健康成人感觉神经传导相关影响因素及正常值范围研究_党静霞

中PCNA 表达的阳性率为(4410?6109)%,PCNA

指数为(7617?11118),较非侵袭性组明显增高,差异有统计学意义,认为PCNA 表达水平与肿瘤的侵袭能力相关。本研究与上述研究结果一致,表明PCNA 能够反映肿瘤的侵袭能力。

ER 、PTT G 和PCNA 与肿瘤的侵袭性密切相关,对肿瘤的发生、发展有重要作用,可作为临床判定腺瘤侵袭性分子标志和预后的判断指标,为泌乳素腺瘤的综合治疗提供依据。

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(收稿2009-01-20)

基金项目:陕西省科技攻关项目(2006K15)G3)作者简介:党静霞,女,副主任医师,主要从事临床神经电生理和周围神经病的研究

健康成人感觉神经传导相关影响因素及正常值范围研究

党静霞 刘 洁 陆文惠 李正仪

西安交通大学医学院第一附属医院神经内科 西安 710061

=摘要> 目的 研究影响健康成人感觉神经传导的相关因素,并建立正常值范围。方法 对213例正常成人的正中神经腕-示指、尺神经腕-小指和腓肠神经的感觉神经传导进行测定,分析其感觉传导各参数,结果按照不同年龄、性别、身高和体质量,分别进行统计学分析。结果 体质量、身高对感觉神经传导各参数影响不大;年龄是最主要的影响因素,主要影响正中神经感觉传导各参数、尺神经和腓肠神经感觉传导波幅,而这种影响在40岁前后最明显;性别仅对某些感觉神经传导参数有影响。结论 年龄和性别是影响感觉神经传导的主要因素,正常参考值的建立应参考年龄和性别。

=关键词> 感觉神经电位;感觉神经传导;反向法

=中图分类号> R33818 =文献标识码> A =文章编号> 1673-5110(2009)05-0004-04

The influence factors and normal values of sensory nerve conduction in healthy adults D ang J ingx ia,L iu J ie ,L u

Wenhui,et al 1Dep ar tment of N eur ology ,F irs t A f f iliated H os p ital of X i .an J iaotong Univ er sity ,X i .an 710061,China

=Abstract >Objective T o investig ate the influence factor s and no rmal v alues o f sensor y nerve conductio n (SNC)in healthy adults 1Methods T wo hundred and thir teen normal subjects w ere recruited,SN C studies were carr ied out on median nerv e wr ist to index finger ,ulnar nerv e w rist to lit tle finger and sur al nerve 1T he latency ,amplitude and co nduction v elo city of SN C par ameters wer e analy zed 1T he data collected w ere tabulated and analy zed based on different age g ro ups,sex ,w eig ht and height 1Results H eig ht and weight had no effect on the SN C par ameters 1Ho wev er,age had a signif icant effect on the SN C par ameters,mainly o n median sensor y parameter s and amplitude o f ulna r and sural sensor y nerve 1T he effect of ag e was mor e obvio us around 40year s old;G ender affected so me of the SN C parameters 1Conclusion Ag e and g ender wer e impor tant factor s when establishing the no rmative ranges of SN C 1

=Key words > Sensor y ner ve actio n potential;Senso ry nerv e conductio n;A nt idr omic technique