最新肠道菌群与代谢疾病ppt课件

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Eamonn M.M. Quigley. Do patients with functional gastrointestinal disorders have an altered gut flora? Ther Adv Gastroenterol (2009) 2(Suppl 1) S23–S30.
好细菌和坏细菌
菌群是健康的核心
Nathalie M. Delzenne, et al., Targeting gut microbiota in obesity: effects of prebiotics and probiotics. Nat. Rev. Endocrinol. 7, 639–646 (2011).
一篇值得关注的综述
Nature reviews. Microbiology 最新的影响因子为22.490 (2013)
人菌共生
Kristina Harris,et al., Is the GutMicrobiota a New Factor Contributing to Obesity and ItsMetabolic Disorders? Journal of Obesity, Volume 2012, p 1-14.
影响肠道菌群的因素
肠-脑轴/脑-肠轴
• Germ Free (GF) Mice Display Increased Motor Activity and Reduced Anxiety-Like Behavior.
• results suggest that the microbial colonization process initiates signaling mechanisms that affect neuronal circuits involved in motor control and anxiety behavior.
肠-脑轴的概念
Augusto J. Montiel-Castro, et al., The microbiota–gut–rainaxis: neurobehavioral correlates, healthand sociality. Front in Integ Neuro. Oct 2013 | Vol7 | Article 70 | 1-16.
Q. AZIZ, et al., Gut microbiota and gastrointestinal health: current concepts and future directions. Neurogastroenterol Motil (2013) 25, 4–15.
菌群影响神经功能
肠道菌群对人生理的影响
肠道菌群-代谢产物-功能
Jeremy K. Nicholson et al., Host-Gut Microbiota Metabolic. Science 336, 1262-1267, 2012.
影响肠道菌群的因素
Nathalie M. Delzenne & Patrice D. Cani, Interaction Between Obesity and the Gut Microbiota: Relevance in Nutrition. Annu. Rev. Nutr. 2011. 31:15–31.
菌群紊乱致焦虑和抑郁
Jane A. Foster and Karen-Anne McVey Neufeld, Gut–brain axis: how the microbiome influences anxiety and depression. Trends in Neurosciences, May 2013, Vol. 36, No. 5, P 305312
脑-肠轴/肠-脑轴:迷走神经
Sue Grenham,et al., Brain–gut–microbe communication in health and disease. Frontiers in Physio. Gastroint Sci Dec 2011 Vol 2 p 1-15.
肠脑轴/脑肠轴
精神活动影响肠道菌群
exposure to psychological stress results in a significant reduction in the production of mucin and a decreased presence of acidic mucopolysaccharides on the mucosal surface.
Jason A. Hawrelak & Stephen P. Myers, The Causes of Intestinal Dysbiosis: A Review. Altern Med Rev 2004;9(2):180-197.
应激/压力引起胃肠疾病
P.C. KONTUREK, et al., STRESS AND THE GUT: PATHOPHYSIOLOGY, CLINICAL CONSEQUENCES, DIAGNOSTIC APPROACH AND TREATMENT OPTIONS. J PHYSIO & PHARM 2011, 62, 6, 591-599.
人肠道菌群种类和数量
EAMONN M. M. QUIGLEY and RODRIGO QUERA, Small Intestinal Bacterial Overgrowth: Roles of Antibiotics, Prebiotics, and Probiotics. GASTROENTEROLOGY 2006;130:S78–S90
肠道菌群与代谢疾病ppt课 件
目录பைடு நூலகம்
• 肠道菌群与健康和疾病概述 • 肠-脑轴 • 肠-肝轴 • 肠道菌群与代谢性疾病:肥胖、糖尿病 • 肠道菌群与肠病 • 肠道菌群与免疫 • 肠道菌群与其它疾病 • 革命带来的挑战和机遇
悄悄发生的革命
INNA SEKIROV, et al., Gut Microbiota in Health and Disease. Physiol Rev 90: 859–904, 2010;
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