大学生与高眼压者眼压与角膜厚度、角膜曲率关系

Advances in Clinical Medicine 临床医学进展, 2017, 7(2), 113-122

Published Online June 2017 in Hans. /journal/acm

https:///10.12677/acm.2017.72019

Correlation between Central Intraocular

Pressure and Corneal Thickness, Corneal

Curvature in College Students and High

Intraocular Pressure Group

Youliang Wang1, Junshu Wu2*, Qiaowei Wu1, Junxian Wen1, Jiasong Chen1, Zaoxuan Wu1

1Guangzhou Medical University, Guangzhou Guangdong

2Department of Ophthalmology, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou

Guangdong

Received: May 22nd, 2017; accepted: Jun. 17th, 2017; published: Jun. 20th, 2017

Abstract

Objective: to study the correlation between intraocular pressure (IOP) and central corneal thick-ness (CCT), corneal curvature in normal intraocular pressure group of college students and high intraocular pressure group. Method: use non-contact tonometer (NCT), a ultrasound pachymeter UP-1000 and automatic optometry instrument to measure IOP, CCT and corneal curvature of col-lege students with normal IOP in Guangzhou Medical University (31 cases) and outpatients with high IOP of the Second Affiliated Hospital of Guangzhou Medical University (22 cases). Results: ag-gregately analysing, there is no significant correlation between IOP and CCT (Pearson, r = 0.129, P = 0.356) as well as between IOP and corneal curvature (Pearson r = 0.090, P = 0.541); separately analysing, the IOP and CCT of two groups had no significant correlation respectively (Pearson r =

0.153, P = 0.410, Pearson r = 0.048, P = 0.832); the IOP and corneal curvature of two groups had no

significant correlation respectively (Pearson r = 0.194, P = 0.323 Pearson, r = −0.01, P = 0.964).

Conclusions: there is no correlation between the IOP and corneal thickness, corneal curvature in normal intraocular pressure group of college students and high intraocular pressure group.

Keywords

Corneal Thickness, Corneal Curvature, High Intraocular Pressure, College Students

大学生与高眼压者眼压与角膜厚度、角膜曲率关系

王游梁1，吴君舒2*，伍巧微1，文俊贤1，陈家松1，吴灶璇1

*通讯作者。

文章引用: 王游梁, 吴君舒, 伍巧微, 文俊贤, 陈家松, 吴灶璇. 大学生与高眼压者眼压与角膜厚度、角膜曲率关系[J].

王游梁等

1广州医科大学，广东广州

2广州医科大学附属第二医院眼科，广东广州

收稿日期：2017年5月22日；录用日期：2017年6月17日；发布日期：2017年6月20日

摘要

目的：研究大学生群体以及高眼压群体的中央角膜厚度(CCT)与眼压测量值(IOP)以及角膜曲率的相关性。

方法：应用非接触眼压计(NCT)、A超角膜测厚仪UP-1000和验光仪分别测量广州医科大学在校大学生(31例)和广州医科大学附属第二医院眼科门诊高眼压就诊者(22例)的眼压值、角膜厚度和角膜曲率，观察眼压与各参数之间的关系。结果：将正常眼压组和高眼压组数据合并分析，眼压与角膜厚度不相关(Pearson r = 0.129, P = 0.356)；分别分析，两组各自的眼压与角膜厚度也不相关(Pearson r = 0.153, P = 0.410, Pearson r = 0.048, P = 0.832)。将正常眼压组和高眼压组数据合并分析，眼压与角膜曲率不相关

(Pearson r = 0.090, P = 0.541)。分别分析，两组各自的眼压与角膜曲率也不相关(Pearson r = 0.194, P = 0.323, Pearson r = −0.01, P = 0.964)。结论：正常眼压组(大学生群体)与高眼压组的眼压与中央角膜厚度以及角膜曲率不相关。

关键词

角膜厚度，角膜曲率，高眼压，大学生

Copyright © 2017 by authors and Hans Publishers Inc.

This work is licensed under the Creative Commons Attribution International License (CC BY).

/licenses/by/4.0/

1. 引言

压平眼压计测量眼内压是通过压平眼角膜来实现的，而角膜厚度和角膜曲率是角膜形态的两个重要决定因素，故理论上可能会影响眼压的压平过程，从而对测出来的眼压值有影响。目前对角膜厚度与眼压关系的研究多集中在平均年龄40岁左右的人群，也有以未成年人为专门研究对象的[1]，而针对大学生群体的相关研究不多。另外，角膜曲率与眼压的关系目前还没有定论。我们检测了正常眼压的大学生人群和医院眼科门诊的高眼压病人的眼压、角膜厚度和角膜曲率，旨在探讨两组人群中眼压与中央角膜厚度和角膜曲率的关系。

2. 资料与方法

2.1. 研究对象

本研究选取的研究对象是2015年11月至2016年11月在广州医科大学附属第二医院眼科门诊就诊的高眼压者和广州医科大学在校大学生，共52例(52只眼)，其中高眼压者22例、正常眼压31例。男性27例，女性26例，年龄17~64岁，正常眼压者平均年龄[20.00 (19.00, 20.00)]岁，高眼压者平均年龄[23.50

(19.75, 39.00)]岁。