【医学免疫学】免疫学概论(英文版)
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Medical Immunology
Introduction to Immunology
What is Medical Immunology?
Immunology
is the study of the ways in 胸腺 which the body defends itself from infectious agents and other foreign substances in its environment.
the physical, chemical and physiological characteristics of the components of the immune system.
Immunology
Basic Immunology
Moleclules: Ag, Ig, MHC… Immune cells: T,B, APC, NK… Immune response:
What disease does this man have?
Progression of Smallpox
天花病毒 (Pox virus)
Day 3
Day 5
Day 7
祖国医学：扶正祛邪、阴阳理论
人痘苗 (南宋时期)
中国古代有关痘苗文献
Edward Jenner (1749-1823)
Innate Adaptive (Cellular, Humoral)
Clinical Immunology
Hypersensitivity (Allergy) Immune tolerance Immunodeficiency Tumor immunity …
学科特点
1、理论深奥、抽象； 2、名词概念的英文缩略语多； 3、分子及基因水平的内容多； 4、前后知识联系特别紧密； 5、是当今生命科学最重要的前沿学科之一。
淋巴结 脾脏
骨髓
Immune system
Immunology
- The Basis of Medicine
the physiological functioning of the immune system in states of both health and disease;
malfunctions of the immune system in immunological disorders;
Elsevier Saunders 2012 Janeway C A, et al. Immunobiology. 7th ed.
Garland Science Publishing 2007
self nonself
immune tolerance immune response
Contents:
Vaccination (1796)
最后一例天花患者 阿里•毛•马林
1979年10月26日 世界卫生组织宣布消灭天花
《备急千
金药方》 （孙思邈， 唐朝581682）；
《肘后备急 方》（葛洪， 东晋283363）
Cao X. Immunology in China: the past, present and future. Nat Immunol. 2008;9(4):339-42
References
医学免疫学，金伯泉主编，人民卫生出版社，第5版 Abbas A K, et al. Basic Immunoloy. 3rd ed.
Elsevier Saunders 2008 Abbas A K, et al. Cellular and Molecular Immunology.7th ed.
benefits; damaging effects
5.Immunology: study the structure of immune system and its functions.
Brief History of Immunology
1. Empirical Immunology
2. Scientific Immunology
3.Immune system: immune tissues and organs, immune cells, immune molecules
4.Immune response: is the response made by the host to defend itself against the introduction of foreign substances.
Introduction
Concept of Immunity Brief History of Immunology Immunological Functions Immune Response of the Immune System Immunopathology
3. Modern Immunology
1）The genetic principle of diversity and specificity of antibodies 2）Gene cloning of T cell receptor 3）Immunogenetics and MHC restriction 4）Cytokines and receptors 5）Signal transduction
(to recognize and eliminate foreign substances)
2.Substances: microorganisms (viruses, bacteria etc) and their products, foods, chemicals, pollen, tumor cells, etc.
Introduction
Immunity
1.Immunity: refers to all mechanisms used by the body as protection against environmental substances that are foreign to the body.
Introduction to Immunology
What is Medical Immunology?
Immunology
is the study of the ways in 胸腺 which the body defends itself from infectious agents and other foreign substances in its environment.
the physical, chemical and physiological characteristics of the components of the immune system.
Immunology
Basic Immunology
Moleclules: Ag, Ig, MHC… Immune cells: T,B, APC, NK… Immune response:
What disease does this man have?
Progression of Smallpox
天花病毒 (Pox virus)
Day 3
Day 5
Day 7
祖国医学：扶正祛邪、阴阳理论
人痘苗 (南宋时期)
中国古代有关痘苗文献
Edward Jenner (1749-1823)
Innate Adaptive (Cellular, Humoral)
Clinical Immunology
Hypersensitivity (Allergy) Immune tolerance Immunodeficiency Tumor immunity …
学科特点
1、理论深奥、抽象； 2、名词概念的英文缩略语多； 3、分子及基因水平的内容多； 4、前后知识联系特别紧密； 5、是当今生命科学最重要的前沿学科之一。
淋巴结 脾脏
骨髓
Immune system
Immunology
- The Basis of Medicine
the physiological functioning of the immune system in states of both health and disease;
malfunctions of the immune system in immunological disorders;
Elsevier Saunders 2012 Janeway C A, et al. Immunobiology. 7th ed.
Garland Science Publishing 2007
self nonself
immune tolerance immune response
Contents:
Vaccination (1796)
最后一例天花患者 阿里•毛•马林
1979年10月26日 世界卫生组织宣布消灭天花
《备急千
金药方》 （孙思邈， 唐朝581682）；
《肘后备急 方》（葛洪， 东晋283363）
Cao X. Immunology in China: the past, present and future. Nat Immunol. 2008;9(4):339-42
References
医学免疫学，金伯泉主编，人民卫生出版社，第5版 Abbas A K, et al. Basic Immunoloy. 3rd ed.
Elsevier Saunders 2008 Abbas A K, et al. Cellular and Molecular Immunology.7th ed.
benefits; damaging effects
5.Immunology: study the structure of immune system and its functions.
Brief History of Immunology
1. Empirical Immunology
2. Scientific Immunology
3.Immune system: immune tissues and organs, immune cells, immune molecules
4.Immune response: is the response made by the host to defend itself against the introduction of foreign substances.
Introduction
Concept of Immunity Brief History of Immunology Immunological Functions Immune Response of the Immune System Immunopathology
3. Modern Immunology
1）The genetic principle of diversity and specificity of antibodies 2）Gene cloning of T cell receptor 3）Immunogenetics and MHC restriction 4）Cytokines and receptors 5）Signal transduction
(to recognize and eliminate foreign substances)
2.Substances: microorganisms (viruses, bacteria etc) and their products, foods, chemicals, pollen, tumor cells, etc.
Introduction
Immunity
1.Immunity: refers to all mechanisms used by the body as protection against environmental substances that are foreign to the body.