河南9万例高危人群上消化道癌内镜筛查及早诊早治分析

World Journal of Cancer Research 世界肿瘤研究, 2016, 6(1), 1-7

Published Online January 2016 in Hans. /journal/wjcr /10.12677/wjcr.2016.61001

文章引用: 陆建邦, 王福让, 张亚冰, 王振海, 党可军, 马文浩, 秦思豫, 王宏伟, 孙喜斌. 河南9万例高危人群上消

Analysis of Results of Endoscopic Screening and Early Diagnosis and Treatment of Upper Digestive Tract Carcinoma More than 9 Million High-Risk Groups in Henan

Jianbang Lu 1*, Furang Wang 1, Yabing Zhang 2, Zhenhai Wang 3, Kejun Dang 4, Wenhao Ma 5, Siyu Qin 6, Hongwei Wang 7, Xibin Sun 1

1

Cancer Prevention and Control Office of Henan Province, Cancer Center of Henan Province, Zhengzhou Henan 2Medical Science Research Institute of Henan Province, Zhengzhou Henan 3

Linzhou Institute of Esophageal Cancer, Linzhou Henan 4

Jiyuan Cancer Hospital, Jiyuan Henan 5

Huixian People’s Hospital, Huixian Henan 6

Yanshi People’s Hospital, Yanshi Henan 7

Neixiang CDC, Neixiang County Henan

Received: Jan. 7th , 2016; accepted: Jan. 21st , 2016; published: Jan. 29th

, 2016

Copyright © 2016 by authors and Hans Publishers Inc.

This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/

Abstract

Objective: To study the process and results of endoscopic screening and early diagnosis and treatment for the cancer of upper digestive tract in high-incidence areas in Henan. Methods: 12 high-incidence cities and counties of upper gastrointestinal carcinoma in Henan province were in-cluded in this study. People aged 40-69 were set to the target population. Except contraindications for endoscopy, in accordance with the national technical scheme of early cancer diagnosis and treatment, endoscopic screening and histologic diagnosis for human esophagus, cardia and gaster of the target people were carried out. Results: During the 5-year period, more than 90,000 cases had a total sieve check, and in the 89,495 cases which entered the analysis, various precancerous in anatomy parts esophagus, cardia and gaster were found: 26,199 subjects (29.27%) in esopha-gus, 23,337 subjects (26.08%) in cardia and 3248 subjects (5.20%) in gaster respectively. A total of 2095 cases were found to have cancers (2.34%), followed by anatomy parts for 1.38%, and 0.73% and 0.33% respectively, among them 1706 cases had early stage with an early diagnosis rate was 81.72%. More than 3000 cases have been followed-up screening in near future, and we made a brief report on the 5-year treatment in Linzhou. Conclusion: The results of this study

*

通讯作者。

陆建邦等

demonstrate that endoscopic screening and early diagnosis and treatment for the target popula-tion aged at 40 - 69 is feasible in high-incidence areas of upper digestive tract carcinoma. We could intervene various types of precancerous lesions and have minimally invasive treatments to cancer developing in the early stages, which have positively effects on the prevention and treatment of upper digestive tract cancer and reducing mortality.

Keywords

Esophagus Carcinoma, Carcinoma of the Gastric Cardia, Gastric Cancer, High-Incidence Area,

Endoscopic Screening, Pathological Diagnosis, Early Diagnosis and Early Treatment

河南9万例高危人群上消化道癌内镜筛查及早

诊早治分析

陆建邦1*，王福让1，张亚冰2，王振海3，党可军4，马文浩5，秦思豫6，王宏伟7，孙喜斌1

1河南省肿瘤防治研究办公室，河南省癌症中心，河南郑州

2河南省医学科学研究院，河南郑州

3林州市食道癌研究所，河南林州

4济源市肿瘤医院，河南济源

5辉县市人民医院，河南辉县

6偃师市人民医院，河南偃师

7内乡县疾控中心，河南内乡县

收稿日期：2016年1月7日；录用日期：2016年1月21日；发布日期：2016年1月29日

摘要

目的：探讨在河南上消化道癌高发地区开展内镜筛查和早诊早治项目的过程和结果。方法：选择河南上消化道癌高发地区的12个市县，将40~69岁设定为目标人群。除外胃镜检查禁忌症者，按照国家《癌症早诊早治技术方案》，对筛查对象的食管、贲门、胃进行内镜检查并以组织学诊断进行评价。结果：5年来共筛查9万多例，在进入分析的89,495例中，发现各类癌前病变以解剖部位食管、贲门、胃来分，依次为26,199例(29.27%)、23,337例(26.08%)和3248例(5.20%)；共检出上消化道癌病例2095例，检出率2.34%，其中，食管1.38%，贲门0.73%，胃0.33%。早期病例1706例，占81.72%。对3000多例进行了近期随访筛查，对林州5年治疗情况做了简要报告。结论：在上消化道癌高发地区，对40~69岁高危人群开展内镜筛查和实施早诊早治是可行的，对各类癌前病变进行干预并对各类早期阶段癌变开展微创治疗，将会对防治上消化道癌，降低死亡率起到积极地作用。

关键词

食管癌，贲门癌，胃癌，高发区，内镜筛查，病理诊断，早诊早治