重组人干扰素α2b喷雾剂治疗手足口病的疗效观察

重组人干扰素α2b喷雾剂治疗手足口病的疗效观察
黄映
【期刊名称】《中国实用医药》
【年(卷),期】2014(000)008
【摘要】目的：评价重组人干扰素α2b喷雾剂治疗手足口病的临床疗效。

方法收治手足口病患儿174例，随机分为治疗组88例和对照组86例。

两组均给予热毒宁注射液、利巴韦林静滴治疗。

治疗组在对照组的基础上增加重组人干扰素α2b 喷雾剂局部治疗。

比较两组在发热消退时间、口腔疱疹消退时间、手足臀部疱疹消退时间及总病程等方面的变化和差异。

结果治疗组发热消退时间、口腔疱疹消退时间、手足臀部疱疹消退时间及总病程等均较对照组明显缩短，差异有统计学意义(P<0.05)。

结论重组人干扰素α2b喷雾剂治疗手足口病疗效显著，临床无明显不良反应。

%Objective To evaluate the curative effect of Recombinant Human Interferonα2b Spray in Hand-foot-and-mouth disease. Methods Totally 174 children with hand-foot-and-mouth disease were randomly divided into therapeutic group(88 cases) and control group(86 cases). Children in two groups were treated intervenously with reduning injection and ribavirin. Recombinant Human Interferon α2b Spray were increased in Therapeutic group.The total course and disappearance time of fever, oral herpes, hand foot and hip herpes were observed. Results The disappearance time of fever, oral herpes, hand foot and hip herpes and total course were shorter in the therapeutic group than those in the control group, the difference between the two groups was statistically
significantly(P<0.05). Conclusion The efficacy of Recombinant Human Interferonα2b Spray in Hand-foot-and-mouth disease are proved, no side effect observed.
【总页数】2页(P47-48)
【作者】黄映
【作者单位】363000 福建医科大学附属漳州市医院朝阳传染科
【正文语种】中文
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