血清胆红素水平和房颤的关系

大学第一附属医院心脏科住院的房颤患者98例为观察组，同期住院的非心房颤动患者80例为对照组。详细记录
入选患者的一般临床资料特征、合并疾病、实验室检查结果。采用经胸多普勒心脏超声测定左心房前后径、左心室
舒张末期内径和左心室射血分数等;采用单因素分析及Logistic回归分析血清胆红素水平和房颤的关系。结果
serum bilirubin levels and AF. Results After univariate analysis, serum bilirubin level in the control group
was significantly higher than that in the observation group: serum bilirubin ( 14.45 ±5.94) VS ( 11.96 ±
河南科技大学学报(医学版)
2019年9月第37卷第3期
文章编号:1672-688X(2019)03-0201-04
• 201 • DOI： 10.15926/j.cnki.issnl672-688x.2019.03.011
血清胆红素水平和房颤的关系
吴英乐'，程帅锋'，陈 润'，范孟楠'，杜来景'
ຫໍສະໝຸດ Baidu
摘 要：目的 探讨心房颤动与血清胆红素水平的关系。方法 选择2017年9月至2018年7月在河南科技
an independent risk factor for AF[ 0R(95%CZ) ,LAD 1.145( 1.061 ~ 1.23刀],serum bilirubin levels was an
independent protector of AF[ OR(95%CZ) ,TBIL 0.899(0.830*0.974) ]. Conclusion The high serum bili-
Henan University of Science and Technoloy, Luoyang 471003, China)
Abstract: Objective To investigate the potential relationship between the atrial fibrillation (AF) and
diastolic dimension ( LVEDD) and left ventricular ejection fraction ( LVEF) were determined by doppler
echocardiography. Univariate analysis and logistic regression were used to analyze the relationship between
bilirubin level. Methods Patients with and without AF hospitalized from September 2017 to July 2018 were
screened in this study. The final study population consisted of 178 patients: 98 patients with AF were
关键词：血清胆红素;心房颤动;氧化应激
中图分类号:R541.7
文献标志码：B
Relationship between Serum Bilirubin Level and Atrial Fibrillation
WU Ying-le1, CHENG Shuai-feng1, CHEN Run1, FAN Meng-nan2, DU Lai-jing1 (1.Department of Cardiovascular, The First Affiliated Hospital of Henan University of Science and Technoloy, Luoyang 471003, China； 2.Medical Records Statistics Section, The First Affiliated Hospital of
基金项目：临床科学家-菁英培训计划(CCA-CS-1725) 收稿日期：2019-03-18 作者单位：1.河南科技大学临床医学院，河南科技大学第一附属医院
enrolled, and 80 patients without AF were regard as the control group. The general clinical data, combined
disease and laboratory examination results were collected Left atrium diameter ( LAD) , left ventricular end-
对照组血清胆红素水平明显高于观察组，总胆红素(14.45±5.94) VS ( 11.96±4.38) ,P = 0.008；直接胆红素(2.79±
1.44) VS (2.07±0.83) ,P = 0.001；间接胆红素(11.66±4.94) VS (9.88±3.97) ,P = 0.026。多元 Logistic 回归分析显
示，左房扩大为房颤发生的独立危险因素[0R(95%CZ) ,LAD 1.145(1.061- 1.237)];血清胆红素为房颤发生的独
立保护因素[OR(95%C/) ,TBIL 0.899(0.830-0.974) ] o结论 血清胆红素可能是房颤的保护因素之一，两者之间
联系的可能机制有待于进一步研究。
4.38) ,P = 0.008； direct bilirubin (2.79± 1.44) VS (2.07±0.83) ,P = 0.001 ； indirect bilirubin (11.66±
4.94) VS (9.88±3.97) ,P = 0.026. After multivariate logistic regression analysis, left atrial enlargement was