细胞凋亡

BBaakk BBaaxx
C
C
Bid
Bax
CARD
C CC C
Apaf1
Cathepsin
Casp 12
28S
C
C
Bcl-2
Diablo
Diablo C CC
Bax
eIF2
CC
Bcl-2
EndoG
C CC
PTP
Bax
CC C
EndoG AIF
Diablco IAP
EndoG Diablo
AIF
Casp 3
CC
C C
C CC
C
C
CCC
C
CC
C
Diablo EndoG
AIF
Diablco IAP
CC C
CARD
EndoG
EndoG AIF
Apaf1
FADD FADD
RAID
FADD FADD
DDDD DD
DISC Cas
Cas
10
8
CARDCasp 2
CARD
Bcl-2
C
BAP31 p20
Bid
Casp10
Caspase 3 Substrates
Ire-1 PERK
Bax Bax
RYR
Bid Apaf1
CARD
AAAAA AAAAA
ChK2 ATM
CARD
Apaf1 C
C
Casp 3
Caspase 3 Substrates
Genotoxic stress
Mitochondria and ER in apoptosis
m-Calpain
CC
C
C C C CC
Bcl-XL
C
C
C CC
Casp 3
Caspase 3 Substrates
IR
FADD FADD
RAID
FAS-L Signaling in apoptosis
FAFSAF-SLA-SL-L
FAS-L
FAS-L
DD DED
DDDD DD
DDDD DD
DDDD DD
FADD FADD FADD FADD
FADD FADD
DNA damage-induced apoptosis
p53
Bax
Bcl-2
Bid
CC C
C CC
CARD
Pin 1
p53
p53 S20 S15
PARC
MDM 2
FAS
AAAAA
Puma AAAAA
Bid
AAAAA
CARD
NOXA
AAAAA
Bax
AAAAA
Apaf1
AAAAA
Chk2
ATM
Apaf1
Casp10
Casp 8
Cas FLIP 8
BAP31 p20
Caspase 3 Substrates
TNF R1 Signaling in apoptosis
R1
R1 R1
TTNTNFNFF
SODD
TNF
R1 R1 R1
Death Domain
SODD
SODD SODD
DD
DD DD
AIF EndoG
RAID
FADD FADD
EndoG
AIF EndoG
CC
C CΒιβλιοθήκη Baidu
C CC
C
C
CCC
C
CC
C
CARDCasp 2
CARD
DISC Cas 10
Bcl-2
C
Bid
Casp 9 Apaf1 Apaf1 Casp 9
EndoG
C
C
CARD
Diablo
C EndoG
AIF
CARD
Diablco IAP
Casp 3 Casp 6 Casp 7
Casp 8
Casp 3 Casp 6 Casp 7
FLIP
Caspase Substrates
Role of p53 in apoptosis
Bax
O-, OH-, NO-
C
MDM 2
p53 S15
S20 PARC
Pin 1
p53
FAS
AAAAA
Puma AAAAA
NOXA
AAAAA
Bax
AAAAA