山东大学分子生物学相关资料

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Section A - Cells and macromolecules

1.The glycosylation of secreted proteins takes place in the . . .

A mitochondria.

B peroxisomes.

C endoplasmic reticulum.

D nucleus.

2.Which of the following is an example of a nucleoprotein?

A keratin.

B chromatin.

C histone.

D proteoglycan.

3.Which of the following is not a polysaccharide?

A chitin.

B amylopectin.

C glycosaminoglycan.

D glycerol.

4. Transmembrane proteins

A join two lipid bilayers together.

B have intra- and extracellular domains.

C are contained completely within the membrane.

D are easily removed from the membrane.

Section B - Protein structure

1. Which of the following is an imino acid?

A proline.

B hydroxy lysine.

C tryptophan.

D histidine.

2.Protein family members in different species that carry out the same biochemical role are described as . . .

A paralogs.

B structural analogs.

C heterologs.

D orthologs.

3. Which of the following is not a protein secondary structure?

B triple helix.

C double helix.

D ß-pleated sheet.

4.In isoelectric focusing, proteins are separated .

A in a pH gradient.

B in a salt gradient.

C in a density gradient.

D in a temperature gradient.

5.Edman degradation sequences peptides . . .

A using a cDNA sequence.

B according to their masses.

C From the C-terminus to the N-terminus.

D from the N-terminus to the C-terminus.

Section C - properties of nucleic acids

1.The sequence 5'-AGTCTGACT-3' in DNA is equivalent to which sequence in RNA?

A 5'-AGUCUGUGACU -3'

B 5' -UGTCTGUT

C -3'

C 5' -UCAGUCUGA-3'

D 5'- AGUCAGACU-3'

2. Which of the following correctly describes A-DNA?

A a right-handed antiparallel double helix with 10 bp/turn and bases lying perpendicular to the

helix axis.

B a left-handed antiparallel double-helix with 12 bp/turn formed from alternating pyrimidine-purine

sequences.

C a right-handed antiparallel double helix with 11 bp/turn and bases tilted with respect to the helix axis.

D a globular structure formed by short intramolecular helices formed in a single-strand nucleic acid.

3. Denaturation of double stranded DNA involves.

A preakage into short double-stranded fragments.

B separation into single strands.

C hydrolysis of the DNA backbone.

D cleavage of the bases from the sugar-phosphate backbone.

4. Which has the highest absorption per unit mass at a wavelength of 260 nm?

A double-stranded DNA.

B mononucleotides.

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