊断要点。
医学博士生考试真题
医学博士生考试真题选择题下列哪种细胞是构成人体免疫系统的主要细胞？A. 神经细胞B. 红细胞C. 淋巴细胞D. 肌细胞答案：C在医学研究中，下列哪种方法常用于评估药物的治疗效果？A. 问卷调查B. 随机对照试验C. 观察法D. 文献回顾答案：B下列哪种疾病是由病毒引起的？A. 糖尿病B. 冠心病C. 流行性感冒D. 骨质疏松症答案：C在解剖学上，心脏的主要功能是什么？A. 分泌激素B. 储存血液C. 泵送血液D. 消化食物答案：C下列哪种激素由甲状腺分泌，对机体代谢和生长发育有重要作用？A. 胰岛素B. 生长激素C. 甲状腺素D. 肾上腺素答案：C名词解释肝肾综合征（HRS）：又称功能性肾衰，以自发性少尿或无尿、氮质血症、稀释性低钠血症和低尿钠为特征，而肾脏无明显病理改变。
肠易激综合征（IBS）：是一种腹痛或腹部不适伴排便习惯改变为特征的功能性肠病，经检查排除可引起这些症状的器质性疾病。
卓-艾综合征（胃泌素瘤）：由胰腺非β细胞瘤分泌大量胃泌素所致，肿瘤一般很小（<1cm），生长缓慢，半数为恶性。
简答题自发性气胸的治疗原则：根据气胸类型、病因、发生频次、肺萎缩程度、病情状态及有无并发症等，酌情选择保守治疗或手术治疗。
一般首次发生的症状较轻的闭合性气胸，可先行保守治疗。
保守治疗无效或复发、引流后持续漏气、血气胸、长期气胸、张力性气胸引流失败者可考虑手术治疗。
支气管哮喘典型的临床表现：反复发作性伴有哮鸣音的呼气性呼吸困难。
症状可在数分钟内发生，并持续数小时至数天，可经平喘药物治疗后缓解或自行缓解。
夜间及凌晨发作和加重常是哮喘的特征之一。
肿瘤外科治疗的原则：无瘤原则：指在切除肿瘤时及整个手术过程中，防止肿瘤细胞的扩散和种植，这是肿瘤外科治疗的基本原则。
整块切除原则：强调在手术中应整块切除肿瘤及其周围正常组织，以防止肿瘤细胞的扩散。
根治性原则：在切除肿瘤时，应同时切除肿瘤周围可能受累的淋巴结和软组织，以达到根治的目的。
南开大学病理生理学2019年考博真题考博试卷
医学考博真题试卷
南开大学医学院
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2019 年攻读博士学位研究生学考试试题
考试科目：病理生理学 注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
一、名词解释 代谢性碱中毒 肝性脑病 低钾血症 二、简答题 1 高钾血症酸碱代谢失衡的类型及心肌电生理特点 2MODS 的组织和代谢变化 3 肝纤维化的发病机制 4 肺换气功能障碍的类型和机制 5 全身缺氧的代偿和损伤变化 三、论述题 1 休克器官功能障碍的细胞机制 10 分 2 细胞功能障碍的方式，心血管疾病和肿瘤试述 15 分 3 缺血再灌注钙超载的作用机制 15 分 4 体液因素在损伤中的的作用方式简述，外泌体在衰老和肿瘤中的作用方式，机制 15 分
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博士病理学统考历年试题
2005一、简答题（20）：1.肿瘤的定义，肿瘤与反应性增生的区别和联系。
2.乙性脑炎的镜下病理改变。
3.乳头状甲状腺癌的病理特点。
4.列举导致心、肺、肠、脑等坏死的疾病，及坏死类型。
二、论述题（40）：1.举例五种肉芽肿性疾病，病理特点及具有诊断价值的病理改变。
2.原发性肺结核的病变特点、病理变化过程、预后。
3.病例分析：一个典型的慢性支气管炎--肺气肿--肺心病--合并上呼吸道感染--右心衰的病变过程，病理变化与临床表现的联系。
4.多在半年内可痊愈的肝炎，问其属于哪一型肝炎？结合病理特点，分析为何可在半年内痊愈•国家医学考考试中心2006年病理学（博士统考题）简答1：1、goodpasture综合症，机制，特征，临床表现。
2、简述粥样硬化及其继发改变。
3、凋亡/坏死形态区别4、慢性组塞肺气肿的发病机制。
问答题：1、肿瘤转移概念，途经及特点2、细胞缺氧的损伤机制3、什么是栓塞，栓塞的后果。
4、纤维素性炎好发部位是什么，各部位基本特征及其结局多选题：肝硬化原因，造成肾小球基膜增厚的慢性肾小球肾炎的类型，混合血栓组成，慢性阻塞性肺炎特点哮喘的病理特点B型题（6题）colon病的好发位置肠结核的好发位置肠伤寒的好发位置单选题：（只记得不会的）3个胚胎层起源的是畸胎瘤2008年博士生入学考试病理学考试题（全国统考）一、选择题（每题1分，共40分）A型题1-21题1.肿瘤的淋巴道转移首先出现在2.显示淀粉样变性的特殊染色3.可导致DIC的是4.槟榔肝可发展成为5.引起脾、肾、肺梗死的常见原因6.哪个部位假膜性炎能对机体产生严重后果7.颈部淋巴结肿大，病理活检查见乳头状结构，最可能是8.诊断高分化鳞状细胞癌的主要根据9.属于恶性肿瘤的是10.狼疮性肾炎最常见组织类型11.乳房的TNM分期12.乳房橘皮样外观常见于13.子宫早期浸润癌是指14.肾细胞癌可能出现的临床表现15.甲状腺髓样癌的组织来源16.膜增生性肾小球肾炎的主要病变17.不属于乙型脑炎的病变是18.革囊胃指19-21是给病例分析是什么病A3、A4型题22-27B1型题28-35X型题36-40二、简答题（每题5分，共20分）1.毛细血管再生的过程2.AIDS病程的三个阶段3.Hodgkin淋巴瘤的组织学诊断依据4.膜性肾小球肾炎的病理变化三、论述题（每题10分，共40分）1.急性炎症过程中血流动力学改变2.风湿性心内膜炎的病理变化3.葡萄胎组织学特点及临床病理联系4.消化性溃疡的好发部位，病变特点，溃疡经久不愈和患者产生疼痛的原因*这么好的东西居然没人顶，真是服了*20071、卵巢组织发生分类，各举一例2、原发综合征病变特点及预后3、炎症介质？主要功能，并各举一例4、胃溃疡病的病理变化？5、二尖瓣狭窄病因、病理变化，血流动力学及心脏变化6、慢性肾小球肾炎及慢性肾盂肾炎多尿夜尿的机理7、血栓？下肢深静脉血栓的影响？8、慢性支气管炎、肺气肿与肺心病的病变及相互关系。
医学考博2019真题
Listening ：无Vocabulary ：Section A31. According to the Geneva ______no prisoners of war shall be subject to abuse.A. CustomsB. CongressesC. ConventionsD. Routines 32. Environmental officials insist that something be done to ______acid rain.A. curbB. sueC. detoxifyD. condemn33. It is impossible to say how it will take place, because it will happen______, and itwill not be a long process.A. spontaneouslyB. simultaneouslyC. principallyD. approximately34. Diabetes is one of the most______ and potentially dangerous disease in the world.A. crucialB. virulentC. colossalD. prevalent35. Rheumatologist advises that those with ongoing aches and pains first seek medicalhelp to ______the problem.A. affiliateB. alleviateC. aggravateD. accelerate36. How is it possible that such______ deception has come to take place right underour noses?A. obviousB. significantC. necessaryD. widespread37. Now a paper in Science argues that organic chemicals in the rock come mostly from______on earth rather than bacteria on Mars.A. configurationB. constitutionC. condemnationD. contamination38. Chronic high-dose intake of vitamin A has been shown to have ______effects onbones.A. adverseB. prevalentC. instantD. purposeful39. Generally, vaccine makers _____ the virus in fertilized chicken eggs in a processthat can take four to six months.A. penetrateB. designateC. generateD. exaggerate40. We are much quicker to respond, and we respond far too quickly by giving ______to our anger.A. ventB. impulseC. temperD. offenceSection B41. The patient's condition has worsened since last night.A. improvedB. returnedC. deterioratedD. changed42. Beijing Television-Station Transmitting Tower really looks magnificent at nightwhen it ’s lit up.A. decoratedB. illustratedC. illuminatedD. entertained43. Attempts to restrict parking in the city centre have further aggravated the problemof traffic congestion.A. amelioratedB. aggregatedC. deterioratedD. duplicated44. The applications of genetic engineering are abundant and choosing oneappropriate for this case can be rather difficult.A. sufficientB. plentifulC. adequateD. countable45. The defect occurs in the first eight weeks of pregnancy, though no one understandswhy.A. deficitB. deviationC. draw backD. discrepancy46. He has been on hormone alternate therapy for four years and looks fantastic.A. successorB. replacementC. surrogateD. choice47. It had over 2,000 apartment complexes, a great market, a large number ofindustrial workshops, an administrative center, a number of massive religious edifices,and a regular grid pattern of streets and buildings.A. ancientB. carefullyC. very largeD. carefully protected48. When patients spend extended periods in hospital, they tend to become overlydependent and lose interest in taking care of themselves.A. extremelyB. exclusivelyC. exactlyD. explicitly49. The anxious parent was vigilant over the injured child in spite of a full array ofemergency room of doctors and nurses.A. preoccupiedB. unwaryC. watchfulD. dozing50. The doctor vacillated so frequently on disease-preventiontechniques that hiscolleagues accused him of inconsistency.A. waveredB. instigatedC. experimentedD. reliedClozeWe spend a lot of time looking at the eyes of others for social 51 —it helpsus understand a person ’emotions, and make decisions about how to respond to them. We also know that adults avoid eye contact when anxious. But researchers have knownfar 52 about eye gazing patterns in children.According to new research by Kalina Michalska, assistant professor of psychologyat the University of California, Riverside, we now, know that anxious children tend toavoid making eye contact, and this has consequences for how they experience fear. The53 and less frequently they look at the eyes of others, the more likely they are to beafraid of them, even when there may be no reason to be. Her study, “Anxiety Sympand Children's Eye Gaze During Fear Leaming”w,as published in the journal TheJournal of Child Psychology and Psychiatry."Looking at someone ’s eyes helps us understand whether a person is feeling sad, angry, fearful, or surprised. As adults, we then make decisions about how to respondand what to do next. But, we know much less about eye patterns in children —so,understanding those patterns can help us learn more about the development of sociallearning, ”Michalska said.Michalska and the team of researchersshowed 82 children, 9 to 13 years old,images of two women ’s faces on a computer screen. The computer was equipped withan eye tracking device that allowed them to measure54 on the screen children werelooking, and for how long. The participants were originally shown each of the twowomen a total of four times. Next, one of the images was55 with a loud scream anda fearful expression, and the other one was not. At the end, children saw both facesagain without any sound or scream.The following three conclusions can be drawn from the study:1. All children spent more time looking at the eyes of a face that was paired withthe loud scream t han the face that was not paired with the scream, 56 they payattention to potential threats even in the absence of outward cues.2. Children who were more anxious avoided eye contact during all three phases of the experiment, for both kinds of faces. This had consequences for how afraid they wereof the faces.3. The more children avoided eye conta；cthe more afraid they were 57 the faces.The conclusions suggest that children spend more time looking at the eyes of aface when previously paired with something frightening suggesting they pay moreattention to potentially threatening information as a way to learn more about thesituation and plan what to do next.However, anxious children tend to avoid making eye contact, which leads togreater 58 experience. Even though avoiding eye contact may reduce anxiety59 , the study finds that — over time — children may be m i s s6i n0g_ o i m u p t ortantsocial information. This includes that a person may no longer be threatening or scary,and yet the child continues feeling fearful of that person.51. A. environment B. cues C. relations D. answers52. A. less B. more C. enough D. beyond53. A. longer B. more anxious C. shorter D. more54. A. where B. when C. how D. what55. A. followed B. recorded C. paired D. marked56. A. suggest B. suggesting C. suggests D. being suggested57. A. to B. of C.at D. about58. A. fear B. surprise C. sad D. angry59. A. in the long run B. for a long timeC. in the short timeD. in a long time60. A. with B. without C. of D. onReading ComprehensionPassage OneThe British psychoanalyst John Bowlby maintains that separation from the parentsduring the sensitive “attachment p”e riod from birth to three may scar a child ’s personality and predispose to emotional problems in later life.Some people have drawn the conclusion from Bowlby' s work that children shouldnot be subjected to day care before the age of three because of the parental separationit entails, and many people do believe this. It has been argued that an infant under threewho is cared for outside the home may suffer because of the separation from his parents. But there are also arguments against such a strong conclusion.But traditional societies are so different from modem societies that comparisonsbased on just one factor are hard to interpret. Firstly, anthropologists point out that theinsulated love affair between children and parents found in modem societies does notusually exist in traditional societies. For example, in some tribal societies, such as theNgoni, the father and mother of a child did not rear their infant alone —far from i Certainty, Bowlby ’s analysis raises the possibilities that early day care had delayedeffects. The possibility that such care might lead to, say, more mental illness or crime15 or 20 years later can only explored by the use of statistics. However, statisticalstudies of this kind have not yet been carried out, and even if they were, the resultswould certainly be complicated and controversial. Secondly, common sense tells us that day care would not be so widespread today if parents, care-takers found children hadproblems with it. Thirdly, in the last decade, t here have been a number of careful American studies of children in day care, and they have uniformly reported that care had a neutral or slightly positive effect on children ’s development.Whatever the long-term effects, parents sometimes find the immediate effectsdifficult to deal with. Children under three are likely to protest at leaving their parentsand show unhappiness. At the age of three or three and a half almost all children findthe transition to nursery eas，yand this is undoubtedly why more and more parents make use of child care at this time. The matter, then, is far from clear-cut, though experienceand available evidence indicate early care is reasonable for infants.61. According to the passage, the consequence of parental separation________.A. still needs more statistical studiesB. has been found negative is more seriousC. is obviousD. in modem times62. The author thinks that John Bowlby ’s concern___________.A. is relevant and justifiableB. is too strong to RelieveC. is utterly groundlessD. has something that deserve our attention63. What ’s the result of American studies of children in day care in the last decade?A. The children ’s unhappiness and protest was due to the day care the children received.B. The bad effects of parental separation were hard to deal with.C. The effect of day care was not necessarily negative on children ’s development.D. Early care was reasonable for babies since it ’p sracti c ed by so many peoplenowadays.64. According to the passage, which of the following is probably a reason forparents to send their children under three to day care?A. They don ’t know about day care ’s negative effect.B. They are too busy to care fortheir children.C. They want their children to be independent as early as possible.D. They want to facilitate their children to adapt to nursery at the age of about three.65. What ’s the author ’s attitude to people who have drawn the conclusion fromBowlby’s work that children should not be subjected to day care before the age ofthree?A. He supports most of their belief because Bowlby's proposition is well-grounded.B. He is sympathetic for them, for he thinks they have been misled by Bowlby.C. He doesn't totally agree with them, since the long-term effect of day care still needsfurther study.D. He doesn't quite understand them, as they are contradictory in themselves.Passage TwoBy the end of this century, the average world temperature is expected to increasebetween one and four degrees, with widespread effects on rainfall, sea levels and animalhabitats. But in the Arctic, where the effects of climate change are most intense, the risein temperature could be twice as much.Understanding how Arctic warming will affect the people, animals, plant andmarine life and economic activity in Canada’N sort h are important to the country's future, says Kent Moore, an atmospheric physicist at University of Toronto Mississaugawho is participating in a long-term, international study of the marine ecosystem alongthe Beaufort Sea, from Alaska to the Mackenzie delta.The study will add to our knowledge of everything from the extent of sea ice inthe region to how fish stocks will change to which areas could become targets for oiland gas exploration to the impact on the indigenous people who call this part of thecountry home.Moore, who has worked in the Arctic for more than 20 years, says his research hasalready found that thinning sea ice and changes in wind patterns are causing animportant change in the marine food chain: phytoplankton（淳游植物） is blooming two to three weeks earlier. Manyanimals time their annual migration to the Arctic forwhen food is plentiful, and have not adapted to the earlier bloom. " ' Animals' behaviorcan evolve over a long time, but these climate changes are happening in the space of adecade, r ather than hundreds of years, ”says Moore, " Animals can't change theirbehavior that quickly. ”A warmer Arctic is expected to have important effects on human activity in theregion, as the Northwest Passage becomes navigable during the summer, and resourceextraction becomes more feasible. Information gained from the study will helpgovernment, industry and communities make decisions about resource management,economic development and environmental protection.Moore says the study — which involves Canadian, American and Europeanresearchersand government agencies will also use a novel technology to gatheratmospheric data: remotely piloted drones. "The drones have the capability of a largeresearch aircraft，and they ’re easier to deploy, ” he says, showing the researchers to gather information on a more regular basis than they would be able to with pilotedaircraft.66. By the end of this century, according to the author, global warming will ______.A. start to bring about extreme weather events to humans and animalsB. increase the average world temperature by four degreesC. cause more damages to the whole world than expectedD. affect the Arctic more than any other parts of the earth67. To help understand the destructive mechanism of Arctic warming, as indicatedby the passage, the international study ______.A. is conducted with every single discipline of University of TorontoB. pioneers in pursuing the widespread effects of climate changeC. involves so many countries for different investigationsD. is intended to deal with various aspects in research68. When he ways, “Animals can ’t change their behavior that quickly, ”what doesMoore mean by that quickly?A. The migration of the animals to the Arctic.B. The widespread effects of global warming.C. The rate of the climate change in the Arctic.D. The phytoplankton within the marine ecosystem.69. According to the author, to carry out proper human activities in theArctic______.A. becomes more difficult than ever beforeB. is likely to build a novel economy in the regionC. will surely lower the average world temperatureD. needs the research-based supporting information70. With the drones deployed, as Moore predicts, the researchers will _______.A. involve more collaborating countries than they do nowB. get more data to be required for their researchC. use more novel technologies in researchD. conduct their research at a regular basisPassage ThreeHaving too much caffeine during pregnancy may impair baby ’s liver development and increase the risk of liver disease in adulthood, according to a study published in theJournal of Endocrinology. Pregnant rats given caffeine had offspring with lower birth weights, altered growth and stress hormonelevels and impaired liver development. Thestudy findings indicate that consumption of caffeine equivalent to 2-3 cups of coffee may alter stress and growth hormone levels in a manner that can impair growth and development, and increase the risk of liver disease in adulthood.Previous studies have indicated that prenatal caffeine intake of 300 mg/day ormore in women, which is approximately 2 to 3 cups coffee per day, can result in lower birth weights of their children. Animalstudies have further suggestedthat prenatalcaffeine consumption may have more detrimental long-term effects on liverdevelopment with an increased susceptibility to non-alcoholic fatty liver disease, adebilitating condition normally associated w ith obesity and diabetes. However, theunderlying link between prenatal caffeine exposure and impaired liver developmentremains poorly understood. A better understanding of how caffeine mediates theseeffects could help prevent these health issues in people in the future.In this study, Prof Hui Wang and colleagues at Wuhan University in China,investigated the effects of low (equivalent to 2-3 cups of coffee) and high dose(equivalent of 6-9 cups of coffee) caffeine, given to pregnant rats, on liver function andhormone levels of their offspring. Offspring exposed to prenatal caffeine had lower levels of the liver hormone, insulin likegrowth factor (IGF-1), and higher levels of thestress hormone, corticosteroid at birth. However, liver development after birth showed a compensatory 'catch up' phase, characterised by increased levels of IGF-1, which is important for growth.Dr. Yinxian Wen, study co-author, says, “Our results indicate that prenatal caffeine causes an excess of stress hormone activity in the mother, which inhibits IGF-1 activityfor liver development before birth. However, compensatory mechanisms do occur after birth to accelerate growth and restore normalliver function, as IGF-1 activity increasesand stress hormone signalling decreases. The increased risk of fatty liver disease causedby prenatal caffeine exposure is most likely a consequence of this enhanced,compensatory postnatal IGF-1 activity. ”These findings not only confirm that prenatal caffeine exposure leads to lowerbirth weight and impaired liver development before birth but also expand our currentunderstanding of the hormonal changes underlying these changes and suggest thepotential mechanism for increased risk of liver disease in the future. However, theseanimal findings need to be confirmed in humans.Dr. Wen comments, "Our work suggeststhat prenatal caffeine is not good for babies and although these findingsstill need to be confirmed in people, I wouldrecommend that women avoid caffeine during pregnancy."71. Which of the following is NOT the problem of baby rats of pregnant rats givencaffeine?A. Lower birth weight.B. Smaller stress.C. Liver development problem.D. Growth problem.72. If a pregnant woman takes 3 cups of coffee, what will probably happen?A. Her weight will get lower and lower.B. The weight of her baby will get lower and lower.C. She will suffer from non-alcoholic fatty liver disease in a long run.D. Her baby will be more vulnerable to obesity and diabetes because of liver problem.73. Which of following is not correct according to the passage?A. A better understanding of the relationship between caffeine and effects has beenachieved.B. 4-5 cups of coffee could be categorized as medium-dose intake.C. Liver development problem may be remedied after birth by increased growth factor.D. The study is mainly conducted on the rats instead of human.74. What is the relationship between stress hormone and liver development whentaking in prenatal caffeine?A. Lower stress hormone, lower birth weight before birth.B. Higher stress hormone, lower growth hormone before birth.C. Higher stress hormone, more accelerated growth of weight after birth.D. Lower stress hormone, less accelerated growth of liver after birth.75. What can be the best summary of the last paragraph?A. The research hasn ’t been done on humans so pregnant women can ignore the results.B. The compensatory mechanism for liver growth makes prenatal caffeine intake safe.C. Experts suggest pregnant women should still avoid caffeine.D. We have known enough about the hormone changes underlying the healthPassage FourThe bizarre antics of sleepwalkers have puzzled police, perplexed scientists, and fascinated writers for centuries. There is an endless supply of stories about sleepwalkers.Persons have been said to climb on steep roofs, solve mathematical problems, composemusic, walk through plate-glass windows, and commit murder in their sleepHow many of these stories have a basis in fact, and how many are pure fakery?No one knows, but if some of the most sensational stories should be taken with a barrelof salt, others are a matter of record.In Revere, Massachusetts, a hundred policemen combed a waterfrontneighborhood for a lost boy who left his home in his sleep and woke up five hours lateron a strange sofa in a strange living room, with no idea how he had got there.There is an early medical record of a somnambulist who wrote a novel in his sleep.And the great French writer V oltaire knew a sleepwalker who once got out of bed,dressed himself, made a polite bow, danced a minuet, and then undressed and went backto bed.At the University of Iowa, a student was reported to have the habit of getting upin the middle of the night and walking three-quarters of a mile to the Iowa River. He would take a swim and then go back tohis room to bed.The world's champion sleepwalker was supposed to have been an Indian, PanditRamrakha, who walked sixteen miles along a dangerous road without realizing that hehad left his bed. Second in line for the title is probably either a Vienna housewife or a British farmer. The woman did all her shopping on busy streets in her sleep. The farmer,in his sleep, visited a veterinarian miles away.The leading expert on sleep in America claims that he has never seen a sleepwalker.He is Dr. Nathaniel Kleitman, a physiologist at the University of Chicago. He is said toknow more about sleep than any other living man, and during the last thirty-five yearshad lost a lot of sleep watching people sleep. Says he, "Of course, I know that there are sleepwalkers becauseI have read about them in the newspapers. B ut none of mysleepers ever walked, and if I were to advertise for sleepwalkers for an experiment, Idoubt that I'd get many takers."Sleepwalking, nevertheless, is a scientific reality. Like hypnosis, it is one of thosedramatic, eerie, awe-inspiring phenomena that sometimes border on the fantastic. Itlends itself to controversy and misconceptions, what is certain about sleepwalking isthat it is a symptom of emotional disturbance, and that the only way to cure it is to remove the worries and anxieties that cause it. Doctors say that somnambulism is muchmore common than is generally supposed.Some have estimated that there are fourmillion somnambulists in the United States. Others set the figure even higher. Manysleepwalkers do not seek help and so are never put on record, which means that anaccurate count can never be made.The simplest explanation of sleepwalking is that it is the acting out of a vividdream. The dream usually comes from guilt, worry, nervousness, o r some otheremotional conflict. The classic sleepwalker is Shakespeare ’L asdy Macbeth. Hernightly wanderings were caused by her guilty conscience at having committed murder. Shakespeare said of her, “The eyes are open but their sense is shut. ”The age-old question is: Is the sleepwalker actually awake or asleep. Scientists have decided that he is about half-and-half. Like Lady Macbeth, he has weightyproblems on his mind. Dr. Zeida Teplitz, who made a ten-year study of the subject, says, “Some people stay awake all night worrying about t heir problems. The sleepwalker thrashes them out in his sleep. He is awake in the muscular area, partially asleep in the sensory area." In other words, a person can walk in his sleep, move around, and do other things, but he does not think about what he is doing.76. The second sentence in the second paragraph means that_________.A. no one knows, but certainly all the sleep walking stories have something incredibleB. the sleepwalking stories are like salt adding flavor to people ’s lifeC. sleepwalking stories that are most fantastic should be sorted out from ordinary storiesD. the most fantastic sleepwalking stories may be just fictions, yet there are stilltruthfully recorded stories77. ________was supposed to be the world's champion sleepwalker.A. The student habitually walked to the Iowa River and swam in his sleepB. The man danced a minuet in his sleepC. The man walker sixteen miles along a dangerous roadD. The boy walked five hours in his sleep78. Sleepwalking is the result of ______ according to the passage.A. emotional disorderB. a vivid dreamC. lack of sleep and great anxietyD. insanity79. Dr. Zeida Teplitz seemed to_________.A. agree that sleepwalking sometimes leads to dangerous actsB. conclude that sleepwalkers are awake in their sensory areaC. disagree with the belief that sleep walkers are immune to injuryD. think that sleepwalking can turn into madness80. The writer makes it obvious that_________.A. sleepwalkers are often awakened by dangersB. most sleepwalkers can find ways to avoid self-injuryC. it is important to find out the underlying cause of sleepwalkingD. sleepwalking is actually a kind of hypnosisPassage FiveBeyond the basic animal instincts to seek food and avoid pain, Freud identifiedtwo sources of psychic energy, which he called "drives ”: aggression and libido. The keto his theory is that these were unconscious drives, shaping our behavior without themediation of our waking minds; they surface, heavily disguised, only in our dreams.The work of the past half-century in psychology and neuroscience has been to downplaythe role of unconscious universal drives, focusing instead on rational processesinconscious life. But researchers have found evidence that Freud s drives really do exist,and they have their roots in the limbic system, a primitive part of the brain that operatesmostly below the horizon of consciousness.Now more commonly referred to as emotions, the modem suite of drives comprises five: rage, panic, separation distress,lust and a variation on libido sometimes called seeking.The seeking drive is proving a particularly fruitful subject for researchers.Although like the others it originates in the limbic system, it also involves parts of theforebrain, the seat of higher mental functions. In the 1980s, Jaak Panksepp, aneurobiologist at Bowling Green State University in Ohio, became interested in a placenear the cortex known as the ventraltegmental area, which in humans lies just abovethe hairline. When Panksepp stimulated the corresponding region in a mouse, theanimal would sniff the air and walk around, as though it were looking for something.Was it hungry? No. The mouse would walk right by a plate of food, or for that matterany other object Panksepp could think of. This brain tissue seemed to cause a generaldesire for something new. “What I was seeing, ” he says, “was the urge to do stuff.Panksepp called this seeking.To neuropsychologist Mark Solms of University College in London, that soundsvery much like libido. “Freud needed some sort of general, appetitive desire to seekpleasure in the world of objects, ” says Solms. "Panksepp discovered as a neuroscientist what Freud discovered psychologically. ” Solms studied the same region of the brain forhis work on dreams. Since the 1970s, neurologists have known that dreaming takesplace during a particular form of sleep known as REM — rapid eye movement — whichis associated with a primitive part of the brain known as the pons. Accordingly, they regarded dreaming as a low-level phenomenon of no great psychological interest. WhenSolms looked into it, though, it turned out that the key structure involved in dreaming was actually the ventral tegmental, the same structure that Panksepp had identified as the seat of the “”s e e m k i o n t g i o n. Dreams, it seemed, originate with the libid—o which is just what Freud had believed.Freud's psychological map may have been flawed in many ways, but it alsohappensto be the most coherent and, from the standpoint of individual experience,meaningful theory of the mind. “Freud should be placed in the same category as Darwin,who lived before the discovery of genes, ” says Panksepp. “Freud gave us a vision ofmental apparatus. We need to talk about it, develop it, test it. ” Perhaps it ’sof proving Freud wrong or right, but of finishing the job.。
2022年考博病理题套
95-考博病理试题31套本贴收到1朵鲜花95-考博病理试题31索引:1第二军医大病理学(硕士)2武汉大学医学院病理学考博试题3第四军医大学1996年招收攻读硕士硕士入学试题（病理学—1）4浙江大学医学院——病理学年博士硕士入学考试试题5国家医学考试中心病理学（博士全国统考题）6山东大学医学院—内分泌学博士硕士入学考试试题(多了一套内分泌试题,不改了)7北医考博病理试题8第四军医大学1995年博士入学考试病理学试题答题指南9第四军医大学1996年博士入学考试病理学试题10中山大学医学部博士入学考试病理学试题11中山大学医学部博士入学考试病理（专业基础）试题12中山大学医学部博士入学考试病理（专业基础）13浙江大学医学院博士入学病理试题14浙江大学医学院博士入学考试病理学试题15武汉大学医学部博士入学病理生理试题16天津医科大学博士入学病理试题17天津医科大学博士入学病理试题18上海第二医科大学博士入学考试病理学试题19华中科技大学同济医学院博士入学考试病理学（专业基础）试20华中科技大学同济医学院博士入学考试病理学（专业基础）试题21华中科技大学同济医学院博士入学考试病理学（专业基础）试题22华中科技大学同济医学院博士入学考试病理学（专业基础）试题23华中科技大学同济医学院1999年博士入学考试病理学（专业基础）试题24复旦大学医学院博士入学考试病理学试题25第四军医大学1997年博士硕士入学考试病理学试题（包括病理专业及其他专业）26 天医病理学硕士试题一.名词解释27 上海第二医科大学硕士入学考试病理试题（部分）名词解释30题28 上海交通大学考研病理试题29 复旦大学硕士硕士入学考试病理学试题30 北京大学医学部硕士硕士入学考试病理学试题31 重庆医科大学病理学（硕士）32 重庆医科大学病理学硕士入学试题试题:1第二军医大病理学(硕士)一、名词解释（30个共30分）化生，炎性假瘤，变质，变性，黏液样变，虎斑心，心衰细胞，槟榔肝，糜烂，肉芽组织，瘢痕组织，肺褐色硬化，伤寒细胞，绒毛心，恶性溃疡，桥接坏死，二、问答题：（一）1 良恶性肿瘤旳区别。
南开大学病理生理学2019年考博真题试卷
医学考博真题试卷
攻读博士学位研究生入学考试试卷
南开大学医学院
2019年攻读博士学位研究生入学考试试题
考试科目：病理生理学
注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
一、名词解释
代谢性碱中毒
肝性脑病
低钾血症
二、简答题
1高钾血症酸碱代谢失衡的类型及心肌电生理特点
2MODS的组织和代谢变化
3肝纤维化的发病机制
4肺换气功能障碍的类型和机制
5全身缺氧的代偿和损伤变化
三、论述题
1休克器官功能障碍的细胞机制10分
2细胞功能ห้องสมุดไป่ตู้碍的方式，心血管疾病和肿瘤试述15分
3缺血再灌注钙超载的作用机制15分
4体液因素在损伤中的的作用方式简述，外泌体在衰老和肿瘤中的作用方式，机制15分
北京中医药大学病理生理学2019年考博真题试卷
1受体Байду номын сангаас常的类型
2什么是阴离子间隙？临床意义什么？
3DIC出现出血的原因
4肝功能受损时候血糖变化以及机制
5失血性休克时候缺氧的类型及血氧指标的变化
三、问答题（每题10分）
1左心衰时，最早出现的功能变化是什么？其临床表现的程度及机制。
2肺通气血流比例失调时影响因素及机制。
3肾脏“矫枉过正”学说。
北京中医药大学
医学考博真题试卷
攻读博士学位研究生入学考试试卷
北京中医药大学
2019年攻读博士学位研究生入学考试试题
考试科目：病理生理学
注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
1、名词解释
氧自由基
细胞信号转导
病理生理过程
发绀
凋亡蛋白酶
胰岛素抵抗
反常性碱性尿
发热
热休克蛋白
泵--漏机制
4休克时酸中毒类型、机制及影响。
5急性低钾血症时、急性高钾血症时导致无力的原因？
6举例说明因果交替的规律。
2019全国博士考试病生真题-10页文档资料
2009年全国医学博士入学考试专业基础（病理生理学）一、选择题（1分X40）A型30道，B型5道，X型5道二、简答题（5分X4）1、左心衰竭出现夜间阵发性呼吸困难的机制。
2、ARDS出现I型呼吸衰竭的机制。
3、肾性贫血的机制。
4、产科意外导致DIC的机制。
三、论述题（10分X4）1、一位流感病人体温39.7C，试述其发热的基本机制。
2、缺氧的类型以及各型的血氧指标的变化。
3、病例分析题，考水、电解质、酸解平衡紊乱的。
4、假神经递质在肝性脑病发病中的作用。
09病生1. 恶性肿瘤发生过程中有哪些细胞调控障碍？原因？2. 细胞信号转导异常的环节有哪些？3. 低钾血症对机体的影响？4. 自由基在缺血-再灌损伤中的作用？5. 血液性缺氧的原因及血气变化？6. 何谓抑癌基因？举例说明其失活机制。
7. 肝功能异常时血氨升高的原因？8. 原发性高血压中有哪些离子转运障碍？有什么结果？9. DIC引起休克的机制？10. 患者车祸后，表情淡漠，面色青灰，血压70/50mmHg，脉快，补液后尿量≤30ml/24h。
该患者处于哪一时期？发生机理？08病生1.哪些因素可以引起细胞信号转导异常？2.何谓水中毒？产生机制与对机体的影响？3.呼酸的发生原因基对机体的影响？4.低张性缺氧的原因血氧变化特点?5.DIC的主要临床表现？产生机制？6.钙超载在心肌缺血-再灌损伤中的作用？7.主要细胞癌基因的致癌机制?8.心衰使兴奋-收缩偶偶联障碍机制?9.女，65岁，支气管哮喘15年，近来呼吸困难加重，且出现嗜睡等表现，血气PaCO2 75mmHg ，PaO2 50mmHg。
试述患者发生上述临床表现的机制？10.男，22岁，因胆囊炎滴注庆大霉素4周后出现少尿，恶心，呕吐等症状，PH7.25 BE-15mm ol/l PaCO2 28mmHg, SB 18 mmHg, K 6.8 mmol/l ,BUN 25.8 mmol/l.试述该患者有哪些病理生理过程，是怎样发生的？南方医科大学2019年病理生理学（博士）一、简答题：4题×5分_1.简述gaba在肝性脑病中的作用2.为什么部分肺泡通气/血流比例下降只导致低氧血症，而不会导致paco2升高？:3.简述dic时出血的机制TY M6P"_Ep4.肾性高血压的发病机制二、论述题：1.一患者，血压波动于160/100近十年，近期发生左心衰竭，，请分析其发病机制（15分）2.试述休克i 期微循环变化的特点、机制和代偿意义（10分）3.一肺心病患者，入院呈昏睡状态，查：ph 7.26，paco2 65.5, hco3－30,cl－92, na＋145,试分析患者为何种酸碱失衡及电解质紊乱？根据是什么？并分析期昏睡的机制？（15分）2009年病理生理题目：简答题：1．肾性贫血发病机制2．产科意外导致DIC机制3．阵发性夜间呼吸困难的发病机制4．ARDS发生1型呼吸衰竭的机制问答题：1．感染发热的机制2．缺氧的类型以及血液氧指标的变化3．病例分析（酮症酸中毒），写出该病例的水、电介质、酸碱平衡混乱的类型及机制4．假性神经递质在肝性脑病发病中的作用2009年中山大学博士入学考试病理生理学专业基础真题！一、名词解释（5分一个）1、paroxysmal nocturnal dyspnea2、SIRS3、stress disease4、renal tubular acidosis二简答题（20分一个）1、DIC引起出血的发病机制。
病理生理学考博试题及答案
病理生理学考博试题及答案病理生理学是研究生物体在疾病状态下的生理变化及其机制的科学。
本试题旨在考察考生对病理生理学基本概念、原理和机制的理解与应用能力。
一、选择题（每题2分，共20分）1. 病理生理学主要研究的是：A. 疾病的预防B. 疾病的治疗C. 疾病的病因D. 疾病状态下的生理变化2. 细胞凋亡是：A. 一种病理性死亡B. 一种生理性死亡C. 细胞分裂D. 细胞生长3. 炎症反应的目的是：A. 清除损伤因子B. 促进细胞增殖C. 抑制细胞凋亡D. 促进组织修复4. 以下哪项不是细胞应激反应的类型？A. 热休克反应B. 氧化应激反应C. 免疫应激反应D. 营养应激反应5. 细胞程序性死亡的调控机制不包括：A. 基因调控B. 信号传导C. 细胞代谢D. 细胞外基质答案：1. D2. B3. A4. C5. C二、简答题（每题10分，共30分）6. 简述病理性钙化的特点及其对机体的影响。
7. 描述缺氧对细胞代谢的影响。
8. 解释什么是细胞信号转导异常，以及它在疾病中的作用。
答案：6. 病理性钙化是指在非骨骼组织中异常沉积的钙盐，其特点包括钙化部位的非特异性、钙化过程的病理性以及可能伴随的组织损伤。
对机体的影响包括影响组织功能、引起疼痛和功能障碍等。
7. 缺氧时，细胞内ATP生成减少，导致细胞代谢活动受限。
细胞可能通过糖酵解途径产生能量，但效率较低。
长期缺氧可导致细胞损伤甚至死亡。
8. 细胞信号转导异常是指细胞内信号传递过程中的某个环节出现问题，导致细胞功能失调。
这可能涉及到信号分子的异常表达、受体功能的改变或信号传导途径的障碍等。
在疾病中，信号转导异常可能导致细胞增殖失控、细胞凋亡受阻等病理变化。
三、论述题（每题25分，共50分）9. 论述细胞凋亡与坏死的区别及其在疾病中的意义。
10. 阐述肿瘤微环境对肿瘤发展的影响。
答案：9. 细胞凋亡是一种有序的、程序化的细胞死亡过程，通常不引起炎症反应，而坏死是一种非程序化的、由外界因素引起的细胞死亡，常伴随炎症反应。
北医、同济、中山、中国医科大学、哈医大、北京协和医院、武汉大学病理生理学考博真题合集
2012北医专业基础—病理生理学（原题）一、名词解释（30分）1.pathogenesis process2.hypervolemic hyponatremia3.anion gap4.histogenous hypoxia5.hyperthermia6.oxygen paradox7.shock8.restrictive hypoventilation9.pulmonary encephalopathy10.false neurotransmitter二、简答（70分）1.血管内外液体交换异常引起水肿的机制2.代谢性酸中毒的类型及发生原因3.热休克蛋白的定义及其功能4.DIC的分期及各期的特点5.什么是无复流现象，其发生机制如何6.呼吸困难在哪种类型的心衰最常见？该型心衰引起的呼吸困难与那些因素有关？7.急性肾衰少尿期最严重的并发症是什么？其发生机制是？2012年同济大学病理生理学真题（回忆）一、名词解释：1.脑死亡2.MODS3.ARDS4.肾功能不全5.呼吸衰竭6.应激性溃疡7.充血性心力衰竭8.PH反常9.内生致热源10.热休克蛋白11.心室重构12.微血管性溶血性贫血13.激素不敏感14.等渗性脱水二、选择题三、问答题1.急性全身性DIC为何会引起广泛出血和休克，其机制如何？2.心力衰竭者腹水的发生机制（是一个案例分析，大概是这个意思）3.风湿性心脏病二尖瓣狭窄的病理生理变化4.简述急性肾炎发生的机制5.肝性脑病时假神经递质有哪些？它们是如何引起肝性脑病的？2012中山大学病理生理（A）：1.名词解释：（都是英文）缺血再灌注损失凋亡心源性休克功能性分流2.论述题1）急性低钾血症和急性高钾血症引起肌无力的机制区别2）DIC的发病机制3）从细胞增殖和凋亡方面论述肿瘤的分子机制4）什么是SIRS、CARS、MARS？它们和多器官功能衰竭的关系？交大病生简答：内毒素引起MODS的机制。
DIC晚期患者易发生出血倾向的机制。
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医学考博真题试卷
兰州大学
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2019 年攻读博士学位研究生入学考试试题
考试科目：病理学和病理生理学 注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
一、选择题（25 个单选，5 个多选）
二、名词解释 5 个 1. nanplasia tumor 2. 肉芽肿性炎 3. 桥接坏死 4. 肺褐色硬变 5. 全身适应综合征
三、简答题 4 个 1. 肺结核的基本病变特征，形成条件 2. 胃溃疡的病理学特点，疼痛的原理 3. 固缩肾由哪些疾动的机制
四、论述题 2 个 1. 发热的分期及热代谢特点 2. 分子病理学的含义。与传统组织病理学的区别
英语 作文是批判性思维 翻译是 copd
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