红斑狼疮PPT

Pathogeny （病因）
• The exact cause of Lupus Erythematosus has not been found, which is the same as other autoimmune diseases. • Environmental pollution can also cause this diaease which should be pay attention to.
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Arthritis (关节炎）
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Fever
clinical symptoms
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Dermal pathology皮肤病理
Facial butterfly erythema（面部蝶形红斑）； disc erythema（ 盘形红斑）；dermatitis cause hair loss
Raynaud's phenomenon(雷诺现象）
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Pathological changes of skin including epidermal（表皮的） atrophy（萎缩）, necrosis（坏死） of the skin ulcers（溃疡） and edema（水肿）. Diffuse lesions(弥漫性病变) of the nervous system consist of fewer nerve cells, small vessel vasculitis, small infarction （梗塞）, necrosis and hemorrhage（出血）.
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Renault phenomenon is a loop around the disease. Under the stimulation such as cold or emotional tension, suddenly occurred in refers to small artery spasm.
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Genetic factors
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Infection factors
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Other factors
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Endocrine factors
Environmental factors
Clinical symptoms and detection methods
clinical symptoms
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Pathology （病理）
• Pathological morphology varies depending on the condition, location, large changes. • There are several common types.
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Vascular lesions form of necrotizing vasculitis of small vessels, including small arteries or arterioles.
Treatment and prevention of lupus erythematosus,LE
Treament
CLE
皮肤型红斑狼疮
SLE 系统性红斑狼疮
n,
红蝴蝶疮
In principle, CLE does not use hormones （激素） anti malaria drugs as the first choice.
2016年 CONTENT
Treatment and prevention of 03 lupus erythematosus,LE
6年 04 The latest research progress
Brief Introduction and etiopathogenesis (发病机理)
Brief Introduction
clinical symptoms
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Lymphatic system
About 50% of SLE patients with local or systemic lymph node enlargement,in neck, armpits, jaws swelling ， which are soft and no tenderness.
Those who has light symptom--- only mild rash, arthritis, pleurisy, don’t need hormene
1.Hormone therapy
• Corticosteroids • CTL • Immunoadsorption therapy 2.The psychological therapy of SLE The therapy includes “ revisiting ”---help . them lessen the intensity of emotion
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Oral or nasal pharyngeal ulcer (口腔及鼻咽部溃疡）
clinical symptoms
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Infection（传染性）？？？
Although the incidence of sle is far higher in our country than western countries, comparing with other common diseases is very rare. Because the patient is relatively small, a lot of people don't know much about this disease.when they see this disease ,they will want to know whether it is infectious？ The answer is no, sle will not spread by one person to another person. There are many factors occurring to reduce the body's immune tolerance, making the body's immune function disorder.Patients with the disease in the plateau can work, study, and participate in the activities of society like the normal
Patients with kidney disease will also have diaease of the renal glomerulus and renal tubules and interstitial and blood vessels. Cardiac abnormalities including pericarditis, myocarditis, heart valves and endocardial disease.
The latest research progress
1.Artemisinin can treat lupus (SLE)
SM934（水溶性青蒿素衍生物） is proved to be able to treat SLE
2. classification of CLE and the diagnose direct immunofluorescence and photoprovocation may be applied to confirm the diagnosis in specific cases.A revised scoring system, the Cutaneous Lupus Erythematosus Disease Area and Severity Index . (RCLASI) has recently been validated to assess disease activity and damage in CLE.
Fever
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Patients tend to be immunologic dysfunction,whose body can produce many kinds of substances, as a heat source and make the body heat.
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Arthritis(关节炎）
Here is one piece of picture with the symptom of skin.
Lupus 2016年 erythematosus
01 Brief Introduction and
20 16 年
etiopathogenesis(发病机理)
02 Clinical symptoms (临床症状）
prevention
1 Removal of possible incentives use medicine of SLE prudently； Avoid exposing to sun chronically （ use anti light agent ） 2 Keep optimistic 3 contraception （节育） If the patient have conceived,she had better do the treatment . of abortion 4 early diagnosis
Raynaud's phenomenon (雷诺现象）
Blood disorder(血液病变）
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Dermal pathology （皮肤病理）
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Infection Organ damage
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（传染性）