甘露醇注射液说明书英文版

The specifications of Mannitol Injection

【chemical composition】:D-mannitol

【Molecular formula】：C6H14O6

【molecular weight】：182.17

【Auxiliary materials】：Hydrochloric acid and sodium hydroxide

【Character】:The quality of this product is colorless clear liquid.

【Indications】: 1.tissue dehydrating medicine. It is used to treat brain edema caused by various reasons, reduce intracranial pressure and prevent cerebral hernia.

2.reduce intraocular pressure. It can effectively reduce intraocular pressure, which can be applied to other intraocular pressure lowering drugs or before intraocular surgery.

3.osmotic diuretic. It is used to identify oliguria caused by pre renal factors or acute renal failure. It can also be applied to prevent acute tubular necrosis caused by various causes.

4.as a supplementary diuretic measure to treat nephrotic syndrome and ascites due to cirrhosis, especially when hypoproteinemia occurs.

5.for some drug overdose or poison poisoning (such as barbiturate, lithium, salicylate and bromide), this drug can promote the excretion of the above substances and prevent renal toxicity.

ed as a washing agent for transurethral resection of prostate.

7.preoperative bowel preparation.

【specification】：250ml:50g

【Usage and dosage】: 1. adult: (1).Diuresis. The usual dosage is 1 to 2g/kg by weight, and 20% drops of 250ml are injected intravenously, and the dosage is adjusted to maintain 30 to 50ml urine per hour. (2)Treatment of cerebral edema, intracranial hypertension and glaucoma. According to body weight 0.25 to 2g/kg, the concentration was 15% to 25% in 30~60 minutes. When the patient is weak, the dose should be reduced to 0.5g/kg. The renal function was followed up closely. (3) Identification of pre renal oliguria and renal oliguria. According to the weight 0.2g/kg, 20% concentration in 3~5 minutes intravenous drip, such as after 2~3 hours after the medication, the urine volume is still less than 30~ 50ml, the maximum trial, if still no reaction should stop the drug. Patients with heart failure or heart failure are advised to use caution or not. (4) Prevention of acute renal tubular necrosis. First give 12.5 to 25g, 10 minutes intravenous drip, if no special situation, then 50g, 1 hours intravenous drip, if the urine can be maintained at more than 50ml per hour, then can continue to use 5% solution static drops; if ineffective, stop the drug immediately. (5)Treatment of drugs, poison poisoning.50g adjusted the dose by 20% drops of intravenous drip to maintain urine volume at 100 to 500ml per hour.

2.children.Diuresis. (1) According to body weight 0.25 to 2g/kg or by body surface area 60g/m2, intravenous infusion of 15% to 20% solution within 2~6 hours.

(2)Treatment of cerebral edema, intracranial hypertension and glaucoma. According to body weight 1 to 2g/kg or by body surface area 30 to 60g/m2, intravenous infusion of 15% to 20% concentration solution in 30~60 minutes. When the patient is weak, the dose is reduced to 0.5g/kg.

(3)Identification of pre renal oliguria and renal oliguria. According to the body weight 0.2g/kg or the body surface area 6g/m2, 15% ~ 25% concentration of intravenous drip for